Cerebral responses to acute maternal alcohol intoxication in immature fetal sheep.

abstract：:We examined 78 fetuses on d 21 of gestation (G21) and 83 neonates on d 2 after birth (A2), which were first generation offspring of WKY rats mated with normal Wistar rats (F1). In addition, we examined six groups of fetuses on d 19 of gestation (G19): 65 Wistar rats, 111 WKY rats, 85 F1, 100 F1 X F1, 92 F1 X Wistar, a...

journal_title：Pediatric research

authors： Kuribayashi T,Taniwaki M,Nakamichi K,Nakamura T,Shimoo K,Nakagawa M,Nagaoka A,Komeda T,Ibata Y

更新日期：1991-09-01 00:00:00

abstract：:Bilirubin-IX alpha photooxidation products were detected by high performance liquid chromatography in the urine of neonates undergoing phototherapy for hyperbilirubinemia. The in vivo photoproducts were identified by chromatographic comparison with authentic synthetic standards using two complementary methods. Bilirub...

journal_title：Pediatric research

authors： Lightner DA,Linnane WP 3rd,Ahlfors CE

更新日期：1984-08-01 00:00:00

abstract：:The influence of maternal stress during pregnancy on the postpartum iron status and immune maturation of infants was investigated in a nonhuman primate model. Forty infant rhesus monkeys were generated from two types of disturbed pregnancies, early or late gestation stress, and compared with 24 undisturbed controls. P...

journal_title：Pediatric research

authors： Coe CL,Lubach GR,Shirtcliff EA

更新日期：2007-05-01 00:00:00

abstract：:Biochemical analysis and morphologic observation of the iliac crest cartilage from 8-year-old girl with I-cell disease were performed. Instead of hypertrophic change of chondrocytes in the zone of cartilage-bone junction, there were small atrophic cells having many inclusion bodies accumulated with lamellar materials....

journal_title：Pediatric research

authors： Nogami H,Oohira A,Suzuki F,Tsuda K

更新日期：1981-04-01 00:00:00

abstract：:Tonsillectomy and adenoidectomy (T&A) is a frequent surgical procedure in children with obstructive sleep apnea (OSA). Many symptomatic children who do not fulfill the currently recommended criteria for T&A may benefit from topical intranasal steroid therapy. However, the expression of glucocorticoid receptor (GCR) ex...

journal_title：Pediatric research

authors： Goldbart AD,Veling MC,Goldman JL,Li RC,Brittian KR,Gozal D

更新日期：2005-02-01 00:00:00

abstract：:In blood vessels with diameters less than 500 microns, both the hematocrit and viscosity decrease with decreasing tube diameter [Fåhraeus effect (FE) and Fåhraeus-Lindqvist effect (FLE)]. Because both effects may be influenced by red blood cell (RBC) volume and osmolality, the effects of RBC type and suspending medium...

journal_title：Pediatric research

authors： McKay CB,Linderkamp O,Meiselman HJ

更新日期：1993-10-01 00:00:00

abstract：:Pediatric research may be entering a period of failure to thrive. This is despite impressive scientific achievements, significant financial benefits, intriguing unanswered questions and a rewarding life for the pediatric researcher. Many of the difficulties are financial and situational, including small departments an...

journal_title：Pediatric research

authors： Stiehm ER

更新日期：1985-06-01 00:00:00

abstract：INTRODUCTION:Data regarding neonatal arterial ischemic stroke (NAIS) topography are still sparse and inaccurate. Despite the importance of locating NAIS to predict the long-term outcome of neonates, a map of arterial territories is not yet available. Our aim was therefore to generate the first three-dimensional map of ...

journal_title：Pediatric research

authors： Núñez C,Arca G,Agut T,Stephan-Otto C,García-Alix A

更新日期：2020-06-01 00:00:00

abstract：:To determine the developmental changes in the myocardial current during fetal life, and to evaluate the clinical usefulness of magnetocardiography for prenatal diagnosis of cardiac hypertrophy or enlargement, we approximated the magnitude of the one-current dipole of the fetal heart using fetal magnetocardiography (fM...

journal_title：Pediatric research

authors： Horigome H,Shiono J,Shigemitsu S,Asaka M,Matsui A,Kandori A,Miyashita T,Tsukada K

更新日期：2001-08-01 00:00:00

abstract：:Genetic typing of serum transferrin was performed in a group of 88 extremely premature infants (gestation age less than 32 wk) and in a control group of 351 full-term infants, using isoelectric focusing technique on ultrathin layer of polyacrilamide gel. A major incidence of C2 type was found among the preterm infants...

journal_title：Pediatric research

authors： Auconi P,Biagini R,Colarizi P,Pascali V

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Newborn pigs offer theoretical advantages for studying newborn hypoxic-ischemic (HI) brain damage because of a development and structure similar to the human brain. However, the correlation between functional features and actual HI brain damage has not been reported. METHODS:Newborn pigs were examined daily...

journal_title：Pediatric research

authors： Barata L,Cabañas A,Lafuente H,Vargas C,Ceprián M,Campa L,Jiménez-Sánchez L,Pazos MR,Alvarez FJ,Martínez-Orgado J

更新日期：2019-03-01 00:00:00

abstract：:Lung distensibility and airway mechanics were evaluated in 24 asthmatic children and adolescents, ages between 7 and 21 years, by quasi-static pressure-volume curves and by the static recoil-lung conductance relationship. The measurements were obtained by the step-wise inflation technique and the pressure-volume curve...

journal_title：Pediatric research

authors： Kraemer R,Geubelle F

更新日期：1984-11-01 00:00:00

abstract：:Bubble continuous positive airway pressure (B-CPAP) applies small-amplitude, high-frequency oscillations in airway pressure (DeltaPaw) that may improve gas exchange in infants with respiratory disease. We developed a device, high-amplitude B-CPAP (HAB-CPAP), which provides greater DeltaPaw than B-CPAP provides. We stu...

journal_title：Pediatric research

authors： Diblasi RM,Zignego JC,Tang DM,Hildebrandt J,Smith CV,Hansen TN,Richardson CP

更新日期：2010-06-01 00:00:00

abstract：:Although the use of antenatal glucocorticoids has resulted in decreased neonatal morbidity/mortality, recent animal studies have raised concerns regarding adverse effects of these medications on postnatal cardiovascular function. We hypothesized that antenatal betamethasone (Beta) exposure alters cerebral vascular rea...

journal_title：Pediatric research

authors： Eckman DM,Kerr BA,Fuloria M,Simandle SA,Watt SE,Rose JC,Figueroa JP

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Long-term prefrontal cortex (PFC)- and hippocampus-based cognitive deficits are the sequelae of perinatal iron deficiency, despite iron supplementation starting in the newborn period. Whether high-dose iron supplementation prevents these deficits is yet to be determined. METHODS:Perinatal iron deficiency wa...

journal_title：Pediatric research

authors： Rao R,Tkac I,Unger EL,Ennis K,Hurst A,Schallert T,Connor J,Felt B,Georgieff MK

更新日期：2013-01-01 00:00:00

abstract：:Preterm infants are exposed to frequent painful procedures and agitating stimuli over the many weeks of their hospitalization in the neonatal intensive care unit (NICU). The adverse neurobiological impact of pain and stress in the preterm infant has been well documented, including neuroimaging and neurobehavioral outc...

journal_title：Pediatric research

authors： McPherson C,Miller SP,El-Dib M,Massaro AN,Inder TE

更新日期：2020-08-01 00:00:00

abstract：:We evaluated the hypothesis that increased endogenous opioid activity mediates part or all of the left ventricular contractile and pump dysfunction previously demonstrated in HCl-induced metabolic acidemia. Eighteen Western newborn lambs were catheterized and instrumented; pacing wires were sutured to the right atrial...

journal_title：Pediatric research

authors： Fisher DJ,Dreyer WJ,Tate C,Michael L,Smith EO,Entman M

更新日期：1988-06-01 00:00:00

abstract：:The intranasal live attenuated influenza vaccine (LAIV), FluMist, has been widely appreciated by pediatricians, parents, and children alike for its ease of administration. However, concerns regarding lack of effectiveness in recent influenza seasons led to the CDC Advisory Committee on Immunization Practices (ACIP) re...

journal_title：Pediatric research

authors： Gill MA,Schlaudecker EP

更新日期：2018-01-01 00:00:00

abstract：:Sodium deficiency is associated with decreased muscle growth and protein synthesis. We investigated the influence of diet-induced sodium deficiency on the rate and extent of compensatory growth of the right lung after left pneumonectomy in young rats of 83 +/- 1 g body weight. Starting 1 wk before surgery, all rats we...

journal_title：Pediatric research

authors： Gallaher KJ,Wolpert E,Wassner S,Rannels DE

更新日期：1990-11-01 00:00:00

abstract：:Previous studies have shown that proton magnetic resonance spectroscopy (MRS) is useful in predicting neurologic prognosis in children with traumatic brain injury (TBI). Reductions in N-acetyl derived metabolites and presence of lactate have been predictive of poor outcomes. We examined another spectroscopy metabolite...

journal_title：Pediatric research

authors： Ashwal S,Holshouser B,Tong K,Serna T,Osterdock R,Gross M,Kido D

更新日期：2004-10-01 00:00:00

abstract：:To determine the effects of age, feeding regimen, and antenatal glucocorticoids on intestinal permeability, preterm infants (n = 132) were stratified by gestational age and by diet (mothers' own milk versus preterm formula), and assigned randomly to one of four feeding regimens: early-continuous, early-bolus, standard...

journal_title：Pediatric research

authors： Shulman RJ,Schanler RJ,Lau C,Heitkemper M,Ou CN,Smith EO

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Biliary atresia (BA) is an infantile disorder characterized by progressive sclerosing cholangiopathy leading to biliary obstruction. First-line treatment of BA is hepatoportoenterostomy, the prognosis of which is related to age at surgery and to histological variables such as extent of fibrosis and ductular ...

journal_title：Pediatric research

authors： de Souza AF,Meurer L,da Silveira TR,Gregório C,Reus N,Uribe C,Matte U,dos Santos JL

更新日期：2014-01-01 00:00:00

abstract：:A son of related Turkish parents had grossly elevated serum tyrosine concentration and excreted tyrosine and p-hydroxyphenolic acids into the urine, whereas neither succinylacetone nor succinylacetoacetate could be demonstrated. The tyrosine concentration was normalized by a proper diet. This was not followed strictly...

journal_title：Pediatric research

authors： Andersson S,Nemeth A,Ohisalo J,Strandvik B

更新日期：1984-07-01 00:00:00

abstract：:To determine the pathophysiologic significance of pertussis toxin (PT) on the human beta-adrenergic system, beta-adrenoceptor (beta-R)-density and cyclic AMP response of peripheral mononuclear blood cells (MN leukocytes) were studied in children during the paroxysmal stage of natural pertussis infection, after vaccina...

journal_title：Pediatric research

authors： Griese M,Sideropoulou O,Reinhardt D

更新日期：1989-02-01 00:00:00

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：:The purpose of the study was to investigate the effect of low doses of dopamine in children. Fourteen cases were studied after open heart surgery. Cardiac output and renal parameters were determined under baseline conditions and under continuous infusion of dopamine 2.5 and 5 micrograms/kg/min. During the control peri...

journal_title：Pediatric research

authors： Girardin E,Berner M,Rouge JC,Rivest RW,Friedli B,Paunier L

更新日期：1989-09-01 00:00:00

abstract：:Atherosclerosis originates in childhood and adolescence. The goal of this review is to highlight how exercise and physical activity during childhood and adolescence, critical periods of growth and development, can prevent adult cardiovascular disease (CVD), particularly through molecular mechanisms of monocytes, a key...

journal_title：Pediatric research

authors： Cooper DM,Radom-Aizik S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Fetal hypoxia-ischemia (H-I) results in significant morbidity and mortality. Little is known about the timing of death in human stillbirths. The vulnerability of the fetus varies with age at the time of insult, but it is unknown what happens to the timing of fetal death in relation to a fetal insult. We aske...

journal_title：Pediatric research

authors： Derrick M,Englof I,Drobyshevsky A,Luo K,Yu L,Tan S

更新日期：2012-08-01 00:00:00

abstract：:Prenatal exposure to infection and subsequent inflammatory responses have been implicated in the etiology of schizophrenia and autism. In this review, we summarize current evidence from human and animal studies supporting the hypothesis that the pathogenesis of these two disorders is linked via exposure to inflammatio...

journal_title：Pediatric research

authors： Meyer U,Feldon J,Dammann O

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:The epithelial-mesenchymal transition (EMT) has been implicated as a key mechanism in the pathogenesis of liver fibrosis. The miR-200 family has been shown to inhibit EMT. METHODS:Liver fibrosis levels were assessed with Masson's trichrome staining of liver samples obtained from biliary atresia (BA) patient...

journal_title：Pediatric research

authors： Xiao Y,Zhou Y,Chen Y,Zhou K,Wen J,Wang Y,Wang J,Cai W

更新日期：2015-02-01 00:00:00