Abstract:
:Eleven of twenty-four patients with severe aplastic anemia given marrow grafts from HLA-identical siblings between October 1970 and March 1973 are alive with normal marrow function and continued evidence of engraftment 3-5 yr later. Ten have been leading normal lives with no immunosuppressive or other drug therapy since day 100 postgrafting. One has had chronic graft-versus-host disease of the skin which is now slowly improving with no therapy. He returned to full-time employment in the summer of 1975. The long-term well-being of almost half of our initial patients emphasizes the importance of marrow transplantation for the treatment of severe aplastic anemia.
journal_name
Bloodjournal_title
Bloodauthors
Storb R,Thomas ED,Buckner CD,Clift RA,Fefer A,Fernando LP,Giblett ER,Johnson FL,Neiman PEsubject
Has Abstractpub_date
1976-10-01 00:00:00pages
485-90issue
4eissn
0006-4971issn
1528-0020journal_volume
48pub_type
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