Abstract:
:Rabbits received ibotenic acid lesions of the mediodorsal nucleus of the thalamus (MD) or sham lesions. These animals were compared on four sessions of instrumental avoidance conditioning, during which an eyeblink (EB) response during the presentation of a tone-conditioned stimulus prevented the occurrence of a paraorbital electric shock unconditioned stimulus. Lesions of MD retarded acquisition of the EB avoidance response, but did not affect asymptotic performance. Concomitant heart rate (HR) changes were little affected by MD lesions, although there was some evidence that such changes were slightly larger in MD-lesioned animals. These results suggest that MD participates in some general aspect of the learning process, perhaps by affecting other behavioral processes such as 'attention' or 'arousal'.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Buchanan SLdoi
10.1016/0166-4328(94)90103-1subject
Has Abstractpub_date
1994-12-15 00:00:00pages
173-9issue
2eissn
0166-4328issn
1872-7549pii
0166-4328(94)90103-1journal_volume
65pub_type
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