Behavioral evidence of filling-in at the blind spot of the monkey.

Abstract:

:In human subjects, the blind spot is perceptually filled-in by color and brightness from the surrounding visual field. The present behavioral study examined the occurrence of color filling-in at the blind spot in monkeys. First, the location of the blind spot was determined using a monocular saccade task. The blind spots were located on the horizontal meridian at approximately 15-17 deg from the fixation point in the temporal visual field. Then, filling-in at the blind spot was tested by determining if the monkey could discriminate between an annulus presented on the blind spot and a homogeneous disk in the normal visual field. In this task, the monkey was required to make a saccade to a homogeneous disk of the same color and size as an annulus presented simultaneously in the opposite field. Both stimuli were large enough to cover the blind spot and the inner circle of the annulus was confined inside the blind spot. All four monkeys tested performed this task correctly in over 80% of the trials. However, when one eye was covered and the annulus was presented on the blind spot of the uncovered eye, performance deteriorated significantly. To confirm that these results reflected filling-in, one monkey was trained to maintain fixation when two identical homogeneous disks appeared in opposite visual fields. When only one eye was uncovered, and the annulus was presented on the blind spot of the uncovered eye, the monkey maintained fixation in most of the trials. These results show that monkeys were unable to distinguish an annulus from a homogeneous disk when the annulus was presented on the blind spot. This indicates that color filling-in occurs at the blind spot in monkeys and opens possibility to physiological experiments to study the neural mechanisms of filling-in.

journal_name

Vis Neurosci

journal_title

Visual neuroscience

authors

Komatsu H,Murakami I

doi

10.1017/s0952523800006921

subject

Has Abstract

pub_date

1994-11-01 00:00:00

pages

1103-13

issue

6

eissn

0952-5238

issn

1469-8714

pii

S0952523800006921

journal_volume

11

pub_type

杂志文章
  • Development of multibank rod retinae in deep-sea fishes.

    abstract::We studied the development of multibank rod retinae by monitoring the size-related addition of new layers of rod inner and outer segments in four species of deep-sea fishes and found two different growth paradigms. In the mesopelagic Chauliodus sloani, new banks of rod inner and outer segments are added as long as the...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s095252389815304x

    authors: Fröhlich E,Wagner HJ

    更新日期:1998-05-01 00:00:00

  • Linking perception to neural activity as measured by visual evoked potentials.

    abstract::Linking propositions have played an important role in refining our understanding of the relationship between neural activity and perception. Over the last 40 years, visual evoked potentials (VEPs) have been used in many different ways to address questions of the relationship between neural activity and perception. Thi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章,评审

    doi:10.1017/S0952523813000205

    authors: Norcia AM

    更新日期:2013-11-01 00:00:00

  • The fate of the oculomotor system in clinical bilateral anophthalmia.

    abstract::The interdependence of the development of the eye and oculomotor system during embryogenesis is currently unclear. The occurrence of clinical anophthalmia, where the globe fails to develop, permits us to study the effects this has on the development of the complex neuromuscular system controlling eye movements. In thi...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523812000119

    authors: Bridge H,Ragge N,Jenkinson N,Cowey A,Watkins KE

    更新日期:2012-05-01 00:00:00

  • The discoloration illusion.

    abstract::The discoloration illusion, a new visual phenomenon, is described. This phenomenon originates from the juxtaposition of eight chromatic parallel contours on a white background, creating a luminance gradient and enclosing a light red region. Under these conditions, the inner region appears white: the light red discolor...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806233406

    authors: Pinna B

    更新日期:2006-05-01 00:00:00

  • Fixational ocular motor control is plastic despite visual deprivation.

    abstract::The aim of this study was to assess the plasticity of human voluntary fixational eye movement control in relation to visual experience/chronic visual deprivation. Twelve blind adults participated (self-reported vision < or = light perception in each eye; age range = 23-56 years; visual experience range = 0-28 years; b...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523802194090

    authors: Hall EC,Ciuffreda KJ

    更新日期:2002-07-01 00:00:00

  • Effect of early monocular enucleation upon ocular dominance columns and cytochrome oxidase activity in monkey and human visual cortex.

    abstract::We examined cytochrome oxidase (CO) activity in striate cortex of four macaque monkeys after monocular enucleation at ages 1, 1, 5, and 12 weeks. These animal experiments were performed to guide our interpretation of CO patterns in occipital lobe specimens obtained from two children who died several years after monocu...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523898152124

    authors: Horton JC,Hocking DR

    更新日期:1998-03-01 00:00:00

  • Effects of different forms of monocular deprivation on primary visual cortex maps.

    abstract::Monocular deprivation (MD) by lid suture is one of the classic paradigms for the study of developmental plasticity in the cerebral cortex, and we have detailed knowledge of its anatomical and physiological consequences as well as underlying molecular and cellular mechanisms. However, the effects of other forms of mani...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523812000260

    authors: Jaffer S,Vorobyov V,Sengpiel F

    更新日期:2012-09-01 00:00:00

  • Transitions between color categories mapped with a reverse Stroop task.

    abstract::In the reverse Stroop task, observers are instructed to ignore the ink color in which a color word is printed (the distractor color) and to respond to the meaning of the color word (the target). Reaction times (RTs) are faster with congruent combinations when the ink color matches the word than with incongruent combin...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523806233388

    authors: Smithson HE,Khan SS,Sharpe LT,Stockman A

    更新日期:2006-05-01 00:00:00

  • Effect of temporal sparseness and dichoptic presentation on multifocal visual evoked potentials.

    abstract::Multifocal VEP (mfVEP) responses were obtained from 13 normal human subjects for nine test conditions, covering three viewing conditions (dichoptic and left and right monocular), and three different temporal stimulation forms (rapid contrast reversal, rapid pattern pulse presentation, and slow pattern pulse presentati...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523805221053

    authors: James AC,Ruseckaite R,Maddess T

    更新日期:2005-01-01 00:00:00

  • Psychophysical analysis of contrast processing segregated into magnocellular and parvocellular systems in asymptomatic carriers of 11778 Leber's hereditary optic neuropathy.

    abstract::We examined achromatic contrast discrimination in asymptomatic carriers of 11778 Leber's hereditary optic neuropathy (LHON 18 controls) and 18 age-match were also tested. To evaluate magnocellular (MC) and Parvocellular (PC) contrast discrimination, we used a version of Pokorny and Smith's (1997) pulsed/steady-pedesta...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080462

    authors: Gualtieri M,Bandeira M,Hamer RD,Costa MF,Oliveira AG,Moura AL,Sadun F,De Negri AM,Berezovsky A,Salomão SR,Carelli V,Sadun AA,Ventura DF

    更新日期:2008-05-01 00:00:00

  • Synaptic inputs to retrogradely labeled ganglion cells in the retina of the cane toad, Bufo marinus.

    abstract::The entire population of ganglion cells in the retina of the toad Bufo marinus was labeled by retrograde transport of a lysine-fixable biotinylated dextran amine of 3000 molecular weight. Synaptic connections between bipolar, amacrine, and ganglion cells in the inner plexiform layer were quantitatively analyzed, with ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800011792

    authors: Zhu BS,Gibbins IL

    更新日期:1997-11-01 00:00:00

  • Development of the primate area of high acuity, 3: temporal relationships between pit formation, retinal elongation and cone packing.

    abstract::By establishing an avascular, highly elastic, region within the fetal area of high acuity (AHA), the developing primate eye has created a unique substrate on which the mechanical forces of intraocular pressure (IOP) and growth-induced retinal stretch (stretch) can act. We proposed (Springer & Hendrickson, 2004b) that ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S095252380522206X

    authors: Springer AD,Hendrickson AE

    更新日期:2005-03-01 00:00:00

  • AMPA-selective glutamate receptor subunits GluR2 and GluR4 in the cat retina: an immunocytochemical study.

    abstract::AMPA-selective glutamate receptors play a major role in glutamatergic neurotransmission in the retina and are expressed in a variety of neuronal subpopulations. In the present study, immunocytochemical techniques were used to visualize the distribution of GluR2 and GluR4 subunits in the cat retina. Results were compar...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523899166100

    authors: Qin P,Pourcho RG

    更新日期:1999-11-01 00:00:00

  • Visual responsiveness and direction selectivity of cells in area 18 during local reversible inactivation of area 17 in cats.

    abstract::We have investigated the effects of inactivation of localized sites in area 17 on the visual responses of cells in visuotopically corresponding regions of area 18. Experiments were performed on adult normal cats. The striate cortex was inactivated by the injection of nanoliters of lidocaine hydrochloride or of gamma-a...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001826

    authors: Casanova C,Michaud Y,Morin C,McKinley PA,Molotchnikoff S

    更新日期:1992-12-01 00:00:00

  • Pattern-reversal electroretinogram in response to chromatic stimuli: I. Humans.

    abstract::We have studied the steady-state PERG in human subjects in response to red-green plaid patterns modulated either in luminance or in chromaticity or both. By varying the relative luminance of the red and green components, a value could be obtained at which the PERG amplitude was either minimum or locally maximum. This ...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003825

    authors: Morrone C,Porciatti V,Fiorentini A,Burr DC

    更新日期:1994-09-01 00:00:00

  • How many pixels make an image?

    abstract::The human visual system is remarkably tolerant to degradation in image resolution: human performance in scene categorization remains high no matter whether low-resolution images or multimegapixel images are used. This observation raises the question of how many pixels are required to form a meaningful representation o...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080930

    authors: Torralba A

    更新日期:2009-01-01 00:00:00

  • Cell density ratios in a foveal patch in macaque retina.

    abstract::We examine the assumptions that the fovea contains equal numbers of inner (invaginating or ON) and outer (flat or OFF) midget bipolar cells and equal numbers of inner and outer diffuse bipolar cells. Based on reconstruction from electron photomicrographs of serial thin sections through the fovea of a macaque monkey, w...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523803202091

    authors: Ahmad KM,Klug K,Herr S,Sterling P,Schein S

    更新日期:2003-03-01 00:00:00

  • Strain variations in cone wavelength peaks in situ during zebrafish development.

    abstract::There are four cone morphologies in zebrafish, corresponding to UV (U), blue (B), green (G), and red (R)-sensing types; yet genetically, eight cone opsins are expressed. How eight opsins are physiologically siloed in four cone types is not well understood, and in larvae, cone physiological spectral peaks are unstudied...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523819000075

    authors: Nelson RF,Balraj A,Suresh T,Torvund M,Patterson SS

    更新日期:2019-07-30 00:00:00

  • The determination of total cGMP levels in rod outer segments from intact toad photoreceptors in response to light superimposed on background and to consecutive flashes: a second light flash accelerates the dark recovery rate of cGMP levels in control medi

    abstract::In previous experiments we established that a light flash reduced cGMP levels of toad rod outer segments within the transduction time interval, but that recovery of the dark level of cGMP occurred more slowly than reported electrophysiological recovery of membrane potential. We now report that a second light flash acc...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800003230

    authors: Cohen AI,Blazynski C

    更新日期:1993-01-01 00:00:00

  • Reduction of ocular blood flow results in glial fibrillary acidic protein (GFAP) expression in rat retinal Müller cells.

    abstract::Reduction of blood flow to the rat retina was achieved by either clamping both carotid arteries briefly (24 min) or combining clamping of the carotid arteries with permanent occlusion of the vertebral arteries. Analysis of retinas 6 days after operations showed that GFAP immunoreactivity is expressed throughout the re...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800010427

    authors: Osborne NN,Block F,Sontag KH

    更新日期:1991-12-01 00:00:00

  • Visual experience promotes the isotropic representation of orientation preference.

    abstract::Within the visual cortex of several mammalian species, more circuitry is devoted to the representation of vertical and horizontal orientations than oblique orientations. The sensitivity of this representation of orientation preference to visual experience during cortical maturation and the overabundance of cardinal co...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523804041045

    authors: Coppola DM,White LE

    更新日期:2004-01-01 00:00:00

  • The relationship between GABA-containing cells and the cholinergic circuitry in the rabbit retina.

    abstract::As a part of ongoing efforts to understand the cholinergic circuitry in the mammalian retina, we studied the coexpression of nicotinic acetylcholine receptors (nAChRs) and gamma-aminobutyric acid (GABA), the GABA transporter 1 (GAT-1), or choline acetyltransferase (ChAT) immunoreactivity in the rabbit retina. Double-l...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801181083

    authors: Dmitrieva NA,Lindstrom JM,Keyser KT

    更新日期:2001-01-01 00:00:00

  • Morphology and visual pigment content of photoreceptors from injured goldfish retina.

    abstract::Adult teleost fish retinas can regenerate neurons following either surgical or pharmacological injury. The cellular milieu of the damaged retina within which regenerated neurons are produced might be different in these two model systems of retinal injury, and thus the phenotypic attributes of regenerated neurons in th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800174115

    authors: Cameron DA,Powers MK

    更新日期:2000-07-01 00:00:00

  • Movement of retinal along cone and rod photoreceptors.

    abstract::Single isolated photoreceptors can be taken through a visual cycle of light adaptation by bleaching visual pigment, followed by dark adaptation when supplied with 11-cis retinal. Light adaptation after bleaching is manifested by faster response kinetics and a permanent reduction in sensitivity to light flashes, presum...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800001735

    authors: Jin J,Jones GJ,Cornwall MC

    更新日期:1994-03-01 00:00:00

  • Wide-field cone bipolar cells and the blue-ON pathway to color-coded ganglion cells in rabbit retina.

    abstract::Wide-field cone bipolar cells with sparse dendritic branching and proposed connectivity to blue cones were first identified in rabbit and cat. In rabbit, these were subdivided into type a (wa) and type b (wb), with axonal branching in sublamina a, and sublamina b, respectively, of the inner plexiform layer (IPL). Rece...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523808080061

    authors: Famiglietti EV

    更新日期:2008-01-01 00:00:00

  • Photoreceptors and visual pigments in the red-eared turtle, Trachemys scripta elegans.

    abstract::Absorbance spectra of cone outer segments and oil droplets were recorded microspectrophotometrically in the retina of the red-eared turtle, Trachemys scripta elegans. There are four cone visual pigments, with lambda(max) = 617 nm (red sensitive), 515 nm (green sensitive), 458 nm (blue sensitive), and 372 nm (UV-sensit...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523801185081

    authors: Loew ER,Govardovskii VI

    更新日期:2001-09-01 00:00:00

  • Visual callosal projections in the adult ferret.

    abstract::The laminar and tangential organization of visual callosal projections of areas 17 and 18 were investigated in the adult ferret, using histochemical methods to visualize axonally transported horseradish peroxidase (HRP). Normal adult ferrets were given injections of HRP throughout one visual cortex or had gelfoam soak...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800006398

    authors: Grigonis AM,Rayos del Sol-Padua RB,Murphy EH

    更新日期:1992-07-01 00:00:00

  • Development of excitatory and inhibitory neurotransmitters in transitory cholinergic neurons, starburst amacrine cells, and GABAergic amacrine cells of rabbit retina, with implications for previsual and visual development of retinal ganglion cells.

    abstract::Starburst amacrine cells (SACs), the only acetylcholine (ACh)-releasing amacrine cells (ACs) in adult rabbit retina, contain GABA and are key elements in the retina's directionally selective (DS) mechanism. Unlike many other GABAergic ACs, they use glutamic acid decarboxlyase (GAD)(67), not GAD(65), to synthesize GABA...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523810000052

    authors: Famiglietti EV,Sundquist SJ

    更新日期:2010-03-01 00:00:00

  • N-type and L-type calcium channels mediate glycinergic synaptic inputs to retinal ganglion cells of tiger salamanders.

    abstract::Synaptically localized calcium channels shape the timecourse of synaptic release, are a prominent site for neuromodulation, and have been implicated in genetic disease. In retina, it is well established that L-type calcium channels play a major role in mediating release of glutamate from the photoreceptors and bipolar...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/S0952523804214055

    authors: Bieda MC,Copenhagen DR

    更新日期:2004-07-01 00:00:00

  • Agrin mRNA expression in the developing chick Edinger-Westphal nucleus.

    abstract::Agrin is a large extracellular matrix protein that directs the accumulation of acetylcholine receptors at the neuromuscular junction. Recent evidence suggests that agrin may be involved in organizing synapses in the visual system as well. Focussing on the pathway that controls accommodation and pupilloconstriction, th...

    journal_title:Visual neuroscience

    pub_type: 杂志文章

    doi:10.1017/s0952523800007537

    authors: McAvoy M,Smith MA,Fujii JT

    更新日期:1996-03-01 00:00:00