Natural killer cell activity in patients with pernicious anemia.

abstract：:This study assessed the mucosal antioxidant response during acute (mouse) and chronic (adult human) H. pylori infection and following N-acetylcysteine administration. Antral biopsies were obtained from 44 patients (16 infected, 28 noninfected). Sixty-nine mice were sacrificed after 1 (n = 25), 4 (n = 28), or 6 (n = 16...

journal_title：Digestive diseases and sciences

authors： Matthews GM,Tivey D,Cummins AG,Butler RN

更新日期：2004-08-01 00:00:00

abstract：AIM:The aim of this study was to assess whether patients with colorectal cancer (CRC) are aware of the risk to family members and to test an educational intervention. METHODS:CRC patients were surveyed regarding their cancer, family history, understanding of familial risk of CRC, and knowledge of existing screening gu...

journal_title：Digestive diseases and sciences

authors： Rubin DT,Gandhi RK,Hetzel JT,Kinnear SH,Aronsohn A,Wood G,Yadron N

更新日期：2009-11-01 00:00:00

abstract：:The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...

journal_title：Digestive diseases and sciences

authors： Ohmoto K,Yoshioka N,Tomiyama Y,Shibata N,Takesue M,Yoshida K,Kuboki M,Yamamoto S

更新日期：2006-02-01 00:00:00

abstract：:The authors have developed a primate model for evaluating cytoprotection against alcohol-induced injury in gastric mucosa pretreated with antiulcer agents. In the present study, groups of squirrel monkeys received either a single oral dose of misoprostol (500 or 200 micrograms/kg), cimetidine (3 or 6 mg/kg), placebo, ...

journal_title：Digestive diseases and sciences

authors： Liss RH,Letourneau RJ,Schepis JP

更新日期：1986-02-01 00:00:00

abstract：:We report a case of localized jejunal amyloidosis occurring in a 74-year-old man who experienced an episode of digestive bleeding while he was receiving oral anticoagulation. It illustrates a rare entity, characterized by an endoscopic aspect of polypoid, pseudotumoral formations. Histologically, submucosal connective...

journal_title：Digestive diseases and sciences

authors： Peny MO,Debongnie JC,Haot J,Van Gossum A

更新日期：2000-09-01 00:00:00

abstract：:Bile acids, such as deoxycholic acid (DC), are known to mediate some of their actions by differentially activating various protein kinase C (PKC) isoforms. This study confirms that DC induces apoptosis in gastric epithelial cells through PARP and caspase cascade activation, and examined the role of PKC in DC-induced a...

journal_title：Digestive diseases and sciences

authors： Redlak MJ,Power JJ,Miller TA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Although endoscopic submucosal dissection (ESD)-induced ulcers heal faster and recur less often than non-iatrogenic gastric ulcers, the optimal dosage and duration of proton pump inhibitor treatment for ESD-induced ulcers remain unclear. AIMS:To evaluate the efficacy of half-dose rabeprazole on endoscopic s...

journal_title：Digestive diseases and sciences

authors： Park HJ,Kim HS,Kim BR,Park SY,Hong JH,Jo KW,Kim JW

更新日期：2013-04-01 00:00:00

abstract：:The mechanisms by which Dai-kenchu-to (TJ-100), a kampo medicine, enhances gastrointestinal motility was investigated using isolated guinea pig ileum. TJ-100 induced contractions accompanied by autonomous contraction at a concentration of more than 3 x 10(-4) g/ml in a dose-related manner. The TJ-100-induced ileal con...

journal_title：Digestive diseases and sciences

authors： Satoh K,Hayakawa T,Kase Y,Ishige A,Sasaki H,Nishikawa S,Kurosawa S,Yakabi K,Nakamura T

更新日期：2001-02-01 00:00:00

abstract：:Acid inhibition after proton pump inhibitors in children is variable, and to measure it by a noninvasive method may help to tailor treatment. To study gastric acid inhibition after a single dose of PPI, by measuring urinary acid output (UAO), which decreases as parietal cells release acid into the stomach during a mea...

journal_title：Digestive diseases and sciences

authors： Oderda G,Rapa A,Chiorboli E,Ronchi B,Zavallone A,Strigini L

更新日期：2002-08-01 00:00:00

abstract：:Anorexia nervosa is considered one type of eating disorder that may result in severe malnutrition. Patients with this disorder commonly complain of postprandial nausea, abdominal pain, and distension. We describe the radiologic and motility abnormalities associated with anorexia nervosa in a 21-year-old female. Barium...

journal_title：Digestive diseases and sciences

authors： Buchman AL,Ament ME,Weiner M,Kodner A,Mayer EA

更新日期：1994-02-01 00:00:00

abstract：:Barrett's esophagus (BE) is a well-known premalignant condition that can be associated with the development of dysplasia and adenocarcinoma. In the past, esophagectomy was the standard treatment for patients with BE with high grade dysplasia (HGD) and early cancer (EC). However, esophagectomy is not necessarily the on...

journal_title：Digestive diseases and sciences

authors： Azarm A,Lukolic I,Shukla M,Concha-Parra R,Gress F

更新日期：2012-12-01 00:00:00

abstract：:Autoregulation of blood flow in the denervated, autoperfused dog stomach was studied before and during local intraarterial infusion of histamine. Histamine caused an increase in gastric blood flow and oxygen uptake. The increased oxygen uptake was due entirely to an increased blood flow, ie, oxygen extraction was not ...

journal_title：Digestive diseases and sciences

authors： Perry MA,Murphree D,Granger DN

更新日期：1982-08-01 00:00:00

abstract：:We examined the role of capsaicin-sensitive afferent neurons in pH-dependent gastrin secretion in the rat stomach. The change in serum gastrin levels relative to changes in luminal pH (using omeprazole for luminal alkalization or 0.1 N HCl for luminal acidification) was studied after oral administration of 4% lidocain...

journal_title：Digestive diseases and sciences

authors： Nojima K,Sumii K,Sumii M,Okahara S,Haruma K,Yoshihara M,Kajiyama G

更新日期：2000-06-01 00:00:00

abstract：:Autoimmune hepatitis has two major variant phenotypes in which the features of classical disease are co-mingled with those of primary biliary cirrhosis or primary sclerosing cholangitis. These overlap syndromes lack codified diagnostic criteria, established pathogenic mechanisms, and confident management strategies. T...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:The preferred method for screening asymptomatic people for colorectal cancer (CRC) is colonoscopy, according to the new American guidelines. The aim of our study was to perform a meta-analysis of the prospective cohorts using total colonoscopy for screening this population for CRC. We looked for the diagnosti...

journal_title：Digestive diseases and sciences

authors： Niv Y,Hazazi R,Levi Z,Fraser G

更新日期：2008-12-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

journal_title：Digestive diseases and sciences

authors： Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

更新日期：2008-01-01 00:00:00

abstract：:Gastric antral vascular ectasia was endoscopically diagnosed in seven patients. Pathologic characteristics of this entity were defined retrospectively, by studying endoscopic pinch biopsy slides from these seven patients and antrectomy specimens from five patients. A scoring system was developed, and the seven patient...

journal_title：Digestive diseases and sciences

authors： Gilliam JH 3rd,Geisinger KR,Wu WC,Weidner N,Richter JE

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Minimally invasive interventions for choledocholithiasis are preferable in elderly patients because they tend to have multiple underlying disorders or a decreased activity of daily living. Endoscopic sphincterotomy and endoscopic papillary balloon dilation have been recognized as first-line treatments for ch...

journal_title：Digestive diseases and sciences

authors： Tonozuka R,Itoi T,Sofuni A,Itokawa F,Kurihara T,Tsuchiya T,Ishii K,Tsuji S,Ikeuchi N,Umeda J,Tanaka R,Honjyo M,Mukai S,Fujita M,Moriyasu F

更新日期：2014-09-01 00:00:00

abstract：:The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...

journal_title：Digestive diseases and sciences

authors： Heresbach D,Bretagne JF,Raoul JL,Moisan A,Siproudhis L,Devillers A,Gosselin M

更新日期：1993-09-01 00:00:00

abstract：:Autoimmune hepatitis has a variable clinical phenotype, and the absence of conventional autoantibodies does not preclude its diagnosis or need for treatment. The goals of this review are to describe the frequency and nature of autoantibody-negative autoimmune hepatitis, indicate its outcome after corticosteroid treatm...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2012-03-01 00:00:00

abstract：:The main pancreatic duct epithelium acts as a barrier to the diffusion of molecules from the duct lumen into pancreatic acinar and interstitial tissue. We studied sequential ultrastructural characteristics of the loss of epithelial barrier function in the cat using lanthanum, an electron-opaque tracer, following perfu...

journal_title：Digestive diseases and sciences

authors： Arendt T

更新日期：1991-01-01 00:00:00

abstract：:A new technique for ambulatory manometry of the small intestine with digital storage of signals is presented. Postprandial motility after a 1700-kJ meal and nighttime fasting motility were recorded in 19 healthy young adults. A comprehensive statistical approach was worked out to illuminate the statistical properties ...

journal_title：Digestive diseases and sciences

authors： Husebye E,Skar V,Aalen OO,Osnes M

更新日期：1990-09-01 00:00:00

abstract：:In the United States, more women than men seek health-care services for symptoms of irritable bowel syndrome (IBS). A number of explanations are given for this gender difference including the higher rates of somatic non-gastrointestinal symptoms and increased psychological distress reported by women with IBS. However,...

journal_title：Digestive diseases and sciences

authors： Cain KC,Jarrett ME,Burr RL,Rosen S,Hertig VL,Heitkemper MM

更新日期：2009-07-01 00:00:00

abstract：:This study investigates the varied expression of DNA methyltransferase (DNMT) proteins in gastric cancer (GC) and their relationship with the biological behavior of the tissues. Immunohistochemistry was used to detect the expression of the 3 DNMTs in gastric tissues. We discovered that the positive rates of DNMT1, DNM...

journal_title：Digestive diseases and sciences

authors： Ding WJ,Fang JY,Chen XY,Peng YS

更新日期：2008-08-01 00:00:00

abstract：:Twenty-four patients with chronic active HCV infection, nonresponders to a previous treatment cycle with recombinant interferon-alpha (r-IFNA), underwent retreatment with leukocyte (LE-) IFN-alpha. This was administered at the dose of 3 MU three times a week, for either six months (group A) or 12 months (group B). All...

journal_title：Digestive diseases and sciences

authors： Scotto G,Grimaldi M

更新日期：1998-10-01 00:00:00

abstract：:The perception that chronic hepatitis C is an asymptomatic disease contrasts with many studies that show a strong association between chronic hepatitis C, hepatocellular cancer, and fatal liver disease. In order to resolve these issues, it is logical to directly evaluate the quality of life in patients with chronic he...

journal_title：Digestive diseases and sciences

authors： Carithers RL Jr,Sugano D,Bayliss M

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is common in patients with inflammatory bowel diseases. The vitamin D receptor (VDR) is a nuclear hormone receptor mediating the activity of vitamin D hormone. Our previous studies showed that intestinal epithelial VDR signaling inhibits colitis by protecting the mucosal epithelial barri...

journal_title：Digestive diseases and sciences

authors： Golan MA,Liu W,Shi Y,Chen L,Wang J,Liu T,Li YC

更新日期：2015-07-01 00:00:00

abstract：:We report the findings in two sisters with active cirrhosis and an anti-liver-kidney microsomal antibody (anti-LKM) of the autoimmune type. This unusual disease is characterized by the presence of high levels of antibodies that react with the smooth and rough endoplasmic reticulum of the liver and other tissues. Our p...

journal_title：Digestive diseases and sciences

authors： Buffet C,Homberg JC,Pelletier G,Turner K,Etienne JP

更新日期：1986-11-01 00:00:00

abstract：:The objective of this study was to investigate the effects of types of dialysis treatments on hepatitis C virus infection and the epidemiologic properties of hepatitis C virus (HCV) infection at three Baskent University hospitals, in Ankara, Adana, and Izmir, Turkey, in 655, 326, and 118 patients with end-stage renal ...

journal_title：Digestive diseases and sciences

authors： Selcuk H,Kanbay M,Korkmaz M,Gur G,Akcay A,Arslan H,Ozdemir N,Yilmaz U,Boyacioglu S

更新日期：2006-08-01 00:00:00

abstract：:Factors and mechanisms involved in esophageal mucosal injury and repair are not well known. The aim of this study was to assess the effects of growth factors and prostaglandins on esophageal mucosal cell repair activities. Rabbit esophageal cells were isolated, cultured, and exposed to different growth factors and pro...

journal_title：Digestive diseases and sciences

authors： Jimenez P,Lanas A,Piazuelo E,Esteva F

更新日期：1998-10-01 00:00:00