Abstract：
:Respiratory syncytial virus is a common cause of acute respiratory infection in children. Previous reports have associated respiratory syncytial virus infection and acute neurologic symptoms, including apnea and seizures. This study examined the prevalence of acute neurologic symptoms associated with respiratory syncytial virus and non-respiratory syncytial virus respiratory infections in children requiring admission to a pediatric intensive care unit. We screened all admissions over a 4-year period at a single center, identifying children between birth and 2 years of age with bronchiolitis or acute upper respiratory infection. Children with a history of prematurity, preexisting medical conditions, or prior neurologic problems were excluded. Retrospective chart review of 236 admissions was conducted, identifying the etiology of respiratory infection and the presence or absence of acute neurologic signs or symptoms. This study demonstrated a prevalence of acute neurologic signs or symptoms in 36.4% of respiratory syncytial virus-negative patients (n = 115) and 39.1% in the respiratory syncytial virus-positive group (n = 121). Apnea, the most common symptom, was observed in 19.8% of respiratory syncytial virus-positive cases and 16.5% of negative patients. Seizures were reported in 6.6% of the positive cases and in 12.2% of the negative cohort. These differences showed no statistical significance. Although neurologic signs and symptoms are common in this population of children with acute respiratory infection, there was no significant difference in the prevalence of neurologic problems between respiratory syncytial virus-positive and -negative patients.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Kho N,Kerrigan JF,Tong T,Browne R,Knilans Jdoi
10.1177/08830738040190110301subject
Has Abstractpub_date
2004-11-01 00:00:00pages
859-64issue
11eissn
0883-0738issn
1708-8283journal_volume
19pub_type
杂志文章abstract：:Mutations in the STE20-related kinase adaptor α ( STRADA) gene have been reported to cause an autosomal recessive neurodevelopmental disorder characterized by infantile-onset epilepsy, developmental delay, and craniofacial dysmorphisms. To date, there have been 17 reported individuals diagnosed with STRADA mutations, ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073818802724
更新日期：2018-12-01 00:00:00
abstract：:Homozygosity for the methylenetetrahydrofolate reductase (MTHFR) 677C>T mutation (MTHFR TT) has been linked to an increased risk for stroke, coronary artery disease, and migraine headaches. The authors analyzed the potential link between MTHFR 677C>T homozygosity and childhood stroke. A true association might facilita...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073810381446
更新日期：2011-03-01 00:00:00
abstract：:The potential benefits of functional magnetic resonance imaging (MRI) for the investigation of normal development have been limited by difficulties in its use with children. We describe the practical aspects, including failure rates, involved in conducting large-scale functional MRI studies with normal children. Two h...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738020170122201
更新日期：2002-12-01 00:00:00
abstract：:This population-based cross-sectional study evaluates the clinical value of electroretinography and visual evoked potentials in childhood brain tumor survivors. A flash electroretinography and a checkerboard reversal pattern visual evoked potential (or alternatively a flash visual evoked potential) were done for 51 su...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073816634863
更新日期：2016-07-01 00:00:00
abstract：:The etiology of mild mental retardation remains undefined in about 60% of cases. Even though the causes of mild mental retardation are likely to be heterogeneous, the evidence for genetic involvement is increasing, along with the development of specific diagnostic techniques. To improve our understanding of the geneti...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738060210091201
更新日期：2006-09-01 00:00:00
abstract：:Despite remarkable growth in the clinical neurology literature, there is little research on peer review and biomedical publication in neurology. Biomedical publication research encompasses every step of the research process, from the methodology to the publication of research findings. Some general medical journals ha...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/0883073810374647
更新日期：2010-10-01 00:00:00
abstract：:Diagnostic ultrasound has been extensively used for neurologic evaluation of cranial, vascular and spinal diseases. This study presents the techniques, methodology, and procedures for a new diagnostic application of ultrasound for evaluation of the neuromuscular system. In order to determine the optimum sonographic ch...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307388800300115
更新日期：1988-01-01 00:00:00
abstract：:Acute transverse myelitis is a clinical syndrome affecting the spinal cord, which is characterized by acute onset of motor, sensory, and autonomic dysfunction. Approximately 20% of cases of acute transverse myelitis occur in children. This review summarizes the current published literature on acute transverse myelitis...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：10.1177/0883073812452916
更新日期：2012-11-01 00:00:00
abstract：:Our current purpose is to evaluate the applicability of dynamic statistical parametric mapping, a novel method for localizing epileptiform activity recorded with magnetoencephalography in patients with epilepsy. We report four pediatric patients with focal epilepsies. Magnetoencephalographic data were collected with a...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738050200041601
更新日期：2005-04-01 00:00:00
abstract：:Alexander disease is a leukodystrophy caused by dominant missense mutations in the gene encoding the glial fibrillary acidic protein. Individuals with this disorder often present with a typical neuroradiologic pattern including white matter abnormalities with brainstem involvement, selective contrast enhancement, and ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073816673263
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:We present the diagnostic and clinical course of the first multicenter case series of pediatric patients with autoimmune encephalitis associated with N-type voltage-gated calcium channel antibodies. METHODS:Data from 2 university hospitals were retrospectively reviewed and records of 3 patients with autoimmu...
journal_title：Journal of child neurology
pub_type： 杂志文章,多中心研究
doi：10.1177/0883073819840448
更新日期：2019-08-01 00:00:00
abstract：:Corpus callosum agenesis, retardation, adducted thumbs, spastic paraparesis, and hydrocephalus (CRASH syndrome) is an X-linked recessive disorder caused by mutations in the neuronal cell adhesion molecule L1 (LICAM) gene. L1 plays a key role in axon outgrowth and pathfinding during the development of the nervous syste...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307380001500407
更新日期：2000-04-01 00:00:00
abstract：:Assessment of upper limb function, kinematic analysis, and dystonia in patients with spastic diplegia cerebral palsy and periventricular leukomalacia. Seven children with spastic diplegia cerebral palsy and 8 controls underwent upper limb kinematics. Movement duration, average and maximum linear velocity, index of cur...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073817722451
更新日期：2017-10-01 00:00:00
abstract：:Cavernous haemangiomas, or cavernous malformations, have been reported during pregnancy, most of which have been either supratentorial or spinal lesions. We encountered a 15-year old pregnant patient with a rapidly progressive and haemorrhagic brainstem cavernous haemangioma. The case presented here describes the hist...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073812457459
更新日期：2013-10-01 00:00:00
abstract：:Using a questionnaire-based study, we assessed the parent-reported prevalence of attention-deficit hyperactivity disorders (ADHDs), autism spectrum disorders, and obsessive-compulsive disorders in a group of 351 males with Duchenne muscular dystrophy. Of the 351 males with Duchenne muscular dystrophy, 11.7% were repor...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073807309775
更新日期：2008-05-01 00:00:00
abstract：:Homocystinuria represents a group of hereditary metabolic disorders characterized by an accumulation of homocysteine in the serum and an increased excretion of homocysteine in the urine. The infantile form is severe: the main clinical findings are neurologic signs, associated with hematological signs and bone alterati...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809336877
更新日期：2010-03-01 00:00:00
abstract：:We report a divergent ependymal tumor of the posterior fossa (ependymoblastoma/anaplastic ependymoma) observed in an 8-year-old boy. The tumor showed the histological pattern typical of an ependymoblastoma (tubular-papillary fetaloid architecture with stratification of the tumor cells) next to areas in which findings ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073808314160
更新日期：2008-09-01 00:00:00
abstract：:Baclofen is widely used to control spasticity in children with cerebral palsy. Several publications described clinical adverse effects of baclofen oral treatment, but the effect of baclofen on seizure potentiation is still controversial. We describe a 10-year-old female patient with cerebral palsy, epilepsy, and menta...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809357243
更新日期：2010-10-01 00:00:00
abstract：OBJECTIVE:To evaluate the safety and tolerability of adjunctive eslicarbazepine acetate (ESL) in pediatric patients (aged 4-17 years) with refractory focal seizures. METHODS:Pooled safety data from patients aged 4-17 years in Study 208 (NCT01527513) and Study 305 (NCT00988156) were analyzed. Both were randomized, doub...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073819890997
更新日期：2020-03-01 00:00:00
abstract：:The geographic distribution of multiple sclerosis (MS) may relate to the age of initial exposure and degree of sensitization to common viruses or bacteria which have proteins with epitopes (antigenic determinants) which are homologous with potentially encephalitogenic peptides in central myelin proteins, such as basic...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307388700200418
更新日期：1987-10-01 00:00:00
abstract：:The objective of this study was to determine the role of cerebral nitric oxide and its powerful oxidant peroxynitrite following mild birth asphyxia. The cerebrospinal fluid levels of nitric oxide and 3-nitrotyrosine as a marker for peroxynitrite are measured in neonates with mild hypoxic-ischemic encephalopathy. Based...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/08830738020170111101
更新日期：2002-11-01 00:00:00
abstract：:Multiple risk factors contribute to cognitive impairment in children with β-thalassemia major. For a more refined understanding of this issue, we attempted to evaluate cognitive function in β-thalassemia major patients and identify the relationship between possible cognitive dysfunction and the following: demography, ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073814550827
更新日期：2015-03-01 00:00:00
abstract：:The purpose of this study was to determine which clinical characteristics correlated with abnormal computed tomographic (CT) scans in epileptic children. Thirty variables were examined. Of these, four variables (presence of inherited or congenital disease, focal motor findings, developmental delay, and early onset of ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307388600100210
更新日期：1986-04-01 00:00:00
abstract：:Paramyotonia congenita in 22 members of Arab (Omani) family is reported. Four generations were affected. All had early onset around 1 year of age, with myotonia and cold intolerance. Age of onset in the index case was at 3 months of age. Six members with the disease were examined and investigated. To our knowledge, th...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073808330185
更新日期：2010-02-01 00:00:00
abstract：:Little is known about psychiatric aspects of pediatric demyelinating conditions. A total of 23 youths (6-17 years) with demyelinating conditions underwent semistructured psychiatric interviews using the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version. Adolescents...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809338519
更新日期：2010-02-01 00:00:00
abstract：:The first case of Chikungunya virus in Honduras was identified in 2014. The virus has spread widely across Honduras via the Aedes aegypti mosquito, leading to an outbreak of Chikungunya virus (CHIKV) in 2015 that significantly impacted children. A retrospective chart review of 235 children diagnosed with CHIKV and adm...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073817701879
更新日期：2017-07-01 00:00:00
abstract：:Cerebral vasculitis and clinically important myocardial inflammation are rare in juvenile dermatomyositis. We report a previously healthy 6-year-old girl with dermatomyositis who died after a fulminating clinical deterioration. Postmortem examination of the heart revealed characteristic endothelial tubuloreticular agg...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307389400900315
更新日期：1994-07-01 00:00:00
abstract：:Fifty cases of postinfectious encephalomyelitis admitted to our Pediatric Department during the period 1980 to 1997 were consecutively collected and reviewed. There were 28 males and 22 females. The age of onset ranged from 9 months to 14 years. The antecedent infections included measles (6 cases), rubella (5 cases), ...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/088307380001501005
更新日期：2000-10-01 00:00:00
abstract：:Although long-term follow-up data are available for cases with acute disseminated encephalomyelitis, the findings range widely because of the lack of consistent definitions. Using the International Pediatric Multiple Sclerosis Study Group definitions strictly, we determined the long-term prognosis of children with acu...
journal_title：Journal of child neurology
pub_type： 杂志文章
doi：10.1177/0883073809343320
更新日期：2010-06-01 00:00:00
abstract：:The objective of this article is to review primary and secondary causes of carnitine deficiency, emphasizing recent advances in our knowledge of fatty acid oxidation. It is now understood that the cellular metabolism of fatty acids requires the cytosolic carnitine cycle and the mitochondrial beta-oxidation cycle. Carn...
journal_title：Journal of child neurology
pub_type： 杂志文章,评审
doi：
更新日期：1995-11-01 00:00:00
