Abolition of latent inhibition by a single 5 mg dose of d-amphetamine in man.

abstract：:The effects of methylglucamine orotate (MGO) were studied on polygraphic sleep recordings in rats for 8 h per day between 8 a.m. and 4 p.m. MGO (225 mg/kg) was injected intraperitoneally immediately prior to the onset of recording. In the acute experiment, the effect of MGO was compared to pre- and post-drug control d...

journal_title：Psychopharmacology

authors： Wetzel W,Ott T,Matthies HK,Matthies H

更新日期：1984-01-01 00:00:00

abstract：RATIONALE:Flumazenil, a competitive antagonist of benzodiazepine receptors (BZRs), has been used as a probe to detect effects of putative endogenous ligands for BZRs in anxiety. Flumazenil is renowned for its highly inconsistent behavioral effects. OBJECTIVE:To ascertain effects of flumazenil in the social conflict te...

journal_title：Psychopharmacology

authors： Uhlírová L,Sustková-Fiserová M,Krsiak M

更新日期：2004-01-01 00:00:00

abstract：:We examined the effects on sucrose consumption of a dopamine (DA) D2/D3 antagonist (raclopride, 0-0.3 mg/kg), a serotonin 5-HT2/2c antagonist (ritanserin, 0-0.4 mg/kg), and raclopride (0.15 mg/kg) combined with ritanserin (0-0.4 mg/kg). Three different concentrations of sucrose solution (0.7%, 7.0% and 34%) were teste...

journal_title：Psychopharmacology

authors： Montgomery AM,Suri A

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the relationship between zolpidem use and the risk of acute pancreatitis in Taiwan. METHODS:In this population-based case-control study using the database from the Taiwan National Health Insurance Program from 2000 to 2011, we selected 4535 subjects aged 20-84 years ...

journal_title：Psychopharmacology

authors： Lai SW,Lin CL,Liao KF

更新日期：2015-06-01 00:00:00

abstract：RATIONALE:Evidences indicate that methylglyoxal, a highly reactive metabolite of hyperglycemia, can enhance protein glycation, oxidative stress, or inflammation. Mangiferin, a polyphenol compound of C-glucoside, has many beneficial biological activities, including anti-inflammation, anti-oxidation, neuroprotection, cog...

journal_title：Psychopharmacology

authors： Liu YW,Zhu X,Yang QQ,Lu Q,Wang JY,Li HP,Wei YQ,Yin JL,Yin XX

更新日期：2013-08-01 00:00:00

abstract：RATIONALE:Stressful life events are suggested to contribute to the development of various pathologies, such as cardiovascular disorders, whose etiopathogenesis is highly associated with elevated levels of serum amyloid A (SAA) proteins. SAA synthesis in the liver is regulated by a complex network of cytokines acting in...

journal_title：Psychopharmacology

authors： Konstandi M,Sotiropoulos I,Matsubara T,Malliou F,Katsogridaki A,Andriopoulou CE,Gonzalez FJ

更新日期：2019-06-01 00:00:00

abstract：:The benzodiazepine diazepam and the benzodiazepine antagonist Ro 15-1788 were tested alone or in combination for their influence on scopolamine-induced locomotor stimulation in mice. The benzodiazepine antagonist had no effect by itself, but prevented the enhancement of scopolamine-induced locomotor stimulation produc...

journal_title：Psychopharmacology

authors： Sansone M

更新日期：1982-01-01 00:00:00

abstract：:Lithium elicits opposite effects on two behavioural syndromes in rats: enhancement of the 5-HT1A-linked serotonin syndrome and attenuation of the 5-HT2-linked wet dog shakes. The ability of intracerebroventricular (ICV) myo-inositol or forskolin to reverse the enhancement of the serotonin syndrome by lithium was teste...

journal_title：Psychopharmacology

authors： Kofman O,Levin U

更新日期：1995-03-01 00:00:00

abstract：RATIONALE:The hallucinatory effect and potential abuse of salvinorin A, the major ingredient of Salvia divinorum, has not been documented in animals. OBJECTIVE:The effects of salvinorin A on the zebrafish (Danio rerio) model, through its swimming behavior and conditioned place preference (CPP) task, was studied. MATE...

journal_title：Psychopharmacology

authors： Braida D,Limonta V,Pegorini S,Zani A,Guerini-Rocco C,Gori E,Sala M

更新日期：2007-03-01 00:00:00

abstract：RATIONALE:There is evidence that events early in post-weaning life influence brain development and subsequent adult behaviour and therefore play an important role in the causation of certain psychiatric disorders in later life. Exposing rodents to stressors during the juvenile period has been suggested as a model of in...

journal_title：Psychopharmacology

authors： Peleg-Raibstein D,Feldon J

更新日期：2011-03-01 00:00:00

abstract：RATIONALE:Cognitive rehabilitation is now recognized as an important tool in the treatment of schizophrenia, and findings in this area are emerging rapidly. There is a need for a systematic review of the effects of the different training programs. OBJECTIVES:To review quantitatively the controlled studies on cognitive...

journal_title：Psychopharmacology

authors： Krabbendam L,Aleman A

更新日期：2003-09-01 00:00:00

abstract：RATIONALE:The endogenous cannabinoid system is thought to play a role in reinforcement processes. OBJECTIVES:We tested the effects of five doses of the cannabinoid receptor 1 (CB1) antagonist SR141716 [0, 0.3, 1, 3 and 10 mg/kg intraperitoneal (IP)] on intracranial self-stimulation at the level of the median forebrain...

journal_title：Psychopharmacology

authors： Deroche-Gamonet V,Le Moal M,Piazza PV,Soubrié P

更新日期：2001-09-01 00:00:00

abstract：RATIONALE:Antiepileptic drugs are known to produce side effects which may impair driving performance. Performance effects, however, may differ substantially between individual antiepileptic drugs. OBJECTIVE:To compare the effects of carbamazepine, remacemide, and placebo on actual driving performance during a 12-day i...

journal_title：Psychopharmacology

authors： Ramaekers G,Lamers J,Verhey F,Muntjewerff D,Mobbs E,Sanders N,Lewis M,Lockton A

更新日期：2002-01-01 00:00:00

abstract：:Monoamine oxidase inhibitors (MAOIs) are widely accepted as effective antidepressants. Unfortunately their use has been limited by their capacity to potentiate dietary tyramine (the so called "cheese effect") and their interaction with other drugs. The latter poses a particular problem for patients undergoing anaesthe...

journal_title：Psychopharmacology

authors： Hill S,Yau K,Whitwam J

更新日期：1992-01-01 00:00:00

abstract：RATIONALE:Impulsive behavior is associated with both alcohol use disorders and a family history of alcoholism (FHA). One operational definition of impulsive behavior is the stop-signal task (SST) which measures the time needed to stop a ballistic hand movement. OBJECTIVE:Employ functional magnetic resonance imaging (f...

journal_title：Psychopharmacology

authors： Kareken DA,Dzemidzic M,Wetherill L,Eiler W 2nd,Oberlin BG,Harezlak J,Wang Y,O'Connor SJ

更新日期：2013-07-01 00:00:00

abstract：RATIONALE:Ketamine, a well-known general dissociative anesthetic agent that is a non-competitive antagonist of the N-methyl-D-aspartate receptor, perturbs the perception of elapsed time and the expectation of upcoming events. OBJECTIVE:The objective of this study was to determine the influence of ketamine on temporal ...

journal_title：Psychopharmacology

authors： Brulé S,Herlin B,Pouget P,Missal M

更新日期：2021-02-01 00:00:00

abstract：:The present experiment examined effects of nicotine on body weight of male and female rats when Oreo cookies, potato chips, laboratory chow, and water were available. Body weight and eating behavior were measured for 17-day periods before, during, and after nicotine or saline administration. There was an inverse relat...

journal_title：Psychopharmacology

authors： Grunberg NE,Popp KA,Winders SE

更新日期：1988-01-01 00:00:00

abstract：:Phenelzine (PLZ) is a non-selective monoamine oxidase (MAO) inhibitor commonly used to treat depression and panic disorder. In addition to increasing levels of biogenic amines in the brain, PLZ elevates brain levels of the amino acid gamma-aminobutyric acid (GABA; Baker et al. 1991; present study). Given the extensive...

journal_title：Psychopharmacology

authors： Parent MB,Habib MK,Baker GB

更新日期：1999-03-01 00:00:00

abstract：RATIONALE:Fluoxetine improves affect in clinical syndromes such as depression and premenstrual dysphoric disorder. Little is known about fluoxetine's influence on mood changes after quitting smoking, which often resemble sub-clinical depression. OBJECTIVES:The present study, a re-analysis of previously published data ...

journal_title：Psychopharmacology

authors： Cook JW,Spring B,McChargue DE,Borrelli B,Hitsman B,Niaura R,Keuthen NJ,Kristeller J

更新日期：2004-04-01 00:00:00

abstract：:The present study employed an animal model of drug relapse in which previously extinguished heroin self-administration behavior was reinstated following a single reinforced trial. Male albino rats were trained to traverse a straight-alley for a reinforcer consisting of a single IV injection of 0.06 mg/kg diacetylmorph...

journal_title：Psychopharmacology

authors： Ettenberg A,MacConell LA,Geist TD

更新日期：1996-04-01 00:00:00

abstract：RATIONALE:Cannabis (CB) use and dependence are associated with regionally specific alterations to brain circuitry and substantial psychosocial impairment. OBJECTIVES:The objective of this study was to investigate the association between CB use and dependence, and the volumes of brain regions critically involved in goa...

journal_title：Psychopharmacology

authors： Chye Y,Solowij N,Suo C,Batalla A,Cousijn J,Goudriaan AE,Martin-Santos R,Whittle S,Lorenzetti V,Yücel M

更新日期：2017-07-01 00:00:00

abstract：:A group of 14 schizophrenics who remained symptomatic after neuroleptic treatment received either 0.02 mcg/kg CCK-8 or saline placebo intravenously. Thereafter, 13 received the alternative infusion as a crossover treatment. A second group of 16 such patients received 0.04 mcg/kg CCK-8 or saline intravenously and, ther...

journal_title：Psychopharmacology

authors： Peselow E,Angrist B,Sudilovsky A,Corwin J,Siekierski J,Trent F,Rotrosen J

更新日期：1987-01-01 00:00:00

abstract：INTRODUCTION:The comparative effects of a newly described specific alpha7 nAChR partial agonist, S 24795, and a cholinesterase inhibitor, donepezil, currently used as a symptomatic Alzheimer's disease treatment were studied in two mouse models of aging-related memory deficits. MATERIALS AND METHODS:We employed radial ...

journal_title：Psychopharmacology

authors： Marighetto A,Valerio S,Desmedt A,Philippin JN,Trocmé-Thibierge C,Morain P

更新日期：2008-04-01 00:00:00

abstract：:In the conditioned reinforcement paradigm, animals learn a new instrumental response reinforced solely by conditioned reward (a stimulus that has previously been associated with primary reward). It has been shown that psychostimulants potentiate responding for conditioned reward and there is evidence that the nucleus ...

journal_title：Psychopharmacology

authors： Kelley AE,Delfs JM

更新日期：1991-01-01 00:00:00

abstract：:The effect of two subcutaneous injections of 0.6 mg nicotine, administered 40 min apart, was compared with placebo in four non-smoking subjects in a counter-balanced double-blind crossover design. The nicotine injections produced mean peak plasma nicotine concentrations of 5.3 ng/ml 10 min after the first injection an...

journal_title：Psychopharmacology

authors： Foulds J,McSorley K,Sneddon J,Feyerabend C,Jarvis MJ,Russell MA

更新日期：1994-06-01 00:00:00

abstract：RATIONALE:Cortical gamma-aminobutyric acid (GABA)ergic neurons contribute to the orchestration of pyramidal neuron population firing as follows: (1) by releasing GABA on GABA(A) and GABA(B) receptors, (2) by releasing reelin in the proximity of integrin receptors located on cortical pyramidal neuron dendritic spines, a...

journal_title：Psychopharmacology

authors： Guidotti A,Auta J,Davis JM,Dong E,Grayson DR,Veldic M,Zhang X,Costa E

更新日期：2005-07-01 00:00:00

abstract：:The purpose of this study was to compare the subchronic, low-dose effects of clozapine with those of olanzapine in a learned behavioral task previously shown to distinguish between clozapine and haloperidol with acute and subchronic treatment regimes. Rats were trained to use a single forelimb to press a force-recordi...

journal_title：Psychopharmacology

authors： Stanford JA,Fowler SC

更新日期：1997-08-01 00:00:00

abstract：:6-Hydroxydopamine (6OH-DA) pretreatment increased the aggressive behavior induced by marihuana in REM sleep-deprived rats. Brain catecholamine assays revealed that 6OH-DA depleted popamine (DA) and norepinephrine (NE) to a different extent, increasing the DA/NE ratio. Intraventricular injection of NE significantly dec...

journal_title：Psychopharmacology

authors： Musty RE,Lindsey CJ,Carlini EA

更新日期：1976-07-28 00:00:00

abstract：RATIONALE:Previous work has shown that clozapine suppressed tacrine-induced jaw movements at lower doses than those required for suppression of lever pressing. OBJECTIVE:The novel atypical antipsychotic olanzapine was assessed in these behavioral tests. METHODS:The effect of acute olanzapine on the suppression of tac...

journal_title：Psychopharmacology

authors： Trevitt JT,Carlson BB,Salamone JD

更新日期：1999-08-01 00:00:00

abstract：RATIONALE:Non-contingent chronic nicotine exposure procedures have evolved rapidly in recent years, culminating in electronic nicotine delivery systems (ENDS or e-cigarettes) to deliver vaporized drugs to rodents in standard housing chambers. OBJECTIVES:The aim of the current work was to use ENDS to test concentration...

journal_title：Psychopharmacology

authors： Montanari C,Kelley LK,Kerr TM,Cole M,Gilpin NW

更新日期：2020-03-01 00:00:00