Abstract:
PURPOSE:To describe the techniques and results of perfluoro-N-octane used during vitrectomy for managing retinal detachment with severe proliferative vitreoretinopathy (PVR). METHODS:The authors retrospectively studied 223 consecutive patients who underwent vitreoretinal surgery for severe PVR (93% D1-D3). Patients underwent an average of 1.72 prior vitreoretinal surgeries. Perfluoro-N-octane was used intraoperatively to flatten the retina, avoiding posterior drainage retinotomy, to identify areas of residual retinal traction and periretinal membranes, to stabilize the peripheral retina during dissection of anterior PVR, and to help determine the extent and location of relaxing retinotomies. Extended-term gas tamponade was used in 91% of eyes. All patients were followed for a minimum of 6 months. RESULTS:Seventy-eight percent of the retinas were reattached posterior to the scleral buckle after a single vitreoretinal surgery and 96% were reattached after multiple surgeries. An average of 1.24 vitrectomy surgeries were required. The final visual acuity was 20/400 or better in 74% of eyes and 20/80 or better in 30% (P = 0.004). Preoperative hypotony (intraocular pressure < or = 5 mmHg) and multiple prior vitreoretinal surgeries were associated with a poor final visual acuity (P = 0.01 and 0.02, respectively). Preoperative hypotony (intraocular pressure < or = 5 mmHg) was associated with a greater frequency of relaxing retinotomies (P = 0.02). Retained perfluoro-N-octane was observed postoperatively in the vitreous cavity in 1.3% and subretinal perfluoro-N-octane in 0.9%. CONCLUSION:Experience with perfluoro-N-octane has demonstrated its usefulness both diagnostically and therapeutically as an intraoperative tool and improved the anatomic and visual outcome for retinal detachment complicated by severe PVR.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Coll GE,Chang S,Sun J,Wieland MR,Berrocal MHdoi
10.1016/s0161-6420(95)30975-xsubject
Has Abstractpub_date
1995-04-01 00:00:00pages
630-8; discussion 638-9issue
4eissn
0161-6420issn
1549-4713pii
S0161-6420(95)30975-Xjournal_volume
102pub_type
杂志文章相关文献
OPHTHALMOLOGY文献大全abstract::A computer program designed according to the needs of clinical investigators has recently been implemented. This ambitious undertaking allows the ophthalmologist direct interfacing and control over all his data, presently 3,252 diabetic patient records, and thus harnesses his hypothesis-testing intuitions with the mem...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34974-4
更新日期:1981-07-01 00:00:00
abstract:PURPOSE:To assess visual acuity impairment in Stargardt disease. DESIGN:Retrospective clinic-based cross-sectional study. PARTICIPANTS:Three-hundred sixty-one patients with Stargardt disease. METHODS:Clinical findings in 361 patients were analyzed as part of a cross-sectional evaluation. Visual acuity at their most ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(03)00333-6
更新日期:2003-06-01 00:00:00
abstract:PURPOSE:To evaluate the performance of retinal specialists in detecting retinal fluid presence in spectral domain OCT (SD-OCT) scans from eyes with age-related macular degeneration (AMD) and compare performance with an artificial intelligence algorithm. DESIGN:Prospective comparison of retinal fluid grades from human ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2020.06.038
更新日期:2021-01-01 00:00:00
abstract::Five hundred forty-seven reports of adverse reactions to timolol maleate received by the National Registry for Drug-induced Ocular Side Effects during an eleven-month period were reviewed. Approximately half the reports concerned systemic reactions affecting the cardiac, pulmonary, central nervous, gastrointestinal, a...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35215-9
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVE:The aims of this study were to describe the clinical features and biometric findings in the eyes of children with coloboma and to develop a classification of coloboma that correlates with visual function. DESIGN:Retrospective observational case series. PARTICIPANTS:One hundred thirteen children and young ad...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(99)00140-2
更新日期:2000-03-01 00:00:00
abstract::A case of preseptal cellulitis caused by Mycobacterium intracellulare is presented. A 56-year-old white woman developed erythema, induration, and tenderness of the lids of her right eye after chalazion removal, which did not respond to three weeks of broad spectrum antibiotics. Incision and drainage with biopsy reveal...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(82)34762-4
更新日期:1982-05-01 00:00:00
abstract::Ten patients had large recession of four horizontal recti at one procedure for treatment of nystagmus. Six patients had congenital motor nystagmus, two had oculocutaneous albinism, and two had optic nerve hypoplasia. Anomalous head posture with null point was also present in five patients. The rectus muscles were plac...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(91)32139-0
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:Dislocation of nuclear lens fragments during phacoemulsification can lead to a high incidence of glaucoma, uveitis, and poor visual acuity. The correct approach to these patients is uncertain. The authors report on eight patients who underwent pars plana vitrectomy with removal of lens fragments. METHODS:Ch...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(92)31805-6
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVE:To characterize the clinical features of ocular Whipple's disease (WD) and determine the long-term prognosis after antibiotic treatment. DESIGN:Retrospective case series. PARTICIPANTS:Medical records of patients referred between January 1993 and December 2010 were reviewed for chronic corticosteroid-resista...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.01.024
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Transconjunctival cryopexy of the vitreous base is clinically effective in patients with steroid nonresponsive pars planitis who have peripheral neovascularization. Cryoablation of the region previously has been thought to eliminate the areas of permeable neovascular tissue, thus removing the focus of exudat...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(13)31726-6
更新日期:1994-07-01 00:00:00
abstract:PURPOSE:To test a linear model relating the regional loss in retinal nerve fiber (RNFL) thickness to the corresponding regional loss in sensitivity with data from patients with previous anterior ischemic optic neuropathy (AION). DESIGN:Case-control study. PARTICIPANTS:Twenty-four individuals with AION and 20 with nor...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2007.06.001
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To evaluate the visual and refractive outcome of corneal transplant surgery, cataract extraction, and intraocular lens (IOL) implantation in children with traumatic corneal laceration and cataract. DESIGN:Retrospective, noncomparative case series. PARTICIPANTS:Five patients, 7 years of age or younger, who u...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(00)00524-8
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVE:To estimate the age- and gender-specific prevalence of posterior subcapsular (PSC), nuclear, cortical, and mixed lens opacities in a population-based sample of Latinos 40 years and older. DESIGN:Population-based, cross-sectional study. PARTICIPANTS:Six thousand three hundred fifty-seven Latinos 40 years and...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.01.024
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVE:Central retinal vein occlusion (CRVO) is a vision-threatening disease, primarily occurring among patients aged more than 60 years. Several risk factors, including arterial hypertension and diabetes mellitus, have been identified. Compression of the central retinal vein by an atherosclerotic retinal artery at ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2010.10.014
更新日期:2011-06-01 00:00:00
abstract::Sixty-four consecutive patients with aphakic penetrating keratoplasty and penetrating keratoplasty combined with intracapsular cataract extraction were reviewed in a prospective fashion with a minimum of a one-year follow-up. Five were lost to follow-up. There were seven graft failures at the end of one year. Five of ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(80)35187-7
更新日期:1980-07-01 00:00:00
abstract::We studied the macrostructural characteristics of papillary changes of the upper tarsal conjunctiva associated with the wearing of polymethyl methacrylate (PMMA) contact lenses. Fifty subjects with elevated conjunctival papillae greater than 0.3 mm in diameter were studied. Macrostructural characteristics recorded wer...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(81)34899-4
更新日期:1981-11-01 00:00:00
abstract:PURPOSE:To evaluate and correlate findings obtained by optical coherence tomography (OCT) imaging with visual acuity (VA) and macular lesions in patients with X-linked retinoschisis (XLRS). DESIGN:Prospective comparative case series. PARTICIPANTS:Thirty-one patients with confirmed XLRS. METHODS:Best-corrected VA was...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2004.08.027
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:A trabeculectomy is frequently combined with extracapsular cataract surgery to minimize the risks of further optic nerve damage associated with intraocular pressure (IOP) elevations after cataract surgery in eyes with glaucoma. Acute IOP elevations still occur after this combined surgery. The author evaluated t...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(93)31603-9
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:To report the effects of intravenous immunoglobulin treatment of ten patients with progressive ocular cicatricial pemphigoid who did not respond to conventional immunomodulatory regimens. DESIGN:Noncomparative, interventional case series. PARTICIPANTS:Ten patients with biopsy-proven progressive cicatricial ...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/S0161-6420(99)90496-7
更新日期:1999-11-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of alcohol delamination in the management of recurrent corneal erosions (RCEs). DESIGN:Prospective single-center consecutive descriptive case series. PARTICIPANTS:Twelve patients with RCEs who did not respond to conservative management were treated with alcohol delamination. METHO...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ophtha.2005.10.049
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To determine whether ocular cicatricial pemphigoid (OCP) may represent a distinct immunopathologic disease when it is pure ocular cicatricial pemphigoid (POCP) (e.g., only confined to the conjunctiva) or when it is associated with skin or extraocular mucous membrane lesions or both (OCP+). DESIGN:Prospective...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/S0161-6420(99)90076-3
更新日期:1999-02-01 00:00:00
abstract:OBJECTIVE:To quantify the relationship between myopia and open-angle glaucoma, ocular hypertension (OH), and intraocular pressure (IOP) in a representative older population. DESIGN:Cross-sectional population-based study of 3654 Australians 49 to 97 years of age. METHODS:Subjects with any myopia (> or =-1.0 diopter [D...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(99)90416-5
更新日期:1999-10-01 00:00:00
abstract:PURPOSE:To report the 4-year outcomes of corneal cross-linking (CXL) for progressive keratoconus in a population of different age groups. DESIGN:Retrospective, single-center, nonrandomized clinical study. PARTICIPANTS:Four hundred consecutive eyes treated with corneal CXL for progressive keratoconus from April 2006 t...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2012.10.023
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To investigate whether artificial tears and cold compress alone or in combination provide a treatment benefit and whether they were as effective as or could enhance topical antiallergic medication. DESIGN:Randomized, masked clinical trial. PARTICIPANTS:Eighteen subjects (mean age, 29.5±11.0 years) allergic ...
journal_title:Ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ophtha.2013.08.007
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To investigate the genetic causes of complete and incomplete achromatopsia (ACHM) and assess the association between disease-causing mutations, phenotype at diagnosis, and visual prognosis. DESIGN:Clinic-based, longitudinal, multicenter study. PARTICIPANTS:Probands with complete ACHM (n = 35), incomplete AC...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2009.03.053
更新日期:2009-10-01 00:00:00
abstract::The clinical efficacy was investigated of fibronectin eyedrops on the nonhealing corneal epithelial defect after herpetic keratitis. Fibronectin eyedrops were prepared from the patient's own blood plasma by an affinity chromatography using gelatin-coupled agarose gel and by gel filtration technique. Twenty eyes with m...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/s0161-6420(85)34050-2
更新日期:1985-02-01 00:00:00
abstract:PURPOSE:To determine whether migraine is associated with an increased risk of developing ocular motor cranial nerve palsies (OMCNP). DESIGN:Nationwide retrospective cohort study. PARTICIPANTS:Medical records of patients with migraine who were entered in the National Health Insurance Research Database (NHIRD) between ...
journal_title:Ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ophtha.2015.09.003
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:Correctable vision impairment caused by refractive error is common in the United States population. We estimated the direct costs of providing eyeglasses to all Americans (age> or =12) who need refractive correction to achieve good distance vision. DESIGN:Cross-sectional study of a nationally representative ...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2006.06.033
更新日期:2006-12-01 00:00:00
abstract:PURPOSE:A study was performed to determine if diabetic subjects who fail to respond to initial panretinal photocoagulation with regression of retinopathy risk factors do better with supplemental panretinal photocoagulation. METHODS:Thirty-five patients with 3 or more retinopathy risk factors who failed to respond to p...
journal_title:Ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0161-6420(92)31739-7
更新日期:1992-11-01 00:00:00
abstract:PURPOSE:To use optical coherence tomography (OCT) to evaluate the femtosecond laser intrastromal incisions made during cataract surgery to reduce corneal astigmatism. DESIGN:Retrospective case series. PARTICIPANTS:Seventy-seven eyes of 77 patients. METHODS:Paired intrastromal incisions were created using the Catalys...
journal_title:Ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ophtha.2017.03.022
更新日期:2017-08-01 00:00:00