The cerebral hemodynamics of normotensive hypovolemia during lower-body negative pressure.

Abstract:

:Although severe hypovolemia can lead to hypotension and neurological decline, many patients with neurosurgical disorders experience a significant hypovolemia while autonomic compensatory mechanisms maintain a normal blood pressure. To assess the effects of normotensive hypovolemia upon cerebral hemodynamics, transcranial Doppler ultrasound monitoring of 13 healthy volunteers was performed during graded lower-body negative pressure of up to -50 mm Hg, an accepted laboratory model for reproducing the physiological effects of hypovolemia. Middle cerebral artery flow velocity declined by 16% +/- 4% (mean +/- standard error of the mean) and the ratio between transcranial Doppler ultrasound pulsatility and systemic pulsatility rose 22% +/- 8%, suggesting cerebral small-vessel vasoconstriction in response to the sympathetic activation unmasked by lower-body negative pressure. This vasoconstriction may interfere with the autoregulatory response to a sudden fall in blood pressure, and may explain the common observation of neurological deficit during hypovolemia even with a normal blood pressure.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Giller CA,Levine BD,Meyer Y,Buckey JC,Lane LD,Borchers DJ

doi

10.3171/jns.1992.76.6.0961

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

961-6

issue

6

eissn

0022-3085

issn

1933-0693

journal_volume

76

pub_type

杂志文章
  • The surgical correction of coronal and metopic craniosynostoses.

    abstract::Procedures for relief of coronal synostosis and metopic synostosis have resulted in some undesirable sequelae. The authors present combined neurological and plastic surgical modifications to prevent additional synostoses, forehead ridging, and lateral orbital wall step-off. They recommend bifrontal craniotomy with lat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1983.59.2.0245

    authors: Marsh JL,Schwartz HG

    更新日期:1983-08-01 00:00:00

  • Relationship between transcranial Doppler-determined pulsatility index and cerebrovascular resistance: an experimental study.

    abstract::Clinical studies with transcranial Doppler suggest that the pulsatility of the flow velocity (FV) waveform increases when the distal cerebrovascular resistance (CVR) increases. To clarify this relationship, the authors studied animal models in which the resistance may be decreased in a controlled manner by an increase...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1996.84.1.0079

    authors: Czosnyka M,Richards HK,Whitehouse HE,Pickard JD

    更新日期:1996-01-01 00:00:00

  • The "thousand-hands Kannon" universal headframe. Technical note.

    abstract::The authors describe a new headframe system, by which a variety of instruments, such as brain retractors, suction tubes, mirrors, forks, armrests, and cotton-sheet trays, can be simultaneously supported. This frame enables neurosurgeons to perform operations with greater ease and fewer problems. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.71.6.0945

    authors: Tamaki N,Ehara K,Matsumoto S

    更新日期:1989-12-01 00:00:00

  • Gamma Knife surgery of vestibular schwannomas: longitudinal changes in vestibular function and measurement of the Dizziness Handicap Inventory.

    abstract:OBJECT:Gamma Knife surgery (GKS) is one of the methods available to treat vestibular schwannomas (VSs), in addition to microsurgical resection; however, clear information regarding balance function outcomes and the impact of treatment on patients' quality of life over time remains an important clinical need. The purpos...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS/2008/109/12/S21

    authors: Wackym PA,Hannley MT,Runge-Samuelson CL,Jensen J,Zhu YR

    更新日期:2008-12-01 00:00:00

  • Chronic diploic hematoma of the parietal bone. Case report.

    abstract::A case of chronic diploic hematoma of the parietal bone is reported. This lesion is considered to have developed over several years following minor head trauma. Clinical, radiological, and pathological findings of this rare lesion are described. To the authors' knowledge, this is the first reported case of such an unc...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1994.80.6.1112

    authors: Sato K,Kubota T,Kawano H

    更新日期:1994-06-01 00:00:00

  • Definition of cellular immune responses to brain antigens in human head trauma.

    abstract::Cellular immune responses to brain antigens in patients with head injury were studied by applying the leukocyte adherence inhibition (LAI) assay. The investigation was conducted in three phases. 1) In the initial phase, evaluation of a series of 22 test and 25 control cases obtained at random during a 2- to 6-week tim...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1979.51.3.0317

    authors: Apuzzo ML,Sheikh KM,Heiden JS,Weiss MH,Kurze T

    更新日期:1979-09-01 00:00:00

  • Synergistic effect of basic fibroblast growth factor and methylprednisolone on neurological function after experimental spinal cord injury.

    abstract::The authors evaluated the effects of exogenous basic fibroblast growth factor (bFGF) in combination with intravenous methylprednisolone on neurological function and cord angiogenesis in a model of spinal cord injury. Cord injury was produced by extradural clip compression through a T-1 laminectomy. Rats were randomize...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1995.83.1.0105

    authors: Baffour R,Achanta K,Kaufman J,Berman J,Garb JL,Rhee S,Friedmann P

    更新日期:1995-07-01 00:00:00

  • Selective peripancreatic sarcoma metastases from primary gliosarcoma. Case report.

    abstract::Two phenomena associated with malignant gliomas are: 1) the ability to metastasize systemically, and 2) the capacity to induce sarcomatous transformation within the supportive mesenchyma. An unusual case is presented of selective metastases of the sarcomatous elements of a mixed gliosarcoma. Immunohistochemical cell s...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1984.61.3.0599

    authors: Weaver D,Vandenberg S,Park TS,Jane JA

    更新日期:1984-09-01 00:00:00

  • Chronic demeclocycline therapy in the syndrome of inappropriate ADH secretion due to brain tumor.

    abstract::The treatment of the syndrome of chronic inappropriate antidiuretic hormone (ADH) secretion by fluid restriction is often attended by poor patient compliance. The following case report illustrates successful management of this condition by oral demeclocycline therapy in a patient who had hyponatremia in association wi...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1977.47.6.0933

    authors: Graze K,Molitch ME,Post K

    更新日期:1977-12-01 00:00:00

  • Choroid plexus carcinoma presenting as an intraparenchymal mass.

    abstract::A 6-year-old girl with a history of a nondisplaced skull fracture diagnosed with computerized tomography (CT) scanning 3 years previously presented with a 6-week history of headaches and decreased use of her right side. On admission CT scans, a large cystic mass was identified in the left frontal lobe region of the br...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审

    doi:10.3171/jns.2001.95.6.1040

    authors: Carter AB,Price DL Jr,Tucci KA,Lewis GK,Mewborne J,Singh HK

    更新日期:2001-12-01 00:00:00

  • The sympathetic nervous system and atherosclerosis.

    abstract::Morphometric and chemical changes in the arterial wall were studied after 12 months of diet-induced atherosclerosis in rhesus monkeys treated with either bilateral surgical thoracic sympathectomy or propranolol. There was a marked reduction in the progression of atherosclerosis in the carotid arteries and a moderate r...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1987.67.6.0906

    authors: Lichtor T,Davis HR,Johns L,Vesselinovitch D,Wissler RW,Mullan S

    更新日期:1987-12-01 00:00:00

  • Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients.

    abstract:OBJECT:The authors reviewed their experience with endoscopic approaches to determine their safety and efficacy in the treatment of pediatric patients who harbor skull base lesions. Although they were interested in ascertaining outcomes after surgery as well as validating and defining indications and limitations of thes...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2007.106.2.75

    authors: Kassam A,Thomas AJ,Snyderman C,Carrau R,Gardner P,Mintz A,Kanaan H,Horowitz M,Pollack IF

    更新日期:2007-02-01 00:00:00

  • Supraophthalmic carotid infusion for brain-tumor chemotherapy. Technical note.

    abstract::The ocular complications of intracarotid infusion of drugs for brain-tumor chemotherapy may be eliminated by infusion of the chemotherapeutic agent into the carotid artery above the origin of the ophthalmic artery. The authors have developed a catheter that can negotiate the carotid siphon. This catheter is not balloo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1983.58.4.0616

    authors: Kapp JP,Ross RL,Tucker EM

    更新日期:1983-04-01 00:00:00

  • Malignant triton tumor of the acoustic nerve. Case report.

    abstract::The authors present the clinical, radiological, pathological features, and autopsy findings of a patient with malignant triton tumor of the acoustic nerve, which probably arose from a pre-existing acoustic schwannoma. The term "malignant triton tumor" is applied to malignant schwannomas with rhabdomyoblastic different...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1992.76.5.0874

    authors: Han DH,Kim DG,Chi JG,Park SH,Jung HW,Kim YG

    更新日期:1992-05-01 00:00:00

  • Comparison of CT-guided and stereotaxic cranial diagnostic needle biopsies.

    abstract::Needle biopsy of the brain utilizing computerized tomography (CT) scan data is an accepted diagnostic technique that has been performed both with and without the aid of stereotaxic frames. Experience with both techniques has resulted in a specific procedure for CT-guided free-hand biopsy which is performed in the CT s...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1987.67.3.0341

    authors: Goldstein S,Gumerlock MK,Neuwelt EA

    更新日期:1987-09-01 00:00:00

  • Transluminal angioplasty for treatment of intracranial arterial vasospasm.

    abstract::Percutaneous transluminal angioplasty for treatment of intracerebral arterial vasospasm is now being performed in selected cases. Thirty-six vascular territories in 13 patients, ranging in age from 15 to 73 years, have been treated with a new silicone microballoon device. This balloon has allowed mechanical dilatation...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1989.71.5.0648

    authors: Higashida RT,Halbach VV,Cahan LD,Brant-Zawadzki M,Barnwell S,Dowd C,Hieshima GB

    更新日期:1989-11-01 00:00:00

  • Myelopathy due to epidural varicose veins of the cervicothoracic junction. Case report.

    abstract::A 30-year-old man presented with a subacute course of myelopathic signs and symptoms. Magnetic resonance imaging demonstrated an epidural mass lesion of the spinal canal at the cervicothoracic junction causing compression of the spinal cord. Laminectomy with resection of this lesion revealed a large varix with acute a...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1988.69.6.0940

    authors: Dickman CA,Zabramski JM,Sonntag VK,Coons S

    更新日期:1988-12-01 00:00:00

  • Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology.

    abstract::Currently, diagnosis and management of disorders involving nerves are generally undertaken without images of the nerves themselves. The authors evaluated whether direct nerve images obtained using the new technique of magnetic resonance (MR) neurography could be used to make clinically important diagnostic distinction...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1996.85.2.0299

    authors: Filler AG,Kliot M,Howe FA,Hayes CE,Saunders DE,Goodkin R,Bell BA,Winn HR,Griffiths JR,Tsuruda JS

    更新日期:1996-08-01 00:00:00

  • Selection and combination of various endovascular techniques in the treatment of giant aneurysms.

    abstract::Between April, 1989, and January, 1991, a total of 19 cases of giant aneurysm were treated by the endovascular approach. The patients included seven males and 12 females aged 15 to 72 years. Detachable balloons, occlusion coils, and ethylene vinyl alcohol copolymer liquid were used as embolic materials. In seven cases...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1992.77.1.0037

    authors: Taki W,Nishi S,Yamashita K,Sadatoh A,Nakahara I,Kikuchi H,Iwata H

    更新日期:1992-07-01 00:00:00

  • Reconstruction of irreparable brachial plexus injuries with reinnervated free-muscle transfer. Case report.

    abstract::The complete avulsion of the brachial plexus is a severe injury usually caused by high-energy trauma. Even with the advent of modern microsurgical techniques, many patients have been rendered severely handicapped following this injury. The authors present a new reconstructive procedure that uses a microsurgical reinne...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1996.85.1.0174

    authors: Doi K,Sakai K,Fuchigami Y,Kawai S

    更新日期:1996-07-01 00:00:00

  • Use of intercostal nerves for neurotization of the musculocutaneous nerve in infants with birth-related brachial plexus palsy.

    abstract:OBJECT:The use of intercostal nerves (ICNs) for the neurotization of the musculocutaneous nerve (MCN) in adult patients with traumatic brachial plexus palsy has been well described. However, its use for brachial plexus palsy in infants has rarely been reported. The authors surgically created 31 ICN-MCN communications f...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章

    doi:10.3171/jns.2001.94.3.0386

    authors: Kawabata H,Shibata T,Matsui Y,Yasui N

    更新日期:2001-03-01 00:00:00

  • Dural arteriovenous fistula as a late complication of upper cervical spine fracture. Case report.

    abstract::The authors report an unusual case of a dural arteriovenous fistula (DAVF) in the cervical spine after a C1-2 fracture. The patient presented with a delayed epidural hematoma and quadriparesis. The DAVF was successfully treated by coil embolization and the patient made a full recovery. The possibility of a DAVF as a l...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/spi.2004.100.4.0382

    authors: Vankan Y,Demaerel P,Heye S,Van Calenbergh F,van Loon J,Maleux G,Wilms G

    更新日期:2004-04-01 00:00:00

  • Treatment of blunt injury to the carotid artery by using endovascular stents: an early experience.

    abstract::Identification of blunt carotid injury prior to the development of ischemic symptoms requires aggressive screening of patients at risk. The treatment of these lesions has centered around long-term anticoagulation therapy. However, studies have revealed that many of these lesions persist despite medical treatment, as d...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1997.87.6.0825

    authors: Duke BJ,Ryu RK,Coldwell DM,Brega KE

    更新日期:1997-12-01 00:00:00

  • Results of volume-staged fractionated Gamma Knife radiosurgery for large complex arteriovenous malformations: obliteration rates and clinical outcomes of an evolving treatment paradigm.

    abstract::OBJECTIVE There are few reported series regarding volume-staged Gamma Knife radiosurgery (GKRS) for the treatment of large, complex, cerebral arteriovenous malformations (AVMs). The object of this study was to report the results of using volume-staged Gamma Knife radiosurgery for patients affected by large and complex...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2016.7.GKS161549

    authors: Franzin A,Panni P,Spatola G,Del Vecchio A,Gallotti AL,Gigliotti CR,Cavalli A,Donofrio CA,Mortini P

    更新日期:2016-12-01 00:00:00

  • CSF rhinorrhea from a transclival meningocele demonstrated with metrizamide CT cisternography. Case report.

    abstract::A 63-year-old woman with a 10-year history of intermittent cerebrospinal fluid (CSF) rhinorrhea was found to have a transclival meningocele. After pluridirectional tomography demonstrated a bone defect in the clivus, the diagnosis was established by means of computerized tomography (CT) by comparing the absorption coe...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1980.53.4.0553

    authors: Lockwood AH,Quencer RM,Page LK

    更新日期:1980-10-01 00:00:00

  • Nerve reconstruction in lumbosacral plexopathy. Case report and review of the literature.

    abstract::Neurological injury to the lumbosacral plexus associated with pelvic and sacral fractures has traditionally been treated conservatively, despite significant and often debilitating functional deficits of the lower extremities. The authors report a case of reconstruction of the lumbosacral plexus, including nerve grafti...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/ped.2005.102.1.0086

    authors: Tung TH,Martin DZ,Novak CB,Lauryssen C,Mackinnon SE

    更新日期:2005-01-01 00:00:00

  • Invading meningiomas of the sphenoid ridge.

    abstract::The authors report a series of 34 meningiomas of the sphenoid ridge. Eight tumors were totally removed uneventfully: two from the middle sphenoid ridge and six from the pterion or Sylvian point. Five tumors were not operated on because of their extensions or the patient's age. Twenty-one tumors raised serious surgical...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1980.53.5.0587

    authors: Bonnal J,Thibaut A,Brotchi J,Born J

    更新日期:1980-11-01 00:00:00

  • Vascular consequences of operculoinsular corticectomy for refractory epilepsy.

    abstract:OBJECT:Surgery in the insular region is considered challenging because of its vascular relationships, the proximity of functional structures, and its deep location in the sylvian fissure. The authors report the incidence and consequences of ischemic lesions after operculoinsular corticectomy for refractory epilepsy. M...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/2014.10.JNS141246

    authors: Finet P,Nguyen DK,Bouthillier A

    更新日期:2015-06-01 00:00:00

  • Endolymphatic sac tumor demonstrated by intralabyrinthine hemorrhage. Case report.

    abstract::Endolymphatic sac tumors (ELSTs) are locally invasive neoplasms that arise in the posterior petrous bone and are associated with von Hippel-Lindau (VHL) disease. These tumors cause symptoms even when microscopic in size (below the threshold for detectability on imaging studies) and can lead to symptoms such as hearing...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/JNS-07/08/0421

    authors: Jagannathan J,Butman JA,Lonser RR,Vortmeyer AO,Zalewski CK,Brewer C,Oldfield EH,Kim HJ

    更新日期:2007-08-01 00:00:00

  • Overall management outcome of ruptured posterior fossa aneurysms.

    abstract::A study of the overall management of ruptured posterior fossa aneurysms was conducted over a 1-year period (1993) in five neurosurgical centers in Sweden, serving a population of 6.93 million people. Forty-nine cases were identified and treated. One-third of the patients were in the seventh or eighth decade of life. G...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章

    doi:10.3171/jns.1996.85.1.0033

    authors: Hillman J,Säveland H,Jakobsson KE,Edner G,Zygmunt S,Fridriksson S,Brandt L

    更新日期:1996-07-01 00:00:00