The immunological synapse and Rho GTPases.

Abstract:

:Rho GTPases are molecular switches controlling a broad range of cellular processes including lymphocyte activation. Not surprisingly, Rho GTPases are now recognized as pivotal regulators of antigen-specific T cell activation by APCs and immunological synapse formation. This review summarizes recent advances in our understanding of how Rho GTPase-dependent pathways control T lymphocyte motility, polarization and activation.

authors

Deckert M,Moon C,Le Bras S

doi

10.1007/3-540-27511-8_5

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

61-90

eissn

0070-217X

issn

2196-9965

journal_volume

291

pub_type

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