当前位置： SCI文献检索 > UROLOGY期刊下所有文献 > Frequency and clinicopathologic correlates of ErbB1, ErbB2, and ErbB3 immunoreactivity in urothelial tumors of upper urinary tract.

Frequency and clinicopathologic correlates of ErbB1, ErbB2, and ErbB3 immunoreactivity in urothelial tumors of upper urinary tract.

Abstract：

OBJECTIVES:To investigate the frequency and clinicopathologic correlates of ErbB1, ErbB2, and ErbB3 receptor expression in patients with upper urothelial carcinoma. METHODS:Immunohistochemical staining for ErbB1, ErbB2, and ErbB3 was done with serial sections from archival specimens of 94 patients who underwent nephroureterectomy plus bladder cuff resection for urothelial carcinoma of the renal pelvis and ureter (median follow-up 40 months, range 1 to 177). The correlates between ErbB receptor expression and clinical outcome in terms of recurrence, progression, disease-free survival, and overall survival were analyzed by Kaplan-Meier plots, with the log-rank test and Cox proportional hazards model. RESULTS:ErbB1, ErbB2, and ErbB3 expression was present in 9 (9.5%), 13 (13.8%), and 26 (27.7%) tumors, respectively. Thirty-seven patients (39.4 %) had at least one receptor expressed and eight (8.5%) had coexpression of two or three receptors. ErbB2 expression was significantly associated with tumor invasiveness (P = 0.03), and ErbB1 and ErbB3 expression was not. The incidence of subsequent tumor recurrence in the urinary bladder correlated significantly with ureteral tumor involvement and ErbB2 expression (P = 0.04 and P = 0.04, respectively). On univariate and multivariate analyses, tumor staging and ErbB2 expression were independent predictors of disease progression (P = 0.01 and P = 0.01, respectively), disease-free survival (P = 0.02 and P = 0.002, respectively), and overall survival (P = 0.01 and P = 0.02, respectively). CONCLUSIONS:ErbB2 expression predicts for disease progression and disease-related survival in upper urothelial carcinoma.

journal_name

Urology

journal_title

Urology

authors

Tsai YS,Tzai TS,Chow NH,Wu CL

doi

10.1016/j.urology.2005.06.117

subject

Has Abstract

pub_date

2005-12-01 00:00:00

pages

1197-202

issue

6

eissn

0090-4295

issn

1527-9995

pii

S0090-4295(05)00926-X

journal_volume

66

pub_type

杂志文章

相关文献

UROLOGY文献大全
  • Robot-assisted Partial Nephrectomy: Is Routine Urinary Catheterization Still Mandatory in the Era of Enhanced Recovery?

    abstract：OBJECTIVE:To assess the benefits and safety of noncatheterization during robot-assisted partial nephrectomy within an enhanced recovery protocol. MATERIALS AND METHODS:A single-center retrospective comparative study was carried out of consecutive patients who underwent a robot-assisted partial nephrectomy between Febr...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2018.09.028

    authors： Tremblais B,Dominique I,Terrier JE,Ecochard R,Hacquard H,Ruffion A,Paparel P

    更新日期：2019-02-01 00:00:00

  • Leydig cell tumor of intra-abdominal testis.

    abstract：:A patient with bilateral cryptorchidism and gynecomastia due to Leydig cell tumor involving the left intra-abdominal testis is described. Raised serum estrogen, low serum testosterone, and ultrasonic demonstration of a tumor in the left testis allowed the diagnosis to be suspected preoperatively. The relevant literatu...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(93)90546-m

    authors： Allen FJ,Van Vollenhoven F

    更新日期：1993-12-01 00:00:00

  • Urinary symptoms associated with human T-cell lymphotropic virus type I infection: evidence of urinary manifestations in large group of HTLV-I carriers.

    abstract：OBJECTIVES:To describe the frequency of urologic manifestations in human T-cell lymphotropic virus type I (HTLV-I) seropositive individuals from Salvador and other cities in Bahia, Brazil, with or without clinical HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHODS:A total of 218 HTLV-I seropo...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2007.01.052

    authors： Castro NM,Rodrigues W Jr,Freitas DM,Muniz A,Oliveira P,Carvalho EM

    更新日期：2007-05-01 00:00:00

  • Scrotal incision orchiopexy for undescended testis.

    abstract：OBJECTIVES:To evaluate prospectively the success of scrotal incision orchiopexy (Bianchi technique) with or without inguinal hernia in patients with an undescended testis within the inguinal canal or beyond the external inguinal ring. METHODS:A total of 72 orchiopexies were performed in 56 patients with a primary unde...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2004.06.069

    authors： Dayanç M,Kibar Y,Tahmaz L,Yildirim I,Peker AF

    更新日期：2004-12-01 00:00:00

  • Practical utility of specific red cell adherence test in bladder cancer.

    abstract：:There is a highly significant correlation between specific red cell adherence (SRCA) tests for ABO(H) blood group antigens and the biologic potential of a bladder cancer in terms of both superficial tumor recurrences and the subsequent development of invasive cancer. The correlation with superficial recurrences is of ...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/0090-4295(81)90417-9

    authors： Catalona WJ

    更新日期：1981-08-01 00:00:00

  • In Vivo Evaluation of a Novel Pigtail Suture Stent.

    abstract：OBJECTIVE:To compare pressure, dilation, and histology in a porcine model after stenting with a pigtail suture stent (PSS)-where the ureteral and bladder component consists of a suture and a double J (DJ) stent. METHODS:Twelve pigs were studied with a PSS (4.8F/MiniJFil®) and DJ stent (4.8F/RocaJJ Soft) inserted in bo...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2020.11.031

    authors： Majdalany SE,Aldoukhi AH,Jung H,Mehra R,Roberts WW,Ghani KR

    更新日期：2020-11-27 00:00:00

  • Urethral Reconstruction in Aging Male Patients.

    abstract：OBJECTIVE:To report stricture characteristics, complications, and treatment outcomes among elderly men undergoing urethral reconstruction. MATERIALS AND METHODS:A retrospective review of urethroplasty cases and outcomes by a single surgeon from 2007 to 2014 was performed. Men were stratified by decade of life at time ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2017.09.029

    authors： Viers BR,Pagliara TJ,Rew CA,Folgosa-Cooley L,Shiang CY,Scott JM,Morey AF

    更新日期：2018-03-01 00:00:00

  • Clinical and Radiographic Factors Associated With Failed Renal Angioembolization: Results From the Multi-institutional Genitourinary Trauma Study (Mi-GUTS).

    abstract：OBJECTIVE:To find clinical or radiographic factors that are associated with angioembolization failure after high-grade renal trauma. MATERIAL AND METHODS:Patients were selected from the Multi-institutional Genito-Urinary Trauma Study. Included were patients who initially received renal angioembolization after high-gra...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2020.10.027

    authors： Armas-Phan M,Keihani S,Agochukwu-Mmonu N,Cohen AJ,Rogers DM,Wang SS,Gross JA,Joyce RP,Hagedorn JC,Voelzke B,Moses RA,Sensenig RL,Selph JP,Gupta S,Baradaran N,Erickson BA,Schwartz I,Elliott SP,Mukherjee K,Smith BP,

    更新日期：2020-10-28 00:00:00

  • Acid phosphatase levels of irrigant solution during transurethral prostatectomy.

    abstract：:The acid phosphatase level of irrigant solution used during transurethral prostate resections was measured in 20 patients. The mean acid phosphatase of the irrigant solution was 45.3 IU/L (S.D. 50.7). The degree of elevation of irrigant acid phosphatase was related to the weight of tissue resected, the duration of the...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(85)90559-x

    authors： O'Donnell PD,Jacks DW,Brizzolara JP

    更新日期：1985-01-01 00:00:00

  • Ureteroscopic biopsy: technique and specimen preparation.

    abstract：:Because tissue samples obtained ureteroscopically are small, the techniques for biopsy and for handling and processing the samples are crucial. Our aim is to describe the biopsy technique in great detail so other centers can reproduce it. Patients were evaluated by retrograde ureteropyelography and ureteroscopy for di...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/S0090-4295(97)00216-1

    authors： Tawfiek E,Bibbo M,Bagley DH

    更新日期：1997-07-01 00:00:00

  • Epigallocatechin Gallate Attenuates Partial Bladder Outlet Obstruction-induced Bladder Injury via Suppression of Endoplasmic Reticulum Stress-related Apoptosis-In Vivo Study.

    abstract：OBJECTIVES:To investigate the protective effect of epigallocatechin gallate (EGCG), a green tea extract, on partial bladder outlet obstruction (pBOO)-induced bladder injury in a rat model. METHODS:The female Sprague-Dawley rats underwent sham or BOO procedures, and were divided into several groups (sham with saline in...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2015.12.020

    authors： Hsieh JT,Kuo KL,Liu SH,Shi CS,Chang HC,Lin WC,Chou CT,Hsu CH,Liao SM,Wang ZH,Li CC,Huang KH

    更新日期：2016-05-01 00:00:00

  • Loss of DMBT1 expression in human prostate cancer and its correlation with clinical progressive features.

    abstract：OBJECTIVES:To investigate alterations of DMBT1 in prostate cancer and determine the correlation of its alterations to the clinicopathologic features of prostate cancer. DMBT1 has been proposed as a candidate tumor suppressor gene for epithelial cancer. METHODS:The alterations of DMBT1 expression after treatment with D...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2010.09.023

    authors： Du J,Guan M,Fan J,Jiang H

    更新日期：2011-02-01 00:00:00

  • Use of Routine Home Health Care and Deviations From an Uncomplicated Recovery Pathway After Radical Prostatectomy.

    abstract：OBJECTIVE:To evaluate the statistical association between routine home health use after prostatectomy, short-term surgical outcomes, and payments. METHODS:We identified all men who underwent a robotic radical prostatectomy from April 1, 2014, to October 31, 2015, in the Michigan Urological Surgery Improvement Collabor...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2017.11.004

    authors： Kaye DR,Syrjamaki J,Ellimoottil C,Schervish EW,Solomon MH,Linsell S,Montie JE,Miller DC,Dupree JM,Michigan Urological Surgery Improvement Collaborative and the Michigan Value Collaborative.

    更新日期：2018-02-01 00:00:00

  • Therapeutic efficacy of salvage cystectomy. Do results reflect natural history of bladder cancer?

    abstract：:In a retrospective review of patients who underwent salvage cystectomy, patients with muscle-invasive cancers who had initially presented with tumors that were pathologically TA or T1 appeared to have a better prognosis than those who had muscle-invasive (T2 or T3) cancers on initial clinical presentation. Prognosis i...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(83)90489-2

    authors： Droller MJ,Walsh PC

    更新日期：1983-08-01 00:00:00

  • Metabolic Syndrome Predicts Worse Perioperative Outcomes in Patients Treated With Partial Nephrectomy for Renal Cell Carcinoma.

    abstract：OBJECTIVE:To test the association between metabolic syndrome (MetS) and its components (high blood pressure, body mass index [BMI]  ≥ 30, altered fasting glucose, low high-density lipoprotein cholesterol and high triglycerides) on perioperative outcomes after partial nephrectomy (PN). METHODS:Within the National Inpat...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2020.02.019

    authors： Luzzago S,Palumbo C,Rosiello G,Pecoraro A,Deuker M,Stolzenbach F,Mistretta FA,Tian Z,Musi G,Montanari E,Shariat SF,Saad F,Briganti A,de Cobelli O,Karakiewicz PI

    更新日期：2020-06-01 00:00:00

  • Prostate-specific antigen-enhanced testing and risk stratification for chemoprevention trials.

    abstract：:Prostate-specific antigen (PSA) testing could be used to identify men who are at higher future risk of developing clinical prostate cancer or to diagnose prostate cancer earlier in high-risk groups, such as black men or those with a family history of the disease. These cohorts then could be offered chemopreventive cli...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(00)00967-5

    authors： Moul JW

    更新日期：2001-04-01 00:00:00

  • The Role of Therapeutic Layering in Optimizing Treatment for Patients With Castration-resistant Prostate Cancer (Prostate Cancer Radiographic Assessments for Detection of Advanced Recurrence II).

    abstract：OBJECTIVE:To offer recommendations on identification of disease progression, treatment management strategies, and suggestions on timing of initiating and discontinuing specific castration-resistant prostate cancer (CRPC) treatments. MATERIALS AND METHODS:The Prostate Cancer Radiographic Assessments for Detection of Ad...

    journal_title：Urology

    pub_type： 杂志文章,评审

    doi：10.1016/j.urology.2016.12.033

    authors： Crawford ED,Petrylak DP,Shore N,Saad F,Slovin SF,Vogelzang NJ,Keane TE,Koo PJ,Gomella LG,O'Sullivan JM,Tombal B,Concepcion RS,Sieber P,Stone NN,Finkelstein SE,Yu EY,Prostate Cancer Radiographic Assessments for Detection o

    更新日期：2017-06-01 00:00:00

  • A closer look at serum prostatic acid phosphatase as screening test.

    abstract：:Radioimmunoassay techniques for the detection of serum acid phosphatase are reported to provide substantial improvement in test sensitivity and test specificity. Calculation of the positive predictive value for this assay, however, does not support its use as a screening modality. Indiscriminate use of this test may h...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(80)90034-5

    authors： Kiesling VJ Jr,Watson RA

    更新日期：1980-09-01 00:00:00

  • Anuria from candida pyelonephritis and obstructing fungal balls.

    abstract：:A premature newborn male required intensive care and prolonged antibiotic therapy for respiratory distress. Acute renal failure developed from bilateral obstructive candida pyelonephritis complicating systemic Candida albicans infection. Necropsy also revealed organizing subarachnoid hematoma and granulomatous candida...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(83)90171-1

    authors： Khan MY

    更新日期：1983-04-01 00:00:00

  • Bicalutamide (Casodex)-induced prostate regression involves increased expression of genes encoding insulin-like growth factor binding proteins.

    abstract：OBJECTIVES:To examine the effects of bicalutamide (Casodex), a pure antiandrogen with high specificity for the androgen receptor, on insulin-like growth factor binding protein (IGFBP) expression and apoptotic regression of the rat ventral prostate. METHODS:Rats were treated daily with 10 mg/kg body weight bicalutamide...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(99)00421-5

    authors： Nickerson T,Pollak M

    更新日期：1999-12-01 00:00:00

  • Long-term prostate cancer survivors with low socioeconomic status reported worse mental health-related quality of life in a population-based study.

    abstract：OBJECTIVE:To explore whether socioeconomic status (SES) was associated with health-related quality of life (HRQL) and health care use among long-term prostate cancer survivors. PATIENTS AND METHODS:Through urologists in the Comprehensive Cancer Center South, all 5- to 10-year prostate cancer survivors known in the Ein...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2010.06.013

    authors： Aarts MJ,Mols F,Thong MS,Louwman MW,Coebergh JW,van de Poll-Franse LV

    更新日期：2010-11-01 00:00:00

  • Lymphatic vessel hydrodissection during varicocelectomy.

    abstract：:We report a new technique of preserving the lymphatics during varicocelectomy using saline infusion that we have termed "lymphatic hydrodissection." ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2007.04.012

    authors： Atteya A,Amer M,AbdelHady A,Al-Azzizi H,Ismael E,Abdel-Gabbar M,Shamloul R

    更新日期：2007-07-01 00:00:00

  • Role of preoperative urography in benign prostatic hyperplasia.

    abstract：:The excretory urograms of 184 consecutive patients admitted to hospital with a diagnosis of benign prostatic hyperplasia who subsequently underwent prostatectomy were reviewed to determine the usefulness of preoperative urography. Of 184 urograms reviewed, 10 were normal, 136 showed changes consistent with benign pros...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(79)90507-7

    authors： Pang SM,Keresteci AG,Rankin JT,Jewett MA

    更新日期：1979-09-01 00:00:00

  • Prevalence of female sexual dysfunction symptoms and its relationship to quality of life: a Japanese female cohort study.

    abstract：OBJECTIVES:To clarify the age prevalence of female sexual dysfunction and the factors that contribute to the varying frequency of sexual intercourse and satisfaction with sexual life in Japanese women. METHODS:Of 8956 participants (median age 57 years, range 17 to 88) in a Japanese female cohort study, 5042 (56.3%) re...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2004.08.003

    authors： Hisasue S,Kumamoto Y,Sato Y,Masumori N,Horita H,Kato R,Kobayashi K,Hashimoto K,Yamashita N,Itoh N

    更新日期：2005-01-01 00:00:00

  • Ureteral reaction to suture material.

    abstract：:Dog ureters were anastomosed end to end using either chromic catgut, polyglycolic acid (PGA), polyglactin-910, or polypropylene sutures. Analysis of luminal diameters, fibrosis, scar vascularity, and inflammatory reaction four and seven months later indicated that in ureters of the uninfected dog the best results were...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(83)90087-0

    authors： Smith MW,Bartone FF,Tan EC,Gardner PJ

    更新日期：1983-03-01 00:00:00

  • Scrotal calcinosis presenting with prostatitis-like symptoms.

    abstract：:A 47-year-old man complained of a constellation of prostatitis-like symptoms for 4 years. Physical examination revealed a firm nodule within the scrotum. Surgical excision was performed under local anesthesia and microscopic examination confirmed scrotal calcinosis. The patient remained symptom free for at least 12 mo...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/s0090-4295(01)01509-6

    authors： Tsai YS,Tzai TS,Lin JS,Tong YC

    更新日期：2002-01-01 00:00:00

  • Relationship of estimated glomerular filtration rate with lower urinary tract symptoms/benign prostatic hyperplasia measures in middle-aged men with moderate to severe lower urinary tract symptoms.

    abstract：OBJECTIVE:To evaluate the relationship of the glomerular filtration rate (GFR) and lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia measures in middle-aged men. METHODS:A total of 1400 male police officers with moderate and severe LUTS (international prostate symptoms score [IPSS] >7) and aged 40-59 ye...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2013.07.049

    authors： Lee JH,Kwon H,Park YW,Cho IC,Min SK

    更新日期：2013-12-01 00:00:00

  • Miliary tuberculosis following ureteral catheterization.

    abstract：:In a patient with undiagnosed right renal tuberculosis miliary spread to both lungs developed following ureteral catheterization. Mycobacteremia with miliary metastatic foci should be considered as a complication of urinary tract instrumentation in the presence of renal tuberculosis. ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/0090-4295(80)90084-9

    authors： Yekanath H,Gross PA,Vitenson JH

    更新日期：1980-08-01 00:00:00

  • Contemporary evaluation of the D'amico risk classification of prostate cancer.

    abstract：OBJECTIVES:In 1998, D'Amico et al. suggested a model stratifying patients with prostate cancer into those with low, intermediate, or high-risk of biochemical recurrence after surgery according to the clinical TNM stage, biopsy Gleason score, and preoperative prostate-specific antigen level. We studied the performance a...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2007.08.055

    authors： Hernandez DJ,Nielsen ME,Han M,Partin AW

    更新日期：2007-11-01 00:00:00

  • Changing trends in the American diet and the rising prevalence of kidney stones.

    abstract：OBJECTIVE:To evaluate the trends in the American diet over the last 40 years (1974-2010), during which time the National Health and Nutrition Examination Survey data set has documented an increase in stone prevalence from 3.8% to 8.8%. MATERIALS AND METHODS:We used the National Health and Nutrition Examination Survey ...

    journal_title：Urology

    pub_type： 杂志文章

    doi：10.1016/j.urology.2014.06.037

    authors： De SK,Liu X,Monga M

    更新日期：2014-11-01 00:00:00