Decision making, the P3, and the locus coeruleus-norepinephrine system.

Abstract:

:Psychologists and neuroscientists have had a long-standing interest in the P3, a prominent component of the event-related brain potential. This review aims to integrate knowledge regarding the neural basis of the P3 and to elucidate its functional role in information processing. The authors review evidence suggesting that the P3 reflects phasic activity of the neuromodulatory locus coeruleus-norepinephrine (LC-NE) system. They discuss the P3 literature in the light of empirical findings and a recent theory regarding the information-processing function of the LC-NE phasic response. The theoretical framework emerging from this research synthesis suggests that the P3 reflects the response of the LC-NE system to the outcome of internal decision-making processes and the consequent effects of noradrenergic potentiation of information processing.

journal_name

Psychol Bull

journal_title

Psychological bulletin

authors

Nieuwenhuis S,Aston-Jones G,Cohen JD

doi

10.1037/0033-2909.131.4.510

subject

Has Abstract

pub_date

2005-07-01 00:00:00

pages

510-32

issue

4

eissn

0033-2909

issn

1939-1455

pii

2005-08334-002

journal_volume

131

pub_type

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