Abstract：
OBJECTIVE:Although fatigue is a common debilitating complaint in multiple sclerosis (MS), its relationship to the cardiopulmonary exercise response has yet to be defined. DESIGN:A patient with MS manifested primarily by profound fatigue undergoes complete pulmonary function testing and a maximal incremental cycle ergometry study with gas exchange measurements and determination of ejection fractions. SETTING:Outpatient, community hospital pulmonary function laboratory. RESULTS:The patient is found to have respiratory muscle weakness and a severely depressed exercise performance. The latter was associated with an early anaerobic threshold but a normal central cardiovascular response (radionuclide ventriculography), implying problems in peripheral O2 distribution/utilization. The respiratory muscle involvement, although substantial, was nonlimiting to the exercise performance. CONCLUSIONS:Despite its central neuropathophysiology, MS as it relates to fatigue may be associated with an abnormal peripheral exercise response, namely, problems in peripheral O2 utilization. Such a concept could prove invaluable as it would provide a physiological basis for defining the severity and therapy of "MS fatigue."
journal_name
Arch Phys Med Rehabiljournal_title
Archives of physical medicine and rehabilitationauthors
Vaz Fragoso CA,Wirz D,Mashman Jdoi
10.1016/s0003-9993(95)80515-xsubject
Has Abstractpub_date
1995-06-01 00:00:00pages
583-6issue
6eissn
0003-9993issn
1532-821Xpii
S0003-9993(95)80515-Xjournal_volume
76pub_type
杂志文章abstract：OBJECTIVE:To evaluate of the efficacy and safety of 8 hours of continuous, low-level heatwrap therapy administered during sleep. DESIGN:Prospective, randomized, parallel, single-blind (investigator), placebo-controlled, multicenter clinical trial. SETTING:Two community-based research facilities. PARTICIPANTS:Seventy...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1053/apmr.2003.50103
更新日期：2003-03-01 00:00:00
abstract：:Patients with viable phrenic nerves and adequate diaphragm and lung function can be freed from mechanical ventilation by the use of phrenic nerve pacers. Four quadriplegic patients with phrenic nerve pacers were admitted to a rehabilitation facility between April 1981 and September 1986. These patients made significan...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
abstract：:The muscle fibers of the biceps brachii muscle were stimulated distally with low voltage by means of two monopolar needles in 14 boys with Duchenne muscular dystrophy (DD). The electric activity was recorded proximally by means of a SFEMG electrode. The mean conduction velocity of 508 muscle fibers in situ (MFCV) calc...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1990-07-01 00:00:00
abstract：OBJECTIVES:To determine the effects of 1.0 mg/kg nitro-L-arginine methyl ester (L-NAME) on orthostatic mean arterial pressure (MAP), serum aldosterone, and plasma renin concentrations in persons with chronic tetraplegia compared with nonspinal cord-injured controls. DESIGN:Prospective placebo-controlled intervention s...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2009.02.004
更新日期：2009-08-01 00:00:00
abstract：:Pulmonary embolus can have insidious onset and unusual etiology. This case report of a 35-year-old woman with hyperthyroidism, atrial fibrillation, and an above-knee amputation demonstrates the subtle presentation of pulmonary emboli. On the rehabilitation ward of a tertiary care hospital, the patient developed undula...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：OBJECTIVE:To investigate how exercise training and detraining affect oxidized low-density lipoprotein (Ox-LDL)-potentiated platelet function in men. DESIGN:Cohort study. SETTING:Department of physical medicine and rehabilitation. PARTICIPANTS:Ten sedentary men (mean age +/- standard error of the mean, 21.6+/-0.2 y) ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.08.112
更新日期：2004-09-01 00:00:00
abstract：:Sciatic nerve entrapment in an osseous tunnel has only been reported twice previously. We describe a 19-year-old man evaluated for left lower limb pain and weakness that began one and one half years after sustaining stab wounds to the left buttock and midline back near the T11 vertebrae. The patient had sciatica and d...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(93)90124-s
更新日期：1993-05-01 00:00:00
abstract：:Assessment of strength using motor scores derived from the standards of the American Spinal Injury Association (ASIA) was compared with assessment using motor scores based on biomechanical aspects of walking in the prediction of ambulatory performance. Measurements of strength, gait performance, and the energy expendi...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:To examine the effects of an individualized physical therapy (PT) program for a subject with pectus excavatum and bilateral shoulder pain. DESIGN:Single-case study of a man diagnosed with moderate-to-severe pectus excavatum and constant bilateral shoulder pain. Exercise tolerance was measured through the Bru...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2008.04.014
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVE:To report on the effectiveness and side effects of 2% phenol block in patients with cervical dystonia (CD). DESIGN:Case series. SETTING:A rehabilitation department at a university medical center in Japan. PARTICIPANTS:Sixteen patients (11 men, 5 women; mean age +/- standard deviation, 43.4+/-11.2y) with CD...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2003.10.012
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:To determine the location of cortical activation during a visual illusion walking paradigm, a recently proposed treatment for spinal cord injury (SCI)-related neuropathic pain, in persons with SCI compared with able-bodied controls. DESIGN:Pilot experimental functional magnetic resonance imaging (fMRI) trial...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2014.10.020
更新日期：2015-04-01 00:00:00
abstract：:Pathology influencing the serratus anterior muscle contributes to classical medial winging of the scapula. Serratus anterior weakness or injury interferes with regular shoulder movement as this muscle stabilizes the medial border of the scapula against the thorax and rotates the scapula upward and laterally with arm e...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(86)90018-3
更新日期：1986-10-01 00:00:00
abstract：:Systemic malignancy can be manifested by musculoskeletal complaints. We review the history, physical examination, and diagnostic imaging studies of a patient whose chief complaints were neck and shoulder pain. This patient also had significant weight loss and a history of tobacco abuse. Aggressive physical therapy and...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(94)90118-x
更新日期：1994-08-01 00:00:00
abstract：:Hyposexuality is a common problem in stroke patients. Some stroke patients, however, may present with hypersexuality. We report three stroke patients who demonstrated hypersexuality and deviant sexual behavior after stroke. Abnormal sexual behavior was noted by members of the stroke rehabilitation team while the patie...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
abstract：:Two cases of ulnar nerve lesions at the wrist are reported. The lesions had an acute onset and exclusively impaired the ulnar motor deep branch. The coexistence of carpal tunnel syndrome in each case allowed an early diagnosis but was somewhat misleading. In both cases, the use of classic motor and sensory conduction ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/s0003-9993(99)90042-4
更新日期：1999-10-01 00:00:00
abstract：:A quadriplegic patient with a C6 lesion had a stroke with aphasia and right hemiplegia 20 years after his cervical cord injury. The combination of hemiplegia and quadriplegia created unusual rehabilitation problems, the most disabling of which was a painful flexion contracture of the right elbow that prevented any use...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1984-12-01 00:00:00
abstract：:This case report describes a 2-year treatment course of a 6-year-old with spastic paraparesis due to human immunodeficiency virus (HIV) encephalopathy. She continued to develop worsening musculoskeletal problems and a decline in mobility despite aggressive antispasticity interventions. In addition to meeting the usual...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2006.03.015
更新日期：2006-07-01 00:00:00
abstract：:This study explores relationships between behavior of spinal cord injured persons during hospitalization and their medical and behavioral status after discharge. It illustrates a logic for identifying, selecting and testing indicators of patient performance that predict important aspects of outcome. Key behavioral mea...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1981-12-01 00:00:00
abstract：:Every medical student at Mayo Medical School participates in a three-week training program in the department of physical medicine and rehabilitation. Since 1974-1975, approximately 40 students have had this experience each academic year. In addition to lectures, the learning experience includes clinical cases involvin...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：OBJECTIVE:To investigate the effect of a 2-year vigorous, combined high-impact, strength, and endurance training program on bone mineral density (BMD) determined by dual-energy x-ray absorptiometry (DXA), quantitative computed tomography (QCT), and ultrasound in early postmenopausal women with osteopenia. DESIGN:Nonra...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章
doi：10.1016/s0003-9993(02)04908-0
更新日期：2003-05-01 00:00:00
abstract：:The purpose of this case study was to determine whether an individual who had residual deficits following an acute incidence of Guillain-Barre Syndrome (GBS) would experience improved physiological adaptations following aerobic endurance training. A 57-year-old man who needed the aid of a crutch for walking three year...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(93)90039-d
更新日期：1993-07-01 00:00:00
abstract：OBJECTIVE:To determine if women's dress shoes with heels of just 1.5 in (3.8 cm) in height increases knee joint torques, which are thought to be relevant to the development and/or progression of knee osteoarthritis (OA) in both the medial and patellofemoral compartments. DESIGN:Randomized controlled trial. SETTING:A ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.apmr.2004.09.018
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To identify instruments that measure community participation in people with disabilities and to evaluate which domains, to what extent, and how precisely they address this construct. The review aims to provide information to guide the selection of community participation instruments and to identify limitation...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.apmr.2012.10.031
更新日期：2013-04-01 00:00:00
abstract：:Piriformis syndrome (PS) is defined by a loose cluster of symptoms arising from entrapment of one or both divisions of the sciatic nerve as they pass the sciatic notch. This paper presents a method of using the H-reflex as an aid in the diagnosis of PS. Forcible pressure from the piriformis muscle on the sciatic nerve...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/0003-9993(92)90010-t
更新日期：1992-04-01 00:00:00
abstract：OBJECTIVE:To determine the predictive value of discharge destination as a surrogate for defining unfavorable outcome at 3- and 12-months poststroke. DESIGN:Analysis of the prospectively collected data from a randomized, placebo-controlled trial in patients with ischemic stroke presenting within 3 hours of symptom onse...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2012.02.032
更新日期：2012-08-01 00:00:00
abstract：:Dysphagia is a problem commonly treated and frequently diagnosed on the rehabilitation unit. It can be caused by trauma, injury, or diseases of the nervous system and can result in potentially serious and life threatening complications. The disruption of normal swallowing has also been reported to occur in psychiatric...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
abstract：:Quantification of cervical extension (CERV EXT) strength is complicated by the inability to stabilize the torso and isolate the CERV EXT muscles. A newly developed machine designed to stabilize the torso and isolate the CERV EXT muscles was used to evaluate the effect of frequency and volume of resistance training on ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0003-9993(93)90065-i
更新日期：1993-10-01 00:00:00
abstract：OBJECTIVE:To determine how total physical rehabilitation needs have been distributed per relevant condition groups (musculoskeletal and pain, neurologic cardiothoracic, neoplasms, pediatric, human immunodeficiency virus [HIV] related), globally and across countries of varying income level. DESIGN:Subgroup, secondary a...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：10.1016/j.apmr.2019.12.020
更新日期：2020-06-01 00:00:00
abstract：:Reproductive rehabilitation of men after spinal cord injury has been made possible by the application of assisted ejaculatory techniques such as electroejaculation. Although this technique may predictably overcome the barrier of semen recovery, the problem of seminal dysfunction still remains. This report describes on...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:The antidromic distal sensory latency of the superficial radial nerve was studied using 2 methods: (I) Recording from a major branch of a nerve as it crosses the extensor pollicis longus tendon, using segments of 10, 12, and 14cm; (II) Recording from the thumb, using segments of 14, 16, and 18cm. The mean latency, to ...
journal_title：Archives of physical medicine and rehabilitation
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
