Dose perturbation effects in prostate seed implant brachytherapy with I-125.

abstract：:We examined the reasons for the reduction in response of a multidetector radiation counting system when operated at high count-rates and established a convenient method of correction which is accurate to within +/- 1% up to 0-6 X 10(5) counts per second. In its application the method uses the observed count-rates from...

journal_title：Physics in medicine and biology

authors： Oxby CB,Oldroyd B,Appleby DB

更新日期：1976-01-01 00:00:00

abstract：:The architecture of multi-layer imagers (MLIs) can be exploited to provide megavoltage spectral imaging (MVSPI) for specific imaging tasks. In the current work, we investigated bone suppression and gold fiducial contrast enhancement as two clinical tasks which could be improved with spectral imaging. A method based on...

journal_title：Physics in medicine and biology

authors： Myronakis M,Hu YH,Fueglistaller R,Wang A,Baturin P,Huber P,Morf D,Star-Lack J,Berbeco R

更新日期：2018-05-10 00:00:00

abstract：:Improving the prevention and detection of preinvasive ductal carcinoma in situ (DCIS) is expected to lower both morbidity and mortality from breast cancer. Transgenic mouse models can be used as a 'test bed' to develop new imaging methods and to evaluate the efficacy of candidate preventive therapies. We hypothesized ...

journal_title：Physics in medicine and biology

authors： Jansen SA,Conzen SD,Fan X,Krausz T,Zamora M,Foxley S,River J,Newstead GM,Karczmar GS

更新日期：2008-10-07 00:00:00

abstract：:An X-ray technique has been developed to enable reproducible and quantitative data to be obtained from radiographs taken by a diagnostic X-ray machine. Careful attention has been paid to the alignment of the specimen and the diagnostic tube and to operating conditions. The choice of X-ray spectrum is described togethe...

journal_title：Physics in medicine and biology

authors： King SD

更新日期：1977-07-01 00:00:00

abstract：:The purpose of this study was to develop a method to simulate breathing motion induced interplay effects for volumetric modulated arc therapy (VMAT), to verify the proposed method with measurements, and to use the method to investigate how interplay effects vary with different patient- and machine specific parameters....

journal_title：Physics in medicine and biology

authors： Edvardsson A,Nordström F,Ceberg C,Ceberg S

更新日期：2018-04-19 00:00:00

abstract：:The amount of silica in the human lung may be estimated by measurement of silicon using in vivo neutron activation analysis. A pulsed, fast neutron beam, produced with a 2 MV Van de Graaff generator using the 2H + 2H reaction, was used to irradiate a Si-doped chest phantom in order to determine minimum detection limit...

journal_title：Physics in medicine and biology

authors： Kacperek A,Ryde SJ,Evans CJ,Dutton J,Morgan WD,Sivyer A

更新日期：1993-06-01 00:00:00

abstract：:Planning of radiotherapy is often difficult due to restrictions on morphological images. New imaging techniques enable the integration of biological information into treatment planning and help to improve the detection of vital and aggressive tumour areas. This might improve clinical outcome. However, nowadays morphol...

journal_title：Physics in medicine and biology

authors： Neff T,Kiessling F,Brix G,Baudendistel K,Zechmann C,Giesel FL,Bendl R

更新日期：2005-09-07 00:00:00

abstract：:Range verification in proton therapy is a critical quality assurance task. We studied the feasibility of online range verification based on proton-induced acoustic signals, using a bidirectional long-short-term-memory recurrent neural network and various signal processing techniques. Dose distribution of 1D pencil pro...

journal_title：Physics in medicine and biology

authors： Yao S,Hu Z,Zhang X,Lou E,Liang Z,Wang Y,Peng H

更新日期：2020-11-05 00:00:00

abstract：:A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear sim...

journal_title：Physics in medicine and biology

authors： Midgley SM

更新日期：2014-12-07 00:00:00

abstract：:Recently, deep learning technology has achieved various successes in medical image analysis studies including computer-aided diagnosis (CADx). However, current CADx approaches based on deep learning have a limitation in interpreting diagnostic decisions. The limited interpretability is a major challenge for practical ...

journal_title：Physics in medicine and biology

authors： Kim ST,Lee JH,Lee H,Ro YM

更新日期：2018-12-04 00:00:00

abstract：:Coincidence resolving time (CRT) is one of the most important physical-performance measures for positron emission tomography (PET), as reconstruction with accurate time-of-flight information enhances the lesion detectability in patient studies. Accordingly, various PET detector designs and high-performance front-end r...

journal_title：Physics in medicine and biology

authors： Park H,Lee S,Ko GB,Lee JS

更新日期：2018-12-10 00:00:00

abstract：:Using Monte Carlo simulation of 99Tcm single-photon-emission computed tomography (SPECT), we investigate the effects of tissue-background activity, tumour location, patient size, uncertainty of energy windows, and definition of tumour region on the accuracy of quantification. The dual-energy-window method of correctio...

journal_title：Physics in medicine and biology

authors： Luo JQ,Koral KF,Ljungberg M,Floyd CE Jr,Jaszczak RJ

更新日期：1995-01-01 00:00:00

abstract：:Four dimensional cone beam computed tomography (4DCBCT) uses a constant gantry speed and imaging frequency that are independent of the patient's breathing rate. Using a technique called respiratory motion guided 4DCBCT (RMG-4DCBCT), we have previously demonstrated that by varying the gantry speed and imaging frequency...

journal_title：Physics in medicine and biology

authors： O'Brien RT,Stankovic U,Sonke JJ,Keall PJ

更新日期：2017-06-07 00:00:00

abstract：:A theoretical analysis is presented of the biologically effective dose of the solar long wave ultraviolet radiation (UVA) received by patients who are being treated for psoriasis by oral psoralen photochemotherapy. It is shown that patients treated during the summer months in the UK may well receive a UV dose which is...

journal_title：Physics in medicine and biology

authors： Diffey BL

更新日期：1981-11-01 00:00:00

abstract：:In this paper, we present a new algorithm as an enhancement and preprocessing step for acquired optical coherence tomography (OCT) images of the retina. The proposed method is composed of two steps, first of which is a denoising algorithm with wavelet diffusion based on a circular symmetric Laplacian model, and the se...

journal_title：Physics in medicine and biology

authors： Kafieh R,Rabbani H,Abramoff MD,Sonka M

更新日期：2013-05-07 00:00:00

abstract：:The interactions between energetic ions and biological and/or organic target materials have recently attracted theoretical and experimental attention, due to their implications for detector and device technologies, and for therapeutic applications. Most of the attention has focused on detection of the primary ionizati...

journal_title：Physics in medicine and biology

authors： Falzone N,Myhra S,Chakalova R,Hill MA,Thomson J,Vallis KA

更新日期：2013-11-07 00:00:00

abstract：:The temperature sensitivities of absorption and reduced scattering coefficients in the range 700-1000 nm are determined for the liquid phantom Intralipid using spatially resolved continuous wave measurements. The measurements were conducted on a 10 L heated volume of 1% Intralipid subjected to a 40-30 degrees C coolin...

journal_title：Physics in medicine and biology

authors： McGlone VA,Martinsen P,Künnemeyer R,Jordan B,Cletus B

更新日期：2007-05-07 00:00:00

abstract：:An extensive study on specific absorption rate (SAR) covering 720 simulations and 15 voxel models (18-105 kg) has been performed by applying the parallel finite-difference time-domain method. High-resolution whole-body models have been irradiated with plane waves from 300 MHz to 5 GHz by applying various incoming dire...

journal_title：Physics in medicine and biology

authors： Uusitupa T,Laakso I,Ilvonen S,Nikoskinen K

更新日期：2010-02-21 00:00:00

abstract：:Reducing radiation dose in dual energy computed tomography (DECT) is highly desirable but it may lead to excessive noise in the filtered backprojection (FBP) reconstructed DECT images, which can inevitably increase the diagnostic uncertainty. To obtain clinically acceptable DECT images from low-mAs acquisitions, in th...

journal_title：Physics in medicine and biology

authors： Zhang H,Zeng D,Lin J,Zhang H,Bian Z,Huang J,Gao Y,Zhang S,Zhang H,Feng Q,Liang Z,Chen W,Ma J

更新日期：2017-07-07 00:00:00

abstract：:Diffusion weighted magnetic resonance imaging offers a non-invasive tool to explore the three-dimensional structure of brain white matter in clinical practice. Anisotropic diffusion hardware phantoms are useful for the quantitative validation of this technique. This study provides guidelines on how to manufacture anis...

journal_title：Physics in medicine and biology

authors： Fieremans E,De Deene Y,Delputte S,Ozdemir MS,Achten E,Lemahieu I

更新日期：2008-10-07 00:00:00

abstract：:The goal of this study is to demonstrate the feasibility of a novel non-coplanar-arc optimization algorithm (CyberArc). This method aims to reduce the delivery time of conventional CyberKnife treatments by allowing for continuous beam delivery. CyberArc uses a 4 step optimization strategy, in which nodes, beams, and c...

journal_title：Physics in medicine and biology

authors： Kearney V,Cheung JP,McGuinness C,Solberg TD

更新日期：2017-06-26 00:00:00

abstract：:The purpose of this work was to use Monte Carlo simulations to verify the accuracy of the dose distributions from a commercial treatment planning optimization system (Corvus, Nomos Corp., Sewickley, PA) for intensity-modulated radiotherapy (IMRT). A Monte Carlo treatment planning system has been implemented clinically...

journal_title：Physics in medicine and biology

authors： Ma CM,Pawlicki T,Jiang SB,Li JS,Deng J,Mok E,Kapur A,Xing L,Ma L,Boyer AL

更新日期：2000-09-01 00:00:00

abstract：:The absolute dose rate around beta sources for intravascular brachytherapy was measured with thin thermoluminescent (TL) dosimeters and radiochromic film. The calibration of these dosimeters was performed at the dose maximum in a 6 MeV electron beam of a linear accelerator. Compared to the values given by the manufact...

journal_title：Physics in medicine and biology

authors： Piessens M,Reynaert N

更新日期：2000-08-01 00:00:00

abstract：:Beam hardening is inevitable due to the polychromatic X-ray spectrum and energy-dependent attenuation coefficients of materials, leading to the underestimation of artifacts arising from projection data, especially on metal regions. State-of-the-art research on beam-hardening artifacts is based on a numerical method th...

journal_title：Physics in medicine and biology

authors： Hur J,Kim D,Shin YG,Lee H

更新日期：2021-01-26 00:00:00

abstract：:Discrete implanted liver tumours in the rat have been exposed to arrays of 1.7 MHz ultrasound lesions. Focal peak intensities in the range 1.4-3.5 k Wcm-2 were used for an exposure time of 10 s. It has been demonstrated that where the whole tumour volume was exposed to the focused ultrasound beam, no evidence of tumou...

journal_title：Physics in medicine and biology

authors： ter Haar G,Rivens I,Chen L,Riddler S

更新日期：1991-11-01 00:00:00

abstract：:To evaluate a commercial synthetic CT (syn-CT) software for use in prostate radiotherapy. Twenty-five prostate patients underwent CT and MR simulation scans in treatment position on a 3T MR scanner. A commercially available MR protocol was used that included a T2w turbo spin-echo sequence for soft-tissue contrast and ...

journal_title：Physics in medicine and biology

authors： Tyagi N,Fontenla S,Zhang J,Cloutier M,Kadbi M,Mechalakos J,Zelefsky M,Deasy J,Hunt M

更新日期：2017-04-21 00:00:00

abstract：:A mathematical model has been constructed to simulate the response of cells in vitro to fractionated doses of radiation. The model is capable of describing most of the radiobiological functions that are commonly studied. Input data are measurable cell properties. The details of the model and methods of acquiring the i...

journal_title：Physics in medicine and biology

authors： Niederer J,Cunningham JR

更新日期：1976-09-01 00:00:00

abstract：:Fast heat extraction is critically important to obtain the maximal benefit of cryogen spray cooling (CSC) during laser therapy of shallow skin lesions, such as port wine stain birthmarks. However, a film of liquid cryogen can build up on the skin surface, impairing heat transfer due to the relatively low thermal condu...

journal_title：Physics in medicine and biology

authors： Majaron B,Svaasand LO,Aguilar G,Nelson JS

更新日期：2002-09-21 00:00:00

abstract：:This paper extends the kernel method that was proposed previously for dynamic PET reconstruction, to incorporate anatomical side information into the PET reconstruction model. In contrast to existing methods that incorporate anatomical information using a penalized likelihood framework, the proposed method incorporate...

journal_title：Physics in medicine and biology

authors： Hutchcroft W,Wang G,Chen KT,Catana C,Qi J

更新日期：2016-09-21 00:00:00

abstract：:As a part of an ongoing effort to develop computerized planning tools for cryosurgery, an experimental study has been conducted to verify a recently developed numerical technique for bioheat transfer simulations. Experiments were performed on gelatin solution as a phantom material, using proprietary liquid-nitrogen cr...

journal_title：Physics in medicine and biology

authors： Rossi MR,Rabin Y

更新日期：2007-08-07 00:00:00