Abstract:
:The effects of chlorpromazine on either the activity of mouse brain nitric oxide synthase or the induction of lung nitric oxide synthase in mice and rats were studied. Chlorpromazine inhibited the nitric oxide synthase activity in mouse brain cytosol. This effect could be reversed by adding an excess of calmodulin. In addition, chlorpromazine was able to inhibit the induction of lung nitric oxide synthase, in both species, after LPS administration. Furthermore, chlorpromazine also inhibited arginase activity in mouse lung cytosol.
journal_name
Biochem Biophys Res Communjournal_title
Biochemical and biophysical research communicationsauthors
Palacios M,Padron J,Glaria L,Rojas A,Delgado R,Knowles R,Moncada Sdoi
10.1006/bbrc.1993.2246subject
Has Abstractpub_date
1993-10-15 00:00:00pages
280-6issue
1eissn
0006-291Xissn
1090-2104pii
S0006-291X(83)72246-1journal_volume
196pub_type
杂志文章abstract::Most in vivo studies on the conversion to insulin-producing cells with AAV carrying PDX1 gene are performed in rodents. However, there is little information regarding Adeno-associated virus (AAV) carrying PDX1 gene transduced to human liver in vivo because accidental death caused by unpredicted factors cannot be denie...
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journal_title:Biochemical and biophysical research communications
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journal_title:Biochemical and biophysical research communications
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更新日期:2012-05-04 00:00:00
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journal_title:Biochemical and biophysical research communications
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更新日期:2006-09-22 00:00:00
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更新日期:2000-12-09 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.bbrc.2013.07.043
更新日期:2013-08-16 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
doi:10.1006/bbrc.1994.2480
更新日期:1994-10-28 00:00:00
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journal_title:Biochemical and biophysical research communications
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doi:10.1016/j.bbrc.2016.01.006
更新日期:2016-01-29 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
doi:10.1006/bbrc.1993.1836
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journal_title:Biochemical and biophysical research communications
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更新日期:1995-10-13 00:00:00
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journal_title:Biochemical and biophysical research communications
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更新日期:2020-01-01 00:00:00
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更新日期:1994-09-15 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
doi:10.1006/bbrc.1995.1751
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journal_title:Biochemical and biophysical research communications
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journal_title:Biochemical and biophysical research communications
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doi:10.1006/bbrc.1994.2109
更新日期:1994-08-15 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
doi:10.1016/0006-291x(90)91552-4
更新日期:1990-11-15 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
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更新日期:1987-06-15 00:00:00
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journal_title:Biochemical and biophysical research communications
pub_type: 杂志文章
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更新日期:2008-12-05 00:00:00