Dosimetric characteristics of the Leipzig surface applicators used in the high dose rate brachy radiotherapy.

Abstract:

:The nucletron Leipzig applicator is designed for (HDR) 192Ir brachy radiotherapy of surface lesions. The dosimetric characteristics of this applicator were investigated using simulation method based on Monte Carlo N-particle (MCNP) code and phantom measurements. The simulation method was validated by comparing calculated dose rate distributions of nucletron microSelectron HDR 192Ir source against published data. Radiochromic films and metal-oxide-semiconductor field-effect transistor (MOSFET) detectors were used for phantom measurements. The double exposure technique, correcting the nonuniform film sensitivity, was applied in the film dosimetry. The linear fit of multiple readings with different irradiation times performed for each MOSFET detector measurement was used to obtain the dose rate of each measurement and to correct the source transit-time error. The film and MOSFET measurements have uncertainties of 3%-7% and 3%-5%, respectively. The dose rate distributions of the Leipzig applicator with 30 mm opening calculated by the validated MC method were verified by measurements of film and MOSFET detectors. Calculated two-dimensional planar dose rate distributions show similar patterns as the film measurement. MC calculated dose rate at a reference point defined at depth 5 mm on the applicator's central axis is 7% lower than the film and 3% higher than the MOSFET measurements. The dose rate of a Leipzig applicator with 30 mm opening at reference point is 0.241+/-3% cGy h(-1) U(-1). The MC calculated depth dose rates and profiles were tabulated for clinic use.

journal_name

Med Phys

journal_title

Medical physics

authors

Niu H,Hsi WC,Chu JC,Kirk MC,Kouwenhoven E

doi

10.1118/1.1812609

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

3372-7

issue

12

eissn

0094-2405

issn

2473-4209

journal_volume

31

pub_type

杂志文章
  • SU-E-I-16: Automated Liver Segmentation Method for CBCT Dataset by Probabilistic Atlas Construction.

    abstract:PURPOSE:The aiming is getting accurate liver contour structures automatically for following adaptive radiation therapy in daily CBCT images which is very low-contrast comparing the planning CT. METHODS:Probabilistic atlas is constructed by 50 intravenous contrast planning CT images by iterative affine registration pro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4734730

    authors: Li D,Li H,Yin Y,Chen J

    更新日期:2012-06-01 00:00:00

  • Validation of reconstructed bremsstrahlung spectra between 6 MV and 25 MV from measured transmission data.

    abstract::We have previously investigated a method of high-energy x-ray spectral reconstruction from transmission data by direct resolution of a matrix system. This technique uses the spectral vectorial algebra formalism. The resolution has previously been tested on a 12 MV photon beam. To extend and to test the validity of the...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597998

    authors: Francois P,Coste F,Bonnet J,Caselles O

    更新日期:1997-05-01 00:00:00

  • Efficient low-dose CT artifact mitigation using an artifact-matched prior scan.

    abstract:PURPOSE:Low-dose CT has attracted increasing attention due to growing concerns about radiation exposure in medical scans. However, the frugal use of x-ray radiation inevitably reduces the quality of the CT images, introducing artifacts such as noise and streaks which make the reconstructed images difficult to read in c...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4736528

    authors: Xu W,Mueller K

    更新日期:2012-08-01 00:00:00

  • Investigation of three radiation detectors for accurate measurement of absorbed dose in nonstandard fields.

    abstract:PURPOSE:To establish accurate experimental dosimetry techniques for reference dose measurements in nonstandard composite fields. METHODS:A cylindrical PMMA phantom filled with water was constructed, at the center of which reference absorbed dose to water for a head and neck IMRT delivery was measured. Based on the pro...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3392247

    authors: Chung E,Bouchard H,Seuntjens J

    更新日期:2010-06-01 00:00:00

  • SU-E-T-424: Inter-Fraction Variation of High Dose Regions of OARS in MR Image Based Cervix Brachytherapy Using Rigid Registration.

    abstract:PURPOSE:To quantify the inter fraction variation of spatial location of high dose regions of OARs in MR-image based cervix brachytherapy using rigid registration algorithm. METHODS:Retrospective analysis of 27 previously treated patients under EMBRACE multi-centric trial was evaluated. Each patient had two application...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735513

    authors: Swamidas J,Mahantshetty U,Deshpande D,Shrivastava S

    更新日期:2012-06-01 00:00:00

  • Impact of flat panel-imager veiling glare on scatter-estimation accuracy and image quality of a commercial on-board cone-beam CT imaging system.

    abstract:PURPOSE:The purposes of this study is to measure the low frequency drop (LFD) of the modulation transfer function (MTF), associated with the long tails of the detector point spread function (PSF) of an on-board flat panel imager and study its impact on cone-beam CT (CBCT) image quality and scatter measurement accuracy....

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4747260

    authors: Lazos D,Williamson JF

    更新日期:2012-09-01 00:00:00

  • Mixed model phase evolution for correction of magnetic field inhomogeneity effects in 3D quantitative gradient echo-based MRI.

    abstract:PURPOSE:In 3D gradient echo magnetic resonance imaging (MRI), strong field gradients B0macro are visually observed at air/tissue interfaces. At low spatial resolution in particular, the respective field gradients lead to an apparent increase in intravoxel dephasing, and subsequently, to signal loss or inaccurate R2* es...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.12318

    authors: Fatnassi C,Boucenna R,Zaidi H

    更新日期:2017-07-01 00:00:00

  • "Battered data"--some clinical effects of the abuse of multiple regression methods: the NSD.

    abstract::The NSD equation, D = 1850 x T0.11 x N0.24, is a celebrated transmogrification of Cohen's two well-known collations of data on response to clinical irradiations (3 degrees erythema and 0.90 ablation of skin cancer) in which the relation of D and T is fixed by the data selected by Cohen and the additional constraint th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595034

    authors: Herbert DE Jr

    更新日期:1981-11-01 00:00:00

  • Clinical evaluation of a commercial orthopedic metal artifact reduction tool for CT simulations in radiation therapy.

    abstract:PURPOSE:Severe artifacts in kilovoltage-CT simulation images caused by large metallic implants can significantly degrade the conspicuity and apparent CT Hounsfield number of targets and anatomic structures, jeopardize the confidence of anatomical segmentation, and introduce inaccuracies into the radiation therapy treat...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4762814

    authors: Li H,Noel C,Chen H,Harold Li H,Low D,Moore K,Klahr P,Michalski J,Gay HA,Thorstad W,Mutic S

    更新日期:2012-12-01 00:00:00

  • An automated dosimetry data-acquisition and analysis system at the LAMPF pion therapy facility.

    abstract::An automated data-acquisition and analysis system has been developed for dosimetry measurements on the pion therapy beam at the Clinton P. Anderson Meson Physics Facility Biomedical Channel in Los Alamos using a PDP-11/45 computer and CAMAC interface. Initialization, test, and monitor programs allow the user to set th...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594418

    authors: Rosen I,Smith A,Lane R,Kelsey C,Lake D,Hogstrom K,Somers J,Helland J,Kittell R,Amols H,Bradbury J,Richman C

    更新日期:1978-03-01 00:00:00

  • Depth dose characteristics of 24-MV x-ray beams at extended SSD.

    abstract::Depth dose characteristics of 24-MV beams from a medical linear accelerator at various SSDs have been measured. The dose buildup, percent depth dose (PDD), and output were measured using ionization chambers and a diode detector under full scatter. Surface dose ranged from 8% to 51% depending upon the collimator settin...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.596673

    authors: Jani SK,Pennington EC

    更新日期:1991-03-01 00:00:00

  • Thermal regulation of tightly packed solid-state photodetectors in a 1 mm(3) resolution clinical PET system.

    abstract:PURPOSE:Silicon photodetectors are of significant interest for use in positron emission tomography (PET) systems due to their compact size, insensitivity to magnetic fields, and high quantum efficiency. However, one of their main disadvantages is fluctuations in temperature cause strong shifts in gain of the devices. P...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4903889

    authors: Freese DL,Vandenbroucke A,Innes D,Lau FW,Hsu DF,Reynolds PD,Levin CS

    更新日期:2015-01-01 00:00:00

  • Sci-Thur PM: YIS - 08: The effect of copper conversion plates on low-Z target image quality.

    abstract::Current generation electronic portal imaging devices (EPID) contain a 1.0 mm copper conversion plate to increase detection efficiency of a therapeutic megavoltage spectrum. When using these EPIDs for low-Z target imaging, the conversion plate largely attenuates the large populations of diagnostic energy photons, there...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4740105

    authors: Parsons D,Robar JL

    更新日期:2012-07-01 00:00:00

  • The use of a diode matrix in commissioning activities for electron energies > or = 9 MeV: a feasibility study.

    abstract::The contribution of a commercially available diode matrix (MapCHECK, provided by Sun Nuclear, Melbourne, FL) for the commissioning procedures of the voxel based Monte Carlo (VMC++) algorithm for electron beams of MasterPlan treatment planning system was investigated. The attention is mainly focused on the calculation ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3081414

    authors: Borca VC,Pasquino M,Ozzello F,Tofani S

    更新日期:2009-04-01 00:00:00

  • Absorbed-dose beam quality conversion factors for cylindrical chambers in high energy photon beams.

    abstract::Recent working groups of the AAPM [Almond et al., Med. Phys. 26, 1847 (1999)] and the IAEA (Andreo et al., Draft V.7 of "An International Code of Practice for Dosimetry based on Standards of Absorbed Dose to Water," IAEA, 2000) have described guidelines to base reference dosimetry of high energy photon beams on absorb...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.1328081

    authors: Seuntjens JP,Ross CK,Shortt KR,Rogers DW

    更新日期:2000-12-01 00:00:00

  • SU-E-T-302: A Simulation Study with Geant4 Investigating the Secondary Prompt Gamma Emissions from Incident 40 MeV Protons Onto Various Materials.

    abstract:PURPOSE:This study aims to investigate the prompt secondary gamma spectrum and thedepth-dose distributions of incident 40 MeV protons onto various phantom materials.The goal is to find a relationship between the secondary prompt gamma emissions andthe range of the incident particles. METHODS:An application was constru...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735388

    authors: Lau A,Chen Y,Ahmad S

    更新日期:2012-06-01 00:00:00

  • A system for intensity modulated dose plan verification based on an experimental pencil beam kernel obtained by deconvolution.

    abstract::The number of intensity modulated radiation therapy (IMRT) procedures is continuously growing worldwide and it is necessary to develop tools for patient specific quality assurance (QA) that avoid using machine time that could be employed in treating additional patients. One way of achieving this goal is to perform a m...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2815359

    authors: Azcona JD,Burguete J

    更新日期:2008-01-01 00:00:00

  • Accurate measurement of characteristic curves of II-TV digital systems by use of aluminum stepwedge technique.

    abstract::In order to determine accurately the relative x-ray intensities transmitted through the different steps of an aluminum stepwedge and incident on an image intensifier (II)-TV digital system, we used a 100-mm camera which was attached to the II output. The characteristic curves of an II-TV digital system, which relate t...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.595819

    authors: Fujita H,Doi K

    更新日期:1986-11-01 00:00:00

  • Measurement of primary bremsstrahlung spectrum from an 8-MeV linear accelerator.

    abstract::The bremsstrahlung spectrum from an 8-MeV linear accelerator has been measured using a NaI(T1) spectrometer system. The spectrum shows a low-energy cutoff at 0.4 MeV and the maximum photon energy to be approximately 6% greater than the nominal energy. The maximum emission of energy fluence was 1.6 and 1.8 MeV for meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594221

    authors: Levy LB,Waggener RG,Wright AE

    更新日期:1976-05-01 00:00:00

  • A novel total variation based ring artifact suppression method for CBCT imaging with two-dimensional antiscatter grids.

    abstract:PURPOSE:Two-dimensional antiscatter grids (2DASG) for cone beam computed tomography (CBCT) is a new area of research to reduce scatter intensity, and consequently improve CBCT image quality. One of the challenges in implementation of 2DASGs is their septa shadows that are impinged on the projections. If these artifacts...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1002/mp.13456

    authors: Alexeev T,Kavanagh B,Miften M,Altunbas C

    更新日期:2019-05-01 00:00:00

  • Spectrally resolved bioluminescence tomography using the reciprocity approach.

    abstract::Spectrally resolved bioluminescence optical tomography is an approach to recover images of, for example, Luciferase activity within a volume using multiwavelength emission data from internal bioluminescence sources. The underlying problem of uniqueness associated with nonspectrally resolved intensity-based bioluminesc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.2982138

    authors: Dehghani H,Davis SC,Pogue BW

    更新日期:2008-11-01 00:00:00

  • Position detection accuracy of a novel linac-mounted intrafractional x-ray imaging system.

    abstract:PURPOSE:The authors have developed a system that monitors intrafractional target motion perpendicular to the treatment beam with the aid of radioopaque markers by means of separating kV image and megavoltage (MV) treatment field on a single flat-panel detector. METHODS:They equipped a research Siemens Artiste linear a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.3665712

    authors: Fast MF,Krauss A,Oelfke U,Nill S

    更新日期:2012-01-01 00:00:00

  • A novel approach to evaluate spatial resolution of MRI clinical images for optimization and standardization of breast screening protocols.

    abstract:PURPOSE:Stringent quality assurance is required in MRI breast screening to ensure that different scanners and imaging protocols reach similar diagnostic performance. The authors propose a methodology, based on power spectrum analysis (PSA), to evaluate spatial resolution in clinical images. To demonstrate this approach...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4966704

    authors: Borri M,Scurr ED,Richardson C,Usher M,Leach MO,Schmidt MA

    更新日期:2016-12-01 00:00:00

  • Improved modeling of multiple scattering in the Voxel Monte Carlo model.

    abstract::The implementation of an improved model for multiple scattering into the-Voxel Monte Carlo (VMC) algorithm for fast electron dose calculation in radiation therapy is presented. The model takes into account path-length corrections (PLC) and lateral displacement in the individual electron steps. The extraction of the sc...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.597933

    authors: Kawrakow I

    更新日期:1997-04-01 00:00:00

  • Technical Note: exploring the limit for the conversion of energy-subtracted CT number to electron density for high-atomic-number materials.

    abstract:PURPOSE:For accurate tissue inhomogeneity correction in radiotherapy treatment planning, the authors had previously proposed a novel conversion of the energy-subtracted CT number to an electron density (ΔHU-ρe conversion), which provides a single linear relationship between ΔHU and ρe over a wide ρe range. The purpose ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4881327

    authors: Saito M,Tsukihara M

    更新日期:2014-07-01 00:00:00

  • Effect of lateral boundaries on contrast functions in time-resolved transillumination measurements.

    abstract::The method of images is employed to insert the effects of the presence of a single lateral boundary on contrast functions previously derived for an infinite slab using a random walk model of photon transport. The predictions of the model for zero and extrapolated boundary conditions are compared with Monte Carlo (MC) ...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.598687

    authors: Chernomordik V,Gandjbakhche AH,Hebden JC,Zaccanti G

    更新日期:1999-09-01 00:00:00

  • Patient motion effects on the quantification of regional myocardial blood flow with dynamic PET imaging.

    abstract:PURPOSE:Patient motion is a common problem during dynamic positron emission tomography (PET) scans for quantification of myocardial blood flow (MBF). The purpose of this study was to quantify the prevalence of body motion in a clinical setting and evaluate with realistic phantoms the effects of motion on blood flow qua...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4943565

    authors: Hunter CR,Klein R,Beanlands RS,deKemp RA

    更新日期:2016-04-01 00:00:00

  • SU-F-BRCD-06: Multiple Anatomy Optimization of Accumulated Dose.

    abstract:PURPOSE:Multiple anatomy optimization (MAO) utilizing deformable dose accumulation on entire 4DCT data sets is implemented to overcome ambiguity between optimal dose defined on a single anatomy and optimal accumulated dose resulting from dose delivery to moving and deforming anatomy. METHODS:Six lung cancer patients a...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4735744

    authors: Watkins WT,Moore JA,Sharma M,Dial C,Xu H,Hugo GD,Gordon JJ,Siebers JV

    更新日期:2012-06-01 00:00:00

  • Off-axis beam quality change in linear accelerator x-ray beams.

    abstract::The effective energy of the x-ray beam from linear accelerators changes as a function of the position in the beam due to nonuniform filtration by the flattening filter. In this work, the transmittance through a water column was measured in good geometry and the beam quality characterized in units of HVL in water. Meas...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.594677

    authors: Hanson WF,Berkley LW,Peterson M

    更新日期:1980-03-01 00:00:00

  • Comparison of Gafchromic EBT2 and EBT3 films for clinical photon and proton beams.

    abstract:PURPOSE:Dose verification in highly conformal radiation therapy such as IMRT or proton therapy can benefit from the high spatial resolution offered by radio-chromic films such as Gafchromic EBT or EBT2. Recently, a new generation of these films, EBT3, has become available. The composition and thickness of the sensitive...

    journal_title:Medical physics

    pub_type: 杂志文章

    doi:10.1118/1.4737890

    authors: Reinhardt S,Hillbrand M,Wilkens JJ,Assmann W

    更新日期:2012-08-01 00:00:00