Abstract：
:A review and meta-analysis by Hamer et al. (2006) showed that a single session of exercise can attenuate post-exercise blood pressure (BP) responses to stress, but no studies examined the effects among smokers or with brisk walking. Healthy volunteers (n=60), averaging 28 years of age and smoking 15 cigarettes daily, abstained from smoking for 2 h before being randomly assigned to a 15-min brisk semi-self-paced walk or passive control condition. Subject characteristics, typical smoking cue-elicited cravings and BP were assessed at baseline. After each condition, BP was assessed before and after three psycho-social stressors were carried out: (1) computerised Stroop word-colour interference task, (2) speech task and (3) only handling a lit cigarette. A two-way mixed ANCOVA (controlling for baseline) revealed a significant overall interaction effect for time by condition for both systolic blood pressure (SBP) and diastolic blood pressure (DBP). Univariate ANCOVAs (to compare between-groups post-stressor BP, controlling for pre-stressor BP) revealed that exercise attenuated systolic BP and diastolic BP responses to the Stroop and speech tasks and SBP to the lit cigarette equivalent to an attenuated SBP and DBP of up to 3.8 mmHg. Post-exercise attenuation effects were moderated by resting blood pressure and self-reported smoking cue-elicited craving. Effects were strongest among those with higher blood pressure and smokers who reported typically stronger cravings when faced with smoking cues. Blood pressure responses to the lit cigarette were not associated with responses to the Stroop and speech task. A self-paced 15-min walk can reduce smokers' SBP and DBP responses to stress, of a magnitude similar on average to non-smokers.
journal_name
Psychopharmacology (Berl)journal_title
Psychopharmacologyauthors
Taylor A,Katomeri Mdoi
10.1007/s00213-005-0275-1subject
Has Abstractpub_date
2006-01-01 00:00:00pages
247-53issue
2eissn
0033-3158issn
1432-2072journal_volume
184pub_type
杂志文章,随机对照试验abstract：RATIONALE:Though interoceptive properties of antidepressants have been described, discriminative stimulus (DS) properties of mirtazapine, which does not affect monoamine reuptake, remain uncharacterized. OBJECTIVES:The objectives of the study are to train rats to recognize a mirtazapine DS, then perform substitution s...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-008-1259-8
更新日期：2009-04-01 00:00:00
abstract：RATIONALE:Although psilocybin has been used for centuries for religious purposes, little is known scientifically about its acute and persisting effects. OBJECTIVES:This double-blind study evaluated the acute and longer-term psychological effects of a high dose of psilocybin relative to a comparison compound administer...
journal_title：Psychopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00213-006-0457-5
更新日期：2006-08-01 00:00:00
abstract：RATIONALE:Clinical observations have shown that pain sensitivity is altered in some schizophrenic patients. OBJECTIVES:To study alterations in pain sensitivity, the ketamine model in schizophrenia research was employed. MATERIALS AND METHODS:Rats were subchronically injected with the dissociative anaesthetic ketamine...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-006-0557-2
更新日期：2006-12-01 00:00:00
abstract：:Mice ran in a circular runway. Some received milk at every third circuit in a designated direction, clockwise or counterclockwise, in daily 1000-s sessions. Under control conditions, about 10 times as many circuits were made in the reinforced direction as in the non-reinforced direction. Cocaine (10, 30, 100 microM/kg...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02244125
更新日期：1990-01-01 00:00:00
abstract：RATIONALE:The Scheduled High Alcohol Consumption (SHAC) binge drinking model is a simple, partial murine model with which to investigate some of the neurobiological underpinnings of alcoholism. OBJECTIVES:The SHAC model was used to characterize monoamine and amino acid adaptations produced in the nucleus accumbens (NA...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-006-0641-7
更新日期：2007-03-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF00571413
更新日期：1978-01-31 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02245152
更新日期：1992-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00181243
更新日期：1986-01-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02244948
更新日期：1993-01-01 00:00:00
abstract：RATIONALE:Serotonin (5-HT) plays a key role in different aspects of value-based decision-making. A recent framework proposed that tonic 5-HT (together with dopamine, DA) codes future average reward expectations, providing a baseline against which possible choice outcomes are compared to guide decision-making. OBJECTIV...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-018-4913-9
更新日期：2018-07-01 00:00:00
abstract：:Withdrawal was precipitated by naloxone at different intervals, up to 22.5 h, following a last maintenance injection in morphine-dependent rats. Different symptoms of withdrawal were found to be preeminent following different morphine-naloxone intervals. Locomotor activity, jumping, and writhing were precipitated most...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00426773
更新日期：1977-10-20 00:00:00
abstract：RATIONALE:Although the effects of D: -cycloserine (DCS) and valproic acid (VPA) on the facilitation of the extinction of fear-conditioned memory have been elucidated in animals, these effects have not been clearly confirmed in humans. OBJECTIVE:This study aimed to determine the effect of DCS (100 mg) and VPA (400 mg) ...
journal_title：Psychopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00213-011-2353-x
更新日期：2011-12-01 00:00:00
abstract：:Previous studies have shown that dihydropyridine (DHP) calcium channel blockers can potentiate yawning induced by apomorphine in rats. The present study was undertaken to examine whether or not this interaction was seen with other compounds that induce yawning or if it represented a specific interaction with dopaminer...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02244401
更新日期：1990-01-01 00:00:00
abstract：RATIONALE:Salvinorin A, the primary psychoactive derivative of the hallucinogenic herb Salvia divinorum, is a potent and highly selective kappa-opioid receptor (KOR) agonist. Several recent studies, however, have suggested endocannabinoid system mediation of some of its effects. OBJECTIVES:This study represents a syst...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-010-1827-6
更新日期：2010-06-01 00:00:00
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journal_title：Psychopharmacology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002130000528
更新日期：2000-09-01 00:00:00
abstract：RATIONALE:Morphine and buprenorphine have analgesic and anxiolytic-like properties. While their analgesic effects have been well characterized, their anxiolytic-like properties have not. OBJECTIVES:Effects of acute morphine and buprenorphine on the expression of acoustic fear-potentiated startle (FPS) and naloxone pre...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-008-1112-0
更新日期：2008-06-01 00:00:00
abstract：:A theory of acute tolerance to alcohol is proposed that includes two assumptions: 1) acute tolerance is a linear process with time, and 2) the slope of the line is a measure of the magnitude of the acute tolerance effect. Evidence that supports the validity of the theory is presented both from studies in which blood a...
journal_title：Psychopharmacology
pub_type： 杂志文章,评审
doi：10.1007/BF02245438
更新日期：1994-02-01 00:00:00
abstract：:In order to assess the possible effects of central GABA activation on the consolidation of shock avoidance, the GABA-T inhibitor amino-oxyacetic acid (AOAA) was administered posttrial to adult male rats. Learning was assessed over nine widely spaced sessions of 20 trials each. AOAA-treated animals showed learning with...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00431848
更新日期：1978-03-01 00:00:00
abstract：RATIONALE:Training in research ethics is crucial for psychiatric investigators. Addressing ethical dimensions of human subjects research requires knowledge about the rules and norms governing research; sensitivity to ethical implications of actions; and skills in ethics problem solving. Investigators in training who ar...
journal_title：Psychopharmacology
pub_type： 杂志文章,评审
doi：10.1007/s00213-003-1500-4
更新日期：2003-12-01 00:00:00
abstract：:When injected IP, the M1 muscarinic receptor antagonist pirenzepine dose-dependently induced a deficit in passive avoidance learning in rats. This activity was optimal at 75 mg/kg injected 1 h before the acquisition session. The deficit induced by pirenzepine was antagonized by oxotremorine (0.03-0.3 mg/kg SC) and phy...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00444707
更新日期：1989-01-01 00:00:00
abstract：:The effects of flurazepam (0.0, 0.5, and 3.0 mg/kg) on methylphenidate-induced increases in stereotypy, gnawing, sniffing, and locomotion were evaluated in Swiss-Webster mice in daytime and nighttime experiments. Methylphenidate (50 mg/kg) increased overall stereotypy and stereotyped gnawing behavior; two doses of met...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF00432374
更新日期：1980-01-01 00:00:00
abstract：RATIONALE:Opioid use disorder (OUD) is a major epidemic in the USA. Despite evidence indicating that OUD may be particularly severe for women, preclinical models have yet to establish sex as a major factor in OUD. OBJECTIVES:Here, we examined sex differences in vulnerability to relapse following intermittent access fe...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-020-05750-2
更新日期：2021-01-06 00:00:00
abstract：RATIONALE:Studies about whether or not the cognitive performance of women is influenced by changes in levels of sex steroid hormones across the menstrual cycle have produced ambiguous results. OBJECTIVES:This study tested whether flight simulator performance differs significantly between the menstrual and the luteal p...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s002130100700
更新日期：2001-05-01 00:00:00
abstract：RATIONALE:Elevated whole-blood serotonin (5-HT) is a robust biomarker in ~ 30% of patients with autism spectrum disorders, in which repetitive behavior is a core symptom. Furthermore, elevated whole-blood 5-HT has also been described in patients with pediatric obsessive-compulsive disorder. The 5-HT1B receptor is assoc...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-020-05758-8
更新日期：2021-01-29 00:00:00
abstract：:Rats may produce ultrasonic vocalizations (USV) in threatening situations. USV of adult male rats in association with aversive stimulation was evaluated as a screening method for anxiolytic drugs. The triazolobenzodiazepine alprazolam, the 5-HT uptake inhibitors fluvoxamine and clomipramine, the mixed 5-HT/NA uptake i...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02245095
更新日期：1995-01-01 00:00:00
abstract：RATIONALE:The endocannabinoid system has been implicated in the pathogenesis of major depression (MD) as well as in the mediation of antidepressant drug effects. OBJECTIVES:To analyze CNR1 gene variants in MD and clinical response to citalopram (selective serotonin re-uptake inhibitors [SSRI]). METHODS:The role of CN...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-013-2995-y
更新日期：2013-06-01 00:00:00
abstract：:BIMT 17, the only compound reported to be a full 5-HT1A agonist and a 5-HT2A antagonist at the frontal cortex, was assessed in three animal paradigms sensitive to antidepressants in rats: olfactory bulbectomy (OB), differential-reinforcement-of-low rate 72-s (DRL 72-s) and learned helplessness (LH). In the OB rats, BI...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s002130050474
更新日期：1997-12-01 00:00:00
abstract：RATIONALE:Higher rates of delay discounting, or impulsive choice, may be related to relapse during abstinence reinforcement interventions for cigarette smoking, and a transdermal nicotine patch may attenuate delay discounting. OBJECTIVE:The objectives of this study are to assess the relation between delay discounting ...
journal_title：Psychopharmacology
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00213-006-0627-5
更新日期：2007-03-01 00:00:00
abstract：:Two sets of experiments were carried out to compare the effects of fenfluramine and fluoxetine on consummatory and operant behaviour. In food-deprived rats allowed access to a 35% sucrose solution, an initial period of sucrose consumption was followed by a short period of grooming and exploratory behaviour, later supe...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/BF02245933
更新日期：1990-01-01 00:00:00
abstract：INTRODUCTION:Alterations in protein kinase (PKA) protein levels have been implicated in the regulation of responses to and development of cocaine addiction. However, the contribution of differences in PKA intracellular cascade to the known sex differences in responses to cocaine is not well understood. This study exami...
journal_title：Psychopharmacology
pub_type： 杂志文章
doi：10.1007/s00213-008-1411-5
更新日期：2009-04-01 00:00:00
