Differential binding of oocyte-type and somatic-type 5S rRNA to TFIIIA and ribosomal protein L5 in Xenopus oocytes: specialization for storage versus mobilization.

abstract：:Collapsin-1 is a secreted glycoprotein that inhibits the extension of specific growth cones in vitro. It has been hypothesized to serve as a repulsive guidance cue for extending growth cones in vivo. Here we report the distribution of collapsin-1 message as demonstrated by in situ hybridization using digoxigenin-label...

journal_title：Developmental biology

authors： Shepherd I,Luo Y,Raper JA,Chang S

更新日期：1996-01-10 00:00:00

abstract：:Metamorphosis involves the destruction of larval, the formation of adult and the transformation of larval into adult tissues. In this study, we demonstrate the role of the Drosophila nuclear proteins EAST and Chromator in tissue destruction and remodeling. To better understand the function of east, we performed a yeas...

journal_title：Developmental biology

authors： Wasser M,Bte Osman Z,Chia W

更新日期：2007-07-15 00:00:00

abstract：:Cells anchor to substrates by binding to extracellular matrix (ECM). In addition to this anchoring function however, cell-ECM binding is a mechanism for cells to sense their surroundings and to communicate and coordinate behaviour amongst themselves. Several ECM molecules and their receptors play essential roles in mu...

journal_title：Developmental biology

authors： Thorsteinsdóttir S,Deries M,Cachaço AS,Bajanca F

更新日期：2011-06-15 00:00:00

abstract：:These studies were designed to test the hypothesis that sperm nuclear decondensation and male pronuclear formation during hamster fertilization depend upon the ability of the fertilized oocyte to reduce sperm nuclear disulfide bonds. In a first series of experiments, treatment of mature oocytes with the sulfhydryl blo...

journal_title：Developmental biology

authors： Perreault SD,Wolff RA,Zirkin BR

更新日期：1984-01-01 00:00:00

abstract：:Primary sensory olfactory neurons reside in a neuroepithelium lining the nasal cavity and project topographically onto the surface of the olfactory bulb, a rostral extension of the telencephalon. Galectin-1, a bivalent galactose-binding vertebrate lectin, is expressed in the developing rodent olfactory system. In the ...

journal_title：Developmental biology

authors： Puche AC,Poirier F,Hair M,Bartlett PF,Key B

更新日期：1996-10-10 00:00:00

abstract：:Type II collagen is a major component of cartilage extracellular matrix. Differentiation of mesenchyme into cartilage involves the cessation of type I collagen synthesis and the onset of type II collagen synthesis. Solution hybridization of mRNA isolated from chick limb buds with a cDNA probe to type II collagen mRNA ...

journal_title：Developmental biology

authors： Swalla BJ,Upholt WB,Solursh M

更新日期：1988-01-01 00:00:00

abstract：:Cyclic protein-2 (CP-2) is secreted in vitro in substantial amounts by mature rat Sertoli cells in intact Stage VI and Stage VII seminiferous tubules. This stage-dependent secretion has led us to postulate that the biosynthesis of this molecule is stimulated by germ cells at a specific state of development. In order t...

journal_title：Developmental biology

authors： Wright WW

更新日期：1988-11-01 00:00:00

abstract：:Neural crest cells migrate extensively through a complex extracellular matrix (ECM) to sites of terminal differentiation. To determine what role the various components of the ECM may play in crest morphogenesis, quail (Coturnix coturnix japonica) neural crest cells have been cultured in three-dimensional hydrated coll...

journal_title：Developmental biology

authors： Tucker RP,Erickson CA

更新日期：1984-08-01 00:00:00

abstract：:Distinct groups of dopaminergic neurons develop at defined anatomical sites in the brain to modulate function of a large diversity of local and far-ranging circuits. However, the molecular identity as judged from transcription factor expression has not been determined for all dopaminergic groups. Here, we analyze regi...

journal_title：Developmental biology

authors： Filippi A,Jainok C,Driever W

更新日期：2012-09-01 00:00:00

abstract：:The Hedgehog (Hh) signal transduction pathway plays a central role in the development of invertebrates and vertebrates. While much is known about the pathway, the role of Suppressor of fused (Su(fu)), a component of the pathway's signaling complex has remained enigmatic. Previous studies have linked Su(fu) to the cyto...

journal_title：Developmental biology

authors： Sisson BE,Ziegenhorn SL,Holmgren RA

更新日期：2006-06-01 00:00:00

abstract：:The mature heart valves and septa are derived from the cardiac cushions which initially form as local outgrowths of mesenchymal cells within the outflow tract and atrioventricular regions. Endocardial cells respond to signals from the overlying myocardium and undergo an epithelial-to-mesenchymal transformation to inva...

journal_title：Developmental biology

authors： Kim RY,Robertson EJ,Solloway MJ

更新日期：2001-07-15 00:00:00

abstract：:Although local epithelial-mesenchymal tissue interactions which are presumably mediated by extracellular matrix molecules are important regulators of tooth morphogenesis and differentiation, our studies have indicated that these developmental processes also depend on circulating molecules. The iron-carrying serum prot...

journal_title：Developmental biology

authors： Partanen AM,Ekblom P,Thesleff I

更新日期：1985-09-01 00:00:00

abstract：:Experiments in which the developing gut of avian embryos was back-transplanted to permit the bowel to interact with the developing neural tube were undertaken. Segments of intestine from 4-day quail embryos were implanted between the somites and neural tubes of chick embryos of 7 to 24 somites. The spinal cord respond...

journal_title：Developmental biology

authors： Rothman TP,Gershon MD,Fontaine-Pérus JC,Chanconie M,Le Douarin NM

更新日期：1987-12-01 00:00:00

abstract：:Mutations in the Bone Morphogenetic Protein (BMP) pathway are associated with a range of defects in skeletal formation. Genetic analysis of BMP signaling requirements is complicated by the presence of three partially redundant BMPs that are required for multiple stages of limb development. We generated an inducible al...

journal_title：Developmental biology

authors： Norrie JL,Lewandowski JP,Bouldin CM,Amarnath S,Li Q,Vokes MS,Ehrlich LIR,Harfe BD,Vokes SA

更新日期：2014-09-15 00:00:00

abstract：:Cdc42, a member of the Rho family of GTP binding proteins, functions in the formation of polarized actin structures, in elongation of cell shape, and in cell signaling. Although genetic mutations previously have not been available in multicellular organisms, studies have attempted to discern Cdc42 functions in organis...

journal_title：Developmental biology

authors： Genova JL,Jong S,Camp JT,Fehon RG

更新日期：2000-05-01 00:00:00

abstract：:Many organisms both undergo dramatic morphological changes during post-embryonic development and also regenerate lost structures, but the roles of epigenetic regulators in such processes are only beginning to be understood. In the present study, the functions of two histone modifiers were examined during metamorphosis...

journal_title：Developmental biology

authors： Chou J,Ferris AC,Chen T,Seok R,Yoon D,Suzuki Y

更新日期：2019-06-01 00:00:00

abstract：:The regeneration of lost body parts is a fascinating phenomenon exhibited by some multicellular organisms. In social amoebae, such as Dictyostelium discoideum, the pseudoplasmodium is a temporary migratory multicellular structure with high regeneration ability. It consists of future stalk cells (prestalk cells) at the...

journal_title：Developmental biology

authors： Mohri K,Tanaka R,Nagano S

更新日期：2020-01-01 00:00:00

abstract：:We recently demonstrated the requirement of two-pore channel type 2 (TPC2)-mediated Ca2+ release during slow muscle cell differentiation and motor circuit maturation in intact zebrafish embryos. However, the upstream trigger(s) of TPC2/Ca2+ signaling during these developmental processes remains unclear. Nicotinic acid...

journal_title：Developmental biology

authors： Kelu JJ,Webb SE,Galione A,Miller AL

更新日期：2019-01-15 00:00:00

abstract：:Fertilization triggers activation of Src-family kinases in eggs of various species including marine invertebrates and lower vertebrates. While immunofluorescence studies have localized Src-family kinases to the plasma membrane or cortical cytoplasm, no information is available regarding the extent to which these kinas...

journal_title：Developmental biology

authors： Sharma D,Kinsey WH

更新日期：2006-07-15 00:00:00

abstract：:G protein Galpha subunits contribute to the specificity of different signal transduction pathways in Dictyostelium discoideum but Galpha subunit-effector interactions have not been previously identified. The requirement of the Dictyostelium Galpha4 subunit for MAP kinase (MAPK) activation and the identification of a p...

journal_title：Developmental biology

authors： Nguyen HN,Hadwiger JA

更新日期：2009-11-15 00:00:00

abstract：:Recent studies with amoebae of the Myxomycetes Didymium iridis and Physarum polycephalum reveal that competence to undergo sexual fusion or to differentiate to plasmodia apogamically can be induced by a diffusible factor. Suspension cultures of Didymium amoebae have proven to be a good source of the inducer activity. ...

journal_title：Developmental biology

authors： Nader WF,Shipley GL,Huettermann A,Holt CE

更新日期：1984-06-01 00:00:00

abstract：:DNA replication and its connection to M phase restraint are studied extensively at the level of single cells but rarely in the context of a developing animal. C. elegans lin-6 mutants lack DNA synthesis in postembryonic somatic cell lineages, while entry into mitosis continues. These mutants grow slowly and either die...

journal_title：Developmental biology

authors： Korzelius J,The I,Ruijtenberg S,Portegijs V,Xu H,Horvitz HR,van den Heuvel S

更新日期：2011-02-15 00:00:00

abstract：:Stimulation of epithelial cell cycling by the neuropeptide head activator was analyzed in Hydra magnipapillata and compared with the action of head activator on bud formation and tentacle formation during head regeneration. The results obtained indicate that head activator treatment stimulates epithelial cell division...

journal_title：Developmental biology

authors： Hobmayer B,Holstein TW,David CN

更新日期：1997-03-01 00:00:00

abstract：:A series of chimeras was generated by injecting single normal, parthenogenetic, or androgenetic blastomeres carrying transgenic markers under the zona pellucida of nontransgenic eight-cell embryos. These chimeras were cultured to the blastocyst stage and sectioned, and the transgenic component was detected by in situ ...

journal_title：Developmental biology

authors： Thomson JA,Solter D

更新日期：1989-02-01 00:00:00

abstract：:We have compared the ability of uncapacitated, capacitated acrosome intact, and acrosome-reacted hamster sperm to penetrate the cumulus and corona radiata of fresh hamster oocyte-cumulus complexes (OCC) in vitro. This was done using physiological numbers (1-20) of sperm so that cumulus and corona radiata cells did not...

journal_title：Developmental biology

authors： Corselli J,Talbot P

更新日期：1987-07-01 00:00:00

abstract：:The nuclear lamina is an extensive protein network that underlies the inner nuclear envelope. This network includes the LAP2-emerin-MAN1-domain (LEM-D) protein family, proteins that share an association with the chromatin binding protein Barrier-to-autointegration factor (BAF). Loss of individual LEM-D proteins causes...

journal_title：Developmental biology

authors： Barton LJ,Lovander KE,Pinto BS,Geyer PK

更新日期：2016-07-01 00:00:00

abstract：:When a posterior fragment of the chick's marginal zone (PM) was exchanged with equal sized lateral marginal zone fragment (LM), of the same blastoderm, its capacity to initiate an ectopic primitive streak (PS) was found to be both size and stage dependent. Good correlation was demonstrated between the areas of PM frag...

journal_title：Developmental biology

authors： Eyal-Giladi H,Khaner O

更新日期：1989-07-01 00:00:00

abstract：:We have examined the response of bovine oocytes matured in vitro for 24 hr to parthenogenic activation using compounds that increase intracellular calcium (ionomycin) or inhibit protein phosphorylation (6-dimethylaminopurine, DMAP). Treatment with ionomycin alone caused resumption of meiosis (57.8 +/- 7.8%) but not pr...

journal_title：Developmental biology

authors： Susko-Parrish JL,Leibfried-Rutledge ML,Northey DL,Schutzkus V,First NL

更新日期：1994-12-01 00:00:00

abstract：:Little is known about the genetic basis of behavioral choice, such as temperature preference, especially in natural populations. Thermal preference can play a key role in habitat selection, for example in aquatic species. Examining this behavior on a genetic level requires access to individuals or populations of the s...

journal_title：Developmental biology

authors： Tabin JA,Aspiras A,Martineau B,Riddle M,Kowalko J,Borowsky R,Rohner N,Tabin CJ

更新日期：2018-09-15 00:00:00

abstract：:In this report we describe the development of a sensitive assay for gene expression in zebrafish embryos using beta-lactamase as a reporter gene. We show that injection of a green fluorescent substrate for beta-lactamase allows the detection of reporter gene expression in live embryos. The beta-lactamase enzyme cataly...

journal_title：Developmental biology

authors： Raz E,Zlokarnik G,Tsien RY,Driever W

更新日期：1998-11-15 00:00:00