Abstract:
BACKGROUND:CEA is widely used in the follow up of patients with colorectal carcinoma. AIM:To study the value of preoperative CEA as an independent prognostic factor in colorectal carcinoma. PATIENTS AND METHODS:Analysis of 373 operated patients (204 females, age range 21-92 years) with colorectal carcinoma and a mean follow up of 53 months. The cutoff value for CEA was 5 ng/ml. Ninety four percent of patients had an excisable tumor, 79% had involvement of perirectal/pericolonic adipose tissue and 46% had lymph node involvement. Staging was done using Dukes-Turnbull and TNM classifications. RESULTS:CEA was normal in 61% of cases, over 5 ng/ml in 39% and over 15 ng/ml in 22%. There was a strong correlation between mean preoperative CEA and tumor stage, depth and lymph node involvement. During the follow up, 140 patients died, 57 with normal and 83 with elevated CEA. Cancer mortality in patients subjected to a curative excision of the tumor (Dukes A-C2/TNM I-III) was 9% for colonic tumors and 36% for rectal tumors (p < 0.001). There were no survival differences in patients with Dukes B/TNM II tumors according to preoperative CEA. Among Dukes C/TNM III tumors, survival difference was only significant for rectal tumors. A Cox model disclosed tumor stage, location and preoperative CEA as independent prognostic factors for survival. CONCLUSIONS:CEA is an independent prognostic factor for survival in colorectal carcinoma and high levels suggest an advanced disease.
journal_name
Rev Med Chiljournal_title
Revista medica de Chileauthors
Bannura G,Cumsille MA,Contreras J,Barrera A,Melo C,Soto Ddoi
10.4067/s0034-98872004000600005subject
Has Abstractpub_date
2004-06-01 00:00:00pages
691-700issue
6eissn
0034-9887issn
0717-6163journal_volume
132pub_type
杂志文章abstract::The decrease in mortality in critical patient units led to an increase in intensive care unit acquired weakness (ICUAW), which significantly affects the functional performance and quality of life of patients. There are several scales that measure functionality in critical patients. The aim of this systematic review is...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872017000901137
更新日期:2017-09-01 00:00:00
abstract::Geographical inequalities arising in the death of children under 1 year are studied. Causes regarded as avoidable at the present moment and leading to death are determined and the 27 Regional Chilean Health Services are ranked from best to worse in levels of mortality using cluster analysis. Results show that: 1) t...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1982-04-01 00:00:00
abstract::Antibacterial potency of cephalosporins depends on inhibition (acylation) of one or more penicillin-binding proteins (PBP). Recently, reduced affinity of PBP for cephalosporins and other B-lactam agents has been found in some cases. Mechanism for these changes in affinity are analyzed in this review. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1989-09-01 00:00:00
abstract:BACKGROUND:Since February 2002, Flextend electrode catheters are used at the Cardiovascular Unit of the Catholic University Clinical Hospital. These transvenous catheters have an IS-1 connector, silicone coating, active fixation and retractile helix with dexamethasone acetate. AIM:To report early and one year results ...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872006000600011
更新日期:2006-06-01 00:00:00
abstract::Latrodectism, produced by the bite of Latrodectus spiders, is worldwide distributed, occurs in hot seasons, and affects mostly men when carrying out agricultural activities. The main symptoms are muscular pain and tremors, profuse perspiration, increased lacrimal, nasal and salival secretions, and hypertension. Sympto...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Postoperative hypocalcemia is one of the most common complications of thyroid surgery. It is related to the type of disease (malignant or benign), the number of identified parathyroid glands during the surgical procedure, and the surgeon's experience. Total thyroidectomy is the procedure of choice in our hos...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872007000100004
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abstract::A 37-year-old female with systemic lupus erythematosus and chronic treatment with steroids developed spontaneous bilateral rupture of tendons of both quadriceps muscles below the patella. Surgical treatment was undertaken with good results. The histologic features and a review of the literature are included. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1990-09-01 00:00:00
abstract::Both epidemiological and clinical evidence suggest a relationship between the prenatal environment and the risk of developing diseases during adulthood. The first observations about this relationship showed that prenatal growth retardation or stress conditions during fetal life were associated to cardiovascular, metab...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/s0034-98872006000100015
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abstract::The earth of ornamental plants is one of the main reservoirs of Aspergillus type of fungi in hospital areas. We studied 174 ornamental interior plants from a hospital at Santiago. Samples were obtained from the soil surface and sowed in Sabouraud-glucose agar, adding streptomycin and G-penicillin. After 72 h of cultur...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872014000500011
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1994-08-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1996-07-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000400528
更新日期:2018-04-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::Approximately, 10% of cirrhotic patients with ascites become refractory to medical treatment, a condition that reduces overall survival. TIPS is a therapeutic alternative for the management of refractory ascites. It corrects sinusoidal portal hypertension, becoming a rational and relatively safe therapeutic approach. ...
journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:
更新日期:1999-10-01 00:00:00
abstract::Background Sleep duration may be a risk factor for cognitive impairment. Aim To investigate the association between sleep duration and cognitive function in Chilean older adults. Material and Methods We analyzed information from 1,384 participants aged > 60 years participating in the National Health Survey 2009-2010 w...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872019001101398
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1991-08-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:Intensity modulated radiotherapy (IMRT) is an important step forward in cancer treatment. AIM:To report the first experience in Chile with IMRT for prostate cancer and compare the results obtained with different doses. PATIENTS AND METHODS:From January 1997 through June 2008, 156 patients with a mean age o...
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872011001100009
更新日期:2011-11-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/S0034-98872012000500002
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872006000200012
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journal_title:Revista medica de Chile
pub_type: 杂志文章,评审
doi:10.4067/S0034-98872015000600010
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journal_title:Revista medica de Chile
pub_type: 共识发展会议,杂志文章
doi:10.4067/S0034-98872009000800019
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010001200006
更新日期:2010-11-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:10.4067/s0034-98872018000901070
更新日期:2018-09-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:
更新日期:1995-05-01 00:00:00
abstract::This article deals with the history and evolution of student's scientific journals in Latin-America, their beginnings, how many still exist and which is their future projection. Relevant events show the growth of student's scientific journals in Latin-America and how are they working together to improve their quality....
journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010001200016
更新日期:2010-11-01 00:00:00
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journal_title:Revista medica de Chile
pub_type: 杂志文章
doi:/S0034-98872010000500015
更新日期:2010-05-01 00:00:00
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journal_title:Revista medica de Chile
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更新日期:2006-12-01 00:00:00