Abstract:
:The relationship between myocardial contrast echocardiography and improvement of the left ventricular wall motion was studied as an indicator of the prognosis of patients with acute myocardial infarction. Ten patients with acute anterior myocardial infarction who demonstrated successful reperfusion (improved to TIMI grade III) and patency of the responsible coronary artery during the chronic stage (one month after the onset) were selected. The contrast study used 2 ml of sonicated iopamidol injected into the left coronary artery. Two-dimensional echocardiograms were taken at the level of papillary muscle on the short axis for recording in VTR. The results of the contrast study were evaluated using a contrast defect score based on the degree and width of the contrast defect. Percent wall motion improvement was measured as an index of improvement of the left ventricular wall motion and CKmax was used for estimating the extent of myocardial necrosis. There was a good correlation between contrast defect score and CKmax (r = 0.853) or % wall motion improvement (r = 0.77). No correlation was found between coronary occlusion time and CKmax nor between coronary occlusion time and % wall motion improvement. The results suggest that if the score is high, recovery of left ventricular wall motion cannot be expected in patients with acute myocardial infarction who demonstrate successful reperfusion. In such cases, myocardial perfusion has not been effectively restored and myocardial necrosis extended over a wide area. If the score is low, recovery of the wall motion can be expected in the chronic stage even though abnormal left ventricular wall motion area is extensive immediately after reperfusion therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Cardioljournal_title
Journal of cardiologyauthors
Nishizaki S,Ohke M,Masaoka Y,Mohri S,Mikouchi H,Nishizaki Ysubject
Has Abstractpub_date
1995-03-01 00:00:00pages
105-12issue
3eissn
0914-5087issn
1876-4738journal_volume
25pub_type
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更新日期:2007-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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journal_title:Journal of cardiology
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doi:
更新日期:2006-06-01 00:00:00
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doi:
更新日期:2005-05-01 00:00:00
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更新日期:1987-06-01 00:00:00
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journal_title:Journal of cardiology
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更新日期:1997-01-01 00:00:00
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pub_type: 杂志文章
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