Abstract:
:Rheumatoid arthritis, a chronic inflammatory polyarthritis that destroys synovial joints, is associated with systemic as well as local inflammation and with an increased risk of cardiovascular disease and death not fully explained by traditional cardiac risk factors. Statins (HMG-coA reductase inhibitors), medications originally designed to lower cholesterol, have been shown to have powerful effects on decreasing cardiovascular mortality rates in the general and high-risk populations. Not all of this protective benefit appears to be mediated by lowered cholesterol levels. Statins also influence multiple steps in the inflammatory process, including leukocyte migration and adhesion, T-cell stimulation, nitric oxide bioavailability, generation of free radicals, and angiogenesis. Recent studies show that statins may provide mild anti-inflammatory benefit in rheumatoid arthritis, in addition to reducing cardiovascular risk.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Costenbader KH,Coblyn JSdoi
10.1097/01.smj.0000161755.22998.f7subject
Has Abstractpub_date
2005-05-01 00:00:00pages
534-40; quiz 541, 572issue
5eissn
0038-4348issn
1541-8243journal_volume
98pub_type
杂志文章,评审abstract::Mesenteric occlusion is a rare and usually fatal complication of rheumatoid arthritis (RA). We report a patient with RA who had an acute condition of the abdomen, with clinical evidence of perforated bowel confirmed by histologic study. The successful result in this case is attributed to early surgical intervention. A...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198007000-00034
更新日期:1980-07-01 00:00:00
abstract::A 25-year-old white woman was hospitalized with a postpartum psychosis presenting as an affective disorder with the delusion of Capgras. She was treated with electroconvulsive therapy with resolution of her affective and delusional states. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197708000-00012
更新日期:1977-08-01 00:00:00
abstract::Schwannoma arising within breast parenchyma is rare. We report such a case in a 50-year-old woman. The tumor, which measured 7 mm, is the smallest and the only mammographically detected schwannoma of the breast thus far reported. Clinicians should be aware that this benign tumor of breast may simulate a malignant neop...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199602000-00018
更新日期:1996-02-01 00:00:00
abstract::Perinephric and prostatic abscesses may present with protean symptoms and often arise from ascending urinary tract infections. Both abscesses are often caused by uropathogens, and only on rare occasions is the etiology due to methacillin-resistant Staphylococcus aureus (MRSA). Perinephric and prostatic abscesses have ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31802fff6e
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVES:Errors in drug dosing lead to poor patient outcomes and are common in patients with chronic kidney disease (CKD). Because the majority of patients with CKD are being treated by physicians specializing in internal medicine, we studied the awareness and knowledge that internal medicine resident trainees (IMRTs...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000781
更新日期:2018-03-01 00:00:00
abstract::A patient with thioridazine-hydrochloride-associated agranulocytosis is described and eight previously reported cases are reviewed. This complication is most likely due to a direct toxic effect on the bone marrow. As in our case, markers for an immunologically mediated mechanism have not been found. Thioridazine-hydro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197701000-00051
更新日期:1977-01-01 00:00:00
abstract::We retrospectively studied 125 patients treated for carcinoma in situ of the vulva from 1961 through 1984, with follow-up ranging from one to 24 years. Patients' ages ranged from 24 to 90 years, with a mean age of 53 years. Multifocal disease was more common in women under age 40. Pruritus was the most common complain...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198805000-00012
更新日期:1988-05-01 00:00:00
abstract::We have described a case of reversible acute renal failure caused by acute pyelonephritis. In this entity, the kidneys are swollen by an interstitial infiltrate and edema, and white cell tubular casts and microabscesses may be present. Fractional excretion of sodium is high, and nephrotic proteinuria may occur without...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00030
更新日期:1980-03-01 00:00:00
abstract::Sarcoidosis rarely involves the genitourinary system or the spinal cord. This report describes a case of sarcoidosis with a scrotal mass, a mass compressing the spinal cord, and lesions in the liver and spleen. This case illustrates an uncommon manifestation of sarcoidosis, which may mimic disseminated testicular canc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000163306.54629.35
更新日期:2005-09-01 00:00:00
abstract::Reviewed are 200 cases in which endolaryngeal suspension microsurgical procedures were done using intravenous anesthesia and Venturi insufflation oxygenation. Patients included 177 adults and 23 children, ranging in age from 20 months to 88 years. No significant complications were observed. The technic allowed the glo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197607000-00003
更新日期:1976-07-01 00:00:00
abstract:OBJECTIVES:Immunochromatographic urine pneumococcal antigen testing (ICT) has become a common diagnostic tool for those presenting with possible invasive pneumococcal disease. The incidence and clinical impact of ICT false-positivity on hospitalized patients has not been assessed outside of specific patient subpopulati...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182273b82
更新日期:2011-08-01 00:00:00
abstract::Reported is the fifth known case of Addison's disease due to adrenal involvement by North American blastomycosis (Blastomyces dermatitidis infection). The fact that amphotericin B therapy precipitated an addisonian crisis suggests that patients with disseminated blastomycosis should have their adrenal function and res...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197707000-00028
更新日期:1977-07-01 00:00:00
abstract:OBJECTIVES:Clostridium difficile infection (CDI) is the most common healthcare-associated infection in the United States. Clinical practice guidelines for the treatment of CDI were updated in 2010 by the Society for Healthcare Epidemiology of America and the Infectious Diseases Society of America. An institutional guid...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000428
更新日期:2016-03-01 00:00:00
abstract::Asthma is a chronic inflammatory disease in which the genetic predisposition to allergic disease is the strongest identifiable predisposing factor. (1) Optimal outpatient treatment of asthma includes identifying and minimizing exposure to asthma triggers, whether they Me allergens or irritants. When these triggers are...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-07-01 00:00:00
abstract:OBJECTIVES:To determine the comparative impact of the standard Parents as Teachers (PAT) to the nutrition and physical activity enhanced version (PATE) of the perinatal educational curriculum on compliance with infant feeding recommendations and changes in maternal infant feeding knowledge and beliefs. METHODS:Women a...
journal_title:Southern medical journal
pub_type: 杂志文章,随机对照试验
doi:10.14423/SMJ.0000000000001024
更新日期:2019-10-01 00:00:00
abstract::The percutaneous subclavian vein hemodialysis catheter, which is widely used for vascular access in patients with renal failure, can give rise to several complications. Asymptomatic stenosis or occlusion of the subclavian vein due to these catheters can lead to painful arm edema if further dialysis accesses are constr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00004
更新日期:1988-03-01 00:00:00
abstract::Noninvasive positive pressure ventilation (NPPV) has been used in treatment of a variety of clinical conditions, including acute respiratory failure (ARF) due to status asthmaticus. We present the case of a patient admitted with acute exacerbation of asthma who had ARF and required mechanical ventilation. After extuba...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199701000-00017
更新日期:1997-01-01 00:00:00
abstract::I have described two patients who had recurrent spontaneous myoclonic jerking in the alcohol withdrawal state. These movements were distinguishable clinically and electroencephalographically from partial seizures and epilepsia partialis continua. The jerking did not respond to anticonvulsants but resolved as the withd...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198308000-00028
更新日期:1983-08-01 00:00:00
abstract::The risk of suicidal behavior associated with antidepressant treatment is an issue of debate and concern. The US FDA has required that antidepressants carry a black box warning that there may be a risk of suicidal ideations in depressed pediatric patients treated with these medications, and recently extended the warni...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181a918bd
更新日期:2009-07-01 00:00:00
abstract::With the apparent indefinite postponement of the release of chymopapain for lumbar disk disorders, it seems appropriate to review critically the proliferation of proposed methods of management of this common complaint, particularly the numerous exercise regimens which have been set forth as helpful. A critical review ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-197603000-00027
更新日期:1976-03-01 00:00:00
abstract::Two siblings had frequent seizures from the second and third day of life until one week and seven months, respectively. The mother, grandmothers, and three other family members were similarly affected. Known causes of neonatal seizures were excluded. The condition is inherited as an autosomal dominant trait. Its etiol...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198205000-00038
更新日期:1982-05-01 00:00:00
abstract:BACKGROUND:Our objective was to improve breastfeeding initiation rates at an urban medical center. METHODS:A breastfeeding educational program for health care providers was developed and implemented in 1995. The outcome variable of interest was the change in breastfeeding initiation rate during 2 periods, 1993-1994 an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::This paper reports results of a project designed to examine factors related to compliance with referral for follow-up and treatment of cervical dysplasia. Women studied had cervical dysplasia diagnosed by Pap smear between May 1989 and April 1990. These women had regular follow-up at the gynecology clinic of the Reyno...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199201000-00003
更新日期:1992-01-01 00:00:00
abstract::Despite the simplicity, effectiveness, and safety of spinal anesthesia, arachnoiditis can occur as a complication. The cause of this is often unknown, especially since disposable spinal kits are now normally used. It is postulated that an untoward reaction to the anesthesia or chemical contamination was the cause of a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199311000-00026
更新日期:1993-11-01 00:00:00
abstract::We have reported a fatal complication of a therapeutic dose of ipecac syrup administered in a hospital emergency room. This child received 15 ml of ipecac syrup shortly after ingesting one to five tablets of chlorpheniramine maleate (4 mg). A prolonged course of vomiting (more than 24 hours) eventually resulted in gas...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198706000-00031
更新日期:1987-06-01 00:00:00
abstract::The gene for sickle cell disease is carried by 8% of the African-American population in the United States. The primary care physician is often called upon to recognize and treat one of the major sequelae of sickle cell disease--vaso-occlusive pain crisis. An injectable nonsteroidal anti-inflammatory drug has recently ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199208000-00005
更新日期:1992-08-01 00:00:00
abstract::In 1979 more than 54% of women with children less than 18 years old were in the labor force. The purpose of this study was to study the attitudes of pediatricians toward maternal employment and substitute child care arrangements. To survey their attitudes toward maternal employment and substitute child care, we sent a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198406000-00016
更新日期:1984-06-01 00:00:00
abstract::Despite the remarkably low mortality from poisonous snakebites in the United States during the past few years, there has been little improvement in preventing deformities of digits. Using a retrospective study of 207 cases of poisonous snakebite, I present a method that has been highly successful in avoiding deformiti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198506000-00020
更新日期:1985-06-01 00:00:00
abstract::Thoracic nerve root dysfunction (TNRD) manifested as abdominal pain is an infrequently reported condition. We present data on six patients who had chronic intermittent thoracoabdominal pain originating in the back. Diabetes and osteoarthritis of the spine were the chief causes of these symptoms. The electromyogram in ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198802000-00014
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:The number of methicillin-resistant STaphylococcus aureus (MRSA) infections in the hospital setting is increasing but little is known of its prevalence in the community. In a 1986-1987 study, the prevalence in dermatology outpatient clinics was <0.9%. This study reports changes in the same facilities from 19...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199804000-00011
更新日期:1998-04-01 00:00:00