Emerging linezolid-resistant, vancomycin resistant Enterococcus faecium from a patient of a haematological unit in Poland.

Abstract:

:The oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including vancomycin-resistant enterococci (VRE). This is the first report on isolation of a linezolid resistant, vancomycin-resistant Enterococcus faecium (LRVREF) strain in Poland, from a Haematological Unit patient in the Clinical Hospital in Gdańsk. PCR-RFLP analysis of rDNA and allele-specific PCR of the domain V region of the 23S ribosomal RNA gene demonstrated the presence of the G2576U mutation previously reported to be associated with linezolid resistance. Both assays detected heterozygous in this position.

journal_name

Pol J Microbiol

authors

Krawczyk B,Samet A,Bronk M,Hellmann A,Kur J

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

193-6

issue

3

eissn

1733-1331

issn

2544-4646

journal_volume

53

pub_type

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