Functional conservation of the fruitless male sex-determination gene across 250 Myr of insect evolution.

abstract：:The chemokine receptor CCR5 can serve as a coreceptor for M-tropic HIV-1 infection and both M-tropic and T-tropic SIV infection. We sequenced the entire CCR5 gene from 10 nonhuman primates: Pongo pygmaeus, Hylobates leucogenys, Trachypithecus francoisi, Trachypithecus phayrei, Pygathrix nemaeus, Rhinopithecus roxellan...

journal_title：Molecular biology and evolution

authors： Zhang YW,Ryder OA,Zhang YP

更新日期：1999-09-01 00:00:00

abstract：:Analyses of diverse eukaryotes reveal that genomes are dynamic, sometimes dramatically so. In numerous lineages across the eukaryotic tree of life, DNA content varies within individuals throughout life cycles and among individuals within species. Discovery of examples of genome dynamism is accelerating as genome seque...

journal_title：Molecular biology and evolution

authors： Parfrey LW,Lahr DJ,Katz LA

更新日期：2008-04-01 00:00:00

abstract：:Sponges (Porifera) are among the simplest living and the earliest branching metazoans. They hold a pivotal role for studying genome evolution of the entire metazoan branch, both as an outgroup to Eumetazoa and as the closest branching phylum to the common ancestor of all multicellular animals (Urmetazoa). In order to ...

journal_title：Molecular biology and evolution

authors： Harcet M,Roller M,Cetković H,Perina D,Wiens M,Müller WE,Vlahovicek K

更新日期：2010-12-01 00:00:00

abstract：:Influenza A viruses from wild aquatic birds, their natural reservoir species, are thought to have reached a form of stasis, characterized by low rates of evolutionary change. We tested this hypothesis by estimating rates of nucleotide substitution in a diverse array of avian influenza viruses (AIV) and allowing for ra...

journal_title：Molecular biology and evolution

authors： Chen R,Holmes EC

更新日期：2006-12-01 00:00:00

abstract：:Adaptation of a complex trait often requires the accumulation of many modifications to finely tune its underpinning molecular components to novel environmental requirements. The investigation of cis-acting regulatory modifications can be used to pinpoint molecular systems partaking in such complex adaptations. Here, w...

journal_title：Molecular biology and evolution

authors： He F,Arce AL,Schmitz G,Koornneef M,Novikova P,Beyer A,de Meaux J

更新日期：2016-08-01 00:00:00

abstract：:As the relic of the ancient Champa Kingdom, the Cham people represent the major Austronesian speakers in Mainland Southeast Asia (MSEA) and their origin is evidently associated with the Austronesian diffusion in MSEA. Hitherto, hypotheses stemming mainly from linguistic and cultural viewpoints on the origin of the Cha...

journal_title：Molecular biology and evolution

authors： Peng MS,Quang HH,Dang KP,Trieu AV,Wang HW,Yao YG,Kong QP,Zhang YP

更新日期：2010-10-01 00:00:00

abstract：:The question of multiple sequence alignment quality has received much attention from developers of alignment methods. Less forthcoming, however, are practical measures for addressing alignment quality issues in real life settings. Here, we present a simple methodology to help identify and quantify the uncertainties in...

journal_title：Molecular biology and evolution

authors： Landan G,Graur D

更新日期：2007-06-01 00:00:00

abstract：:We describe here a case of homologous introns containing homologous open reading frames (ORFs) that are inserted at the same site in the large subunit (LSU) rRNA gene of different organelles in distantly related organisms. We show that the chloroplast LSU rRNA gene of the green alga Chlamydomonas pallidostigmatica con...

journal_title：Molecular biology and evolution

authors： Turmel M,Côté V,Otis C,Mercier JP,Gray MW,Lonergan KM,Lemieux C

更新日期：1995-07-01 00:00:00

abstract：:The brine shrimp Artemia has three extracellular hemoglobins (Hbs) that are developmentally expressed and exhibit distinct oxygen-binding characteristics (Heip, Moens, and Kondo 1978; Heip et al. 1978 ). These Hbs are composed of two polymers, each of which comprises nine covalently linked globin domains. Although the...

journal_title：Molecular biology and evolution

authors： Vandenberg CJ,Matthews CM,Trotman CN

更新日期：2002-08-01 00:00:00

abstract：:Lichen-forming fungi, in symbiotic associations with algae, frequently have nuclear small subunit ribosomal DNA (SSU rDNA) longer than the 1,800 nucleotides typical for eukaryotes. The lichen-forming ascomycetous fungus Lecanora dispersa contains insertions at eight distinct positions of its SSU rDNA; the lichen-formi...

journal_title：Molecular biology and evolution

authors： Gargas A,DePriest PT,Taylor JW

更新日期：1995-03-01 00:00:00

abstract：:Due to its speed, the distance approach remains the best hope for building phylogenies on very large sets of taxa. Recently (R. Desper and O. Gascuel, J. Comp. Biol. 9:687-705, 2002), we introduced a new "balanced" minimum evolution (BME) principle, based on a branch length estimation scheme of Y. Pauplin (J. Mol. Evo...

journal_title：Molecular biology and evolution

authors： Desper R,Gascuel O

更新日期：2004-03-01 00:00:00

abstract：:We investigated global patterns of variation in 157 whole-genome sequences of Vibrio parahaemolyticus, a free-living and seafood associated marine bacterium. Pandemic clones, responsible for recent outbreaks of gastroenteritis in humans, have spread globally. However, there are oceanic gene pools, one located in the o...

journal_title：Molecular biology and evolution

authors： Cui Y,Yang X,Didelot X,Guo C,Li D,Yan Y,Zhang Y,Yuan Y,Yang H,Wang J,Wang J,Song Y,Zhou D,Falush D,Yang R

更新日期：2015-06-01 00:00:00

abstract：:It is widely accepted that evolutionary changes in conserved developmental signaling pathways play an important role in morphological evolution. However, few in silico studies were interested in tracking such changes in a signaling pathway. The Ectodysplasin (EDA) pathway provides an opportunity to fill this gap becau...

journal_title：Molecular biology and evolution

authors： Pantalacci S,Chaumot A,Benoît G,Sadier A,Delsuc F,Douzery EJ,Laudet V

更新日期：2008-05-01 00:00:00

abstract：:A novel algorithm, GS-Aligner, that uses bit-level operations was developed for aligning genomic sequences. GS-Aligner is efficient in terms of both time and space for aligning two very long genomic sequences and for identifying genomic rearrangements such as translocations and inversions. It is suitable for aligning ...

journal_title：Molecular biology and evolution

authors： Shih AC,Li WH

更新日期：2003-08-01 00:00:00

abstract：:In order to investigate divergence of immune regulation among Drosophila species, we have engaged in a study of innate immune function in F1 hybrids of Drosophila melanogaster and D. simulans. If pathways have diverged between the species such that incompatibilities have arisen between interacting components of the im...

journal_title：Molecular biology and evolution

authors： Hill-Burns EM,Clark AG

更新日期：2010-11-01 00:00:00

abstract：:Rearrangements of mitochondrial DNA gene order have been suggested as a tool for defining the pattern of evolutionary divergence in arthropod taxa. We have employed a combination of highly conserved insect-based polymerase chain reaction (PCR) primers with long-PCR to survey 14 noninsect arthropods for mitochondrial g...

journal_title：Molecular biology and evolution

authors： Roehrdanz RL,Degrugillier ME,Black WC 4th

更新日期：2002-06-01 00:00:00

abstract：:The mitochondrial inner and outer membranes are composed of a variety of integral membrane proteins, assembled into the membranes posttranslationally. The small translocase of the inner mitochondrial membranes (TIMs) are a group of approximately 10 kDa proteins that function as chaperones to ferry the imported protein...

journal_title：Molecular biology and evolution

authors： Gentle IE,Perry AJ,Alcock FH,Likić VA,Dolezal P,Ng ET,Purcell AW,McConnville M,Naderer T,Chanez AL,Charrière F,Aschinger C,Schneider A,Tokatlidis K,Lithgow T

更新日期：2007-05-01 00:00:00

abstract：:Signaling peptides enable communication between cells, both within and between individuals, and are therefore key to the control of complex physiological and behavioral responses. Since their small sizes prevent direct transmission to secretory pathways, these peptides are often produced as part of a larger polyprotei...

journal_title：Molecular biology and evolution

authors： Rogers DW,McConnell E,Miller EL,Greig D

更新日期：2017-12-01 00:00:00

abstract：:It has recently been observed by Ho et al. (Ho SYW, Phillips MJ, Cooper A, Drummond AJ. 2005. Time dependency of molecular rate estimates and systematic overestimation of recent divergence times. Mol Biol Evol. 22(7):1561-1568) that apparent rates of molecular evolution increase when measured over short timespans. I i...

journal_title：Molecular biology and evolution

authors： Woodhams M

更新日期：2006-12-01 00:00:00

abstract：:In chickens, there is a single functional gene (VH1) coding for the heavy chain variable region of immunoglobulins, and immunoglobulin diversity is generated by gene conversion of the VH1 gene by many variable region pseudogenes (psi VH's) that exist on the 5' side of the VH1 gene. To understand the evolution of this ...

journal_title：Molecular biology and evolution

authors： Ota T,Nei M

更新日期：1995-01-01 00:00:00

abstract：:Standard methods of phylogenetic reconstruction are based on models that assume homogeneity of nucleotide composition among taxa. However, this assumption is often violated in biological data sets. In this study, we examine possible effects of nucleotide heterogeneity among lineages on the phylogenetic reconstruction ...

journal_title：Molecular biology and evolution

authors： Herbeck JT,Degnan PH,Wernegreen JJ

更新日期：2005-03-01 00:00:00

abstract：:Fish mitochondrial genome (mitogenome) data form a fundamental basis for revealing vertebrate evolution and hydrosphere ecology. Here, we report recent functional updates of MitoFish, which is a database of fish mitogenomes with a precise annotation pipeline MitoAnnotator. Most importantly, we describe implementation ...

journal_title：Molecular biology and evolution

authors： Sato Y,Miya M,Fukunaga T,Sado T,Iwasaki W

更新日期：2018-06-01 00:00:00

abstract：:We review all instances in which the nuclear 5S rRNA genes of fungi, protist, nematode, and arthropod species have been reported to be linked to the tandemly repeated units of the rDNA, trans-spliced leader, and histone multigene families. The evolution of these gene arrangements is analyzed by mapping them to indepen...

journal_title：Molecular biology and evolution

authors： Drouin G,de Sá MM

更新日期：1995-05-01 00:00:00

abstract：:Previous studies have shown that splicing efficiency, and thus maturation of pre-mRNA, depends on the correct folding of the RNA molecule into a secondary or higher order structure. When disrupted by a mutation, aberrant folding may result in a lower splicing efficiency. However, the structure can be restored by a sec...

journal_title：Molecular biology and evolution

authors： Piskol R,Stephan W

更新日期：2008-11-01 00:00:00

abstract：:DNA fingerprinting exhibits multilocus genotypes of individuals, detected by the use of a single multilocus probe. Consequently, population data on DNA fingerprinting do not provide a complete characterization of the genetic variation in terms of allele-frequency distributions, since neither the number of loci nor the...

journal_title：Molecular biology and evolution

authors： Jin L,Chakraborty R

更新日期：1994-01-01 00:00:00

abstract：:The Sp family of transcription factors binds GC-rich DNA sequences. The ubiquitously expressed Sp1 and Sp3 have been well characterized in mammals. Presented here is the characterization of the only Sp protein expressed in the liver or heart tissue of the teleost fish Fundulus heteroclitus. This protein, fSp3, is most...

journal_title：Molecular biology and evolution

authors： Kolell KJ,Crawford DL

更新日期：2002-03-01 00:00:00

abstract：:Much of evolutionary change is mediated at the level of gene expression, yet our understanding of regulatory evolution remains unsatisfying. In light of recent data indicating that transcription factor binding sites undergo substantial turnover between species, we attempt to quantify the process of binding site turnov...

journal_title：Molecular biology and evolution

authors： Dermitzakis ET,Bergman CM,Clark AG

更新日期：2003-05-01 00:00:00

abstract：:The evolution of amniotes has involved major molecular innovations in the epidermis. In particular, distinct structural proteins that undergo covalent cross-linking during cornification of keratinocytes facilitate the formation of mechanically resilient superficial cell layers and help to limit water loss to the envir...

journal_title：Molecular biology and evolution

authors： Strasser B,Mlitz V,Hermann M,Rice RH,Eigenheer RA,Alibardi L,Tschachler E,Eckhart L

更新日期：2014-12-01 00:00:00

abstract：:The origin of novel traits is recognized as an important process underlying many major evolutionary radiations. We studied the genetic basis for the evolution of haustoria, the novel feeding organs of parasitic flowering plants, using comparative transcriptome sequencing in three species of Orobanchaceae. Around 180 g...

journal_title：Molecular biology and evolution

authors： Yang Z,Wafula EK,Honaas LA,Zhang H,Das M,Fernandez-Aparicio M,Huang K,Bandaranayake PC,Wu B,Der JP,Clarke CR,Ralph PE,Landherr L,Altman NS,Timko MP,Yoder JI,Westwood JH,dePamphilis CW

更新日期：2015-03-01 00:00:00

abstract：:Phylogenetic inference from genome-wide data (phylogenomics) has revolutionized the study of evolution because it enables accounting for discordance among evolutionary histories across the genome. To this end, summary methods have been developed to allow accurate and scalable inference of species trees from gene trees...

journal_title：Molecular biology and evolution

authors： Zhang C,Scornavacca C,Molloy EK,Mirarab S

更新日期：2020-11-01 00:00:00