Quantitation of soluble HLA class I heterodimers and beta 2-microglobulin in patients with active pulmonary tuberculosis.

abstract：:Sera obtained from multiparous women and some of other origin contain antibodies which react with antigens on T cell subsets. These antibodies recognize two distinct diallelic systems, one of which is mainly present on T gamma cells while the other is present on T mu cells. The sera that reacted with the T gamma cells...

journal_title：Human immunology

authors： van Leeuwen A,Festenstein H,van Rood JJ

更新日期：1982-04-01 00:00:00

abstract：:Of 188 cases of Kaposi's sarcoma arising de novo after transplantation, HLA-A, -B typing was available for 135 and HLA-DR typing available for 67. Compared to the reported HLA phenotype frequencies of renal transplant recipients in the Southeast Organ Procurement Foundation (SEOPF), there is a significantly decreased ...

journal_title：Human immunology

authors： Brunson ME,Balakrishnan K,Penn I

更新日期：1990-09-01 00:00:00

abstract：:We have characterized the T lymphocyte population of the human neonate in respect of the expression of phenotypic profiles for naive, memory and differentiated populations. We have examined the response of the neonate T cell to the superantigen Staphylococcus enterotoxin B (SEB) and compared the response to T cells fr...

journal_title：Human immunology

authors： Macardle PJ,Wheatland L,Zola H

更新日期：1999-02-01 00:00:00

abstract：:There is considerable current interest in the application of Southern blotting and hybridization, with locus-specific HLA class II probes, to HLA typing. The work of several laboratories has shown that, under suitable conditions, restriction fragment patterns that correlate with DR and DQ serology and with DP cellular...

journal_title：Human immunology

authors： Bangham CR,Bushell A,Wood KJ,Morris PJ

更新日期：1988-02-01 00:00:00

abstract：:To evaluate the role of LMP (low molecular weight protein) genes as susceptibility markers for spondyloarthritis (SpA), LMP gene polymorphisms were analyzed in 223 Mexican patients with SpA (81 undifferentiated SpA [U-SpA], 117 with ankylosing spondylitis [AS], 25 with reactive arthritis) and in 139 ethnically matched...

journal_title：Human immunology

authors： Vargas-Alarcón G,Gamboa R,Zuñiga J,Fragoso JM,Hernández-Pacheco G,Londoño J,Pacheco-Tena C,Cardiel MH,Granados J,Burgos-Vargas R

更新日期：2004-12-01 00:00:00

abstract：:Interleukin-8 (IL-8), a potent chemoattractant, has been demonstrated to contribute to human cancer progression through its potential functions as a mitogenic, angiogenic, and motogenic factor. We designed a broad study to investigate whether genetic variation in IL-8 has implications for susceptibility to and prognos...

journal_title：Human immunology

authors： Snoussi K,Mahfoudh W,Bouaouina N,Ahmed SB,Helal AN,Chouchane L

更新日期：2006-01-01 00:00:00

abstract：:The LABScreen single antigen bead assay (SAB) is a method widely used for the identification and monitoring of human leukocyte antigen (HLA) antibodies in patients pre-and post-transplant. While accurate testing of patient samples is key for optimal patient care, time can also be important, especially during deceased ...

journal_title：Human immunology

authors： Liwski RS,Greenshields AL,Murphey C,Bray RA,Gebel HM

更新日期：2017-01-01 00:00:00

abstract：:The 5' cis-regulatory region of the CCR5 gene exhibits a strong signature of balancing selection in several human populations. Here we analyze the polymorphism of this region in Amerindians from Amazonia, who have a complex demographic history, including recent bottlenecks that are known to reduce genetic variability....

journal_title：Human immunology

authors： Ramalho RF,Santos EJ,Guerreiro JF,Meyer D

更新日期：2010-09-01 00:00:00

abstract：:A panel of 34 clones was established from a cell line derived from the skin biopsy of a patient (genotype: A1, A2, B7, B8, DR3, DR6) undergoing acute graft-versus-host disease after semiallogeneic bone marrow transplantation with his mother's bone marrow (genotype: A1, A1, B7, B8, DR3, DR6). The T-cell line obtained p...

journal_title：Human immunology

authors： Vié HP,Millpied N,Devilder MC,Mahe B,Hallet MM,Moreau JF,Soulillou JP

更新日期：1990-10-01 00:00:00

abstract：:HLA-DQA1 typing of the 4AOHW cell panel is presented using a novel strategy that exploits both intron and exon polymorphisms. Intron sequences adjacent to the variable HLA-DQA1 second exon exhibit stable polymorphisms that are specific for locus alleles and certain suballelic DR/DQ haplotypes. A PCR-RFLP method has be...

journal_title：Human immunology

authors： Limm TM,Ashdown ML,Naughton MJ,McGinnis MD,Simons MJ

更新日期：1993-09-01 00:00:00

abstract：:The relevance of pre-existing HLA-antibodies (HLA-Ab) in liver transplantation (LTx) is controversial. While livers are allocated without HLA match or preoperative crossmatch testing, several studies point to an impact of donor specific antibodies (DSA) for acute rejection, bile duct complications or even graft loss. ...

journal_title：Human immunology

authors： Koch M,Marget M,Sterneck M,Fischer L,Thude H,Nashan B

更新日期：2018-07-01 00:00:00

abstract：:Behçet's disease (BD) has been established to be associated with HLA-B51. However, it has not been revealed whether the HLA-B51 gene itself or another gene located near the HLA-B gene is directly involved in the pathogenesis of BD. Previously, using Japanese BD patients, our group has narrowed down a BD-causative gene...

journal_title：Human immunology

authors： Mizuki N,Yabuki K,Ota M,Verity D,Katsuyama Y,Ando H,Onari K,Goto K,Imagawa Y,Mandanat W,Fayyad F,Stanford M,Ohno S,Inoko H

更新日期：2001-02-01 00:00:00

abstract：:The suppressive effects of CD4+CD25+ regulatory T cells (Tregs) on T cells have been well documented. Here we investigated whether human CD4+CD25+ Tregs can inhibit the proinflammatory properties of monocytes/macrophages. Monocytes and T cells were isolated from peripheral blood of healthy volunteers by magnetic cell ...

journal_title：Human immunology

authors： Taams LS,van Amelsfort JM,Tiemessen MM,Jacobs KM,de Jong EC,Akbar AN,Bijlsma JW,Lafeber FP

更新日期：2005-03-01 00:00:00

abstract：:Our objective was to study a possible contribution of MHC genes to S-HLA-I secretion in patients with Type I diabetes. Quantitatively, we used a highly sensitive enzyme-linked immunoassay to measure S-HLA-I in the serum of a total of 39 patients with Type I diabetes, as well as 36 kinships of 12 diabetic patients and ...

journal_title：Human immunology

authors： Adamashvili I,McVie R,Gelder F,Gautreaux M,Jaramillo J,Roggero T,McDonald J

更新日期：1997-07-01 00:00:00

abstract：:This report describes a new MHC class II allele, HLA-DR beta 1*0306, discovered in a 31-year-old Norwegian male. The allele typed serologically as DRw52 (DR3) and amplified in PCR using DR52-associated group primers. This product could not be identified using established restriction digests, however. Use of Asp 700, M...

journal_title：Human immunology

authors： Fenske B,Lemieux J,Hoar D,Fitzpatrick J,Keown P

更新日期：1996-03-01 00:00:00

abstract：:The association of rs12979860 and rs8099917 single nucleotide polymorphisms (SNPs) near IL28B with sustained virological response (SVR) in hepatic allograft recipients undergoing treatment with PEGylated interferon (PEG-IFN) plus ribavirin (RBV) for recurrent hepatitis C virus (HCV) infection remains inconclusive. We ...

journal_title：Human immunology

authors： Zhang L,Lu Q,Yang Z,Wang X,Cai L,Liu X,Liao R,Yang X,Chen Y,Yang Z

更新日期：2014-12-01 00:00:00

abstract：:The pattern of lymphocyte growth from endomyocardial biopsies in 55 heart transplant recipients was shown to be correlated with the subsequent development of graft coronary disease. Persistent lymphocyte growth was observed in 39 patients, and 15 of these growers (or 41%) developed graft coronary disease. In contrast,...

journal_title：Human immunology

authors： Kaufman CL,Zeevi A,Kormos RL,Zerbe TR,Keenan RJ,Uretsky BF,Griffith BP,Hardesty RL,Duquesnoy RJ

更新日期：1990-06-01 00:00:00

abstract：:Idiopathic achalasia is an esophageal motor disorder of unknown etiology. A wealth of evidence supports the concept that achalasia is an immune-mediated disease. According to this evidence, achalasia has been significantly associated with specific alleles of the human leukocyte antigen class II, PTPN22 and IL23R. Seve...

journal_title：Human immunology

authors： Nuñez C,García-González MA,Santiago JL,Benito MS,Mearín F,de la Concha EG,de la Serna JP,de León AR,Urcelay E,Vigo AG

更新日期：2011-09-01 00:00:00

abstract：:FOXP3(+) regulatory T cells, a unique subset of T cells, are critical for orchestrating an immune response and preventing self-reactivity. With the increasing prevalence and unsatisfactory treatment of autoimmunity, allergic diseases, cancer and chronic infections, much attention has been focused on understanding thei...

journal_title：Human immunology

authors： Tran DQ,Shevach EM

更新日期：2009-05-01 00:00:00

abstract：:Indirect immunofluorescence staining with monoclonal antibodies has shown a differential distribution of HLA-DR, DQ, and DP antigens in normal tissues of nonlymphoid origin. The distribution of HLA-DP antigens is similar to that of HLA-DR antigens, while that of HLA-DQ antigens is more restricted. Malignant transforma...

journal_title：Human immunology

authors： Natali P,Bigotti A,Cavalieri R,Nicotra MR,Tecce R,Manfredi D,Chen YX,Nadler LM,Ferrone S

更新日期：1986-02-01 00:00:00

abstract：:Immunoglobulin idiotypes (Id) of malignant B cells represent highly specific markers which can be used for vaccination. PCR-amplification of immunoglobulin genes enables the rapid production of large amounts of Id vaccines. However, the separate amplification and subsequent recombination of heavy and light chains can ...

journal_title：Human immunology

authors： Terness P,Welschof M,Moldenhauer G,Jung M,Moroder L,Kirchhoff F,Kipriyanov S,Little M,Opelz G

更新日期：1997-08-01 00:00:00

abstract：:With a larger, independent cohort and more sophisticated measures, we sought to confirm our work that indicated independence of humoral and cellular immunity following measles vaccination. We recruited an age-stratified random cohort of 764 healthy subjects from all socioeconomic strata, all with medical-record docume...

journal_title：Human immunology

authors： Jacobson RM,Ovsyannikova IG,Vierkant RA,Pankratz VS,Poland GA

更新日期：2012-05-01 00:00:00

abstract：:Polymorphisms present in the TNF promoter region has shown to influence the gene transcription. Leprosy displays different clinical manifestations according to the immune responses of the individual infected with Mycobacterium leprae. In this study, we evaluated the single nucleotide polymorphisms (SNPs) -238 G/A (rs3...

journal_title：Human immunology

authors： Silva GA,Ramasawmy R,Boechat AL,Morais AC,Carvalho BK,Sousa KB,Souza VC,Cunha MG,Barletta-Naveca RH,Santos MP,Naveca FG

更新日期：2015-03-01 00:00:00

abstract：:We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 144 Mexicans from the state of Guerrero to obtain information regarding allelic and haplotypic frequencies. We find that the ten most frequent haplotypes in the state of Guerrero include eight Native American and two E...

journal_title：Human immunology

authors： Juárez-Nicolás F,Barquera R,Martínez-Álvarez JC,Hernández-Zaragoza DI,Ortega-Yáñez A,Arrieta-Bolaños E,Clayton S,Bravo-Acevedo A,Arrazola-García MA,Immel A,Juárez-Barreto V,Benítez-Arvizu G,Vega-Martínez MDR,García-Álvarez R,

更新日期：2020-09-01 00:00:00

abstract：:There are four DRw8 haplotypes with different DQ alleles in Japanese: DRw8-DQw6 (w1), DRw8-DQw4, DRw8-DQw8(w3), and DRw8-DQw7 (w3). We previously reported the nucleotide sequence of DRB1 gene of DRw8-DQw6(w1) and it was named DRB1*08032. The nucleotide sequences of the other DRw8 DRB1 alleles and their correspondence ...

journal_title：Human immunology

authors： Watanabe Y,Matsushita S,Kohsaka T,Kobayashi N,Nose Y,Tokunaga K,Juji T

更新日期：1992-07-01 00:00:00

abstract：:Rat soluble MHC class I synthesis was studied at both RNA and protein levels to determine whether multiple forms of soluble MHC class I molecules are produced by different mechanisms. RT-PCR and sequencing of MHC class I transcripts identified an alternatively spliced nonclassical MHC class I gene product, lacking bot...

journal_title：Human immunology

authors： Zhai Y,Knechtle S

更新日期：1998-07-01 00:00:00

abstract：:Two members of a unique class of natural antibodies have been identified in all of a large cohort of sera from clinically normal humans of broad age distribution. By means of a series of 10-12 mer peptides the epitope for each of those antibodies was characterized with regard to amino acid identity and conformation. S...

journal_title：Human immunology

authors： Rodman TC,To SE,Sullivan JJ,Winston R

更新日期：1997-07-01 00:00:00

abstract：:DNA sequence-based typing at the HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, -DRB1, and -DRB3/4/5 loci was performed on samples provided by 159 individuals from the Worcester region of the Western Cape province of South Africa. The purpose of the study was to characterize allele frequencies in the local population, to ...

journal_title：Human immunology

authors： Grifoni A,Sidney J,Carpenter C,Phillips E,Mallal S,Scriba TJ,Sette A,Lindestam Arlehamn CS

更新日期：2018-03-01 00:00:00

abstract：:Human ficolin-2 (L-ficolin; FCN2) is a serum protein binding to sugar moieties of different human micro-pathogens forcing phagocytosis. Here, we investigate the clinical significance of FCN2 in African children with either mild or severe malaria (n = 130 and n = 108, respectively) from Gabon by analyzing three promote...

journal_title：Human immunology

authors： Faik I,Oyedeji SI,Idris Z,de Messias-Reason IJ,Lell B,Kremsner PG,Kun JF

更新日期：2011-01-01 00:00:00

abstract：:The role of HLA-G in several clinical conditions related to reproduction has been investigated. Important polymorphisms have been found within the 5'URR and 3'UTR regions of the HLA-G promoter. The aim of the present study was to investigate 16 SNPs in the 5'URR and 14-bp insertion/deletion (ins/del) polymorphism loca...

journal_title：Human immunology

authors： Costa CH,Gelmini GF,Wowk PF,Mattar SB,Vargas RG,Roxo VM,Schuffner A,Bicalho Mda G

更新日期：2012-09-01 00:00:00