Abstract:
UNLABELLED:Pregnancy is a hypercoagulable state that increases the risk of thromboembolic events. These risks may be further increased in the presence of an acquired or inherited thrombophilia. Thrombophilias have been associated with both maternal and fetal complications. The use of anticoagulants during pregnancy may reduce the risk of maternal thromboses as well as the risk of adverse pregnancy outcomes. The choice of an anticoagulant requires consideration of maternal risks, potential for teratogenicity, the underlying condition necessitating the treatment, and cost. This review examines the options for anticoagulation, the clinical situations that may warrant such treatment, and factors to be considered at delivery and during the postpartum period. TARGET AUDIENCE:Obstetricians & Gynecologists, Family Physicians. LEARNING OBJECTIVES:After completion of this article, the reader should be able to describe the roles of acquired and inherited thrombophilia in furthering the hypercoagulable state of pregnancy, identify the potential consequences of using anticoagulants during pregnancy, and summarize the treatment options when anticoagulation is required during pregnancy.
journal_name
Obstet Gynecol Survjournal_title
Obstetrical & gynecological surveyauthors
James AH,Abel DE,Brancazio LRdoi
10.1097/01.ogx.0000193878.57208.adsubject
Has Abstractpub_date
2006-01-01 00:00:00pages
59-69; quiz 70-72issue
1eissn
0029-7828issn
1533-9866pii
0006254-200601000-00026journal_volume
61pub_type
杂志文章,评审abstract:UNLABELLED:Whether practice differences exist between the sexes is a question of clinical and educational significance. The obstetrician-gynecologist (ob-gyn) workforce has been shifting to majority women. An examination of sex differences in ob-gyn practice contributes to the discussion about how the changing workforc...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e318286f0aa
更新日期:2013-03-01 00:00:00
abstract:Importance:Despite increasing attention to the importance of father involvement during pregnancy, the literature on fathers' roles in perinatal decision making is scant. Objective:The aim of this study was to conduct a narrative review of the literature exploring fathers' preferences, perspectives, and involvement in ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
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更新日期:2019-03-01 00:00:00
abstract:Importance:Postpartum hemorrhage (PPH) remains a major cause of maternal mortality worldwide, occurring in both vaginal and cesarean deliveries. We have witnessed improvements in both prevention and treatment of PPH. Tranexamic acid (TXA) has been investigated as a potential adjunct therapy to uterotonics within this s...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000597
更新日期:2018-10-01 00:00:00
abstract::Trichomonas vaginalis (TV) is the most common curable sexually transmitted infection worldwide. Annually, 7.4 million new infections are estimated in the United States, which is greater than combined new cases of Chlamydia, gonorrhea, and syphilis. Serious adverse reproductive health outcomes including pregnancy compl...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e318279fb7d
更新日期:2013-01-01 00:00:00
abstract::A patient with a hydatidiform mole complicated by eclampsia is presented. The findings from 57 other cases discovered in a review of the literature since 1866 are summarized to define the clinical characteristics of women experiencing eclampsia as a manifestation of their hydatidiform mole. Eclampsia complicating a mo...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:
更新日期:1988-04-01 00:00:00
abstract:Importance:Vaginal birth after previous cesarean birth (VBAC) is a reasonable option for many women with previous cesarean delivery. Objective:The aim of this study was to summarize evidence and compare recommendations from national guidelines regarding VBAC. Evidence Acquisition:A descriptive review of 3 national gu...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章
doi:10.1097/OGX.0000000000000596
更新日期:2018-09-01 00:00:00
abstract::Quinolones and fluoroquinolones are highly efficient antibiotics. However, concerns regarding possible harmful effects have limited their use during pregnancy. Nevertheless, accumulating clinical data suggest that they may be safe during pregnancy. This review aimed to explore the mechanisms of action of the quinolone...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000122
更新日期:2014-11-01 00:00:00
abstract::The assessment of osteoporosis risk factors can help guide early intervention. The objective of this study was to analyze numerous potential risk factors to see which were associated with postmenopausal osteoporosis. Women aged 49 or greater presenting for dual-energy x-ray absorptiometry bone scans were recruited fro...
journal_title:Obstetrical & gynecological survey
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doi:10.1097/OGX.0b013e3181fc6d30
更新日期:2010-09-01 00:00:00
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journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000613
更新日期:2018-11-01 00:00:00
abstract::Arthropod-borne bacterial diseases affect more than 25,000 Americans every year and thousands more around the world. These infections present a diagnostic dilemma for clinicians because they mimic many other pathologic conditions and are often low on or absent from the differential diagnosis list. Diagnosis is particu...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3182a5ed46
更新日期:2013-09-01 00:00:00
abstract:UNLABELLED:Thromboembolism in pregnancy is a major contributor to pregnancy morbidity and mortality with potentially serious adverse effects for both mother and fetus. The purposes of this article are to explore the impact of heritable and acquired thrombophilias on pregnancy and to determine the appropriateness of scr...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000165116.96026.4e
更新日期:2005-06-01 00:00:00
abstract::Anesthesia and surgery interfere with normal thermoregulation, and nearly all patients will become hypothermic unless compensatory measures are used. Preoperative patient warming and intraoperative methods using forced air and warmed intravenous fluids are important methods for maintaining patient's core temperature d...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3182605ccd
更新日期:2012-07-01 00:00:00
abstract::Recent advances in the field of reproduction have made it possible to obtain preembryos and to use them in many research applications. These include research into improving methods of IVF treatment, contraceptive research, preimplantation diagnosis, gene therapy, the study of malignant disease, and others. The benefit...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199709000-00022
更新日期:1997-09-01 00:00:00
abstract::HIV infection has been associated with progressive deterioration of the immune system and the development of opportunistic infections and various malignancies. As more experience has been accumulated on the nature and complications of AIDS, the gynecological implications of neoplasia developing in the HIV-positive pat...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199611000-00022
更新日期:1996-11-01 00:00:00
abstract:UNLABELLED:Depression is common in reproductive age women, and continued pharmacologic treatment of depression during pregnancy may be necessary to prevent relapse, which could be harmful for both the fetus and the mother. Although data on drug safety are imperfect and incomplete, the benefits of antidepressant therapy...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181676be8
更新日期:2008-04-01 00:00:00
abstract:UNLABELLED:To assess the impact of dengue infection during pregnancy on birth outcomes, we conducted a systematic review of 30 published studies (19 case reports, 9 case series, and 2 comparison studies). Studies were identified by searching computerized databases using dengue and dengue hemorrhagic fever, cross-refere...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181cb8fbc
更新日期:2010-02-01 00:00:00
abstract:UNLABELLED:Primary pure ovarian leiomyosarcomas constitute a malignant subgroup of ovarian smooth muscle tumors which comprise only 1% of ovarian tumors. Their origin, etiology, histologic features, clinical behavior, and optimal treatment are still obscure. Malignant behavior is almost always associated with any 2 of ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/01.ogx.0000268629.16151.71
更新日期:2007-07-01 00:00:00
abstract:Importance:Real-time electrohysterography (EHG)-based technologies have recently become available for uterine monitoring during term labor. Therefore, obstetricians need to be familiar with the diagnostic value, advantages, and limitations of using EHG. Objective:The aims of this study were to determine the diagnostic...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
abstract:PROBLEM:Preterm birth (PTB) is an oxidative stress-related disease that lacks effective therapies partly because of the poor understanding of disease pathogenesis. The aim of this manuscript was to review molecular pathways that could be responsible for the pathogenesis of PTB. Genomic and proteomic studies have starte...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e318181a79f
更新日期:2008-10-01 00:00:00
abstract::The use of blood products has come under closer scrutiny over the past decade because of the autoimmune deficiency syndrome. Newer technology has led to the use of component therapy in most situations. The use of fresh-frozen plasma has been overstated in the older literature, and fresh-frozen plasma should be used in...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199105000-00015
更新日期:1991-05-01 00:00:00
abstract:Importance:Hereditary angioedema (HAE) is a rare but severe disease, with high risk of death, and attacks have been associated to high estrogen levels. Polycystic ovary syndrome (PCOS) is a common hyperandrogenic condition, which is frequently treated with combined oral contraceptives. Objective:The aim of this study ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000457
更新日期:2017-07-01 00:00:00
abstract::This review first makes some general comments about prophylactic antibiotics: animal models for antimicrobial prophylaxis, bacterial flora of the female genital tract, timing and duration of prophylactic antibiotic administration, and drug of choice for prophylaxis. Subsequent sections cover the following: prophyla...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-198409000-00001
更新日期:1984-09-01 00:00:00
abstract::A variegated group of autoimmune disorders tend to occur in women during childbearing years. Autoantibodies, often of IgG type, directed against the mother's (self) antigens has been well characterized in a number of these disorders. Transplacental transfer of IgG autoantibodies has been frequently demonstrated withou...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:
更新日期:1991-11-01 00:00:00
abstract:UNLABELLED:Human reproduction provides unique opportunities for the transmission of infectious agents. Furthermore, the mother and her offspring have distinct susceptibilities to infection at each stage of reproduction, from conception and gestation to parturition and the neonatal period. The impact of pathogens on rep...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e3181c9e7a1
更新日期:2010-01-01 00:00:00
abstract::Fibromatosis is a benign, infiltrating, nonmetastasizing neoplasm which is rarely completely resected. Therefore, the incidence of recurrence is high. Fibromatosis is more common in females and is frequently diagnosed during pregnancy. Inasmuch as fibromatosis of the female pelvis appears to be a discrete entity, mana...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-198905000-00012
更新日期:1989-05-01 00:00:00
abstract:Importance:Globally, more than 125 million women each year are at risk of malaria during pregnancy. Endemic regions carry the greatest burden; however, with globalization, providers in nonendemic regions are encountering increasing numbers of women exposed to or infected with malaria. Objectives:The aim of this articl...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0000000000000704
更新日期:2019-09-01 00:00:00
abstract:UNLABELLED:Intracytoplasmic sperm injection, a relatively new technique used at the time of in vitro fertilization to fertilize human oocytes, has provided couples with very severe male factor infertility the ability to conceive their own biologic children. Many men with severe oligospermia or azoospermia can now pass ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章
doi:10.1097/00006254-200001000-00024
更新日期:2000-01-01 00:00:00
abstract::Pregnancy complicated by a thermal injury must be aggressively managed to provide a favorable outcome for the mother and her developing fetus. The MEDLINE database was used to search for English-language papers published after 1980 to evaluate the classification, complications, and treatment of thermal injuries in pre...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/00006254-199801000-00024
更新日期:1998-01-01 00:00:00
abstract::The last three decades have witnessed a dramatic increase in the use of assisted reproductive technology (ART) so that now, in developed countries, 1.7% to 4.0% of all children are born after ART. Although absolute risks appear small, data from prospective and retrospective studies indicate increased risks of adverse ...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章,评审
doi:10.1097/OGX.0b013e31826a5d4a
更新日期:2012-09-01 00:00:00
abstract:Importance:Women with a history of preeclampsia have a 2- to 5-fold increased risk of cardiovascular diseases, which represent almost half of mortality in the female population worldwide. Objective:To summarize the current evidence concerning women's future cardiovascular risk after pregnancies complicated by preeclam...
journal_title:Obstetrical & gynecological survey
pub_type: 杂志文章
doi:10.1097/OGX.0000000000000846
更新日期:2020-11-01 00:00:00