Abstract:
:In birds, neurons of the isthmo-optic nucleus (ION), as well as "ectopic" neurons, send axons to the retina, where they synapse on cells in the inner nuclear layer (INL). Previous work has shown that centrifugal axons can be divided into two anatomically distinct types depending on their model of termination: either "convergent" or "divergent" (Ramon y Cajal, 1889; Maturana & Frenk, 1965). We show that cytochrome-oxidase histochemistry specifically labels "convergent" centrifugal axons and target neurons which appear to be amacrine cells, as well as three "types" of ganglion cells: two types found in the INL (displaced ganglion cells) and one in the ganglion cell layer. Labeled target amacrine cells have distinct darkly labeled "nests" of boutons enveloping the somas, are associated with labeled centrifugal fibers, and are confined to central retina. Lesions of the isthmo-optic tract abolish the cytochrome-oxidase labeling in the centrifugal axons and in the target amacrine cells but not in the ganglion cells. Cytochrome-oxidase-labeled ganglion cells in the INL are large; one type is oval and similar to the classical displaced ganglion cells of Dogiel, which have been reported to receive centrifugal input; the other type is rounder. Rhodamine beads injected into the accessory optic system results in retrograde label in both types of cells, showing that two distinct types of displaced ganglion cells project to the accessory optic system in chickens. The ganglion cells in the ganglion cell layer that label for cytochrome oxidase also project to the accessory optic system. These have proximal dendrites that ramify in the outer inner plexiform layer.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Nickla DL,Gottlieb MD,Marin G,Rojas X,Britto LR,Wallman Jdoi
10.1017/s0952523800001747subject
Has Abstractpub_date
1994-03-01 00:00:00pages
401-9issue
2eissn
0952-5238issn
1469-8714pii
S0952523800001747journal_volume
11pub_type
杂志文章abstract::To better understand the evolution of spatial and color vision, the number and spatial distributions of cones, rods, and optic nerve axon numbers were assessed in seven New World primates (Cebus apella, Saimiri ustius, Saguinus midas niger, Alouatta caraya, Aotus azarae, Calllithrix jacchus, and Callicebus moloch). Th...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523808080371
更新日期:2008-05-01 00:00:00
abstract::Linking propositions have played an important role in refining our understanding of the relationship between neural activity and perception. Over the last 40 years, visual evoked potentials (VEPs) have been used in many different ways to address questions of the relationship between neural activity and perception. Thi...
journal_title:Visual neuroscience
pub_type: 杂志文章,评审
doi:10.1017/S0952523813000205
更新日期:2013-11-01 00:00:00
abstract::Ganglion cells of the cat retina that are neither alpha nor beta cells are often lumped for convenience into a single anatomical group--the gamma cells (Boycott & Wässle, 1974; Stone, 1983; Wässle & Boycott, 1991). Defined in this way, gamma cells are the morphological counterpart to the physiological W-cell class, wh...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380000897x
更新日期:1995-07-01 00:00:00
abstract::The effects of dopamine on luminosity-type horizontal cells have been documented in different vertebrate retinas, both in vivo and in vitro. Some of these effects may reflect direct action of dopamine onto these cells, but indirect effects mediated by presynaptic neurons cannot be ruled out. Furthermore, direct effect...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008312
更新日期:1995-05-01 00:00:00
abstract::The large receptive fields of retinal horizontal cells are thought to reflect extensive electrical coupling via gap junctions. It was shown recently that the biotinylated tracers, biocytin and Neurobiotin, provide remarkable images of coupling between many types of retinal neuron, including horizontal cells. Further, ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800009524
更新日期:1995-09-01 00:00:00
abstract::To examine the role of visual area V4 in pattern vision, we tested two monkeys with lesions of V4 on tasks that required them to discriminate the orientation of contours defined by several different cues. The cues used to separate the contours from their background included luminance, color, motion, and texture, as we...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008208
更新日期:1996-05-01 00:00:00
abstract::We tested the hypothesis that gamma-aminobutyric acid (GABA) is the transmitter released by barnacle photoreceptors onto postsynaptic cells (I-cells). GABA was applied to I-cells either by superfusion or by ejecting it with pressure from a pipette positioned close to the I-cell's soma. The I-cell's response to GABA wa...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800005496
更新日期:1989-10-01 00:00:00
abstract::The development of spatial vision is relatively well documented in human and nonhuman primates. However, little is known about the development of sensitivity to motion. We measured the development of sensitivity to direction of motion, and the relationship between motion and contrast sensitivity in macaque monkeys as ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523804216054
更新日期:2004-11-01 00:00:00
abstract::Monocular deprivation (MD) by lid suture is one of the classic paradigms for the study of developmental plasticity in the cerebral cortex, and we have detailed knowledge of its anatomical and physiological consequences as well as underlying molecular and cellular mechanisms. However, the effects of other forms of mani...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523812000260
更新日期:2012-09-01 00:00:00
abstract::The dopamine (DA) innervation, labeled by tyrosine hydroxylase immunohistochemistry in a wholemounted human retina, is described in the avascular area of the fovea. Eleven DA neurons give rise to this innervation, among which five are interplexiform cells, so that the DA innervation consists of two plexuses: one is in...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800009779
更新日期:1991-11-01 00:00:00
abstract::The purpose of the present study was to examine the contributions made by cat posterior parietal cortex to the analyses of the relative position of objects in visual space. Two cats were trained on a landmark task in which they learned to report the position of a landmark object relative to a right or left food-reward...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800175042
更新日期:2000-09-01 00:00:00
abstract::Human, macaque monkey, and rat retinas were immunostained with a polyclonal antibody preparation against purified recoverin, a 23-kD calcium-binding protein isolated from bovine retina that localizes to rods and cones (Dizhoor et al., 1991). In addition to immunoreactive photoreceptors, we have identified subpopulatio...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800003175
更新日期:1993-01-01 00:00:00
abstract::Color vision impairment was examined in patients with type 2 diabetes mellitus (DM2) without retinopathy. We assessed the type and degree of distortions of individual color spaces. DM2 patients (n = 32), and age-matched controls (n = 20) were tested using the Farnsworth D-15 and the Lanthony D-15d tests. In addition, ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806233546
更新日期:2006-05-01 00:00:00
abstract::In binocular vision, the lateral displacement of the eyes gives rise to both horizontal and vertical disparities between the images projected onto the left and right retinae. While it is well known that horizontal disparity is exploited by the binocular visual system of birds and mammals to enable depth perception, th...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s095252380118404x
更新日期:2001-07-01 00:00:00
abstract::R1-6 dominated electroretinographic (ERG) spectral sensitivities were determined as a function of days posteclosion from carotenoid deprived and replaced white-eyed Drosophila. The sensitivity of flies deprived from egg to adult waxed (about 1.5 log units by day 3), and then waned gradually from 3-11 days (over 2 log ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800011263
更新日期:1992-11-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800007756
更新日期:1996-11-01 00:00:00
abstract::This study of the tree shrew, Tupaia belangeri, provides evidence for an intracollicular pathway that arises in the superficial gray layer and terminates in the optic layer. As a first step, Nissl, myelin, and cytochrome oxidase stains were used to identify the layers of the superior colliculus in the tree shrew. Seco...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008464
更新日期:1995-05-01 00:00:00
abstract::We have developed two brain slice preparations for studying tectofugal visual pathways in the chick: conventional, 400-microns slices ("thin slices"), and "thick slices" which encompass the rostral pole of the optic tectum and the contralateral optic nerve. Stimulation was delivered with a bipolar electrode positioned...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800008622
更新日期:1996-07-01 00:00:00
abstract::The topographical distributions of the relative ratio of long- (L) and middle- (M) wavelength sensitive cone opsin messenger RNA (mRNA) in human and baboon retinas were mapped using real-time polymerase chain reaction. The L:M mRNA ratio increased in a central-to-peripheral gradient in both species, being quite pronou...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S095252380623325X
更新日期:2006-05-01 00:00:00
abstract::White noise stimuli were used to estimate second-order kernels for complex cells in cortical area V1 of the macaque monkey, and drifting grating stimuli were presented to the sample of neurons to obtain orientation and spatial-frequency tuning curves. Using these data, we quantified how well second-order kernels predi...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800003102
更新日期:1994-07-01 00:00:00
abstract::Early in life, visual experience appears to influence the refinement and maintenance of the orientation-selective responses of neurons in the primary visual cortex. After eye opening, the statistical structure of visually driven neural responses depends not only on the stimulus, but also on how the stimulus is scanned...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523804215073
更新日期:2004-09-01 00:00:00
abstract::Neighboring retinal ganglion cells often spike synchronously, but the possible function and mechanism of this synchrony is unclear. Recently, the strength of the fast correlation between ON-OFF directionally selective cells of the rabbit retina was shown to be stimulus dependent. Here, we extend that study, investigat...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523807070757
更新日期:2007-11-01 00:00:00
abstract::The eye has become an excellent target for gene therapy, and gene augmentation therapy of inherited retinal disorders has made major progress in recent years. Nevertheless, a recent study indicated that gene augmentation intervention might not stop the progression of retinal degeneration in patients. In addition, for ...
journal_title:Visual neuroscience
pub_type: 杂志文章,评审
doi:10.1017/S0952523814000194
更新日期:2014-09-01 00:00:00
abstract::The size, pattern of terminal arborizations, and laminar specificity of individual retinogeniculate axons were studied in the macaque following injections of HRP into the optic tract. Axons that terminated in the magnocellular layers had significantly larger fiber diameters and wider terminal fields than those that te...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800001206
更新日期:1989-01-01 00:00:00
abstract::In previous work, we have shown that sudden image displacements well outside the classical receptive field modulate the visual sensitivity of LGN relay cells. Here we report the effect of image displacements on the response versus contrast function. The stimuli consisted of a central spot of optimal size and polarity ...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523899165143
更新日期:1999-09-01 00:00:00
abstract::Many cell types in the retina are coupled via gap junctions and so there is a pressing need for a potent and reversible gap junction antagonist. We screened a series of potential gap junction antagonists by evaluating their effects on dye coupling in the network of A-type horizontal cells. We evaluated the following c...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523807070472
更新日期:2007-07-01 00:00:00
abstract::Recent interest in nitric oxide and its relationship to cGMP has produced many attempts to anatomically localize the enzyme synthesizing nitric oxide, nitric oxide synthase. In the retina, numerous previous studies have used the NADPH-diaphorase enzyme activity of nitric oxide synthase as a histochemical method to loc...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800012670
更新日期:1997-07-01 00:00:00
abstract::During early mammalian development, inputs from the two retinas intermix within the lateral geniculate nucleus (LGN), then segregate during the first postnatal week into layers that receive input from a single retina. Functionally, the LGN also changes markedly during the first postnatal month; early geniculate respon...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523899163107
更新日期:1999-05-01 00:00:00
abstract::Wide-field cone bipolar cells with sparse dendritic branching and proposed connectivity to blue cones were first identified in rabbit and cat. In rabbit, these were subdivided into type a (wa) and type b (wb), with axonal branching in sublamina a, and sublamina b, respectively, of the inner plexiform layer (IPL). Rece...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523808080061
更新日期:2008-01-01 00:00:00
abstract::A series of psychophysical tests examining early and later aspects of image-motion processing were conducted in a patient with bilateral lesions involving the posterior visual pathways, affecting the lateral parietal-temporal-occipital cortex and the underlying white matter (as shown by magnetic resonance imaging stud...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/s0952523800000444
更新日期:1990-10-01 00:00:00