Abstract:
:Indoor air pollution occurs as an undesirable consequence of urbanization, energy conservation, indoor bioaerosol contamination, and use of synthetic materials and new technologies, and has become a worldwide concern. It is important to comprehend not only the diversity of pollutant hazards but also to develop novel methods and approaches that establish dose-response relationships, cause-and-effect relationships, and clinical relevance. Coincident with heightened public concern over indoor air pollution and its health consequences, a revolution in immunology has occurred. The immune system is recognized as an essential defensive and homeostatic mechanism. Unfortunately, the immune apparatus is exquisitely sensitive to toxic damage. Equally important, among the disciplines available to assess the health impact of indoor air pollutants, immunology has the capability to provide sensitive and specific tools that may accurately measure relevant clinical effects at tissue, cellular, and molecular levels. Furthermore, exciting new insights into shared communications networks between the immune, endocrine, and central nervous systems may provide future explanations for the myriad human complaints associated with indoor air pollutants.
journal_name
Ann N Y Acad Scijournal_title
Annals of the New York Academy of Sciencesauthors
Brooks BO,Aldrich FD,Utter GM,DeBroy JA,Schimke RDdoi
10.1111/j.1749-6632.1992.tb16544.xsubject
Has Abstractpub_date
1992-04-30 00:00:00pages
199-214eissn
0077-8923issn
1749-6632journal_volume
641pub_type
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