Abstract:
OBJECTIVES:The aim of the study was to evaluate clinical outcome and patterns of disease progression relating to stenosis of the internal carotid artery (ICA) opposite to the operated side, using ultrasonographic risk score of ICA plaques. METHODS:150 patients who underwent ICA endarterectomy for transient ischemic attack (TIA) between January 1997 and December 2000 were studied prospectively. The progress (modified Strandness criteria) and ultrasonographic morphology of ICA plaques on the contralateral side were followed using digitally assisted plaque analysis. Parameters of the plaque image were analyzed and compared with neurologic events. RESULTS:Progression of contralateral stenosis from < 50% to 50-79% occurred in 11/105 patients (10.5%), all asymptomatic; from 50-79% to 80-99% in 10/31 patients (9.5%, one TIA). One patient progressed from the > 50% group to the 80-99% group and remained asymptomatic. After the progression of stenosis there were 32 patients with 50-79% stenosis and 25 with 80-99%. Among those with 50-79% stenosis, two patients developed symptoms (one TIA and one stroke). Among those with 80-99% stenosis, three patients developed symptoms (two TIAs and one stroke). Of the 105 patients who began with an initial contralateral stenosis of <50%, there remained 93; Seven developed symptoms appropriate to the contralateral carotid artery (four TIAs and three strokes). Life-table comparison (Cox's F test) of patients with < 50% stenosis (N = 93) and those with > 50% stenosis (N = 57, groups with > 50% stenosis taken together) showed no important statistical connection (F =1.71, p = 0.378). All plaques were heterogenous and there was no difference in global echogenicity. However, the activity index (AI) in patients with more than 50% stenosis (N=57, groups 50-79% and 80-99% together) was higher than 60 in 19 patients and lower than 60 in 38 patients. There were four neurologic events (three TIAs, one stroke) in the first group (AI > 60) and one neurologic event in the second (one stroke). Life-table comparison (Cox's F test) of the two groups based on the AI showed a significant difference (F=8.84, p=0.001). 18 patients were operated on the contralateral side on the basis of an elevated ultrasonographic AI. There was no morbidity or mortality in the operated group. CONCLUSIONS:Digitally assisted analysis of ultrasonographic ICA plaque morphology is unable to identify high-risk plaques in patients with less than 50% stenosis. In asymptomatic patients with more than 50% stenosis, an ultrasonographic plaque AI higher than 60 may contribute to a more objective selection of patients for operation.
journal_name
Wien Klin Wochenschrjournal_title
Wiener klinische Wochenschriftauthors
Flis V,Miksić K,Tetizkovic Esubject
Has Abstractpub_date
2004-01-01 00:00:00pages
44-50eissn
0043-5325issn
1613-7671journal_volume
116 Suppl 2pub_type
杂志文章abstract::In a prospective phase II study 15 patients suffering from anaplastic thyroid carcinoma or thyroid sarcoma were treated by surgery and chemotherapy. Chemotherapy varied according to age of the patient and histological subtype of the tumour. The following regimen was used: 100 mg/m2 BSA CDDP, 20 mg/m2 mitoxantrone and ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1990-04-27 00:00:00
abstract:BACKGROUND:Heart failure is associated with low-grade inflammation. In the present study we sought to assess the prognostic impact of orosomucoid, a marker of inflammation, in outpatients with heart failure. METHODS:In outpatients with chronic heart failure (no change in clinical status and/or therapy >3 months prior ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-016-1034-5
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Clinical implications of subclinical hypothyroidism (SCH) are still matter of intense debate, resulting in the controversial discussion whether subclinical hypothyroidism should be treated. We performed a cohort study to evaluate the impact of subclinical hypothyroidism on vascular and overall mortality. ME...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-015-0846-z
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:In this study we investigated the neurolinguistic and neuroimaging characteristics of post-stroke motor aphasia patients. The effects of acupuncture on cortex activation by using magnetic resonance imaging (MRI) in patients with motor aphasia were also studied. METHODS:In this study 43 patients with motor a...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章
doi:10.1007/s00508-016-1070-1
更新日期:2017-02-01 00:00:00
abstract::Evidence demonstrates that medical diabetes treatment has to be accompanied by lifestyle modifications. Structured nutrition interventions and increased physical activity will help patients to normalise, respectively maintain their body weight. The main target of a diabetes therapy is aimed at achieving normal or near...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-015-0926-0
更新日期:2016-04-01 00:00:00
abstract:AIM:Sleep disordered breathing (SDB) is an inevitable complication of progressive neuromuscular disorders (NMD). Aim of the study was to prospectively investigate the impact of three months of non-invasive ventilation (NIV) on sleep and SDB-associated symptoms in children and adolescents with advanced NMD. METHODS:Twe...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/BF03040405
更新日期:2003-12-30 00:00:00
abstract:BACKGROUND:Non-syndromic autosomal dominant hearing impairment is characteristically postlingual in onset. Genetic diagnostics are essential for genetic counselling, disease prognosis and understanding of the molecular mechanisms of disease. To date, 36 causative genes have been identified, many in only individual fami...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-017-1230-y
更新日期:2018-05-01 00:00:00
abstract::Bárány's main achievement is that he unified known, but apparently contradictory facts into one perspective. The concept of a method for examining each ear individually by means of the caloric test fundamentally advanced diagnostics. In 1914 he was honoured with the Nobel Prize, but in his home town of Vienna he was d...
journal_title:Wiener klinische Wochenschrift
pub_type: 传,历史文章,杂志文章
doi:
更新日期:1986-09-26 00:00:00
abstract::Active euthanasia, a question of individual existence, fundamentally concerns the concept of human society. Although legalizing voluntary euthanasia seems to be consequent in liberal democracy, delegation of the act of homicide leads to a paradox in liberalism: Generalization in the assessment of individual life--as i...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:2002-11-30 00:00:00
abstract:BACKGROUND:Prolonged pregnancy is the most frequent reason for induction of labor. This study aims to determine the effects of labor induction on delivery outcome and to quantify the risks of cesarean delivery associated with labor induction in post-date pregnancies. PATIENTS AND METHODS:This retrospective case-contro...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-005-0330-2
更新日期:2005-04-01 00:00:00
abstract::With the decline of the former main causes of death in early childhood--infections and starvation--sudden infant death syndrome (SIDS) has emerged as the most important single cause of postneonatal infant mortality. It has adopted the role of a major indicator for the standard of public health care. Despite extensive ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-10 00:00:00
abstract::The extra-anatomic bypass procedure is a well accepted alternative to direct aortoiliac reconstruction in high-risk patients or in cases of local inoperability. Between 1980 and 1987 74 patients (54 men, 20 women; mean age = 71 years, 43 to 90) underwent a total of 78 extra-anatomic reconstructions: 23 axillounifemora...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1989-12-08 00:00:00
abstract::Atherosclerosis is the leading cause of morbidity and mortality in the Western World. Standard imaging techniques such as angiography, ultrasonography and computed tomography are still not effective in detecting atheromatous plaques in their early stages of development, when the lesions are most metabolically active a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::The ambient ozone concentration has increased greatly over the past decades, which may lead to environmental health problems, especially during the summer. WHO guidelines recommend an 8 hour mean value of < or = 60 ppb ozone without health risk. The aim of the present study was to investigate if elevated zone concentr...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1997-05-09 00:00:00
abstract::Four renal transplant recipients, treated with the immunosuppressive combination of azathioprine-prednisolone, developed organ or systemic mycoses caused by Candida albicans and, in one case, additionally by Trichophyton rubrum. Ketoconazole, a new wide-spectrum antimycotic drug, was successfully used in the treatment...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1981-07-10 00:00:00
abstract::The prevalence and significance of cardiac amyloidosis have been considerably underestimated in the past; however, the number of patients diagnosed with cardiac amyloidosis has increased significantly recently due to growing awareness of the disease, improved diagnostic capabilities and demographic trends. Specific th...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-020-01781-z
更新日期:2020-12-01 00:00:00
abstract::Total oesophageal resection for cancer is a major procedure, involving surgery within the thoracic cage, the abdomen and the cervical mediastinum. Plastic restruction using a segment of colon which is placed retrosternally between the cervical oesophagus and the stomach, is an additional procedure of considerable diff...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-09-19 00:00:00
abstract::Primary, secondary and tertiary prevention are usually differentiated. All preventive measures have to prevail against criteria of effectiveness and efficiency. In the case of primary prevention, the search for risk factors is particularly important. The present limits of prevention of back pain are discussed in some ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Hypertension contributes to the inexorable decline of renal function in patients with chronic renal impairment. Studies on the long-term use of converting enzyme inhibitors and calcium antagonists in the treatment of hypertension in patients with chronic renal failure are hereby reviewed. The data demonstrate that con...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1990-05-25 00:00:00
abstract::Pleural effusions are found in 3 to 17% of patients with chronic pancreatitis. The most likely underlying pathogenetic mechanism is transdiaphragmatic lymphatic transfer of pancreatic secretions to the subpleural space, whilst a rare cause is the formation of pancreatico-pleural fistulae. The measurement of amylase ac...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-12-20 00:00:00
abstract::A double-blind trial was carried out in 80 patients, whereby jopamidol, the first stabilized non-ionic contrast medium, and meglumine iodamine were compared in 40 patients undergoing cranial computed tomography and 40 patients subjected to cerebral angiography. There was no difference in the quality of the radiographs...
journal_title:Wiener klinische Wochenschrift
pub_type: 临床试验,杂志文章
doi:
更新日期:1983-01-21 00:00:00
abstract::Gastric epithelioid leiomyosarcoma (epLMS), which generally occurs in mid- or late adult life, is a rare smooth muscle tumor of the stomach. Out of 25 soft tissue tumors of the stomach operated at the Department of Surgery, University of Graz, two epLMS were diagnosed. This paper presents the case of a 67-year-old mal...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract::The "asthma programme", the product of teamwork between the 1st Department of Dermatology and the 2nd Department of Medicine is presented. It contains all examinations necessary for the diagnosis of bronchial asthma: case history, skin test, IgE, RAST, lung function test, inhalative provocation test. The value of each...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1975-11-28 00:00:00
abstract::Dietary fatty acids of the n-6 mainly linoleic acid (LA) series, and of the n-3, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) series both reduce plasma cholesterol levels and platelet responses to aggregating agents. The potency of n-3 fatty acids, which are present in relatively high concentrati...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:
更新日期:1989-04-14 00:00:00
abstract::Intravenous application of bisphosphonates (BP) represents an established therapeutic strategy of tumor-associated bone metastasis and severe hypercalcemia. Patients can develop osteonecrosis of the jaw (ONJ) as a side effect of this therapy. The diagnosis of ONJ is based on three criteria: a) patients have been or ar...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章,评审
doi:10.1007/s00508-008-1002-9
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Unrepaired left to right atrial shunt lesions can cause significant right ventricular (RV) volume overload. The parameter pulmonary to systemic shunt volume ratio (Qp:Qs) has been shown to detect even small differences between left and right ventricular stroke volume; however, four parameters are needed for ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-020-01659-0
更新日期:2020-06-01 00:00:00
abstract::In end stage congestive heart failure activation of a series of compensatory mechanisms increase renal vascular resistance and impair renal function. Prostaglandin E1 is increasingly used in the treatment of severe heart failure for its vasodilating actions. In various experimental settings prostaglandin E analogues a...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1998-07-31 00:00:00
abstract::A report is given on 154 patients subjected to reoperation of the biliary tract, including 19 cases of stricture to complete destruction of the common bile duct. The preoperative findings, indications, methods of operation and late results are described and discussed. ...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1979-04-13 00:00:00
abstract:BACKGROUND:Subclinical hypothyroidism (SH) occurs when serum thyroid stimulating hormone (TSH) concentrations are raised and serum thyroid hormone concentrations are normal. The effect of SH on the proinflammatory adipose cytokine releasing visceral adipose tissue (VAT) is not clear. The aim of this study is to identif...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:10.1007/s00508-015-0865-9
更新日期:2016-08-01 00:00:00
abstract::A report is presented of the course of a case of the myelodysplastic syndrome which transformed after 16 months into Philadelphia chromosome-negative chronic granulocytic leukaemia. Such a transformation into the myeloproliferative syndrome is considered to be a rare event and some views on the mechanism of this metam...
journal_title:Wiener klinische Wochenschrift
pub_type: 杂志文章
doi:
更新日期:1985-03-29 00:00:00