Abstract:
:A method for quantifying shape variability, the jiggle, or motor unit potentials (MUPs) recorded with conventional EMG electrodes is presented. Amplitude variability at each point of time of the MUP was analyzed. Two new parameters are proposed: the normalized value of the consecutive amplitude differences (CAD), and the cross-correlational coefficient of the consecutive discharges (CCC). Simulations showed that increased jitter of the constituent single fiber potentials increases the jiggle as expressed by an increase in CAD and decrease in CCC values. Even when the jitter value of each component was fixed, increased temporal dispersion increased the jiggle whereas an increased number of fibers decreased the jiggle. This new method has been applied in normal subjects, patients with chronic neurogenic diseases and patients with ALS. Jiggle was significantly increased in the ALS group, in agreement with visual observations. We believe that this method for quantifying jiggle will increase the information obtainable from routine EMG investigations.
journal_name
Muscle Nervejournal_title
Muscle & nerveauthors
Stålberg EV,Sonoo Mdoi
10.1002/mus.880171003subject
Has Abstractpub_date
1994-10-01 00:00:00pages
1135-44issue
10eissn
0148-639Xissn
1097-4598journal_volume
17pub_type
临床试验,杂志文章相关文献
MUSCLE & NERVE文献大全abstract:INTRODUCTION:Skin-derived precursor cells (SKPs) are neural crest progenitor cells that can attain a Schwann cell-like phenotype through in vitro techniques (SKP-SCs). We hypothesized that SKP-SCs could produce mature myelin and, in doing so, facilitate the recovery of a focal demyelination injury. METHODS:We unilater...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24136
更新日期:2014-08-01 00:00:00
abstract:INTRODUCTION:Premotor potentials (PMPs) precede compound muscle action potentials evoked from the second lumbrical muscle after median nerve stimulation. Although PMP has been identified as a median sensory nerve action potential, few reports have documented the significance of PMP parameters for diagnosing carpal tunn...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23424
更新日期:2012-12-01 00:00:00
abstract::A patient in perfect health prior to electrical shock developed an ALS-like syndrome after the shock. Onset of the disease occurred in the limb through which the shock entered, and subsequently followed a course well-described in previous case reports. Possible mechanisms of disease are discussed. ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.880141008
更新日期:1991-10-01 00:00:00
abstract:INTRODUCTION:Patients with self-limited statin-related myopathy improve spontaneously when statins are stopped. In contrast, patients with statin-associated autoimmune myopathy have autoantibodies recognizing 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) and usually require immunosuppressive therapy to contr...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25127
更新日期:2016-06-01 00:00:00
abstract::Requirements for ethical review of research involving human subjects are based on widely accepted international standards that are implemented by various national regulations and institutional policies. In the United States, most human research is reviewed by institutional review boards (IRBs) applying federal standar...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.10398
更新日期:2003-07-01 00:00:00
abstract::Mutations of the valosin-containing protein gene (VCP) are responsible for autosomal-dominant hereditary inclusion-body myopathy associated with frontotemporal dementia and Paget's disease of bone. We identified the p.R155C missense mutation in the VCP gene segregating in an Italian family with three affected siblings...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20890
更新日期:2008-01-01 00:00:00
abstract::The Moberg Pick-Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the hand occurs with aging, the effect of age on a subject's performance of the Moberg Pick-Up Test has not been examined. The primary goal of this study was to examine the impact of aging and, secondarily, ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20750
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:Stroke-related changes in maximal dynamic hip flexor muscle fatigability may be more relevant functionally than isometric hip flexor fatigability. METHODS:Ten chronic stroke survivors performed 5 sets of 30 hip flexion maximal dynamic voluntary contractions (MDVC). A maximal isometric voluntary contractio...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.24520
更新日期:2015-03-01 00:00:00
abstract::The development of the personal computer has simplified the process of quantitating sensory thresholds using various testing algorithms. We reviewed the technical aspects and reproducibility of different methods to determine threshold for light touch-pressure, vibration, thermal, and pain stimuli. Clinical uses and li...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.20053
更新日期:2004-05-01 00:00:00
abstract::A stand-alone ultrasound shear wave imaging technology has been developed to quantify and visualize Young's modulus distribution by remotely applying ultrasound radiation force and tracking the resulting microvibrations in soft tissues with ultrafast ultrasound imaging. We report the first preliminary data that detect...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21723
更新日期:2010-09-01 00:00:00
abstract::Muscle fatigue or neuromuscular disease may result in central activation failure during maximal voluntary contractions (MVCs). Superimposition of an electrically stimulated contraction during an MVC has been used to detect central activation failure. To determine the most sensitive means of quantitating central activa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(SICI)1097-4598(199607)19:7<861::AID-MUS8>
更新日期:1996-07-01 00:00:00
abstract::Epidemiological data suggest that prolonged exposure to cyclic lumbar flexion elicits a chronic neuromuscular disorder and disability in workers. This study provides a physiological and biomechanical assessment of various repetitions of cyclic lumbar flexion sessions as a risk factor for development of an acute neurom...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20629
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:Neuromuscular activation can be influenced by both muscle temperature (Tm) and fatigue. METHODS:To assess the effects of Tm and fatigue on the electromechanical delay (EMD), 15 participants performed voluntary isometric contractions of different intensities under neutral (TmN), low (TmL), and high (TmH) T...
journal_title:Muscle & nerve
pub_type: 杂志文章,随机对照试验
doi:10.1002/mus.23627
更新日期:2013-04-01 00:00:00
abstract::Limb-girdle muscular dystrophy type 2A (LGMD2A) is an autosomal-recessive disorder characterized by selective atrophy and progressive weakness of proximal girdle muscles. LGMD2A, the most prevalent form of LGMD, is caused by mutations in the CAPN3 gene that encodes the skeletal muscle-specific member of the calpain fa...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20480
更新日期:2006-03-01 00:00:00
abstract::The first dorsal interosseous (FDI) and abductor digiti minimi (ADM) muscles are innervated by the same ulnar nerve, but studies have shown that the former is much more severely affected in amyotrophic lateral sclerosis. In this study, threshold tracking was used to investigate whether membrane properties differ betwe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21107
更新日期:2009-03-01 00:00:00
abstract::Many post-polio patients develop new muscle weakness decades after the initial illness. However, its mechanism and treatment are controversial. The purpose of this study was to test the hypotheses that: (1) after strength training, post-polio patients show strength improvement comparable to that seen in the healthy el...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/mus.10327
更新日期:2003-03-01 00:00:00
abstract::We report an 18-month-old Charcot-Marie-Tooth type 1A (CMT1A) patient who developed a rapid-onset neuropathy, with proximal and distal weakness, and non-uniform nerve conduction studies. The neuropathy responded well to immunomodulation, confirming the coexistence of an inherited and an inflammatory neuropathy. Unexpe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21753
更新日期:2010-10-01 00:00:00
abstract::Skeletal muscle cells are hypertrophied by mechanical stresses, but the underlying molecular mechanisms are not fully understood. Two signaling pathways, phosphatidylinositol 3-kinase (PI3K)/Akt to target of rapamycin (TOR) and extracellular signal-regulated kinase kinase (MEK) to extracellular signal-regulated kinase...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21473
更新日期:2010-01-01 00:00:00
abstract::Being the smallest functional units under neural control, motor units play an integral role in muscle physiology. However, at the present time, there does not exist any widely accepted technique for quantifying or estimating the number of motor units in a muscle. Specifically, the existing techniques are the increment...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.880131108
更新日期:1990-11-01 00:00:00
abstract::Eleven patients with previous polio were studied. The concentration of energy-related metabolites and energy charge was measured from the vastus lateralis muscle, as was isometric muscle strength of knee extension. Cross-sectional area of the quadriceps femoris muscle was calculated from magnetic resonance imaging. Re...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/(sici)1097-4598(199711)20:11<1341::aid-mus
更新日期:1997-11-01 00:00:00
abstract::Mutations in the myelin protein zero gene (MPZ) are associated with certain demyelinating neuropathies, and in particular with Charcot-Marie-Tooth disease type 1B (CMT1B), Dejerine-Sottas syndrome, and congenital hypomyelination. MPZ mutations affecting the protein's transmembrane domain are generally associated with ...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20034
更新日期:2004-06-01 00:00:00
abstract:INTRODUCTION:Balance impairment contributes to gait dysfunction, falls, and reduced quality of life in adults with Charcot-Marie-Tooth disease (CMT) but has been minimally examined in pediatric CMT. METHODS:The CMT Pediatric Scale (CMTPedS) was administered to 520 children with CMT. Associations between balance functi...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26500
更新日期:2019-09-01 00:00:00
abstract::Loss of cells from the motor system occurs during the normal aging process, leading to reduction in the complement of motor neurons and muscle fibers. The latter age-related decrease in muscle mass has been termed "sarcopenia" and is often combined with the detrimental effects of a sedentary lifestyle in older adults,...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.1215
更新日期:2002-01-01 00:00:00
abstract::Chronic inflammatory demyelinating polyneuropathy (CIDP) presents in rare instances with focal or multifocal upper limb involvement. We reviewed the clinical and electromyographic (EMG) characteristics of 10 such patients (UL-CIDP) and compared them with patients with typical generalized CIDP (G-CIDP) and multifocal m...
journal_title:Muscle & nerve
pub_type: 临床试验,杂志文章
doi:10.1002/(sici)1097-4598(199906)22:6<758::aid-mus13
更新日期:1999-06-01 00:00:00
abstract:INTRODUCTION:We sought to translate, culturally adapt, and assess the Arabic version of the 15-item myasthenia gravis quality-of-life revised scale (MGQOL15R). METHODS:We assessed reliability with Cronbach α; reproducibility with intraclass correlation coefficient (ICC); validity with Spearman correlations for myasthe...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.25948
更新日期:2018-04-01 00:00:00
abstract:INTRODUCTION:Sepsis often causes diaphragm contractile dysfunction. Dihydropyridine receptors (DHPRα1s and DHPRα1c) and ryanodine receptors (RyR1, RyR2, and RyR3) are essential for excitation-contraction coupling in striated muscles. However, their expression in diaphragm during sepsis have not been explored. METHODS:...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.23805
更新日期:2013-11-01 00:00:00
abstract::Several studies have suggested the presence of central nervous system involvement manifesting as cognitive impairment in diseases traditionally confined to the peripheral nervous system. The aim of this review is to highlight the character of clinical, genetic, neurofunctional, cognitive, and psychiatric deficits in n...
journal_title:Muscle & nerve
pub_type: 杂志文章,评审
doi:10.1002/mus.20535
更新日期:2006-07-01 00:00:00
abstract::Daptomycin is a lipopeptide antibiotic with strong bactericidal effects against Gram-positive bacteria and minor side effects on skeletal muscles. The type and magnitude of the early effect of daptomycin on skeletal muscles of rats was quantified by histopathology, examination of contractile properties, Evans Blue Dye...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.21691
更新日期:2010-09-01 00:00:00
abstract::Force fluctuations in leg muscles increase after bedrest, perhaps due to modulation of the neural strategy that is specific to a muscle or common to agonist muscles. The purpose of this study was to examine the modulation of muscle activity and force fluctuations during steady contractions with variable involvement of...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.20764
更新日期:2007-06-01 00:00:00
abstract:INTRODUCTION:Phospholipids are essential components of cellular membranes and are closely associated with cellular functions, but relationships involving skeletal muscle phospholipid profiles and their physiological phenotypes have remained unclear. METHODS:We carried out comprehensive phospholipid analyses using liqu...
journal_title:Muscle & nerve
pub_type: 杂志文章
doi:10.1002/mus.26993
更新日期:2020-09-01 00:00:00