Abstract:
:The modulatory influence of pretectal neurons on retino-geniculate transmission in the cat was studied by cross-correlation analysis of single-unit activity simultaneously recorded from the dorsal lateral geniculate nucleus (dLGN) and the pretectum (PT) and with reversible inactivation of the PT by GABA microiontophoresis during simultaneous visual stimulation of PT and dLGN neurons. Visually induced population activity in PT nuclei was achieved by a moving (or counterphasing) grating which was presented in the background of the light spot used to stimulate the dLGN neuron. As a control, the light spot was presented on a stationary grating to avoid stimulation of PT neurons but to yield the same illumination of the background. Extracellularly recorded dLGN relay cells of the X- and Y-type were found to be differentially affected by the PT-dLGN projection. During visual stimulation of PT cells, X cells were strongly inhibited and this effect was significantly reduced during PT inactivation. By contrast, the visual responses of most Y cells were affected neither by PT stimulation nor by PT inactivation. In addition, the temporal structure of spike patterns during the light response was examined with autocorrelograms and spike-interval distributions. X-on cells often exhibited a multimodal interval distribution and oscillatory type of activity. During stimulation of the PT interval distributions changed in a characteristic manner and oscillations disappeared. Both effects could be almost totally cancelled by PT inactivation. By contrast, the temporal structure of Y-cell responses was not affected. Our results demonstrate for the first time a pretectal modulation of retino-geniculate transmission in cat dLGN which is clearly different for X and Y cells. This influence seems to be mediated via (inhibitory) interneurons, since we found no indication for a direct coupling between PT and dLGN units. This projection might contribute to the well-known phenomenon of saccadic suppression.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Funke K,Eysel UTdoi
10.1017/s0952523800007288subject
Has Abstractpub_date
1995-01-01 00:00:00pages
21-33issue
1eissn
0952-5238issn
1469-8714pii
S0952523800007288journal_volume
12pub_type
杂志文章abstract::Adult Japanese quail have an endogenous circadian clock located in their eyes that has been shown to regulate melatonin biosynthesis. We investigated if a circadian oscillator is present in cultures of dispersed embryonic quail retina. Melatonin release in retinal cell culture is modulated by the light cycle, indicati...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523899165040
更新日期:1999-09-01 00:00:00
abstract::The phosphoinositide (PI) intracellular signaling pathway, which triggers Ca2+ release from intracellular stores, appears to be a central feature of phototransduction in most invertebrate species studied. Procedures designed to inhibit PI-pathway reactions cause suppression of excitation to dim lights. However, in Lim...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523898151076
更新日期:1998-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005964
更新日期:1989-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800010531
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journal_title:Visual neuroscience
pub_type: 杂志文章
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更新日期:1998-09-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800006751
更新日期:1995-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008774
更新日期:1997-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008105
更新日期:1996-05-01 00:00:00
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journal_title:Visual neuroscience
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doi:10.1017/S0952523816000134
更新日期:2016-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S095252381300059X
更新日期:2014-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523807070137
更新日期:2007-05-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523814000066
更新日期:2014-05-01 00:00:00
abstract::The Tennessee Mouse Genome Consortium (TMGC) is in its fifth year of a ethylnitrosourea (ENU)-based mutagenesis screen to detect recessive mutations that affect the eye and brain. Each pedigree is tested by various phenotyping domains including the eye, neurohistology, behavior, aging, ethanol, drug, social behavior, ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523805225087
更新日期:2005-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0952523800171093
更新日期:2000-01-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523801184142
更新日期:2001-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800002558
更新日期:1991-06-01 00:00:00
abstract::The distribution of GABA-like immunoreactivity in the cat retina was studied through the use of preembedding immunocytochemistry for light microscopy and by postembedding immunogold techniques for electron microscopy. Staining was observed in both inner and outer plexiform layers. Approximately 30% of the somata in th...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800012323
更新日期:1989-01-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:1991-07-01 00:00:00
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更新日期:1999-07-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
abstract::GABA is a major inhibitory neurotransmitter in the mammalian retina and it acts at many different sites via a variety of postsynaptic receptors. These include GABAA receptors and bicuculline-resistant GABAC receptors. The release of acetylcholine (ACh) is inhibited by GABA and strongly potentiated by GABA antagonists....
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800011652
更新日期:1997-09-01 00:00:00
abstract::Ganglion cells of the cat retina that are neither alpha nor beta cells are often lumped for convenience into a single anatomical group--the gamma cells (Boycott & Wässle, 1974; Stone, 1983; Wässle & Boycott, 1991). Defined in this way, gamma cells are the morphological counterpart to the physiological W-cell class, wh...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380000897x
更新日期:1995-07-01 00:00:00
abstract::Immunocytochemistry and retrograde labeling were used to define the thalamic projections of calbindin- and parvalbumin-containing cells in superficial layers of the rat's superior colliculus (SC). Quantitative analysis revealed that 90.8 +/- 2.2% (mean +/- standard deviation) of the calbindin-immunoreactive neurons in...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380001141x
更新日期:1997-03-01 00:00:00
abstract::The abundance and spatial distribution of retinal cone photoreceptors change during thyroid hormone (TH)-induced and natural development of rainbow trout (Oncorhynchus mykiss). These changes are thought to allow the fish to adapt to different photic environments throughout its life history. To date, the ontogeny of ra...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806232139
更新日期:2006-03-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:1990-12-01 00:00:00
abstract::The technique of current source-density analysis was applied to several components of the light-evoked field potentials (electroretinogram) from the retina of the superfused eyecup of rabbit. The depth distributions of the major current sources and sinks were: b-wave--sink at outer plexiform layer, source at inner ple...
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更新日期:1999-03-01 00:00:00
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journal_title:Visual neuroscience
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doi:10.1017/S0952523808080930
更新日期:2009-01-01 00:00:00