Novel heterogeneity of the leucocyte common antigen (CD45): disulfide-bound heterodimers between CD45 and an 80 kDa polypeptide.

abstract：:The spontaneous migration in vitro, production of T cell migration inhibitory factor (TIF) and the response to TIF of OKT4+ and OKT8+ human T cell subsets were studied. The OKT4+ lymphocytes migrated far better than the OKT8+ cells although the movement of both subsets was comparably inhibited by TIF. The OKT8+ subset...

journal_title：Immunology letters

authors： Kowalczyk D,Pryjma J,Zembala M

更新日期：1986-08-01 00:00:00

abstract：:Two cell lines producing monoclonal antibodies have been established from peripheral blood of a negative Rhesus blood donor which has been immunized with positive Rhesus red blood cells. Two monoclonal antibodies Co II 8.8 and Co II 7.12 have been selected. Both are IgG1 antibodies, but recognize different epitopes on...

journal_title：Immunology letters

authors： Paire J,Monestier M,Rigal D,Martel F,Desgranges C

更新日期：1986-09-01 00:00:00

abstract：:The 19S proteasome regulatory particle plays a critical role in cellular proteolysis. However, emerging evidence suggests roles for 19S proteasome subunits in regulating yeast and mammalian transcription. It has been previously shown that Sug1 is important for the transcription of MHC II molecules. We report here that...

journal_title：Immunology letters

authors： Inostroza-Nieves Y,Venkatraman P,Zavala-Ruiz Z

更新日期：2012-09-01 00:00:00

abstract：:The T cell receptor of gamma delta is normally expressed on a small percentage of peripheral lymphocytes. Although the role of gamma delta T cells in the physiologic immune response is still unknown, there is accumulating evidence that gamma delta T cells may participate in the immune response to mycobacterial and oth...

journal_title：Immunology letters

authors： Ho M,Webster HK,Tongtawe P,Pattanapanyasat K,Weidanz WP

更新日期：1990-08-01 00:00:00

abstract：:Pretreatment of murine bone marrow-derived macrophages with wheat germ agglutinin (WGA) and concanavalin A (Con A) markedly enhanced the uptake of Staphylococcus aureus H and Escherichia coli 08, respectively. Pretreatment of the respective bacteria with these lectins also greatly increased their uptake by the macroph...

journal_title：Immunology letters

authors： Gallily R,Stain I,Zaady O

更新日期：1986-09-01 00:00:00

abstract：:Psoriasis and psoriatic arthritis (PsA) are common diseases associated with considerable morbidity and disability. Their pathophysiology comprises a dysfunctional stromal-immune cell and cytokine network leading to inflammation of skin, entheses and joints. Recent advances in understanding of disease pathogenesis have...

journal_title：Immunology letters

authors： Hueber AJ,McInnes IB

更新日期：2007-12-15 00:00:00

abstract：:The prevalence of asthma and allergic disease has increased in many countries and there has been speculation that immunization promotes allergic sensitization. Bordetella pertussis infection exacerbates allergic asthmatic responses. We investigated whether whole-cell pertussis vaccine (Pw) enhanced or prevented B. per...

journal_title：Immunology letters

authors： Ennis DP,Cassidy JP,Mahon BP

更新日期：2005-02-15 00:00:00

abstract：:Seroma is a frequent complication of breast cancer surgery, the etiology of which remains indefinite. It represents a subcutaneous accumulation of fluid frequently reported after surgical procedures such as axillary lymph node dissection. Despite previous studies have associated seroma fluid to an inflammatory exudate...

journal_title：Immunology letters

authors： Montalto E,Mangraviti S,Costa G,Carrega P,Morandi B,Pezzino G,Bonaccorsi I,Cancellieri A,Mingari MC,Mesiti M,Ferlazzo G,Melioli G

更新日期：2010-06-15 00:00:00

abstract：:The quasimonoclonal (QM) mouse provides a model to analyze B cell selection because major B cell antigen receptors (BCR) are composed of the knockin V(H)DJ(H) 17.2.25 (V(H)T) encoded H chain and the lambda1 or lambda2 L chain, thereby being specific for (4-hydoxy-3-nitrophenyl)acetyl (NP). We have reported that during...

journal_title：Immunology letters

authors： Kouyama E,Nishikawa Y,Okazawa T,Magari M,Ohmori H,Kanayama N

更新日期：2007-03-15 00:00:00

abstract：:Disease-modifying osteoarthritis (OA) therapy is not yet available. Several adjuvant therapies have demonstrated promising results in the treatment of OA. The present study aimed to investigate the therapeutic effects and underlying mechanisms of a combination of Lactobacillus acidophilus, vitamin B, and curcumin in t...

journal_title：Immunology letters

authors： Jhun J,Min HK,Na HS,Kwon JY,Ryu J,Cho KH,Choi J,Jung K,Lee SY,Kim SJ,Yang CW,Park SH,Cho ML

更新日期：2020-12-01 00:00:00

abstract：:Interleukin-37 (IL-37) has been identified as a novel anti-inflammatory cytokine. The present study aimed to evaluate the expression of IL-37 in serum and in peritoneal fluid to determine its clinical significance in endometriosis. Enzyme-linked immunosorbent assay (ELISA) was performed to examine serum IL-37 levels i...

journal_title：Immunology letters

authors： Kaabachi W,Kacem O,Belhaj R,Hamzaoui A,Hamzaoui K

更新日期：2017-05-01 00:00:00

abstract：:Receptor-binding by the B-subunit of Escherichia coli heat-labile enterotoxin (EtxB) induces apoptosis of peripheral CD8(+), but not CD4(+) T-cells. Given that peripheral CD8(+) and CD4(+) T cells arise from a common developmental pathway in the thymus, we investigated the effects of EtxB on different thymocyte popula...

journal_title：Immunology letters

authors： Salmond RJ,Williams R,Hirst TR,Williams NA

更新日期：2003-07-03 00:00:00

abstract：:Microparticles are recently recognized players of intercellular communication. They are involved in signal transduction, cell activation and apoptosis. Their importance is also suggested in autoimmune diseases such as rheumatoid arthritis and systemic sclerosis. We investigated the role of microparticles in polymyosit...

journal_title：Immunology letters

authors： Baka Z,Senolt L,Vencovsky J,Mann H,Simon PS,Kittel A,Buzás E,Nagy G

更新日期：2010-02-16 00:00:00

abstract：:Many alterations of innate and adaptive immunity are common in the aging population, which reflect a deterioration of the immune system, and have lead to the terms "immune aging" or "immunosenescence". Systems Biology aims to the comprehensive knowledge of the structure, dynamics, control and design that define a give...

journal_title：Immunology letters

authors： O'Connor JE,Herrera G,Martínez-Romero A,de Oyanguren FS,Díaz L,Gomes A,Balaguer S,Callaghan RC

更新日期：2014-11-01 00:00:00

abstract：:While the cytoskeletal protein talin binds to the β-chain of LFA-1, the immune cell adaptor SKAP1 (SKAP-55) binds to the α-chain of the same integrin via RapL. Whereas calpain protease cleavage of talin is important for LFA-1 activation, it has been unclear whether SKAP1 can alter the function of talin or its associat...

journal_title：Immunology letters

authors： Lim D,Lu Y,Rudd CE

更新日期：2016-04-01 00:00:00

abstract：:This report describes an immunoradiometric assay for Plasmodium falciparum in infected blood, based on a cross-reacting monoclonal antibody (mAb) raised against P. berghei. In this assay, binding of the mAb to intact P. berghei parasites coated on microtiter plates is inhibited by solubilized P. falciparum infected re...

journal_title：Immunology letters

authors： Pass A,Avidor B,Golenser J,Laskov R,Sulitzeanu D

更新日期：1985-01-01 00:00:00

abstract：:Graft failure (GF) following bone marrow transplantation (BMT) in man is usually attributed to allograft rejection; however, other mechanisms of GF exist. Exposure of the developing allograft to viruses, myelotoxic drugs, and damage to the host-derived marrow stroma during graft-versus-host disease (GVHD) may all caus...

journal_title：Immunology letters

authors： Hows JM

更新日期：1991-07-01 00:00:00

abstract：:This study tested the hypothesis that the Vδ3 subset of human γδ T cells, like their Vδ2 counterparts, can influence differentiation, antibody secretion and cytokine production by B cells. Vδ3 T cells constitute a minor subset of peripheral blood lymphocytes but are enriched in the liver and gut and are expanded in pa...

journal_title：Immunology letters

authors： Petrasca A,Melo AM,Breen EP,Doherty DG

更新日期：2018-04-01 00:00:00

abstract：:Antibody-dependent and spontaneous lymphocytotoxicity of blood mononuclear cells from 15 patients with chronic renal failure was studied in allogeneic K-562 and xenogeneic chicken erythrocyte test systems. Both antibody-dependent and spontaneous cytotoxic activities were significantly decreased in uremic patients as c...

journal_title：Immunology letters

authors： Láng I,Taraba I,Petrányi G

更新日期：1981-11-01 00:00:00

abstract：:CBA spleen cells have been stimulated in vitro with A/Jap influenza virus-infected CBA spleen cells to generate a 'primary' cytotoxic lymphocyte (CL) response. The culture conditions were devised to allow the segregation of individual clones of CL and cytotoxicity measured by the lysis of infected or non-infected L-92...

journal_title：Immunology letters

authors： Komatsu Y,Nawa Y,Marbrook J

更新日期：1982-01-01 00:00:00

abstract：:At least three B cell subsets, B-1a (Ly-1B), B-1b and B-2, are present in the mouse periphery. B-1a and B1-b cells represent a small population in the adult spleen and are abundant in the peritonial and pleural cavities. It has been demonstrated in our laboratory that B-1b cells spontaneously proliferated in stationar...

journal_title：Immunology letters

authors： Ferreira KS,Almeida SR,Ribeiro CH,Mariano M,Lopes JD

更新日期：2003-03-03 00:00:00

abstract：:Antibody direct cloning from single B cells is simple and efficient and has been successful in antibody identification of infectious diseases. However, although a recent whole-exome sequencing revealed abundant heterogeneic mutation accumulation in cancers, identification and synthesis of autoantibodies against specif...

journal_title：Immunology letters

authors： Iizuka A,Komiyama M,Oshita C,Kume A,Ashizawa T,Mitsuya K,Hayashi N,Nakasu Y,Yamaguchi K,Akiyama Y

更新日期：2014-05-01 00:00:00

abstract：:Neuraminidases act as a virulence factors for several pathogens that invade the human body through Peyer's patch M-cells. Because of the structural similarity of Aleuria aurantia lectin (AAL) to neuraminidases, we hypothesized that AAL might also target human M-cells. In an in vitro human M-cell co-culture model signi...

journal_title：Immunology letters

authors： Roth-Walter F,Bohle B,Schöll I,Untersmayr E,Scheiner O,Boltz-Nitulescu G,Gabor F,Brayden DJ,Jensen-Jarolim E

更新日期：2005-09-15 00:00:00

abstract：:A direct role for delayed hypersensitivity in organized granuloma formation has been emphasized in the literature, but some clinical and experimental studies have suggested a more complicated relationship. In order to further evaluate T-cell function in cutaneous granulomatous inflammation, hepatic granulomas isolated...

journal_title：Immunology letters

authors： Epstein WL,Okamoto M,Suya H,Fukuyama K

更新日期：1986-11-17 00:00:00

abstract：:Pentoxifylline (PTX), a methylxanthine derivative and phosphodiesterase inhibitor, is known to influence production and/or function of some cytokines. We examined the effect of PTX on the in vitro expression of cytokine genes using endotoxin- or phytohaemagglutinin (PHA)-stimulated human blood mononuclear cells. The e...

journal_title：Immunology letters

authors： Rieneck K,Diamant M,Haahr PM,Schönharting M,Bendtzen K

更新日期：1993-08-01 00:00:00

abstract：:The role of the immunomodulator Protein A (PA) (from Staphylococcus aureus, Cowan I strain) in the control of leishmanial infection was studied in experimental animals. Treatment of Leishmania donovani infected hamsters with PA led to a moderate level of reduction of parasite load in their spleen (68%) and liver (46%)...

journal_title：Immunology letters

authors： Ghose AC,Mookerjee A,Sengupta K,Ghosh AK,Dasgupta S,Ray PK

更新日期：1999-02-01 00:00:00

abstract：:Modulation of the IgE response by PHA treatment in relation to animal sex was analysed. Male and female RF mice were immunized with ovalbumin in aluminum hydroxide gel and PHA was injected 1 or 2 days before immunization. Castrated mice were also immunized and received PHA on day -2. The results show that the IgE resp...

journal_title：Immunology letters

authors： Astorquiza MI,Cisternas C,Leal X

更新日期：1987-10-01 00:00:00

abstract：:We have studied the mechanisms involved in the activation or suppression of the immune response by the tumor cells, which is also dependent on the site of tumor transplantation. AK-5 tumor cells when transplanted s.c. activated peritoneal macrophages through the induction of different cytokines, whereas tumor cells wh...

journal_title：Immunology letters

authors： Mitra R,Bhaumik S,Khar A

更新日期：2002-07-03 00:00:00

abstract：:A survey of the appearance of natural antibodies in C57BL/6 mice, measured by a complement-dependent cytotoxicity test against syngeneic radiation leukemia virus-induced lymphoma, was performed. Activity could be detected in sera from 5- to 14-month-old animals. This activity could be attributed mainly to IgM antibodi...

journal_title：Immunology letters

authors： Rubio N

更新日期：1981-10-01 00:00:00

abstract：:ITIM-bearing receptors, a family which only recently has been recognized, play a key role in the regulation of the ITAM-induced activation of immune competent cells. The mechanism of ITM-mediated regulation in various cells was recently clarified. The present review focuses on ITIM bearing membrane proteins that negat...

journal_title：Immunology letters

authors： Gergely J,Pecht I,Sármay G

更新日期：1999-05-03 00:00:00