Abstract:
:Tonic alertness was investigated in Alzheimer patients and normal elderly subjects. Sensitivity and criterion shifts were investigated across 45 min of continuous testing using a high event rate test with very low target probability. Alzheimer patients showed a significant sensitivity decrement over time that was unrelated to dementia severity. These results suggest that tonic alertness is impaired by Alzheimer's disease even in its early stages.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Brazzelli M,Cocchini G,Della Sala S,Spinnler Hdoi
10.1080/01688639408402698subject
Has Abstractpub_date
1994-12-01 00:00:00pages
851-60issue
6eissn
1380-3395issn
1744-411Xjournal_volume
16pub_type
临床试验,杂志文章abstract::The copy condition of the Rey-Osterrieth Complex Figure (ROCF) is sensitive to Alzheimer's disease (AD) pathology, but its neural correlates remain unclear. We used fluorodeoxyglucose positron emission tomography (FDG-PET) to elucidate this association in 77 patients with probable AD. We observed a correlation between...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2012.763113
更新日期:2013-01-01 00:00:00
abstract::Hemisphere lateralization for speech perception was investigated in a Finnish family with specific language impairment. We used dichotic presentations of consonant-vowel (CV) syllables, consisting of the six stop-consonants paired with the vowel /a/, under three different attentional instructions. The dichotic listeni...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.4.457.13868
更新日期:2003-06-01 00:00:00
abstract::Depression and memory difficulties are among the most common complaints voiced by patients with multiple sclerosis (MS). Nevertheless, little is known about how depression might affect patients' perceptions of their memory difficulties. The present investigation was designed to explore this issue. Results supported a ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.26.2.200.28081
更新日期:2004-04-01 00:00:00
abstract::Forty-one patients with putative Alzheimer's Disease (AD) were evaluated to determine the diagnostic utility of a profile of Wechsler Adult Intelligence Scale (WAIS) subtests which has been proposed by Fuld (1984) to identify cholinergic dysfunction. Only nine (21.9%) of these patients had positive Wechsler profiles. ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638708405359
更新日期:1987-04-01 00:00:00
abstract::A sample of 278 men and 353 elderly women who resided in the community received the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) as part of a study of health in mature adult Oklahomans. Females attained significantly higher scores on the Immediate and Delayed Memory and the Language Index...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.25.8.1065.16732
更新日期:2003-12-01 00:00:00
abstract::Eight malingerers (MPs) were identified via significantly below-chance symptom validity testing (SVT) within a sample of 106 consecutive admissions for neuropsychological evaluation. The resulting incidence of 7.5% is seen as a minimal estimate of malingering within the sample. Eight individuals who "passed" SVT but p...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639308402580
更新日期:1993-07-01 00:00:00
abstract::The neuropsychological functioning of adults with Attention Deficit Hyperactivity Disorder (ADHD) was compared to that of healthy controls and individuals with mild psychiatric disorders including attentional complaints. Thirty adults in each group were examined on the Conners' Continuous Performance Test (CPT) and me...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/1380-3395(200002)22:1;1-8;FT115
更新日期:2000-02-01 00:00:00
abstract::Past research has found links among cerebrovascular risk factors (CVRFs), depression, and cognition in older adults. This study investigated how well baseline cerebrovascular burden and depression predicted verbal fluency three and six months later. Participants were 139 medical rehabilitation patients, age 60 and abo...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390590949322
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Impairments in information processing speed are common in multiple sclerosis (MS), with affected individuals demonstrating slower responses and more intraindividual variability (IIV) in their performance on timed tasks. Evidence suggesting that IIV provides novel information about cognitive deficits in MS is...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2014.903898
更新日期:2014-01-01 00:00:00
abstract:UNLABELLED:Dopaminergic dysfunction is a putative mechanism underlying HIV-associated neurocognitive disorders. Dopamine transporter (DAT), brain-derived neurotrophic factor (BDNF), and catechol-O-methyltransferase (COMT) have been specifically implicated. We report analyses examining the main effects of functional pol...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.623118
更新日期:2012-01-01 00:00:00
abstract::The modified Stroop task was presented to 48 patients with a Whiplash Associated Disorder (WAD) and 48 healthy matched controls to investigate possible attentional impairments in relation to state related factors (headache, neck pain, fatigue, tension and state-anxiety). It was expected that performance on the Stroop ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.24.4.471.1042
更新日期:2002-06-01 00:00:00
abstract::Athletes must be able to successfully navigate the soccer pitch or hockey rink to win the game, requiring maximal cognitive resources to successfully compete. Concussions potentially deplete these resources, and the long-term impact of concussions on an individual's goal-directed visually guided behavior continues to ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,评审
doi:10.1080/13803395.2018.1458823
更新日期:2018-12-01 00:00:00
abstract::This study investigated the relationship between cognitive inhibition and set-switching costs in 13 patients with Parkinson's disease (PD) and 16 control subjects using a set-switching task with fully predictable switches. Incongruent colour-words and numerals were presented in either baseline (only colour-words or on...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.24.8.1046.8374
更新日期:2002-12-01 00:00:00
abstract::Cognitive impairment is common among individuals with heart failure (HF), but the exact nature of these impairments remains unclear. The current study examined 140 older adults with heart failure and sought to determine whether there are distinct cognitive profiles using a cluster analytic approach. Results indicated ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2012.663344
更新日期:2012-01-01 00:00:00
abstract::A group of 30 five- to eight-year-old hydrocephalic children was administered a comprehensive battery of neuropsychological tests. As a group, they displayed a pattern of lower PIQ than VIQ. Their performance was within the average range of many neuropsychological tests, but they performed poorly on some measures of c...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639108401075
更新日期:1991-07-01 00:00:00
abstract::Objective methods for determining clinically relevant neurocognitive change are useful for clinicians and researchers, but the utility of such methods requires validation studies in order to assess their accuracy among target populations. We examined the generalizability of regression equations and reliable change ind...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390600920471
更新日期:2007-08-01 00:00:00
abstract::This paper reviews research concerning impairment of memory during the early and late stages of recovery from closed-head injury (CHI). Posttraumatic and retrograde amnesia are discussed, including direct measurement, rate of forgetting and evoked potential correlates. Studies of residual memory deficit in survivors o...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,评审
doi:10.1080/01688639008400960
更新日期:1990-01-01 00:00:00
abstract::What pattern of brain damage could completely obliterate the sense of olfaction in humans? We had an opportunity to address this intriguing question in Patient B., who has extensive bilateral damage to most of the limbic system, including the medial and lateral temporal lobes, orbital frontal cortex, insular cortex, a...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.633897
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Given that little is known about the associations between alcohol use, cognition, and psychiatric symptoms among veterans with a history of mild traumatic brain injury (mTBI), we aimed to (a) characterize how they differ from veteran controls on a measure of problem drinking; (b) investigate whether proble...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2016.1198468
更新日期:2016-12-01 00:00:00
abstract::Less efficient glucose regulation, the ability to metabolize glucose, has been associated with poorer cognitive performances in older individuals not meeting criteria for type 2 diabetes ( Messier, Tsiakas, Gagnon, & Desrochers, 2010 ). Yet, the influence of glucose regulation on attentional functions, which are sensi...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.589372
更新日期:2011-11-01 00:00:00
abstract::The California Verbal Learning Test (CVLT) is a widely used measure of verbal learning and memory; however, there is little empirical evidence about the effects of the administration procedure on the test results. The primary goal of this study was to examine the effect of the semantic cuing condition on subsequent fr...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/1380-3395(200010)22:5;1-9;FT649
更新日期:2000-10-01 00:00:00
abstract::The purpose of this study was to investigate the effect of age on the line bisection test. One hundred and eight normal dextrals of various ages performed a line bisection task with each hand. They were divided into three different age groups of 36 individuals. The old age group bisected lines significantly further to...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639508402443
更新日期:1995-12-01 00:00:00
abstract::Prospective memory (PM), the memory for future intentions, is an essential component of many day-to-day activities. PM accuracy has consistently been found to decline as a function of age and is further impaired in Alzheimer's disease (AD). In the present study, subjective PM failures, PM accuracy, and cost of carryin...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2013.844772
更新日期:2013-01-01 00:00:00
abstract::The present study sought a clearer understanding of spatial memory function consequent to temporal lobe resection, and, in particular, of spatial memory function with respect to two- as well as three-dimensional frames of reference. Relative to a group of 15 control participants, a group of 15 epilepsy patients with r...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390500434359
更新日期:2006-11-01 00:00:00
abstract::The face is probably the single most important visual object. It is the main cue for identifying familiar people and crucial in nonverbal communication. Face recognition can be demonstrated in newborn babies, suggesting that face recognition is to some degree 'hard-wired' in the brain. Also, neurological disease can s...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.21.3.312.917
更新日期:1999-06-01 00:00:00
abstract::This pilot study characterizes memory functioning of 11 men with occupational chronic solvent encephalopathy (CSE). Pattern (PRM) and spatial recognition (SRM), spatial span (SSP), spatial working memory (SWM), and paired associate learning (PAL) from Cambridge Neuropsychological Test Automated Battery were performed ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390500477515
更新日期:2006-11-01 00:00:00
abstract::HIV-seropositive and seronegative control subjects performed a standard paper-and-pencil version and an experimental reaction time version of the Stroop Color-Word Naming Task. Results indicated that both symptomatic and asymptomatic HIV-positive subjects showed an exaggerated Stroop effect compared to controls, but t...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639208402867
更新日期:1992-09-01 00:00:00
abstract::Stroke disrupts motor, sensory, and cognitive systems in survivors. Unlike in physical impairments, assessment of cognitive function is often inadequate, as no standardized procedure to monitor cognitive recovery post stroke exists. We evaluated a number of novel task-orientated tools designed to assess subtle cogniti...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2012.690368
更新日期:2012-01-01 00:00:00
abstract:INTRODUCTION:Reactive oxygen species are involved in the functional changes necessary for synaptic plasticity, memory, and cognitive function. It is far from clear whether the increased excitability, and which forms of neuronal excitability, should be considered a part of the learning process or, rather, cellular manif...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1007118
更新日期:2015-01-01 00:00:00
abstract::The performance of 11 Alzheimer's (DAT) and 8 anomic aphasic stroke patients is contrasted with that of 32 normal elderly subjects on both the Boston Naming Test (BNT) and the Controlled Oral Word Association Test (COW), a letter-category verbal-fluency test. While both tests require phonological processing, only the ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639008401004
更新日期:1990-08-01 00:00:00