Abstract:
:The oxazolidinone antimicrobial, linezolid, has been approved for the treatment of infections caused by various gram-positive bacteria, including vancomycin-resistant enterococci (VRE). This is the first report on isolation of a linezolid resistant, vancomycin-resistant Enterococcus faecium (LRVREF) strain in Poland, from a Haematological Unit patient in the Clinical Hospital in Gdańsk. PCR-RFLP analysis of rDNA and allele-specific PCR of the domain V region of the 23S ribosomal RNA gene demonstrated the presence of the G2576U mutation previously reported to be associated with linezolid resistance. Both assays detected heterozygous in this position.
journal_name
Pol J Microbioljournal_title
Polish journal of microbiologyauthors
Krawczyk B,Samet A,Bronk M,Hellmann A,Kur Jsubject
Has Abstractpub_date
2004-01-01 00:00:00pages
193-6issue
3eissn
1733-1331issn
2544-4646journal_volume
53pub_type
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