Expression and localization of aquaporin-5 in the epithelial ovarian tumors.

abstract：OBJECTIVE:We assessed the antineoplastic effect and adverse reactions of paclitaxel monotherapy with paclitaxel 210 mg/m(2) given every 3 weeks by 3-h infusion on patients with endometrial cancer given as a 3-h infusion. METHODS:This study was a multi-center, open-label phase II clinical trial of paclitaxel 210 mg/m(2...

journal_title：Gynecologic oncology

authors： Hirai Y,Hasumi K,Onose R,Kuramoto H,Kuzuya K,Hatae M,Ochiai K,Nozawa S,Noda K

更新日期：2004-08-01 00:00:00

abstract：UNLABELLED:Despite the publication of two dozen observational epidemiological studies investigating the association between recreational physical activity (RPA) and epithelial ovarian cancer (EOC) risk and survival over the past two decades, taken collectively, data from retrospective and prospective studies are mixed ...

journal_title：Gynecologic oncology

authors： Cannioto RA,Moysich KB

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVE:Given the paucity of data regarding the patterns of metastasis from ovarian sex cord-stromal tumors (SCSTs), we sought to determine the risk of lymph node metastasis in patients with SCSTs. METHODS:A retrospective chart review was performed after clinical and pathology databases were queried for ovarian SCST...

journal_title：Gynecologic oncology

authors： Brown J,Sood AK,Deavers MT,Milojevic L,Gershenson DM

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:To assess the relationship between low-dose tamoxifen, usage and endometrial cancer in breast cancer patients. METHODS:In this case-control study, the records of the 1017 patients treated at Wilford Hall Medical Center for primary breast cancer between 1978 and 1989 were reviewed. Dose and duration of tamoxi...

journal_title：Gynecologic oncology

authors： Robinson DC,Bloss JD,Schiano MA

更新日期：1995-11-01 00:00:00

abstract：:Ovarian cancer is the leading cause of gynecologic cancer deaths in the U.S. The concept of intraperitoneal drug delivery for therapy of intraperitoneal cancers, such as ovarian cancer, arose in the 1960s. The field of intraperitoneal cisplatin therapy for ovarian cancer was initiated in the late 1970s and early 1980s...

journal_title：Gynecologic oncology

authors： Alberts DS,Markman M,Muggia F,Ozols RF,Eldermire E,Bookman MA,Chen T,Curtin J,Hess LM,Liebes L,Young RC,Trimble E

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:To analyze the survival of women with malignant, mixed mullerian tumors of the ovary (OMMMT) compared to women with epithelial ovarian cancer (EOC). METHODS:Data from the Surveillance, Epidemiology and End Results (SEER) Program on 14025 women diagnosed with primary invasive ovarian cancer between 1988 and 1...

journal_title：Gynecologic oncology

authors： Barnholtz-Sloan JS,Morris R,Malone JM Jr,Munkarah AR

更新日期：2004-05-01 00:00:00

abstract：:The treatment of early vulvar carcinoma has moved toward less radical surgery with reconstruction. This report describes our preliminary experience with a mons pubis flap that is simple and appears safe, reliable, and gives excellent cosmetic and functional results following radical hemivulvectomy. Four patients have ...

journal_title：Gynecologic oncology

authors： Potkul RK,Barnes WA,Barter JF,Delgado G,Spear SL

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this work was to evaluate the ability of testing for high-risk human papillomavirus (HPV) types using the hybrid capture technique to predict the presence of cervical intraepithelial neoplasia (CIN) II,III in patients with repeated atypical squamous cells of undetermined significance (ASCUS) an...

journal_title：Gynecologic oncology

authors： Fait G,Kupferminc MJ,Daniel Y,Geva E,Ron IG,Lessing JB,Bar-Am A

更新日期：2000-11-01 00:00:00

abstract：:The Patient Protection and Affordable Care Act (ACA) was signed into law by President Barack Obama in 2010. While initial implementation of the law began shortly thereafter, the full implementation will take place over the next few years. With respect to cancer care, the act was intended to make care more accessible, ...

journal_title：Gynecologic oncology

authors： Duska LR,Engelhard CL

更新日期：2013-06-01 00:00:00

abstract：:Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of en...

journal_title：Gynecologic oncology

authors： Willén R,Békássy,Carlén B,Bozoky B,Cajander S

更新日期：1999-08-01 00:00:00

abstract：:Results of treatment and potential prognostic factors in 54 patients with clinical stage II endometrial carcinoma were analyzed. During the period analyzed, three different treatment techniques were used. The highest cure rate (70.6%) was observed in patients treated with simple hysterectomy and bilateral salpingo-oop...

journal_title：Gynecologic oncology

authors： Andersen ES

更新日期：1990-08-01 00:00:00

abstract：:Adriamycin (50 mg/m2) and cis-diamminedichloroplatinum (50 mg/m2) were administered every 21 days to treat metastatic endometrial adenocarcinoma. This regimen resulted in three responses (one complete and two partial) in nine women (33%). Most patients had moderate or severe hematologic and gastrointestinal toxicity. ...

journal_title：Gynecologic oncology

authors： Seltzer V,Vogl SE,Kaplan BH

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:Recent randomized controlled data suggest that neoadjuvant chemotherapy (NACT) with interval debulking (ID) may produce similar overall survival and progression free survival compared to standard primary cytoreduction followed by chemotherapy. The object of our study was to assess current patterns of care amo...

journal_title：Gynecologic oncology

authors： Dewdney SB,Rimel BJ,Reinhart AJ,Kizer NT,Brooks RA,Massad LS,Zighelboim I

更新日期：2010-10-01 00:00:00

abstract：:Primary lymphoma of the cervix is very rare. A case report is presented and 24 cases published in the English literature are reviewed. Evaluation, staging, treatment, and prognosis of this rare tumor are discussed. ...

journal_title：Gynecologic oncology

authors： Mann R,Roberts WS,Gunasakeran S,Tralins A

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:In this phase II study the efficacy and toxicity of an alternating chemotherapy regimen was examined in platinum-resistant relapsed epithelial ovarian cancer (EOC) patients. METHODS:Forty-five patients with platinum-refractory/resistant relapsed EOC, previously treated with carboplatin+paclitaxel+/-epirubici...

journal_title：Gynecologic oncology

authors： Pectasides D,Pectasides E,Papaxoinis G,Psyrri A,Pliarchopoulou K,Koumarianou A,Macheras A,Athanasas G,Xiros N,Economopoulos T

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:CD4(+)CD25(+) regulatory T-cells (Tregs), that express the transcription factor FOXP3, suppress effector T-cell populations and can enable tumour cells to evade the host immune response. In this study, we investigated the numbers of FOXP3(+) Tregs in the normal and malignat endometrium and examined potential...

journal_title：Gynecologic oncology

authors： Giatromanolaki A,Bates GJ,Koukourakis MI,Sivridis E,Gatter KC,Harris AL,Banham AH

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The role of radiotherapy for recurrent or residual granulosa cell tumor of the ovary (GCTO) is controversial. One reason for this controversy may be that most published studies on this topic have not utilized sectional imaging to assess response to radiotherapy. We report on three cases of recurrent or resid...

journal_title：Gynecologic oncology

authors： E C,Samant R,Fung MF,Le T,Hopkins L,Senterman M

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVE:Human papillomavirus (HPV) infection is the primary cause of cervical cancer. HPV-mediated immune alterations are known to play crucial roles in determining viral persistence and host cell transformation. We sought to thoroughly understand HPV-directed immune alterations in cervical cancer by exploring public...

journal_title：Gynecologic oncology

authors： Chen L,Luan S,Xia B,Liu Y,Gao Y,Yu H,Mu Q,Zhang P,Zhang W,Zhang S,Wei G,Yang M,Li K

更新日期：2018-05-01 00:00:00

abstract：:In a prospective, randomized, double-blind trial the combination betamethasone-dixyrazine was compared with high-dose metoclopramide as antiemetic treatment during combination chemotherapy (melphalan-doxorubicin and cisplatin) of ovarian carcinoma. Of 40 evaluable patients, 15 (38%) had previous experience with chemot...

journal_title：Gynecologic oncology

authors： Sorbe B,Hallén C

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVE:Describing the pattern of and reasons for post-operative tumor residuals in patients with advanced epithelial ovarian cancer (AOC) operated in a specialized gynecologic cancer center following a strategy of maximum upfront debulking followed by systemic chemotherapy. METHODS:All consecutive AOC-patients trea...

journal_title：Gynecologic oncology

authors： Heitz F,Harter P,Alesina PF,Walz MK,Lorenz D,Groeben H,Heikaus S,Fisseler-Eckhoff A,Schneider S,Ataseven B,Kurzeder C,Prader S,Beutel B,Traut A,du Bois A

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:The hepatocyte growth factor (HGF) receptor c-Met plays an important role in tumor dissemination by activating mitogenic signaling pathways. The goal of this study was to investigate immunohistochemical (IHC) staining patterns of HGF and c-Met in endometrioid endometrial cancer (EC) and uterine serous cancer ...

journal_title：Gynecologic oncology

authors： Bishop EA,Lengyel ER,Yamada SD,Montag A,Temkin SM

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:In the US, second non-ocular malignancies are the primary cause of death in retinoblastoma survivors with the germline RB1 mutation. Soft tissue sarcomas are one of the most likely malignancies to pose a risk to these patients, with leiomyosarcoma (LMS) being the most common subtype. As our cohort is followed...

journal_title：Gynecologic oncology

authors： Francis JH,Kleinerman RA,Seddon JM,Abramson DH

更新日期：2012-02-01 00:00:00

abstract：:Sialosyl-Tn (S-Tn) antigen, a cancer-related antigen, was expressed in 56.3% (36 of 64 cases) of the common epithelial carcinoma tissues. This antigen was moderately to strongly expressed in 83.3% (15 of 18 cases) of the mucinous adenocarcinomas. In contrast, it was weakly expressed in 31.3% (5 of 16 cases) of the ser...

journal_title：Gynecologic oncology

authors： Ryuko K,Iwanari O,Kitao M,Moriwaki S

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:To examine the differentially expressed cancer-related genes in two morphologically different uterine cervical carcinoma cell lines derived from the same patient by an Affymetrix Human Cancer G110 Array carrying 1700 cancer-associated genes. In addition, to investigate specific gene expression depending on hist...

journal_title：Gynecologic oncology

authors： Fujimoto T,Nishikawa A,Iwasaki M,Akutagawa N,Teramoto M,Kudo R

更新日期：2004-05-01 00:00:00

abstract：:Immunotherapy (IO) is an important new pillar in the treatment of solid tumors, and the integration of IO agents with chemotherapy, targeted therapy, surgery and radiation has yet to be defined. As preclinical and clinical studies have described synergistic activity with the combination of radiation and immunotherapy,...

journal_title：Gynecologic oncology

authors： Lee L,Matulonis U

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Some authors have recommended the use of diagnostic laparoscopy as a pretreatment assessment step for conservative hormonal treatment in young women with endometrial cancer. The aim of this study was to determine the incidence of synchronous primary cancer of the endometrium and ovary in young women. METHODS...

journal_title：Gynecologic oncology

authors： Song T,Seong SJ,Bae DS,Suh DH,Kim DY,Lee KH,Lim MC,Lee TS

更新日期：2013-12-01 00:00:00

abstract：:After standard management of stage III-IV ovarian cancer patients by surgical reduction of tumor mass and subsequent cisplatin-based combination chemotherapy, eradication of residual intraabdominal disease remains a major clinical problem. In an effort to increase response to therapy without adding marrow toxicity, af...

journal_title：Gynecologic oncology

authors： Campora E,Bruzzone M,Chiara S,Alama A,Iskra L,Carnino F,Parodi S,Foglia G,Ragni N,Rosso R

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:Vaccination of young women (15-25 years of age) against human papillomavirus (HPV) has been shown to be very efficacious in preventing the development of moderate or severe cervical precancerous lesions associated with HPV-16 or -18. As the highest rates of new infections with high-risk (i.e., oncogenic) HPV ...

journal_title：Gynecologic oncology

authors： Castellsagué X,Schneider A,Kaufmann AM,Bosch FX

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to evaluate the effects of single fractions of 10 Gy pelvic irradiation for palliation and life prolongation in patients with cancer of the uterine cervix or corpus. METHODS:A retrospective analysis was performed on 37 cervical cancer and 27 corpus cancer patients treated in the pe...

journal_title：Gynecologic oncology

authors： Onsrud M,Hagen B,Strickert T

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy, feasibility and safety of image-based, inversely and adaptively planned high-dose rate interstitial brachytherapy (HDR-ISBT) to treat advanced primary or recurrent gynecologic malignancy in a single implant, three-consecutive-day regimen. METHODS:Clinical demographics and outcome da...

journal_title：Gynecologic oncology

authors： Hanania AN,Myers P,Yoder AK,Bulut A,Henry Yu Z,Eraj S,Bowers J,Bonnen MD,Echeverria A,Hall TR,Anderson ML,Ludwig M

更新日期：2019-02-01 00:00:00