Current status of Duchenne muscular dystrophy.

Abstract:

:Duchenne muscular dystrophy is the second most common lethal genetic disorder in humans. With the advent of molecular genetic technology, the definition of this disease has been modified to include an abnormality of dystrophin in muscle--a dystrophinopathy. Accurate genetic counseling is possible using methods of deletion detection and linkage analysis. Treatment of this type of muscular dystrophy may soon mean the routine use of steroids and later include direct injection of an artificial gene for dystrophin.

journal_name

Pediatr Clin North Am

authors

Iannaccone ST

doi

10.1016/s0031-3955(16)38379-1

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

879-94

issue

4

eissn

0031-3955

issn

1557-8240

pii

S0031-3955(16)38379-1

journal_volume

39

pub_type

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