Fourier rebinning of time-of-flight PET data.

abstract：:We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database...

journal_title：Physics in medicine and biology

authors： Chen W,Unkelbach J,Trofimov A,Madden T,Kooy H,Bortfeld T,Craft D

更新日期：2012-02-07 00:00:00

abstract：:The relative stopping power (RSP) uncertainty is the largest contributor to the range uncertainty in proton therapy. The purpose of this work was to develop a systematic method that yields accurate and patient-specific RSPs by combining (1) pre-treatment x-ray CT and (2) daily proton radiography of the patient. The me...

journal_title：Physics in medicine and biology

authors： Collins-Fekete CA,Brousmiche S,Hansen DC,Beaulieu L,Seco J

更新日期：2017-08-03 00:00:00

abstract：:Values of the relative permittivity and conductivity of the rabbit retina and lens have been measured between 10 MHz and 10 GHz over the temperature range 20 to -20 degrees C. As the temperature was lowered from 20 degrees C the dielectric parameters changed smoothly until -9 degrees C where freezing occurred. At this...

journal_title：Physics in medicine and biology

authors： Gabriel C,Grant EH

更新日期：1985-09-01 00:00:00

abstract：:A cost-effective method employing polysulphone, nalidixic acid, 8-methoxypsoralen and phenothiazine as UV dosimeters is presented for evaluating the UV spectrum. The exposure measured by each dosimeter is a function of the source spectrum and the spectral response of the material. Each material has a different spectra...

journal_title：Physics in medicine and biology

authors： Parisi AV,Wong JC,Moore GI

更新日期：1997-01-01 00:00:00

abstract：:Accurate scatter correction is especially important for high-resolution 3D positron emission tomographies (PETs) such as high-resolution research tomograph (HRRT) due to large scatter fraction in the data. To address this problem, a fully 3D iterative scatter-corrected ordered subset expectation maximization (OSEM) in...

journal_title：Physics in medicine and biology

authors： Kim KS,Ye JC

更新日期：2011-08-07 00:00:00

abstract：:Four-dimensional volumetric modulated arc therapy (4D VMAT) is a treatment strategy for lung cancers that aims to exploit relative target and tissue motion to improve organ at risk (OAR) sparing. The algorithm incorporates the entire patient respiratory cycle using 4D CT data into the optimization process. Resulting t...

journal_title：Physics in medicine and biology

authors： Chin E,Loewen SK,Nichol A,Otto K

更新日期：2013-02-21 00:00:00

abstract：:An ultrahigh-resolution full-field optical coherence tomography (OCT) system has been developed for cellular-level imaging of biological media. The system is based on a Linnik interference microscope illuminated with a tungsten halogen lamp, associated with a high-resolution CCD camera. En face tomographic images are ...

journal_title：Physics in medicine and biology

authors： Dubois A,Moneron G,Grieve K,Boccara AC

更新日期：2004-04-07 00:00:00

abstract：:Grating interferometry is advantageous over conventional x-ray absorption imaging because it enables the detection of samples constituted by low atomic number elements (low-Z materials). Therefore, it has a potential application in biological science and medical diagnostics. The grating interferometry has some critica...

journal_title：Physics in medicine and biology

authors： Du Y,Lei Y,Liu X,Huang J,Zhao Z,Guo J,Li J,Niu H

更新日期：2016-12-07 00:00:00

abstract：:All radiation therapy treatment planning relies on accurate dose calculation. Uncertainties in dosimetric prediction can significantly degrade an otherwise optimal plan. In this work, we introduce a robust optimization method which handles dosimetric errors and warrants for high-quality IMRT plans. Unlike other dose e...

journal_title：Physics in medicine and biology

authors： Nohadani O,Seco J,Martin BC,Bortfeld T

更新日期：2009-06-07 00:00:00

abstract：:Silicon diodes have good spatial resolution, which makes them advantageous over ionization chambers for dosimetry in fields with high dose gradients. However, silicon diodes overrespond to low-energy photons, that are more abundant in scatter which increase with large fields and larger depths. We present a cavity-theo...

journal_title：Physics in medicine and biology

authors： Eklund K,Ahnesjö A

更新日期：2009-10-21 00:00:00

abstract：:In the field of regenerative medicine, there has been a growing interest in studying the combination of bone scaffolds and cells that can maximize newly formed bone. In-line phase-contrast x-ray tomography was used to image porous bone scaffolds (Skelite(©)), seeded with bone forming cells. This technique allows the q...

journal_title：Physics in medicine and biology

authors： Weber L,Langer M,Tavella S,Ruggiu A,Peyrin F

更新日期：2016-05-07 00:00:00

abstract：:We propose a retrospective respiratory gating algorithm to generate dynamic CT studies. To this end, we compared three different methods of extracting the respiratory signal from the projections of small-animal cone-beam computed tomography (CBCT) scanners. Given a set of frames acquired from a certain axial angle, su...

journal_title：Physics in medicine and biology

authors： Chavarrías C,Vaquero JJ,Sisniega A,Rodríguez-Ruano A,Soto-Montenegro ML,García-Barreno P,Desco M

更新日期：2008-09-07 00:00:00

abstract：:In this note a technique is described for direct aperture optimization of components deliverable by a variable aperture collimator (VAC) for intensity-modulated radiation therapy. The first key result found was that, provided a large number of VAC components were selected for optimization, the resulting fluence profil...

journal_title：Physics in medicine and biology

authors： Webb S

更新日期：2004-03-07 00:00:00

abstract：:Inverse treatment planning in intensity modulated particle therapy (IMPT) with scanned carbon-ion beams is currently based on the optimization of RBE-weighted dose to satisfy requirements of target coverage and limited toxicity to organs-at-risk (OARs) and healthy tissues. There are many feasible IMPT plans that meet ...

journal_title：Physics in medicine and biology

authors： Burigo LN,Ramos-Méndez J,Bangert M,Schulte RW,Faddegon B

更新日期：2019-01-04 00:00:00

abstract：:A method is presented for extraction of intra and inter fraction motion of seeds/markers within the patient from cone beam CT (CBCT) projection images. The position of the marker is determined on each projection image and fitted to a function describing the projection of a fixed point onto the imaging panel at differe...

journal_title：Physics in medicine and biology

authors： Marchant TE,Amer AM,Moore CJ

更新日期：2008-02-21 00:00:00

abstract：:In brachytherapy, plans are routinely calculated using the AAPM TG43 formalism which considers the patient as a simple water object. An accurate modeling of the physical processes considering patient heterogeneity using Monte Carlo simulation (MCS) methods is currently too time-consuming and computationally demanding ...

journal_title：Physics in medicine and biology

authors： Lemaréchal Y,Bert J,Falconnet C,Després P,Valeri A,Schick U,Pradier O,Garcia MP,Boussion N,Visvikis D

更新日期：2015-07-07 00:00:00

abstract：:An extensive study on specific absorption rate (SAR) covering 720 simulations and 15 voxel models (18-105 kg) has been performed by applying the parallel finite-difference time-domain method. High-resolution whole-body models have been irradiated with plane waves from 300 MHz to 5 GHz by applying various incoming dire...

journal_title：Physics in medicine and biology

authors： Uusitupa T,Laakso I,Ilvonen S,Nikoskinen K

更新日期：2010-02-21 00:00:00

abstract：:Dual spectral computed tomography (DSCT) has a superior material distinguishability than the conventional single spectral computed tomography (SSCT). However, the decomposition process is an illposed problem, which is sensitive to noise. Thus, the decomposed image quality is degraded, and the corresponding signal-to-n...

journal_title：Physics in medicine and biology

authors： Wang Q,Zhu Y,Yu H

更新日期：2017-10-19 00:00:00

abstract：:The potential of the variable-aperture collimator (VAC) in intensity-modulated radiation therapy (IMRT) has been evaluated by comparing its performance with that of the multi-leaf collimator (MLC). This comparison used a decomposition algorithm to find the series of collimator segments that would treat a given intensi...

journal_title：Physics in medicine and biology

authors： Anderson JW,Symonds-Tayler R,Hartmann G,Echner G,Lang C,Schlegel W,Webb S

更新日期：2006-04-07 00:00:00

abstract：:Absorbed dose values were determined under the reference conditions in a phantom irradiated by high-energy photon beams with quality varying between 60Co gamma rays and 25 MV X-rays, using four commonly employed types of ionisation chamber. The ionisation chamber readings were converted to absorbed dose values applyin...

journal_title：Physics in medicine and biology

authors： Mijnheer BJ,Wittkämper FW

更新日期：1986-04-01 00:00:00

abstract：:A common dose-saving technique used in modern CT devices is automatic tube current modulation (TCM), which was originally designed to also reduce the dose in paediatric CT patients. In order to be able to deduce detailed organ doses of paediatric models, dose conversion coefficients normalized to CTDI(vol) for an eigh...

journal_title：Physics in medicine and biology

authors： Schlattl H,Zankl M,Becker J,Hoeschen C

更新日期：2012-10-21 00:00:00

abstract：:A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real decrement to the imaginary part of the complex refractive index, the proposed metho...

journal_title：Physics in medicine and biology

authors： Gureyev TE,Paganin DM,Arhatari B,Taba ST,Lewis S,Brennan PC,Quiney HM

更新日期：2020-11-17 00:00:00

abstract：:Ultrasound may provide a quantitative technique for the characterization of cartilage changes typical of early osteoarthrosis. In this study, specific changes in bovine articular cartilage were induced using collagenase and chondroitinase ABC, enzymes that selectively degrade collagen fibril network and digest proteog...

journal_title：Physics in medicine and biology

authors： Töyräs J,Rieppo J,Nieminen MT,Helminen HJ,Jurvelin JS

更新日期：1999-11-01 00:00:00

abstract：:In radiofrequency (RF) ablation or hyperthermia, internal temperature measurements and tissue property imaging are important to control their outputs and assess the treatment effect. Recently, magnetic resonance electrical impedance tomography (MREIT), as a non-invasive imaging method of internal conductivity distribu...

journal_title：Physics in medicine and biology

authors： Oh TI,Kim HJ,Jeong WC,Chauhan M,Kwon OI,Woo EJ

更新日期：2013-04-21 00:00:00

abstract：:Ultrasound current source density imaging (UCSDI) exploits the acoustoelectric (AE) effect, an interaction between ultrasound pressure and electrical resistivity, to map electrical conduction in the heart. The conversion efficiency for UCSDI is determined by the AE interaction constant K, a fundamental property of all...

journal_title：Physics in medicine and biology

authors： Li Q,Olafsson R,Ingram P,Wang Z,Witte R

更新日期：2012-10-07 00:00:00

abstract：:Reliable treatment planning of highly conformal scanned ion beam therapy demands accurate tools for the determination and characterization of the individual pencil-like beams building up the integral dose delivery and related mixed radiation field. At present, clinically practicable inverse treatment planning systems ...

journal_title：Physics in medicine and biology

authors： Parodi K,Mairani A,Brons S,Hasch BG,Sommerer F,Naumann J,Jäkel O,Haberer T,Debus J

更新日期：2012-06-21 00:00:00

abstract：:Several papers have recently addressed the issue of estimating chromophore concentration in optoacoustic imaging (OAI) using multiple wavelengths. The choice of wavelengths obviously affects the accuracy and precision of the estimates. One might assume that the wavelengths that maximize the extinction coefficients of ...

journal_title：Physics in medicine and biology

authors： Modgil D,La Riviére PJ

更新日期：2010-12-07 00:00:00

abstract：PURPOSE:A system for long-length intraoperative imaging is reported based on longitudinal motion of an O-arm gantry featuring a multi-slot collimator. We assess the utility of long-length tomosynthesis and the geometric accuracy of 3D image registration for surgical guidance and evaluation of long spinal constructs. M...

journal_title：Physics in medicine and biology

authors： Zhang X,Uneri A,Wu P,Ketcha MD,Jones C,Huang Y,Lo SL,Helm PA,Siewerdsen JH

更新日期：2021-01-21 00:00:00

abstract：:Compartmental models are widely used for the mathematical modelling of dynamic studies acquired with positron emission tomography (PET). The numerical problem involves the estimation of a sum of decaying real exponentials convolved with an input function. In exponential spectral analysis (SA), the nonlinear estimation...

journal_title：Physics in medicine and biology

authors： Turkheimer FE,Hinz R,Gunn RN,Aston JA,Gunn SR,Cunningham VJ

更新日期：2003-12-07 00:00:00

abstract：:In radiotherapy with photon beams, the use of dynamic wedges, which are obtained by the movement of one of the jaws, offers an increasing flexibility relative to the traditional use of metal wedges. But it is a disadvantage for the measurement of absorbed dose distributions, because the absorbed dose at each measureme...

journal_title：Physics in medicine and biology

authors： Storchi P,Woudstra E,Verlinde P,Johansson KA,Samuelsson A

更新日期：1998-06-01 00:00:00