Early upregulation of T cell IL-10 production plays an important role in oral tolerance induction.

Abstract:

:Early in oral tolerance induction, IL-10-producing CD4(+) T cells were increased, and adoptive transfer of IL-10-deficient CD4(+) T cells failed induction of oral tolerance, suggesting a key role of IL-10 production in such a process.

journal_name

Ann N Y Acad Sci

authors

Cong Y,Liu C,Weaver CT,Elson CO

doi

10.1196/annals.1309.037

subject

Has Abstract

pub_date

2004-12-01 00:00:00

pages

319-20

eissn

0077-8923

issn

1749-6632

pii

1029/1/319

journal_volume

1029

pub_type

杂志文章
  • Control of cardiac arrhythmias by calcium antagonism.

    abstract::In recent years calcium channel blockers have emerged as a new class of antiarrhythmic agents for the control of certain supraventricular and ventricular arrhythmias. Electrophysiologically, they are heterogeneous but their main action is mediated through a depressant effect on the slow calcium channel in cardiac musc...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1988.tb33397.x

    authors: Nademanee K,Singh BN

    更新日期:1988-01-01 00:00:00

  • Orbital versus dorsolateral prefrontal cortex: anatomical insights into content versus process differentiation models of the prefrontal cortex.

    abstract::Content differentiation models posit that different areas of the prefrontal cortex perform similar operations but differ in terms of the content that is operated on. For example, it has been suggested that the orbitofrontal cortex (OFC) and the dorsolateral prefrontal cortex (DLPFC) perform similar working memory or i...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1401.012

    authors: Zald DH

    更新日期:2007-12-01 00:00:00

  • Becoming musically enculturated: effects of music classes for infants on brain and behavior.

    abstract::Musical enculturation is a complex, multifaceted process that includes the development of perceptual processing specialized for the pitch and rhythmic structures of the musical system in the culture, understanding of esthetic and expressive norms, and learning the pragmatic uses of music in different social situations...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1749-6632.2012.06462.x

    authors: Trainor LJ,Marie C,Gerry D,Whiskin E,Unrau A

    更新日期:2012-04-01 00:00:00

  • Cyclooxygenase-2 expression in chronic liver diseases and hepatocellular carcinoma: an immunohistochemical study .

    abstract:UNLABELLED:Hepatocarcinogenesis is a multistep process characterized by hepatocyte inflammation, regeneration, and proliferation. These changes are believed to depend on the aberrant expression of various tumor suppressor genes, oncogenes and growth factors. Several studies have shown the involvement of cyclooxygenase-...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.03698.x

    authors: Giannitrapani L,Ingrao S,Soresi M,Florena AM,La Spada E,Sandonato L,D'Alessandro N,Cervello M,Montalto G

    更新日期:2009-02-01 00:00:00

  • Changes in antioxidant status, blood pressure, and lymphocyte DNA damage from grape juice supplementation.

    abstract::In a placebo-controlled double-blinded study, the effect of 8 weeks of grape juice was compared to the effect of isocaloric placebo juice. Volunteers with a systolic blood pressure > 130 mmHg and diastolic blood pressure > 90 mmHg were recruited. A total of 40 healthy subjects were randomized to receive isocaloric jui...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1749-6632.2009.04907.x

    authors: Park YK,Lee SH,Park E,Kim JS,Kang MH

    更新日期:2009-08-01 00:00:00

  • The sense of smell: reception of flavors.

    abstract::The sensory and hedonic evaluation of most food-related flavors is mainly dependent on olfactory perception. The sense of smell is able to recognize and discriminate myriads of airborne molecules with great accuracy and sensitivity. The primary processes of odor perception are mediated by the chemosensory olfactory ne...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1433.010

    authors: Breer H

    更新日期:2008-04-01 00:00:00

  • Protecting the privacy of patient information in clinical networks: regulatory effectiveness analysis.

    abstract::Patient privacy is one of the major issues in the development of modern clinical information system networks. Such networks will have to demonstrate an appropriate concern for privacy as a precondition of operation. Regulatory effectiveness analysis is a novel technique for measuring compliance with a technological re...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1992.tb26090.x

    authors: Brannigan VM

    更新日期:1992-12-17 00:00:00

  • Telomeres: influencing the rate of aging.

    abstract::Evidence is reviewed that suggests a central role for telomeres in one major model of biological aging, namely, proliferative senescence. Telomeric shortening with each cell division does not only act as a biological clock, but appears to trigger the ultimate loss of proliferative ability via activation of the p53-dep...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1998.tb09912.x

    authors: von Zglinicki T

    更新日期:1998-11-20 00:00:00

  • Human dendritic cells subsets as targets and vectors for therapy.

    abstract::The skin immune system includes a complex network of dendritic cells (DCs). In addition to generating cellular and humoral immunity against pathogens, skin DCs are involved in tolerogenic mechanisms that maintain immune homeostasis and in pathogenic chronic inflammation in which immune responses are unrestrained. Harn...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/nyas.12113

    authors: Klechevsky E,Banchereau J

    更新日期:2013-05-01 00:00:00

  • Treatment of suicidality in schizophrenia.

    abstract::Between 4 and 13% of people with schizophrenia commit suicide and between 25 and 50% make a suicide attempt, a reflection of the devastating toll this syndrome takes on the quality of life, that is, the subjective and objective sense of well-being. Many risk factors for suicide in schizophrenia have been identified, t...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2001.tb05797.x

    authors: Meltzer HY

    更新日期:2001-04-01 00:00:00

  • Viruses and diabetes.

    abstract::Insulin-dependent diabetes mellitus (IDDM) is a multifactorial disease. Besides a genetic predisposition environmental factors have been implicated in the pathogenesis of beta cell destruction. Among these environmental factors viruses have been the focus of many studies. Some viruses are diabetogenic in animals, and ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.2002.tb02943.x

    authors: Jaeckel E,Manns M,Von Herrath M

    更新日期:2002-04-01 00:00:00

  • Atherogenic lipoproteins resulting from genetic defects of apolipoproteins B and E.

    abstract::Accelerated atherosclerosis occurs in patients with type III hyperlipoproteinemia and familial hypercholesterolemia. These genetic disorders focus attention on specific types of lipoproteins as being responsible for the development of accelerated coronary artery heart disease. The accumulation of chylomicron remnants ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1990.tb42274.x

    authors: Weisgraber KH,Innerarity TL,Rall SC Jr,Mahley RW

    更新日期:1990-01-01 00:00:00

  • Genome hyperevolution and the success of a parasite.

    abstract::The strategy of antigenic variation is to present a constantly changing population phenotype that enhances parasite transmission, through evasion of immunity arising within, or existing between, host animals. Trypanosome antigenic variation occurs through spontaneous switching among members of a silent archive of many...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2012.06654.x

    authors: Barry JD,Hall JP,Plenderleith L

    更新日期:2012-09-01 00:00:00

  • Neuropsychological deficits in older stroke patients.

    abstract::This paper examines the frequency of CIND, the profile of early cognitive deficits in stroke patients, the differences in the profile of cognitive impairment in people with CIND and those with vascular dementia, and the MRI associations of CIND in older stroke patients. ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2002.tb04815.x

    authors: Ballard C,Stephens S,McLaren A,Wesnes K,Kenny RA,Burton E,O'Brien J,Kalaria R

    更新日期:2002-11-01 00:00:00

  • beta-Arrestin 1 couples thrombin to the rapid activation of the Akt pathway.

    abstract::In a variety of cell types including chinese hamster embryonic fibroblasts (IIC9 cells), alpha-thrombin is a potent mitogen. Thrombin irreversibly activates Par 1, a member of the seven membrane-spanning superfamily of G protein-coupled receptors (GPCRs). This, in turn, activates several heterotrimeric G proteins and ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2002.tb04622.x

    authors: Goel R,Baldassare JJ

    更新日期:2002-11-01 00:00:00

  • Genetic models to study quiescent stem cells and their niches.

    abstract::Hematopoietic stem cells (HSC) have been defined by their ability to establish long-term hematopoiesis in myelo-ablated hosts. Prospective isolation using combinations of cell-surface markers and/or dye exclusion can yield highly purified and nearly homogeneous phenotypically defined cells that repopulate irradiated h...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2009.04608.x

    authors: Schaniel C,Moore KA

    更新日期:2009-09-01 00:00:00

  • The carcinogenicity of chrysotile asbestos.

    abstract::In in vitro test systems, chrysotile is markedly toxic, causes chromosomal aberrations, and is capable of inducing morphological and preneoplastic transformation. In carefully designed animal experiments, chrysotile produces lung cancer and mesothelioma as effectively as do the amphiboles tested. Human population stud...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1111/j.1749-6632.1991.tb24496.x

    authors: Harington JS

    更新日期:1991-12-31 00:00:00

  • Neural mechanisms for the control of vergence eye movements.

    abstract::Our recent studies in non-human primates have identified and characterized cerebro-ponto-cerebellar pathways involved in the control of vergence eye movements. Specifically, within the deep cerebellar nuclei and nucleus reticularis tegmenti pontis, we have identified neurons that are related to either the near respons...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2002.tb02825.x

    authors: Gamlin PD

    更新日期:2002-04-01 00:00:00

  • Application of risk assessment to international trade in animals and animal products.

    abstract::NAFTA and GATT have specified that we must base import decisions on sound scientific information. This includes the use of risk assessment procedures to justify excluding or restricting the international movement of either live animals or products from animals. Procedures and techniques have been described for calcula...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1996.tb53535.x

    authors: Metcalf HE,Blackwell JH,Acree JA

    更新日期:1996-07-23 00:00:00

  • Cell-specific diversity in the expression and organization of cytoplasmic plaque proteins of apical junctions.

    abstract::Tight and adherens junctions play critical roles in the barrier, adhesion, and signaling functions of epithelial and endothelial cells. How the molecular organization of these junctions is tuned to the widely diverse physiological requirements of each tissue type is not well understood. Here, we address this question ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/nyas.13391

    authors: Vasileva E,Sluysmans S,Bochaton-Piallat ML,Citi S

    更新日期:2017-10-01 00:00:00

  • Handling anticancer drugs: from hazard identification to risk management?

    abstract::The potential health hazards involved with antineoplastic agents have been known for decades. Many anticancer drugs are recognized as carcinogens and genotoxins in experimental assays. Second cancers have been recorded in follow-up studies with treated patients. The first findings on occupational exposures among hospi...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1371.008

    authors: Sorsa M,Hämeilä M,Järviluoma E

    更新日期:2006-09-01 00:00:00

  • Enhanced proliferation of transfused marrow and reversal of normal growth inhibition of female marrow in male hosts 2 months after sublethal irradiation.

    abstract::We have previously shown that bone marrow will seed and proliferate in normal recipients. Transfusion of 50 million cells on each of 4 or 5 consecutive days, a total of 200-250 million cells, resulted in the recipient's marrow being 20-40% of donor origin. The present paper reported on the marked enhancement of prolif...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1985.tb20830.x

    authors: Brecher G,Mulcahy K,Tjio JH,Raveché E

    更新日期:1985-01-01 00:00:00

  • Phenotypic flexibility of skeletal muscles during long-distance migration of garden warblers: muscle changes are differentially related to body mass.

    abstract::Mass changes of skeletal muscles occur in a variety of species during the migratory period. Phenotypic flexibility of flight muscle mass is considered to represent adaptations of the flight muscle to changing power requirements associated with changes in body mass. We analyzed the relationship between muscle masses an...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1343.025

    authors: Bauchinger U,Biebach H

    更新日期:2005-06-01 00:00:00

  • Screening of aquatic and wetland plant species for phytoremediation of explosives-contaminated groundwater from the Iowa Army Ammunition Plant.

    abstract::The results of this study indicate that the presence of plants did enhance TNT and TNB removal from IAAP groundwater. Most effective at 25 degrees C were reed canary grass, coontail and pondweed. Groundwater and plant tissue analyses indicate that in presence of the plants tested TNT is degraded to reduced by-products...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.1997.tb48574.x

    authors: Best EP,Zappi ME,Fredrickson HL,Sprecher SL,Larson SL,Ochman M

    更新日期:1997-11-21 00:00:00

  • Barrett's esophagus: proton pump inhibitors and chemoprevention II.

    abstract::The following on proton pump inhibitors (PPIs) and chemoprevention in relation to Barrett's esophagus includes commentaries on 48-h pH monitoring, pH-impedence, bile acid testing, dyspepsia, long/short segment Barrett's esophagus, nonerosive reflux disease (NERD), functional heartburn, dual-release delivery PPIs, imme...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2011.06048.x

    authors: Richter JE,Penagini R,Tenca A,Pohl D,Dvorak K,Goldman A,Savarino E,Zentilin P,Savarino V,Watson JT,Wong RK,Pace F,Casini V,Peura DA,Herzig SJ,Kamiya T,Pelosini I,Scarpignato C,Armstrong D,DeVault KR,Bechi P,Tadd

    更新日期:2011-09-01 00:00:00

  • Artificial feeding in Boophilus microplus (Acari:Ixodidae) through micropipettes.

    abstract::Newly molted Boophilus microplus females obtained in a laboratory at 30 degrees C and environmental relative humidity (RH) were employed. An original device was used to hold ticks during feeding. Three groups of 15 ticks each were created: unfed, fed with heparinized blood, and fed with defibrinated blood. Ticks were ...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/j.1749-6632.2000.tb05307.x

    authors: de la Vega R,Díaz G,Finlay L

    更新日期:2000-01-01 00:00:00

  • Antagonists at metabotropic glutamate receptor subtype 5: structure activity relationships and therapeutic potential for addiction.

    abstract::As a result of intensive investigation, particularly in the pharmaceutical industry, a number of potent and selective metabotropic glutamate receptor subtype 5 (mGluR5) antagonists have been discovered. The structure activity relationship studies that led to the discovery of these mGluR5 antagonists are presented in t...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章,评审

    doi:10.1196/annals.1441.015

    authors: Carroll FI

    更新日期:2008-10-01 00:00:00

  • Role of the hedgehog/patched signaling pathway in oncogenesis: a new polymorphism in the PTCH gene in ovarian fibroma.

    abstract::We compared the expression of target genes of Hedgehog/Patched signaling in ovarian fibromas and ovarian dermoids. We noted that high levels of SHH appear almost regularly, especially in dermoids, usually accompanied by increased expression of SMO. GLI overexpression does not coincide with that of PTCH. Loss of hetero...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1196/annals.1329.017

    authors: Levanat S,Musani V,Komar A,Oreskovic S

    更新日期:2004-12-01 00:00:00

  • Reproductive aging: theoretical perspectives, mechanisms, nonhuman models, and health correlates.

    abstract::Every 365.2421999 days--more or less--the earth rotates, revolves, wobbles, and precesses along an elliptical path around the sun. Those of us who survive the journey are a year older: we have aged one solar year. Some years we seem to age faster than other years; some people seem to age faster than other people; some...

    journal_title:Annals of the New York Academy of Sciences

    pub_type:

    doi:10.1111/j.1749-6632.2010.05700.x

    authors: Haaga J,O'Connor K,Weinstein M,Wise P

    更新日期:2010-08-01 00:00:00

  • Genetic influences on musical specialization: a twin study on choice of instrument and music genre.

    abstract::Though several studies show that genetic factors influence individual differences in musical engagement, aptitude, and achievement, no study to date has investigated whether specialization among musically active individuals in terms of choice of instrument and genre is heritable. Using a large twin cohort, we explored...

    journal_title:Annals of the New York Academy of Sciences

    pub_type: 杂志文章

    doi:10.1111/nyas.13626

    authors: Mosing MA,Ullén F

    更新日期:2018-05-09 00:00:00