The effect of B1 field inhomogeneity and the nonselective inversion profile on the kinetics of FAIR-based perfusion MRI.

Abstract:

:Perfusion imaging with pulsed arterial spin labeling techniques, like flow-sensitive alternating inversion recovery (FAIR), may suffer from inflow of fresh, i.e., unlabeled, spins. Inflow of fresh spins is caused by the arrival of unlabeled spins in the image slice and can lead to underestimation of the perfusion if not taken into account. In this study it was shown that a decrease in B(1) field strength toward the edge of the transmit coil and the consequent reduction in the inversion efficiency leads to a narrowing of the arterial delivery function and a reduction in FAIR signal. Increasing the B(1) amplitude of the adiabatic inversion pulse from 2.3 to 5.7 times its minimum amplitude requirement resulted in an observed increase of 40 to 80% in the rat brain FAIR signal at inflow times longer than 0.65 s. For coils with limited dimensions and significant B(1) inhomogeneity over the perfusion labeling slab, the application of an excessively large B(1) amplitude in combination with adiabatic inversion is recommended to optimize the FAIR perfusion contrast.

journal_name

Magn Reson Med

authors

Schepers J,van Osch MJ,Bartels LW,Heukels SN,Viergever MA,Nicolay K

doi

10.1002/mrm.20480

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

1355-62

issue

6

eissn

0740-3194

issn

1522-2594

journal_volume

53

pub_type

杂志文章
  • Spatial-frequency-tuned markers and adaptive correction for rotational motion.

    abstract::A common type of motion present in clinical magnetic resonance imaging examinations is rotational motion, such as that due to voluntary motion during head examinations. The correction scheme presented in this work offers a method for eliminating the effects of rotations within the imaging plane. Integral to the implem...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910330511

    authors: Korin HW,Felmlee JP,Riederer SJ,Ehman RL

    更新日期:1995-05-01 00:00:00

  • Stability constants and 1H relaxation effects of ternary complexes formed between Gd-DTPA, Gd-DTPA-BMA, Gd-DOTA, and Gd-EDTA and citrate, phosphate, and carbonate ions.

    abstract::Formation of ternary complexes between Gd-DTPA, Gd-DTPA-BMA, and Gd-DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz, rates is negligibl...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910380120

    authors: Burai L,Hietapelto V,Király R,Tóth E,Brücher E

    更新日期:1997-07-01 00:00:00

  • The importance of correcting for signal drift in diffusion MRI.

    abstract:PURPOSE:To investigate previously unreported effects of signal drift as a result of temporal scanner instability on diffusion MRI data analysis and to propose a method to correct this signal drift. METHODS:We investigated the signal magnitude of non-diffusion-weighted EPI volumes in a series of diffusion-weighted imag...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26124

    authors: Vos SB,Tax CM,Luijten PR,Ourselin S,Leemans A,Froeling M

    更新日期:2017-01-01 00:00:00

  • Fat-water separation based on Transition REgion Extraction (TREE).

    abstract:PURPOSE:To develop a method based on fat-water transition region extraction (TREE) for robust fat-water separation and quantification in challenging scenarios, including low signal-to-noise ratio (SNR), fast changing B0 field, and disjointed anatomies. THEORY AND METHODS:In TREE method, the phasor solutions of each pi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27710

    authors: Peng H,Zou C,Cheng C,Tie C,Qiao Y,Wan Q,Lv J,He Q,Liang D,Liu X,Liu W,Zheng H

    更新日期:2019-07-01 00:00:00

  • Evaluation of fluorine-19 magnetic resonance imaging of the lungs using octafluorocyclobutane in a rat model.

    abstract:PURPOSE:To test octafluorocyclobutane (OFCB) as an inhalation contrast agent for fluorine-19 MRI of the lung, and to compare the image quality of OFCB scans with perfluoropropane (PFP) scans THEORY AND METHODS: After normalizing for the number of signal averages, a theoretical comparison between the OFCB signal-to-nois...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.28473

    authors: Shepelytskyi Y,Li T,Grynko V,Newman C,Hane FT,Albert MS

    更新日期:2021-02-01 00:00:00

  • Perfusion-weighted imaging of interictal hypoperfusion in temporal lobe epilepsy using FAIR-HASTE: comparison with H(2)(15)O PET measurements.

    abstract::To detect perfusion abnormalities in areas of high magnetic susceptibility in the brain, an arterial spin-labeling MRI technique utilizing flow-sensitive alternating inversion recovery (FAIR) and half-Fourier single shot turbo spin-echo (HASTE) for spin preparation and image acquisition, respectively, was developed. I...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/1522-2594(200103)45:3<431::aid-mrm1056>3.0

    authors: Liu HL,Kochunov P,Hou J,Pu Y,Mahankali S,Feng CM,Yee SH,Wan YL,Fox PT,Gao JH

    更新日期:2001-03-01 00:00:00

  • Evaluation of MRI resolution affecting trabecular bone parameters: determination of acceptable resolution.

    abstract::The objective of this study is to evaluate the effect of MR image resolution on trabecular bone parameters and to determine the acceptable resolution that can be accurately analyzed to assess structural parameters. Ten distal femoral condyle specimens of 1 × 1 × 1 cm(3) were scanned with a 4.7-T Bruker BioSpec MRI sca...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22984

    authors: Kim N,Lee JG,Song Y,Kim HJ,S Yeom J,Cho G

    更新日期:2012-01-01 00:00:00

  • Measuring extracellular volume fraction by MRI: First verification of values given by clinical sequences.

    abstract:PURPOSE:To verify MR measurements of myocardial extracellular volume fraction (ECV) based on clinically applicable T1-mapping sequences against ECV measurements by radioisotope tracer in pigs and to relate the results to those obtained in volunteers. METHODS:Between May 2016 and March 2017, 8 volunteers (25 ± 4 years,...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.27938

    authors: Nordlund D,Xanthis C,Bidhult S,Jablonowski R,Kanski M,Kopic S,Carlsson M,Engblom H,Aletras AH,Arheden H

    更新日期:2020-02-01 00:00:00

  • Generalized MR interferography.

    abstract::Generalized MR interferography allows the measurement of parameters which affect the phase of the MR signal. Interference is generated by the simultaneous generation of two echoes in one excitation cycle. Local variations of the signal phase are transformed into displacement of the stripe pattern generated by interfer...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910160305

    authors: Hennig J

    更新日期:1990-12-01 00:00:00

  • Selective excitation of two-dimensional arbitrarily shaped voxels with parallel excitation in spectroscopy.

    abstract::Parallel excitation is being studied intensively for applications in MR imaging and in particular for selecting arbitrary shapes as regions of interest. In this work, parallel excitation was applied to arbitrarily shaped voxel selection in spectroscopy and investigated for different excitation k-space trajectories (ra...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23018

    authors: Snyder J,Haas M,Hennig J,Zaitsev M

    更新日期:2012-02-01 00:00:00

  • Mean magnetic susceptibility regularized susceptibility tensor imaging (MMSR-STI) for estimating orientations of white matter fibers in human brain.

    abstract:PURPOSE:An increasing number of studies show that magnetic susceptibility in white matter fibers is anisotropic and may be described by a tensor. However, the limited head rotation possible for in vivo human studies leads to an ill-conditioned inverse problem in susceptibility tensor imaging (STI). Here we suggest the ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25322

    authors: Li X,van Zijl PC

    更新日期:2014-09-01 00:00:00

  • Dynamic changes in water ADC, energy metabolism, extracellular space volume, and tortuosity in neonatal rat brain during global ischemia.

    abstract::To obtain a better understanding of the mechanisms underlying early changes in the brain water apparent diffusion coefficient (ADC) observed in cerebral ischemia, dynamic changes in the ADC of water and in the energy status were measured at postnatal day 8 or 9 in neonatal rat brains after cardiac arrest using 1H MRS/...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910360110

    authors: van der Toorn A,Syková E,Dijkhuizen RM,Vorísek I,Vargová L,Skobisová E,van Lookeren Campagne M,Reese T,Nicolay K

    更新日期:1996-07-01 00:00:00

  • Magnetic field and tissue dependencies of human brain longitudinal 1H2O relaxation in vivo.

    abstract::Brain water proton (1H2O) longitudinal relaxation time constants (T1) were obtained from three healthy individuals at magnetic field strengths (B0) of 0.2 Tesla (T), 1.0T, 1.5T, 4.0T, and 7.0T. A 5-mm midventricular axial slice was sampled using a modified Look-Locker technique with 1.5 mm in-plane resolution, and 32 ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21122

    authors: Rooney WD,Johnson G,Li X,Cohen ER,Kim SG,Ugurbil K,Springer CS Jr

    更新日期:2007-02-01 00:00:00

  • Characterization of estrogen-receptor-targeted contrast agents in solution, breast cancer cells, and tumors in vivo.

    abstract::The estrogen receptor (ER) is a major prognostic biomarker of breast cancer, currently determined in surgical specimens by immunohistochemistry. Two new ER-targeted probes, pyridine-tetra-acetate-Gd chelate (PTA-Gd) conjugated either to 17β-estradiol (EPTA-Gd) or to tamoxifen (TPTA-Gd), were explored as contrast agent...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.24442

    authors: Pais A,Biton IE,Margalit R,Degani H

    更新日期:2013-07-01 00:00:00

  • Self-calibrating parallel imaging with automatic coil sensitivity extraction.

    abstract::Calibration of the spatial sensitivity functions of coil arrays is a crucial element in parallel magnetic resonance imaging (PMRI). The most common approach has been to measure coil sensitivities directly using one or more low-resolution images acquired before or after accelerated data acquisition. However, since it i...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10087

    authors: McKenzie CA,Yeh EN,Ohliger MA,Price MD,Sodickson DK

    更新日期:2002-03-01 00:00:00

  • Biodegradable, polymer encapsulated, metal oxide particles for MRI-based cell tracking.

    abstract::Metallic particles have shaped the use of magnetic resonance imaging (MRI) for molecular and cellular imaging. Although these particles have generally been developed for extracellular residence, either as blood pool contrast agents or targeted contrast agents, the coopted use of these particles for intracellular label...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章,评审

    doi:10.1002/mrm.25263

    authors: Shapiro EM

    更新日期:2015-01-01 00:00:00

  • Dysprosium-bearing red cells as potential transverse relaxation agents for MRI.

    abstract::The cytosol of intact human red blood cells was loaded with 28.1 +/- 3.4 mM of dysprosium DTPA-BMA using a hypoosmotic technique. When loaded cells were diluted with saline and control cells to give an average dysprosium concentration of 3.3 +/- 0.5 mM, the transverse relaxation rate constants R(*)(2) and R(2) increas...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1122

    authors: Johnson KM,Tao JZ,Kennan RP,Gore JC

    更新日期:2001-05-01 00:00:00

  • Partial Fourier techniques in single-shot cross-term spatiotemporal encoded MRI.

    abstract:PURPOSE:Cross-term spatiotemporal encoding (xSPEN) is a single-shot approach with exceptional immunity to field heterogeneities, the images of which faithfully deliver 2D spatial distributions without requiring a priori information or using postacquisition corrections. xSPEN, however, suffers from signal-to-noise ratio...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.26824

    authors: Zhang Z,Frydman L

    更新日期:2018-03-01 00:00:00

  • Intravoxel incoherent motion imaging using steady-state free precession.

    abstract::IVIM MR imaging is a method which generates images of diffusion and perfusion in vivo. Until now, intravoxel incoherent motion (IVIM) images have been obtained using spin-echo sequences with extragradient pulses, resulting in long acquisition times (typically 2 x 8 min 32 s). A new method is proposed here, using stead...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910070312

    authors: Le Bihan D

    更新日期:1988-07-01 00:00:00

  • New "multicolor" polypeptide diamagnetic chemical exchange saturation transfer (DIACEST) contrast agents for MRI.

    abstract::An array of 33 prototype polypeptides was examined as putative contrast agents that can be distinguished from each other based on the chemical exchange saturation transfer (CEST) mechanism. These peptides were chosen based on predictions of the chemical exchange rates of exchangeable amide, amine, and hydroxyl protons...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21683

    authors: McMahon MT,Gilad AA,DeLiso MA,Berman SM,Bulte JW,van Zijl PC

    更新日期:2008-10-01 00:00:00

  • Toward direct mapping of neuronal activity: MRI detection of ultraweak, transient magnetic field changes.

    abstract::A novel method based on selective detection of rapidly changing DeltaB(0) magnetic fields and suppression of slowly changing DeltaB(0) fields is presented. The ultimate goal of this work is to present a method that may allow detection of transient and subtle changes in B(0) in cortical tissue associated with electrica...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.10159

    authors: Bodurka J,Bandettini PA

    更新日期:2002-06-01 00:00:00

  • Single-shot two-echo technique for simultaneous measurement of GABA and creatine in the human brain in vivo.

    abstract::A single-shot, two-echo method for the simultaneous detection of multiple-quantum (MQ)-filtered gamma-aminobutyric acid (GABA) and creatine (Cr) was developed and demonstrated in the human brain in vivo at 3 Tesla. The simultaneously measured Cr singlet served as a navigator for the spectral phase of GABA and any freq...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.20082

    authors: Choi IY,Lee SP,Merkle H,Shen J

    更新日期:2004-06-01 00:00:00

  • Prospective real-time head motion correction using inductively coupled wireless NMR probes.

    abstract:PURPOSE:Head motion continues to be a major source of artifacts and data quality degradation in MRI. The goal of this work was to develop and demonstrate a novel technique for prospective, 6 degrees of freedom (6DOF) rigid body motion estimation and real-time motion correction using inductively coupled wireless nuclear...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25001

    authors: Sengupta S,Tadanki S,Gore JC,Welch EB

    更新日期:2014-10-01 00:00:00

  • On the origin of paramagnetic inhomogeneity effects in blood.

    abstract::Hydrogen, sodium, and fluorine (added F-) NMR spectra of venous and oxygenated blood were measured. The fluorine resonance was seen as a single peak in both samples, and all three resonances exhibited the same deoxy-oxy shift. Because F- exchanges slowly across the red cell membrane, and because sodium is 95% extracel...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910120210

    authors: Brooks RA,Brunetti A,Alger JR,Di Chiro G

    更新日期:1989-11-01 00:00:00

  • Phase contrast MRI with flow compensation view sharing.

    abstract:PURPOSE:To develop and evaluate a technique for accelerating phase contrast MRI (PC-MRI) acquisitions without significant compromise in flow quantification accuracy. METHODS:PC-MRI is commonly acquired using interleaved flow-compensated (FC) and flow-encoded (FE) echoes. We hypothesized that FC data, which represent b...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.25133

    authors: Wang D,Shao J,Rapacchi S,Middione MJ,Ennis DB,Hu P

    更新日期:2015-02-01 00:00:00

  • Aldehyde fixative solutions alter the water relaxation and diffusion properties of nervous tissue.

    abstract::Chemically-fixed nervous tissues are well-suited for high-resolution, time-intensive MRI acquisitions without motion artifacts, such as those required for brain atlas projects, but the aldehyde fixatives used may significantly alter tissue MRI properties. To test this hypothesis, this study characterized the impact of...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.21977

    authors: Shepherd TM,Thelwall PE,Stanisz GJ,Blackband SJ

    更新日期:2009-07-01 00:00:00

  • Specific absorption rate benefits of including measured electric field interactions in parallel excitation pulse design.

    abstract::Specific absorption rate management and excitation fidelity are key aspects of radiofrequency pulse design for parallel transmission at ultra-high magnetic field strength. The design of radiofrequency pulses for multiple channels is often based on the solution of regularized least-squares optimization problems for whi...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.23004

    authors: Deniz CM,Alon L,Brown R,Sodickson DK,Zhu Y

    更新日期:2012-01-01 00:00:00

  • Observing curved flow using RUFIS.

    abstract::The rotating ultra-fast imaging sequence (RUFIS) is used to image spins flowing through the curved portion of a 180 degrees U-tube with a circular cross section and a ratio of inner diameter to curvature diameter of 0.41. A velocity-encoding preparation sequence is used with RUFIS to measure quantitatively the axial v...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/(sici)1522-2594(199906)41:6<1258::aid-mrm2

    authors: Gach HM,Lowe IJ

    更新日期:1999-06-01 00:00:00

  • Effects of polar sampling in k-space.

    abstract::Magnetic resonance imaging allows numerous k-space sampling schemes such as cartesian, polar, spherical, and other non-rectilinear trajectories. Non-rectilinear MR acquisitions permit fast scan times and can suppress motion artifacts. Still, these sampling schemes may adversely affect the image characteristics due to ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.1910360617

    authors: Lauzon ML,Rutt BK

    更新日期:1996-12-01 00:00:00

  • Reduction of B1 sensitivity in selective single-slab 3D turbo spin echo imaging with very long echo trains.

    abstract::Single-slab 3D turbo/fast spin echo (SE) imaging with very long echo trains was recently introduced with slab selection using a highly selective excitation pulse and short, nonselective refocusing pulses with variable flip angles for high imaging efficiency. This technique, however, is vulnerable to image degradation ...

    journal_title:Magnetic resonance in medicine

    pub_type: 杂志文章

    doi:10.1002/mrm.22070

    authors: Park J,Mugler JP 3rd,Hughes T

    更新日期:2009-10-01 00:00:00