A case of AIDS-related hepatic Kaposi's sarcoma.

abstract：BACKGROUND:This study aimed to develop a model to predict the development of severe anemia during pegylated interferon alpha-2b plus ribavirin combination therapy. METHODS:Data were collected from 1081 genotype 1b chronic hepatitis C patients who were treated at 6 hospitals in Japan. These patients were randomly assig...

journal_title：Journal of gastroenterology

authors： Hiramatsu N,Kurosaki M,Sakamoto N,Iwasaki M,Sakamoto M,Suzuki Y,Sugauchi F,Tamori A,Kakinnuma S,Matsuura K,Izumi N

更新日期：2011-09-01 00:00:00

abstract：:To investigate autonomic nervous function during upper gastrointestinal endoscopy, we analyzed R-R interval variability from electrocardiograms obtained during endoscopy. Holter electrocardiogram recordings were made before and after premedication, and during endoscopy. Time- and frequency-domain analyses of heart rat...

journal_title：Journal of gastroenterology

authors： Hayashi T,Nomura M,Honda H,Tezuka K,Torisu R,Takeuchi Y,Nakaya Y,Ito S

更新日期：2000-01-01 00:00:00

abstract：:We simultaneously recorded gastric emptying of radio-opaque markers (ROMs) and monitored serial changes in plasma acetaminophen (AAP) levels to demonstrate the relationship between the ROM and the AAP methods, and we investigated the effect of a single intravenous dose of erythromycin (EM) on gastric emptying in healt...

journal_title：Journal of gastroenterology

authors： Park HJ,Jung JK,Song KS,Lee SI,Itoh Z,Park IS

更新日期：1997-12-01 00:00:00

abstract：:Although the causes of inflammatory bowel disease (IBD) remain incompletely understood, increasing evidence implicates intestinal microflora in the pathogenesis of these disorders. Alteration of intestinal flora therefore may offer a plausible therapeutic approach. Although recent data support a potential therapeutic ...

journal_title：Journal of gastroenterology

authors： Mitsuyama K,Toyonaga A,Sata M

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Although colorectal cancer (CRC) is one of the most common causes of cancer mortality, early-stage detection improves survival rates dramatically. Because cancer impacts important metabolic pathways, the alteration of metabolite levels as a potential biomarker of early-stage cancer has been the focus of many...

journal_title：Journal of gastroenterology

authors： Uchiyama K,Yagi N,Mizushima K,Higashimura Y,Hirai Y,Okayama T,Yoshida N,Katada K,Kamada K,Handa O,Ishikawa T,Takagi T,Konishi H,Kuriu Y,Nakanishi M,Otsuji E,Itoh Y,Naito Y

更新日期：2017-06-01 00:00:00

abstract：:An association between macrovascular thrombosis and idiopathic inflammatory bowel disease has been described, although very few well-documented cases have been published. We report on a 39-year-old woman who presented with right hemifacial and upper limb edema that was shown to be due to an extensive right brachioceph...

journal_title：Journal of gastroenterology

authors： Ribeiro JM,Rebocho L,Lucas MB,Campos P,Victorino RM

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Little is known about the difference in enhancement patterns of hepatocellular carcinoma (HCC) during multistep hepatocarcinogenesis between the post-vascular phase of Sonazoid-enhanced ultrasonography (SEUS) and hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine (Gd-EOB-DTPA)-enhanced MRI, as...

journal_title：Journal of gastroenterology

authors： Ohama H,Imai Y,Nakashima O,Kogita S,Takamura M,Hori M,Seki Y,Sawai Y,Igura T,Fukuda K,Makino Y,Morimoto O,Ohsawa M,Sakamoto M,Murakami T

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:There have been few epidemiological studies on gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in Japan. METHODS:We examined the epidemiology of GEP-NETs [pancreatic endocrine tumors (PETs) and gastrointestinal neuroendocrine tumors (GI-NETs)] in Japan in 2005 using a nationwide stratified random sa...

journal_title：Journal of gastroenterology

authors： Ito T,Sasano H,Tanaka M,Osamura RY,Sasaki I,Kimura W,Takano K,Obara T,Ishibashi M,Nakao K,Doi R,Shimatsu A,Nishida T,Komoto I,Hirata Y,Nakamura K,Igarashi H,Jensen RT,Wiedenmann B,Imamura M

更新日期：2010-02-01 00:00:00

abstract：:Prevention of human diseases has become a major focus of biomedical investigators around the world. Our current screening and treatment regimens for colorectal cancer are not effective, as indicated by the fact that this disease is the second leading cause of death from cancer in the United States. Recently published ...

journal_title：Journal of gastroenterology

authors： DuBois RN,Smalley WE

更新日期：1996-12-01 00:00:00

abstract：:Cyclin D1 overexpression is remarkably frequent in several human carcinomas and is believed to be a critical event in oncogenesis. We examined cyclin D1 expression, p53 expression, and the Ki-67 labeling index by immunostaining in human gallbladder mucosa in conditions varying from normal to malignant tissue. We also ...

journal_title：Journal of gastroenterology

authors： Itoi T,Shinohara Y,Takeda K,Nakamura K,Takei K,Sanada J,Horibe T,Saito T,Kasuya K,Ebihara Y

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The ideal medication for the treatment of acid-related diseases, for example, hemorrhagic ulcers and stress-related gastric bleeding, should have a rapid onset of action to promote hemostasis and alleviate symptoms. The aim of our study was to investigate the inhibitory effects on gastric acid secretion afte...

journal_title：Journal of gastroenterology

authors： Abe Y,Inamori M,Togawa J,Kikuchi T,Muramatsu K,Chiguchi G,Kawamura H,Kobayashi N,Kirikoshi H,Sakaguchi T,Takamura T,Nakajima A,Ueno N,Sekihara H

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Oropharyngeal dysphagia (OD) is a major gastrointestinal motility disorder that causes severe nutritional and respiratory complications in elderly and neurological patients. In an earlier study, we found that stimulation of pharyngeal sensory neurons by capsaicinoids acting on transient receptor potential va...

journal_title：Journal of gastroenterology

authors： Rofes L,Arreola V,Martin A,Clavé P

更新日期：2014-12-01 00:00:00

abstract：:Cholecystokinin (CCK) receptor antagonists have been reported on have an inhibitory effect on acute experimental pancreatitis, but their long-term administration is also reported to block pancreatic regeneration. We examined whether the short-term administration of KSG-504 (KSG), a synthetic CCK-A receptor antagonist,...

journal_title：Journal of gastroenterology

authors： Okumura Y,Inoue H,Fujiyama Y,Bamba T

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Gastric marker mucins (MUC5AC and MUC6) and intestinal marker molecules (MUC2 and CD10) have been used to determine the cell lineage of epithelial cell of gastric carcinoma (GC). METHODS:To clarify the characteristics of Epstein-Barr virus (EBV)-associated GC, 18 cases were immunohistochemically evaluated a...

journal_title：Journal of gastroenterology

authors： Barua RR,Uozaki H,Chong JM,Ushiku T,Hino R,Chang MS,Nagai H,Fukayama M

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Insulin-like growth factor (IGF)-I receptor (IGF-IR) signaling plays important parts in both the tumorigenicity and progression of digestive/gastrointestinal malignancies. In this study, we sought to test the effectiveness of a practical approach to blocking IGF-IR signaling using RNA interference d...

journal_title：Journal of gastroenterology

authors： Wang Y,Adachi Y,Imsumran A,Yamamoto H,Piao W,Li H,Ii M,Arimura Y,Park MY,Kim D,Lee CT,Carbone DP,Imai K,Shinomura Y

更新日期：2010-02-01 00:00:00

abstract：:Eosinophilic esophagitis (EE) is a rarely diagnosed condition involving eosinophilic infiltration of the esophageal mucosa. Here we present a case of EE in a 69-year-old Japanese man, who presented with abdominal pain, appetite loss, and a history of bronchial asthma. Laboratory findings included peripheral eosinophil...

journal_title：Journal of gastroenterology

authors： Furuta K,Adachi K,Kowari K,Mishima Y,Imaoka H,Kadota C,Koshino K,Miyake T,Kadowaki Y,Furuta K,Kazumori H,Sato S,Ishihara S,Amano Y,Honda M,Kinoshita Y

更新日期：2006-07-01 00:00:00

abstract：:Magnetic resonance imaging (MRI) findings in three patients with primary anorectal malignant melanoma are described. Two patients had melanotic and one had amelanotic anorectal melanoma. The findings of MRI with a pelvic coil and an endorectal coil were consistent with pathologic findings. MRI with a pelvic coil demon...

journal_title：Journal of gastroenterology

authors： Matsuoka H,Nakamura A,Iwamoto K,Sugiyama M,Hachiya J,Atomi Y,Masaki T

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Recently, the novel gene DOG1 has been found to be overexpressed in most gastrointestinal stromal tumors (GISTs) specifically within the field of soft tissue tumors. DOG1 might play a role in development of GISTs and have potential as a diagnostic marker and therapeutic target, but the biological function an...

journal_title：Journal of gastroenterology

authors： Miwa S,Nakajima T,Murai Y,Takano Y,Sugiyama T

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Subunit A of coagulation factor XIII (FXIII-A) is important for clot stability and acts in the subsequent wound healing process. Loss of plasma FXIII-A has been reported after surgery, sepsis, and inflammatory conditions. In the intestinal mucosa, FXIII-A is expressed by macrophages and cellular FXIII-A has ...

journal_title：Journal of gastroenterology

authors： Soendergaard C,Kvist PH,Seidelin JB,Pelzer H,Nielsen OH

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:A combination of hepatitis B immunoglobulin and nucleos(t)ide analogues is the current standard of care for controlling hepatitis B recurrence after orthotopic liver transplantation (OLT). However, frequent immunoglobulin treatment is expensive and inconvenient. This study investigated the efficacy of hepati...

journal_title：Journal of gastroenterology

authors： Takaki A,Yagi T,Yasunaka T,Sadamori H,Shinoura S,Umeda Y,Yoshida R,Sato D,Nobuoka D,Utsumi M,Yasuda Y,Nakayama E,Miyake Y,Ikeda F,Shiraha H,Nouso K,Fujiwara T,Yamamoto K

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

journal_title：Journal of gastroenterology

authors： Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

更新日期：2015-04-01 00:00:00

abstract：:A patient with familial adenomatous polyposis (FAP) presented with a relapsing attack of acute pancreatitis. Evaluation using computed tomography, ultrasonography, and duodenoscopy revealed an ampullary adenoma, which was classified as Spigelman's stage III according to Spigelman's criteria. The patient underwent a py...

journal_title：Journal of gastroenterology

authors： Murakami Y,Uemura K,Hayashidani Y,Sudo T,Sueda T

更新日期：2006-08-01 00:00:00

abstract：:In this study, we quantitatively measured glycogen levels in tissue samples obtained from tumors, regions adjacent to tumor, and regions of normal colorectum to determine whether the levels were related to cell cycle and cancer growth. Glycogen levels were analyzed in relation to histopathological factors, (tumor size...

journal_title：Journal of gastroenterology

authors： Takahashi S,Satomi A,Yano K,Kawase H,Tanimizu T,Tuji Y,Murakami S,Hirayama R

更新日期：1999-08-01 00:00:00

abstract：:A rare case of simple ulcer of the colon in a 7-year-old girl is reported. Simple ulcer is clinically and pathologically recognized as a serious disease linked to intestinal Behcet's disease. Recently, some immunomodulators, such as thalidomide and antitumor necrosis factor monoclonal antibody, have been used to treat...

journal_title：Journal of gastroenterology

authors： Kasahara E,Yamagishi N,Tanaka M,Yashiro K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Infection with Helicobacter pylori is the main risk factor for development of gastric cancer. CD44 overexpression, especially that of variant 9 (CD44v9), has also been implicated in the local inflammatory response and metaplasia-carcinoma sequence in human stomach. We recently identified miR-328 as one of th...

journal_title：Journal of gastroenterology

authors： Ishimoto T,Izumi D,Watanabe M,Yoshida N,Hidaka K,Miyake K,Sugihara H,Sawayama H,Imamura Y,Iwatsuki M,Iwagami S,Baba Y,Horlad H,Komohara Y,Takeya M,Baba H

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:To provide updated clinico-epidemiological information on chronic pancreatitis (CP) in Japan. METHODS:We conducted a two-stage nationwide epidemiological survey; the number of CP patients was estimated in the first-stage survey, and their clinical features were examined in the second-stage survey. We survey...

journal_title：Journal of gastroenterology

authors： Masamune A,Kikuta K,Kume K,Hamada S,Tsuji I,Takeyama Y,Shimosegawa T,Okazaki K,Japan Pancreas Society.

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:This hospital-based analysis was conducted to identify prognostic factors of hepatocellular carcinoma (HCC) in a hepatitis B virus endemic area. METHODS:A total of 6381 HCC cases, diagnosed from 1986 to 2002, were enrolled, and 2890 (42.3%) of them were not treated. Survival rates were analyzed by correlati...

journal_title：Journal of gastroenterology

authors： Changchien CS,Chen CL,Yen YH,Wang JH,Hu TH,Lee CM,Wang CC,Cheng YF,Huang YJ,Lin CY,Lu SN

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:There have only been a few prospective studies investigating risk factors associated with the development of hepatocellular carcinoma (HCC) among chronic hepatitis B patients all over the world, and no study has been conducted in Japanese population. METHODS:A population-based cohort consisting of 19393 sub...

journal_title：Journal of gastroenterology

authors： Kusakabe A,Tanaka Y,Inoue M,Kurbanov F,Tatematsu K,Nojiri S,Joh T,Tsugane S,Mizokami M

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Single nucleotide polymorphisms (SNPs) of the adiponectin gene have been reported to be associated with insulin resistance and the prevalence of type-2 diabetes. We investigated the SNPs of adiponectin in non-alcoholic fatty liver disease (NAFLD) patients. METHODS:One hundred nineteen patients histologically d...

journal_title：Journal of gastroenterology

authors： Tokushige K,Hashimoto E,Noto H,Yatsuji S,Taniai M,Torii N,Shiratori K

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:King's College Hospital (KCH) criteria and the model for end-stage liver disease (MELD) score are useful and widely-employed prognostic markers for acute liver failure (ALF). We previously reported that liver atrophy is an important prognostic factor for ALF. The aim of the present study was to assess t...

journal_title：Journal of gastroenterology

authors： Yamagishi Y,Saito H,Ebinuma H,Kikuchi M,Ojiro K,Kanamori H,Tada S,Horie Y,Kato S,Hibi T

更新日期：2009-01-01 00:00:00