Abstract:
BACKGROUND:Migraine and headache in general have been associated with subsequent risk of stroke, primarily in retrospective case-control studies. Prospective data evaluating the association between specific headache forms and stroke are sparse. METHODS:A prospective cohort study was conducted among 39,754 US health professionals age 45 and older participating in the Women's Health Study with an average follow-up of 9 years. Incident stroke was self-reported and confirmed by medical record review. RESULTS:A total of 385 strokes (309 ischemic, 72 hemorrhagic, and 4 undefined) occurred. Compared with nonmigraineurs, participants who reported migraine overall or migraine without aura had no increased risk of any stroke type. Participants who reported migraine with aura had increased adjusted hazards ratios (HRs) of 1.53 (95% CI 1.02 to 2.31) for total stroke and 1.71 (95% CI 1.11 to 2.66) for ischemic stroke but no increased risk for hemorrhagic stroke. Participants with migraine with aura who were <55 years old had a greater increase in risk of total (HR 1.75; 95% CI 1.02 to 3.00) and ischemic (HR 2.25; 95% CI 1.30 to 3.91) stroke. Compared with participants without headache, headache in general and nonmigraine headache were not associated with total, ischemic, or hemorrhagic stroke. CONCLUSIONS:In these prospective data, migraine was not associated with total, ischemic, or hemorrhagic stroke. In subgroup analyses, we found increased risks of total and ischemic stroke for migraineurs with aura. The absolute risk increase was, however, low, with 3.8 additional cases per year per 10,000 women.
journal_name
Neurologyjournal_title
Neurologyauthors
Kurth T,Slomke MA,Kase CS,Cook NR,Lee IM,Gaziano JM,Diener HC,Buring JEdoi
10.1212/01.WNL.0000154528.21485.3Asubject
Has Abstractpub_date
2005-03-22 00:00:00pages
1020-6issue
6eissn
0028-3878issn
1526-632Xpii
64/6/1020journal_volume
64pub_type
杂志文章相关文献
NEUROLOGY文献大全abstract:OBJECTIVE:To determine the diagnostic accuracy and prognostic value of ¹⁸FDG-PET in a recent series of patients operated for intractable partial epilepsy associated with histologically proven Taylor-type focal cortical dysplasia (TTFCD) and negative MRI. METHODS:Of 23 consecutive patients (12 male, 7-38 years old) wit...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e31820203a9
更新日期:2010-12-14 00:00:00
abstract::We analyzed ictal features of psychogenic seizures using video-EEG recordings in 47 patients and reviewed the medical records to determine if patients received antiepileptic drug therapy and whether they were treated pharmacologically for status epilepticus. Unresponsive behavior in the absence of motor manifestations...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.1.95
更新日期:1992-01-01 00:00:00
abstract:OBJECTIVE:To combine MRI-based cortical morphometry and diffusion white matter tractography to describe the anatomical correlates of repetition deficits in patients with primary progressive aphasia (PPA). METHODS:The traditional anatomical model of language identifies a network for word repetition that includes Wernic...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000008746
更新日期:2020-02-11 00:00:00
abstract::Lyme borreliosis (LB) causes a range of neurologic manifestations, the most common of which is facial nerve paralysis. To evaluate nervous system LB, we organized a neurologic collaborative study group in Suffolk County, NY, a region of high LB incidence. Between July and September 1989, LB serologies were performed o...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.42.7.1268
更新日期:1992-07-01 00:00:00
abstract:OBJECTIVES:To investigate whether the human sciatic nerve might have a consistent somatotopic organization according to proximal fascicle input by spinal nerves. METHODS:Twelve patients (55.3 ± 15.5 years) with confirmed lesions of either the L5 or S1 spinal nerve root underwent magnetic resonance neurography of sciat...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000001526
更新日期:2015-04-28 00:00:00
abstract:OBJECTIVE:To determine the accuracy of the clinical history performed by epileptologists in the identification of seizures in patients with suspected temporal lobe epilepsy. METHODS:The clinical and EEG telemetry (EEGT) monitoring data of 88 patients with suspected refractory temporal lobe seizures referred for evalua...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/01.wnl.0000090566.40544.04
更新日期:2003-12-23 00:00:00
abstract:OBJECTIVE:To determine the effect of injections of botulinum toxin on simple motor tics. BACKGROUND:Case series with unblinded assessments have reported improvement in tic frequency and associated urge with botulinum toxin. METHODS:Patients with suitable simple motor tics were randomized to receive botulinum toxin an...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.56.5.605
更新日期:2001-03-13 00:00:00
abstract:OBJECTIVE:To describe the clinical features, neuropathology, and genetic studies in a family with autosomal dominant frontotemporal dementia (FTD). BACKGROUND:Clinical Pick's disease, or FTD with parkinsonism, has been described in several families linked to chromosome 17 (FTDP-17). Most of these have shown tau protei...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.54.4.818
更新日期:2000-02-22 00:00:00
abstract:BACKGROUND:Among patients with a patent foramen ovale (PFO) and a prior cryptogenic ischemic stroke or TIA, the absolute and relative risk of recurrent events is unclear. METHODS:We conducted a systematic review and meta-analysis of clinical studies in any language published up to February 2008. We included studies re...
journal_title:Neurology
pub_type: 杂志文章,meta分析,评审
doi:10.1212/WNL.0b013e3181aa2a19
更新日期:2009-07-14 00:00:00
abstract:OBJECTIVE:We tested the hypothesis that admission serum magnesium levels are associated with hematoma volume, hematoma growth, and functional outcomes in patients with intracerebral hemorrhage (ICH). METHODS:Patients presenting with spontaneous ICH were enrolled in an observational cohort study that prospectively coll...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000004249
更新日期:2017-08-22 00:00:00
abstract::All but 6% of the subjects with relapsing remitting MS who were randomly assigned to receive glatiramer acetate or placebo for the 9-month controlled phase of the European/Canadian MRI trial entered an open-label extension with quarterly clinical and MRI evaluations for another 9 months. There was a 54% reduction in t...
journal_title:Neurology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1212/wnl.59.8.1284
更新日期:2002-10-22 00:00:00
abstract:OBJECTIVE:To report 5-year outcomes from the subthalamic nucleus (STN) deep brain stimulation (DBS) in early-stage Parkinson disease (PD) pilot clinical trial. METHODS:The pilot was a prospective, single-blind clinical trial that randomized patients with early-stage PD (Hoehn & Yahr II off medications) to receive bila...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/WNL.0000000000009946
更新日期:2020-07-28 00:00:00
abstract:OBJECTIVE:We performed a longitudinal cohort study of infants with tuberous sclerosis complex (TSC), with the overarching goal of defining early clinical, behavioral, and biological markers of autism spectrum disorder (ASD) in this high-risk population. METHODS:Infants with TSC and typically developing controls were r...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000000568
更新日期:2014-07-08 00:00:00
abstract::We developed a scheme using routinely available data to estimate the risk of human immunodeficiency virus (HIV) dementia in HIV-infected persons over time. We performed a longitudinal review of medical records from more than 100 medical facilities in 11 U.S. cities. A total of 19,462 HIV-infected persons without histo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.50.2.392
更新日期:1998-02-01 00:00:00
abstract::We tested the hypothesis that an anticardiolipin antibody (aCL) titer of > or = 10 IgG phospholipid (GPL) at the time of an index ischemic stroke is associated with an increased risk of subsequent thrombo-occlusive events or death. First-time ischemic stroke patients from the Antiphospholipid Antibodies and Stroke Stu...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.48.1.91
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Inherited and de novo mutations in sodium channel genes underlie a variety of channelopathies. Mutations in SCN2A, encoding the brain sodium channel Na(V)1.2, have previously been reported to be associated with benign familial neonatal infantile seizures, febrile seizures plus, and intractable epilepsy of in...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181f8812e
更新日期:2010-10-19 00:00:00
abstract:OBJECTIVE:To report the incidence of prion disease in the United States. METHODS:Prion disease decedents were retrospectively identified from the US national multiple cause-of-death data for 2003-2015 and matched with decedents in the National Prion Disease Pathology Surveillance Center (NPDPSC) database through compa...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000008680
更新日期:2020-01-14 00:00:00
abstract::To assess reversibility of focal cerebral ischemia, we performed a neurologic and pathologic study of 27 monkeys subjected to temporary middle cerebral artery occlusion. An implanted snare ligature occluded the artery in awake monkeys for 30 minutes, 4 hours, 8 hours, 16 hours, 24 hours, or permanently. Serial neurolo...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.31.10.1295
更新日期:1981-10-01 00:00:00
abstract::We previously described demyelination in the brain and subacute combined degeneration of the spinal cord in a patient with 5,10-methylenetetrahydrofolate reductase deficiency. To assess the role of methionine, S-adenosylmethionine, folate, and neurotransmitter amine metabolism in the demyelination process, we measured...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.38.3.459
更新日期:1988-03-01 00:00:00
abstract::Hypnic headache has been described in several case reports since 1981 and is regarded as an idiopathic headache disorder. In this review of 71 cases in the literature, the clinical features, neurophysiologic including polysomnographic findings, and treatment procedures are analyzed and the pathophysiology of this cond...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:10.1212/01.wnl.0000046582.21771.9c
更新日期:2003-03-25 00:00:00
abstract:OBJECTIVE:To determine factors (including the role of specific disease modulatory treatments [DMTs]) associated with (1) baseline, (2) on-treatment, and (3) change (from treatment start to on-treatment assessment) in plasma neurofilament light chain (pNfL) concentrations in relapsing-remitting multiple sclerosis (RRMS)...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0000000000009097
更新日期:2020-03-17 00:00:00
abstract:OBJECTIVE:To assess longitudinal follow-up of the incidence of multiple sclerosis (MS) through five decades and estimate the prevalence rate in Hordaland County, Norway, on January 1, 2003. METHODS:All patients with MS diagnosed from 1953 to 2003 were identified in the patient records of the Department of Neurology, H...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.wnl.0000195549.95448.b9
更新日期:2006-01-24 00:00:00
abstract::Anti-Leu 7 antibody reacts with determinants on a subset of natural killer (NK) cells and myelin-associated glycoprotein (MAG). In a patient patient with peripheral neuropathy and IgM autoantibodies against MAG, we found the distribution and functions of NK cells to be normal. ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.36.4.566
更新日期:1986-04-01 00:00:00
abstract::Many patients with epilepsy can be successfully treated with a single antiepileptic drug (monotherapy). However, in a substantial number of patients, monotherapy does not provide satisfactory seizure control, and the use of two or more drugs, or polypharmacy, is required. Selection of rational combination therapy requ...
journal_title:Neurology
pub_type: 杂志文章,评审
doi:
更新日期:1995-03-01 00:00:00
abstract::To define the natural history of asymptomatic meningioma found incidentally on a neuroimaging study, we performed a retrospective analysis of 35 such patients. There were 32 women and three men, with a mean age of 67 years and a mean follow-up of 74 months. Four tumors had progressed on subsequent imaging, and one pat...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.51.6.1718
更新日期:1998-12-01 00:00:00
abstract::Primary lateral sclerosis (PLS) is a diagnosis of exclusion in patients with progressive spinobulbar spasticity and could be part of the clinical spectrum of ALS. Unlike ALS, which is familial in 5 to 10% of the cases, PLS has been described as a sporadic disorder in adults. The authors report two patients with PLS fr...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/01.WNL.0000162033.47893.F7
更新日期:2005-05-24 00:00:00
abstract::Inclusion-body myositis (IBM) is an inflammatory muscle disease that has proven resistant to treatment. Tumor necrosis factor molecules have been detected in muscle biopsies from patients with IBM. Etanercept is a TNFalpha receptor fusion protein that binds and inactivates tumor necrosis factor. Nine patients were tre...
journal_title:Neurology
pub_type: 临床试验,杂志文章
doi:10.1212/01.wnl.0000192258.32408.54
更新日期:2006-01-24 00:00:00
abstract:OBJECTIVES:To describe the clinical, CSF, and radiologic findings and long-term follow-up in a cohort of patients with acute disseminated encephalomyelitis (ADEM), and to determine possible prognostic factors for progression to MS. METHODS:Forty adults (28 women, mean age 33.5 years) diagnosed with ADEM were analyzed....
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/wnl.56.10.1313
更新日期:2001-05-22 00:00:00
abstract:BACKGROUND:According to the International Classification of Headache Disorders (ICHD)-2, primary daily headaches unremitting from onset are classified as new daily-persistent headache (NDPH) only if migraine features are absent. When migraine features are present, classification is problematic. METHODS:We developed a ...
journal_title:Neurology
pub_type: 杂志文章
doi:10.1212/WNL.0b013e3181dad5de
更新日期:2010-04-27 00:00:00
abstract::Two successive, 6-month, randomized, double-blind, controlled trials of prednisone showed that 0.75 mg/kg/d was the optimal dose to improve strength in boys with Duchenne muscular dystrophy (DMD). We attempted to maintain 93 boys on that dose for an additional 2 years. During the 3 years of observation, the decline in...
journal_title:Neurology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1212/wnl.41.12.1874
更新日期:1991-12-01 00:00:00