Human immunodeficiency virus, pregnancy, and Stevens-Johnson syndrome.

Abstract:

BACKGROUND:Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening dermatologic disorders that are more common in the setting of a compromised immune system. We present the case of a pregnant patient with known human immunodeficiency virus (HIV) infection who presented with Stevens-Johnson syndrome after treatment with antibiotics for a urinary tract infection. CASE:A young woman at 33 4/7 weeks of gestation with known HIV infection presented to the emergency room with a chief complaint of rash, fever, blisters, and lower abdominal pain. Her symptoms were present for 2 days after ingestion of nitrofurantoin, prescribed for a urinary tract infection. She was diagnosed with preterm labor and possibly Stevens-Johnson syndrome. Due to active labor, HIV, and vaginal stenosis, a primary cesarean was performed. A skin biopsy performed at the time of admission confirmed the diagnosis of a drug-induced dermatosis (erythema multiforme), evidenced by subepidermal bullae, hemorrhage, and acantolated, dyskeratotic eosinophilic cells. CONCLUSION:Stevens-Johnson syndrome and toxic epidermal necrolysis represent a spectrum of disease that has been long associated with multiple drugs, recently including many antiretroviral medications. It also seems that the incidence of these conditions is increased in immunocompromised patients. We speculate that the combination of HIV and pregnancy in addition to antibiotic treatment, such as with nitrofurantoin, may induce Stevens-Johnson syndrome in patients with severely altered immune systems.

journal_name

Obstet Gynecol

authors

Shilad A,Predanic M,Perni SC,Houlihan C,Principe D

doi

10.1097/01.AOG.0000157766.49494.99

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

1254-6

issue

5 Pt 2

eissn

0029-7844

issn

1873-233X

pii

105/5/1254

journal_volume

105

pub_type

杂志文章
  • Uterine sarcoidosis potentially associated with interferon-alpha use for chronic hepatitis C infection.

    abstract:BACKGROUND:A regimen including interferon-alpha has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-alpha is a granulomatous pulmonary reaction. CASE:A unique case of uterine sarcoidosis associated with the use of i...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000157764.44292.aa

    authors: Tsiodras S,Drimala P,Stavreas N,Dachlythras M,Alamani AM,Naoum G

    更新日期:2005-05-01 00:00:00

  • The risk of repeating low birth weight and the role of prenatal care.

    abstract:OBJECTIVE:To estimate the influence of adequacy of prenatal care and other known risk factors on the risk of repeating low birth weight (LBW) (less than 2500 g). METHODS:This was a retrospective cohort study of women having two births in Washington state during 1984-1990, as recorded using linked birth certificate rec...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Raine T,Powell S,Krohn MA

    更新日期:1994-10-01 00:00:00

  • Bleeding pattern and endometrial changes during continuous combined hormone replacement therapy. The Ogen/Provera Study Group.

    abstract:OBJECTIVE:To establish the optimum oral daily dose of micronized medroxyprogesterone acetate, given in combination with a fixed oral dose of estrone (E1) sulfate as hormone replacement therapy, that provides endometrial protection and induces cessation of vaginal bleeding. METHODS:This multicenter, randomized, double-...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0029-7844(98)00038-6

    authors: Nand SL,Webster MA,Baber R,O'Connor V

    更新日期:1998-05-01 00:00:00

  • Pathology slide review in gynecologic oncology.

    abstract:OBJECTIVE:To analyze the diagnostic accuracy and alteration in treatment planning from interinstitution (different institution) pathologic consultation. METHODS:We reviewed pathologic reports from 720 referred patients. The diagnosis rendered from a gynecologic pathologist was compared with the original diagnosis. Dis...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00032-5

    authors: Santoso JT,Coleman RL,Voet RL,Bernstein SG,Lifshitz S,Miller D

    更新日期:1998-05-01 00:00:00

  • Symptomatic patients with an early viable intrauterine pregnancy: HCG curves redefined.

    abstract:OBJECTIVE:To analyze the change in serial human chorionic gonadotropin (hCG) levels in women symptomatic with pain or bleeding who presented with nondiagnostic ultrasonography but were ultimately confirmed to have a viable intrauterine pregnancy. METHODS:The rise in serial hCG measures were modeled over time, with the...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000128174.48843.12

    authors: Barnhart KT,Sammel MD,Rinaudo PF,Zhou L,Hummel AC,Guo W

    更新日期:2004-07-01 00:00:00

  • Cervical vasopressin compared with no premedication and blood loss during vaginal hysterectomy: a randomized controlled trial.

    abstract:OBJECTIVE:To compare blood loss, operative time, postoperative pain medication requirements, and complication rates in patients undergoing vaginal hysterectomy who were randomly assigned to receive preoperative intracervical vasopressin or no intracervical injection. METHODS:Fifty-eight women undergoing vaginal hyster...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0b013e3181954c44

    authors: Ascher-Walsh CJ,Capes T,Smith J,Michels A

    更新日期:2009-02-01 00:00:00

  • Postural changes can reduce leakage in women with stress urinary incontinence.

    abstract:OBJECTIVE:To assess the efficacy of postural changes, such as crossing the legs, in reducing urine leakage in women with stress urinary incontinence. METHODS:Sixty-five women with urodynamically proven stress incontinence underwent a series of standing cough stress tests in each of four postures: standing, crossing th...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Norton PA,Baker JE

    更新日期:1994-11-01 00:00:00

  • Endometrial carcinoma after endometrial resection for dysfunctional uterine bleeding.

    abstract:BACKGROUND:Endometrial destruction is an accepted conservative surgical approach for women with dysfunctional uterine bleeding. However, this procedure cannot guarantee complete removal of the entire endometrium. The possibility exists that endometrial carcinoma may develop even years after such procedure. CASE:We rep...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000160484.20261.fd

    authors: Sagiv R,Ben-Shem E,Condrea A,Glezerman M,Golan A

    更新日期:2005-11-01 00:00:00

  • Attitudes of mothers of children with Down syndrome concerning amniocentesis, abortion, and prenatal genetic counseling techniques.

    abstract::Mothers of children with Down syndrome were surveyed by questionnaire concerning their attitudes about amniocentesis, prenatal genetic counseling, and abortion. Of the 101 who responded, 40 had borne children after giving birth to a child with Down syndrome. Half had amniocentesis in subsequent pregnancies but only ha...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Elkins TE,Stovall TG,Wilroy S,Dacus JV

    更新日期:1986-08-01 00:00:00

  • Antepartum diagnosis of fetal intracranial hemorrhage due to maternal Bernard-Soulier syndrome.

    abstract:BACKGROUND:Bernard-Soulier syndrome, a lack of glycoprotein IB/IX, is a rare autosomal recessive bleeding disorder characterized by platelet dysfunction. Women with Bernard-Soulier syndrome are at risk of being immunized against glycoprotein IB/IX, leading to severe isoimmune neonatal thrombocytopenia. CASE:A 26-year-...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(99)00253-7

    authors: Fujimori K,Ohto H,Honda S,Sato A

    更新日期:1999-11-01 00:00:00

  • Extensive Tattoos Mimicking Lymphatic Metastasis on Positron Emission Tomography Scan in a Patient With Cervical Cancer.

    abstract:BACKGROUND:Positron emission tomography (PET) fused with computed tomography (CT) imaging is common in the clinical assessment of patients with locally advanced cervical cancer. Limitations to the utilization and interpretation of PET-CT scans in patients with cervical cancer have been described, including false-positi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000701

    authors: Grove N,Zheng M,Bristow RE,Eskander RN

    更新日期:2015-07-01 00:00:00

  • Transabdominal cerclage: a laparoscopic approach.

    abstract:BACKGROUND:The placement of a transabdominal cervical cerclage has been regarded as considerably more morbid than a transvaginal cerclage, in part due to the need for two laparotomies. We describe a technique for the laparoscopic placement and removal of a transabdominal cerclage. CASES:Two cases of women with insuffi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00655-8

    authors: Lesser KB,Childers JM,Surwit EA

    更新日期:1998-05-01 00:00:00

  • Nodal metastasis risk in endometrioid endometrial cancer.

    abstract:OBJECTIVE:To estimate the risk for nodal metastasis in women with endometrial cancer based on uterine characteristics on pathology. METHODS:From a study of staging for uterine cancer, women were identified as being at low risk for nodal metastasis based on three specific criteria on final pathology reports: 1) less th...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318240de51

    authors: Milam MR,Java J,Walker JL,Metzinger DS,Parker LP,Coleman RL,Gynecologic Oncology Group.

    更新日期:2012-02-01 00:00:00

  • Fetal injury associated with cesarean delivery.

    abstract:OBJECTIVE:To describe the incidence and type of fetal injury identified in women undergoing cesarean delivery. METHODS:Between January 1, 1999, and December 31, 2000, a prospective cohort study of all cesarean deliveries was conducted at 13 university centers. Information regarding maternal and infant outcomes was abs...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.AOG.0000237116.72011.f3

    authors: Alexander JM,Leveno KJ,Hauth J,Landon MB,Thom E,Spong CY,Varner MW,Moawad AH,Caritis SN,Harper M,Wapner RJ,Sorokin Y,Miodovnik M,O'Sullivan MJ,Sibai BM,Langer O,Gabbe SG,National Institute of Child Health and Human Deve

    更新日期:2006-10-01 00:00:00

  • Post-term birth: risk factors and outcomes in a 10-year cohort of Norwegian births.

    abstract:OBJECTIVE:To identify factors associated with post-term birth and factors associated with adverse outcomes in post-term births. METHODS:The sample was a 10-year cohort (1978-1987) of term (n = 379,445) and post-term (n = 65,796) births from the Medical Birth Registry of Norway. Gestational age was based on mothers' re...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00049-5

    authors: Campbell MK,Ostbye T,Irgens LM

    更新日期:1997-04-01 00:00:00

  • Economic burden of hospitalizations for preterm labor in the United States.

    abstract:OBJECTIVE:To determine patient factors associated with hospital care costs for preterm labor and to develop a clinically applicable cost model for evaluating economic consequences of interventions to reduce preterm-labor hospitalizations. METHODS:Maryland state hospital discharge data from 1993-1996 were used to ident...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)00863-2

    authors: Nicholson WK,Frick KD,Powe NR

    更新日期:2000-07-01 00:00:00

  • Effect of ritodrine on labor after premature rupture of the membranes.

    abstract::The effect on labor of administering ritodrine after a premature rupture of the membranes (PROM) was studied in a double-blind trial in 30 patients. The patients were selected according to the following criteria: 28 to 36 weeks' gestation, only 1 fetus, cervix dilated 4 cm or less, and absence of pyrexia or other sign...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Christensen KK,Ingemarsson I,Leideman T,Solum T,Svenningsen N

    更新日期:1980-02-01 00:00:00

  • Cloacal dysgenesis.

    abstract::Cloacal dysgenesis is a rare anomaly. Fifty cases have been reported in the literature. This condition differs from the usual imperforate anus. The diagnosis, evaluation, and therapeutic management require an understanding of the embryogenesis of the cloaca. The presence at birth of a single interlabial orifice or an ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Okonkwo JE,Crocker KM

    更新日期:1977-07-01 00:00:00

  • Ability of normal vaginal flora to produce detectable phosphatidylglycerol in amniotic fluid in vitro.

    abstract:OBJECTIVE:To determine if bacteria are capable of producing phosphatidylglycerol in amniotic fluid (AF) and the number of colony forming units (CFU) of bacteria necessary to produce this result. METHODS:Eleven species of bacteria and one species of yeast, common to the female genital tract and implicated in chorioamni...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00032-m

    authors: Lambers DS,Brady K,Leist PA,Setser C,Helmchen R

    更新日期:1995-05-01 00:00:00

  • Obstetric Care Consensus No. 4: Periviable Birth.

    abstract::Approximately 0.5% of all births occur before the third trimester of pregnancy, and these very early deliveries result in the majority of neonatal deaths and more than 40% of infant deaths. A recent executive summary of proceedings from a joint workshop defined periviable birth as delivery occurring from 20 0/7 weeks ...

    journal_title:Obstetrics and gynecology

    pub_type: 共识发展会议,杂志文章

    doi:10.1097/AOG.0000000000001483

    authors:

    更新日期:2016-06-01 00:00:00

  • Intrauterine growth retarded infants. Correlation of gestational age with maternal factors, mode of delivery, and perinatal survival.

    abstract::Fifty-eight infants of 3332 deliveries (1.7%) were found to be growth retarded (IGR) at birth. For purposes of analysis, the infants were divided into 2 groups according to gestational age at delivery: Group I infants were delivered between 38 and 43 weeks' gestation, and Group II infants were delivered between 28 and...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Perry CP,Harris RE,DeLemos RA,Null DM Jr

    更新日期:1976-08-01 00:00:00

  • Association of abnormal ovarian reserve parameters with a higher incidence of aneuploid blastocysts.

    abstract:OBJECTIVE:To estimate the relationship between hormonal parameters of diminished ovarian reserve and the incidence of aneuploid blastocysts. METHODS:This prospective cohort trial was performed in a private in vitro fertilization clinic. Three hundred seventy-two patients underwent in vitro fertilization with blastocys...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/aog.0b013e318278eeda

    authors: Katz-Jaffe MG,Surrey ES,Minjarez DA,Gustofson RL,Stevens JM,Schoolcraft WB

    更新日期:2013-01-01 00:00:00

  • Delayed Umbilical Cord Clamping After Birth: ACOG Committee Opinion, Number 814.

    abstract::Delayed umbilical cord clamping appears to be beneficial for term and preterm infants. In term infants, delayed umbilical cord clamping increases hemoglobin levels at birth and improves iron stores in the first several months of life, which may have a favorable effect on developmental outcomes. There is a small increa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000004167

    authors:

    更新日期:2020-12-01 00:00:00

  • Pregnancy after bromocriptine-induced reduction of an extrasellar prolactin-secreting pituitary macroadenoma.

    abstract::In patients with a large prolactin-secreting pituitary adenoma, a marked reduction in tumor size may be achieved with bromocriptine therapy. However, before consideration of pregnancy, surgical removal of the lesion usually is advised. A 36-year-old woman with a large extrasellar pituitary macroadenoma was treated wit...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198409001-00001

    authors: Goodman LA,Chang RJ

    更新日期:1984-09-01 00:00:00

  • Patient Experiences With Miscarriage Management in the Emergency and Ambulatory Settings.

    abstract:OBJECTIVE:To quantitatively and qualitatively describe the patient experience for clinically stable patients presenting with miscarriage to the emergency department (ED) or ambulatory clinics. METHODS:We present a subanalysis of a mixed-methods study from 2016 on factors that influence miscarriage treatment decision-m...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003571

    authors: Miller CA,Roe AH,McAllister A,Meisel ZF,Koelper N,Schreiber CA

    更新日期:2019-12-01 00:00:00

  • Scheduled hysterectomy for second-trimester abortion in a patient with placenta accreta.

    abstract:BACKGROUND:As cesarean deliveries increase, so does placenta accreta. There is little evidence regarding management of patients with known or suspected abnormal placentation seeking abortion. CASE:A medically complicated patient with evidence of placenta increta on magnetic resonance imaging presented for pregnancy te...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318194258c

    authors: Tocce K,Thomas VW,Teal S

    更新日期:2009-02-01 00:00:00

  • Definitions of Obstetric and Gynecologic Hospitalists.

    abstract::The obstetric hospitalist and the obstetric and gynecologic hospitalist evolved in response to diverse forces in medicine, including the need for leadership on labor and delivery units, an increasing emphasis on quality and safety in obstetrics and gynecology, the changing demographics of the obstetric and gynecologic...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/AOG.0000000000001235

    authors: McCue B,Fagnant R,Townsend A,Morgan M,Gandhi-List S,Colegrove T,Stosur H,Olson R,Meyer K,Lin A,Tessmer-Tuck J

    更新日期:2016-02-01 00:00:00

  • Vaginal hysterectomy as primary treatment of endometrial cancer in medically compromised women.

    abstract:OBJECTIVE:To study the survival, rates and patterns of recurrence, and perioperative morbidity in medically compromised women with endometrial cancer treated by primary vaginal hysterectomy. METHODS:Fifty-one patients with endometrial cancer treated initially by vaginal hysterectomy between 1977 and 1999 were identifi...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Chan JK,Lin YG,Monk BJ,Tewari K,Bloss JD,Berman ML

    更新日期:2001-05-01 00:00:00

  • Bioactivity of serum hCG in preeclampsia.

    abstract:OBJECTIVE:To compare hCG levels, obtained by biologic and immunologic means, in women with normal pregnancies and women with preeclampsia. METHODS:Peripheral blood samples from women in the third trimester with preeclampsia (n = 30) or normal pregnancies (n = 30) were assayed for immunoactive and bioactive hCG (mouse ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(01)01463-6

    authors: Casart YC,Camejo MI,Proverbio F,Febres F

    更新日期:2001-09-01 00:00:00

  • Postmenopausal bartholin gland enlargement: a hospital-based cancer risk assessment.

    abstract:OBJECTIVE:To assess the risk of Bartholin gland carcinoma in postmenopausal women. METHODS:A referral patient population from a tertiary care cancer center and a hospital-based regional tumor registry was used in a case-control and retrospective cohort study. We searched for data on any discharge diagnosis or procedur...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00404-1

    authors: Visco AG,Del Priore G

    更新日期:1996-02-01 00:00:00