Abstract:
:In a study designed to evaluate the impact of benzodiazepine use on the outcome of behaviour therapy, 91, severe, chronic agoraphobics (46 BDZ users and 45 non-users) were randomly allocated on a double-blind basis to in vivo exposure with low-dose diazepam (ED) or placebo (EP). Drug doses were adjusted on the basis of weekly psychiatric assessments over weeks 1-4. Patients had 8 x 2 hr exposure sessions (weeks 5-12) and were then withdrawn from medication (weeks 13-16). Re-assessments were completed at weeks 4, 12 and 16, and follow-up assessments at approx 20, 46 and 72 weeks. In the analysis of the results, the clinical outcome was evaluated in relation to the therapeutic regime (ED vs EP) and prior BDZ use (users vs non-users). The results showed that the ED group had greater changes in anxiety than the EP group during the drug manipulation phases (anxiety increasing during BDZ withdrawal). There were no group differences in agoraphobic symptoms and no evidence that the outcome of the behavior therapy was significantly affected by concurrent BDZ treatment. There were significant improvements in agoraphobic symptoms over the treatment period, with no evidence for relapse of treatment gains on withdrawal from BDZ, nor for differential responses over the one year follow-up. Initial differences between users and non-users were less marked than expected, although there was a trend for more drop-outs among users across both ED and EP groups.
journal_name
Behav Res Therjournal_title
Behaviour research and therapyauthors
Wardle J,Hayward P,Higgitt A,Stabl M,Blizard R,Gray Jdoi
10.1016/0005-7967(94)90113-9subject
Has Abstractpub_date
1994-02-01 00:00:00pages
203-15issue
2eissn
0005-7967issn
1873-622Xpii
0005-7967(94)90113-9journal_volume
32pub_type
临床试验,杂志文章,随机对照试验abstract::Animal research has shown that anxiety may inhibit pain through the release of endogenous opioids. On the other hand, anxiety is often believed to exacerbate pain in clinical situations, and anxiety reduction has been shown to attenuate the affective component of pain. In the present study phobic anxiety was induced b...
journal_title:Behaviour research and therapy
pub_type: 临床试验,杂志文章
doi:10.1016/s0005-7967(98)00100-4
更新日期:1999-01-01 00:00:00
abstract::It is generally held that anxiety is characterized by an attentional bias for threatening information. In recent years there has been an important debate whether these biases reside at the level of attentional selection (threat detection) or attentional processing after threat detection (attentional disengagement). In...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2010.08.009
更新日期:2010-12-01 00:00:00
abstract::It is not clear if treatments for depression targeting repetitive negative thinking (RNT: rumination, worry and content-independent perseverative thinking) have a specific effect on RNT resulting in better outcomes than treatments that do not specifically target rumination. We conducted a systematic search of PsycINFO...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,meta分析
doi:10.1016/j.brat.2018.04.002
更新日期:2018-07-01 00:00:00
abstract::Results on cardiac awareness in panic disorder are inconsistent. The present study attempted to clarify whether differences in instructions or the inclusion of patients taking antidepressant medication could account for these inconsistencies. 112 patients with panic disorder with agoraphobia were compared to 40 normal...
journal_title:Behaviour research and therapy
pub_type: 临床试验,杂志文章
doi:10.1016/0005-7967(94)e0002-z
更新日期:1995-01-01 00:00:00
abstract::Sudden gains have been linked to improved outcomes in cognitive behaviour therapy for depression. The relationship between sudden gains and outcome is less clear in other treatment modalities, including interpersonal psychotherapy and supportive expressive therapy, which may indicate different mechanisms of change bet...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2014.06.008
更新日期:2014-09-01 00:00:00
abstract::The Phobic Origins Questionnaire (POQ) [Ost, L.-G. & Hugdahl, K. (1981). Acquisition of phobias and anxiety response patterns in clinical patients. Behaviour Research and Therapy, 19, 439-447.] is the most commonly cited instrument for determining the origins of phobic anxiety and data obtained using this instrument s...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,评审
doi:10.1016/s0005-7967(98)00067-9
更新日期:1998-11-01 00:00:00
abstract::The current study investigated whether physical anxiety sensitivity (AS) is associated with selective attentional biases to affective stimuli in children. The dot-probe paradigm was used to examine the deployment of attention towards words pertaining to anxiety symptomatology, socially threatening words, and positive ...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2006.04.001
更新日期:2007-03-01 00:00:00
abstract::OCD patients experience increased feelings of guilt, threat and uncertainty about harm prevention. As to the relation between these phenomena, it was hypothesised that the experience of guilt acts as "information" that increases the sense of threat and decreases the sense that preventive action is effective. We tested...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2007.03.011
更新日期:2007-10-01 00:00:00
abstract::Individual cognitive behaviour therapy for psychosis (CBTp) is a recommended treatment in the acute phase and beyond. However, less is known about the effectiveness of group CBTp in acute care. This mixed methods study explored the implementation and effectiveness of brief group CBTp with inpatients. This prospective ...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2014.12.008
更新日期:2015-02-01 00:00:00
abstract::There is a growing body of empirical support for Rachman's (1994, 2004, 2006) conceptualization of mental contamination. The aim of this study was to tease apart manipulations of imagined physical descriptions (i.e., clean versus dirty), in the context of both morally sound and reprehensible acts (i.e., consensual ver...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2012.03.007
更新日期:2012-06-01 00:00:00
abstract::Attentional bias modification (ABM) is a promising therapeutic tool aimed at changing patterns of attentional selectivity associated with heightened anxiety. A number of studies have successfully implemented ABM using the modified dot-probe task. However others have not achieved the attentional change required to achi...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2014.12.007
更新日期:2015-02-01 00:00:00
abstract::Two studies were conducted to test a dual-process theory of cognitive vulnerability to depression. According to this theory, implicit and explicit cognitive processes have differential effects on depressive reactions to stressful life events. Implicit processes are hypothesized to be critical in determining an individ...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2006.09.003
更新日期:2007-06-01 00:00:00
abstract::Nineteen subjects high in social anxiety and 20 subjects low in social anxiety were asked to give a 5-min speech in front of three audience members. Audience members were trained to provide indicators of positive evaluation (e.g., smiles) and negative evaluation (e.g. frowns) at irregular intervals during the speech. ...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/s0005-7967(98)00016-3
更新日期:1998-03-01 00:00:00
abstract::The thesis of this paper is that failure to recognize the psychological and physiological differences among panic attacks within DSM-IIIR precludes meaningful comparisons and evaluations of research findings, confounds theoretical issues, and impairs the development of more specific, and thereby more effective, progra...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/0005-7967(92)90046-j
更新日期:1992-07-01 00:00:00
abstract::The effects of diazepam was assessed on a number of measures of phobic anxiety. Snake-phobic subjects underwent two sessions on either diazepam or placebo in a crossover design. In addition to a habituation series, a slide with the phobic object was displayed as well as a live snake which subjects were asked to approa...
journal_title:Behaviour research and therapy
pub_type: 临床试验,杂志文章
doi:10.1016/0005-7967(90)90078-w
更新日期:1990-01-01 00:00:00
abstract::Psychotherapists report routinely not practising evidence-based treatments. However, there is little research examining the content of therapy from the patient perspective. This study examined the self-reported treatment experiences of individuals who had been told that they had received cognitive-behavior therapy (CB...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2015.10.009
更新日期:2015-12-01 00:00:00
abstract::Exposure and response prevention (EX/RP) is an evidence-based treatment for obsessive-compulsive disorder (OCD), yet not all patients achieve wellness with EX/RP. The degree to which patients adhere to EX/RP procedures outside of sessions has been found to predict therapy outcomes, including who achieves post-treatmen...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2016.07.010
更新日期:2016-10-01 00:00:00
abstract::Superior learning for fear-relevant stimuli is typically indicated in the laboratory by faster acquisition of fear responses, greater learned fear, and enhanced resistance to extinction. Three experiments investigated the speed, magnitude, and robustness of UK children's (6-10 years; N = 290; 122 boys, 168 girls) vica...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2017.05.002
更新日期:2017-08-01 00:00:00
abstract::The purpose of this paper is to consider the possible origins of an inflated sense of responsibility which occupies an important place in the cognitive theory of obsessive compulsive disorder (Rachman, S. (1993). Obsessions, responsibility, and guilt. Behaviour Research and Therapy, 31, 149-154. Salkovskis, P. M. (198...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,评审
doi:10.1016/s0005-7967(99)00063-7
更新日期:1999-11-01 00:00:00
abstract::Body checking has been conceptualized as a behavioral manifestation of the core overvaluation of eating, shape, and weight concerns underlying eating disorder psychopathology. Cognitive-behavioral theories suggest that body checking behaviors may function to maintain dietary restriction. The current study examined the...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2013.05.004
更新日期:2013-08-01 00:00:00
abstract::The current study examined the effectiveness of a self-directed video-based format of the 1-2-3 Magic parenting program in reducing dysfunctional parenting and child problem behaviors. Eighty-four parents of children aged 2-10 were randomly assigned to either the intervention group (n = 43) or the waitlist control gro...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2015.01.003
更新日期:2015-03-01 00:00:00
abstract::Thought-action fusion (TAF) refers to a set of cognitive biases that are thought to play a role in the development of obsessional phenomena. To measure these biases, R. Shafran, D. S. Thordarson, and S. Rachman (1996; Journal of Anxiety Disorders, 10, 379-391) developed the TAF-scale. They concluded that the TAF-scale...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/s0005-7967(00)00031-0
更新日期:2001-05-01 00:00:00
abstract::Cognitive-behavioral therapy (CBT) is considered first-line treatment for childhood obsessive-compulsive disorder (OCD). Despite CBT's efficacy, too many children and adolescents do not fully respond to treatment, making the identification of predictors of treatment response highly relevant. Executive functions (EF) h...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2017.08.009
更新日期:2017-12-01 00:00:00
abstract::Outpatient medication adherence is a major problem, especially for patients repeatedly hospitalized for psychiatric disorders. This study included 39 such patients who were receiving case management services from a community mental health center. Patients were matched and randomly assigned to receive in a single sessi...
journal_title:Behaviour research and therapy
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0005-7967(98)00036-9
更新日期:1998-09-01 00:00:00
abstract::The phenomenon of non-fearful panic was investigated in a sample of 83 university students who reported histories of unexpected panic attacks. Based on severity ratings of individual panic symptoms, Ss were classified as having panic attacks characterized by No Fear (N = 22), Low Fear (N = 30) or High Fear (N = 31). T...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/0005-7967(93)90098-f
更新日期:1993-05-01 00:00:00
abstract::The last few decades has seen psychological theories of chronic pain dominated by behavioural concepts and particularly, by the operant model as described by Fordyce et al. (1968: Fordyce, W., Fowler, R., & DeLateur, B. (1968) An application of behavior modification technique to a problem of chronic pain. Behaviour Re...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,评审
doi:10.1016/s0005-7967(00)00061-9
更新日期:2001-07-01 00:00:00
abstract:OBJECTIVE:The aims were to predict cognitive therapy (CT) noncompletion and to determine, relative to other putative predictors, the extent to which the patient skills in CT for recurrent major depressive disorder predicted response in a large, two-site trial. METHOD:Among 523 outpatients aged 18e70, exposed to 12e14 ...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,多中心研究
doi:10.1016/j.brat.2013.01.006
更新日期:2013-05-01 00:00:00
abstract::Avoidance behaviors are central to the anxiety disorders and implicated in many other forms of psychopathology, but the reinforcing mechanism of avoidance remains largely elusive. It has been suggested that subjective relief during successful omission of threat may serve as a reinforcer and contribute to the developme...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2019.103526
更新日期:2020-01-01 00:00:00
abstract::Depression is characterized by a large risk of relapse/recurrence. Mindfulness-based cognitive therapy (MBCT) is a recent non-drug psychotherapeutic intervention to prevent future depressive relapse/recurrence in remitted/recovered depressed patients. In this randomized controlled trial, the authors investigated the e...
journal_title:Behaviour research and therapy
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.brat.2010.04.006
更新日期:2010-08-01 00:00:00
abstract::Increased understanding of the nature and role of intrusive imagery has contributed to the development of effective treatment protocols for some anxiety disorders. However, intrusive imagery in severe health anxiety (hypochondriasis) has been comparatively neglected. Hence, the current study investigates the prevalenc...
journal_title:Behaviour research and therapy
pub_type: 杂志文章
doi:10.1016/j.brat.2010.05.008
更新日期:2010-08-01 00:00:00