Molecular cloning and sequencing of the murine gastrin gene.

abstract：:S100 proteins are acidic calcium-binding proteins present in high concentration in the brain and at lower concentrations in peripheral tissues. Their function remains to be elucidated in many tissues. In this report we show for the first time that S100 proteins stimulate the bovine photoreceptor membrane guanylate cyc...

journal_title：Biochemical and biophysical research communications

authors： Margulis A,Pozdnyakov N,Sitaramayya A

更新日期：1996-01-05 00:00:00

abstract：:This study presents a kinetic analysis of the response to wounding in rice plants. In particular, jasmonic acid, salicylic acid, and lipoxygenase activity were measured in leaves of wounded rice plants during the early tillering phase. The results show that endogenous jasmonic acid transiently increases to a maximum 3...

journal_title：Biochemical and biophysical research communications

authors： Lee A,Cho K,Jang S,Rakwal R,Iwahashi H,Agrawal GK,Shim J,Han O

更新日期：2004-06-04 00:00:00

abstract：:The human immunodeficiency virus type 1 (HIV-1) Tat is a virally encoded protein that dramatically up-regulates viral replication through interactions with the HIV-1 5' long terminal repeat (LTR) and cellular transcription factors. The HIV-1 LTR is divided into three major regions: modulatory, core and TAR. The modula...

journal_title：Biochemical and biophysical research communications

authors： Li X,Josef J,Marasco WA

更新日期：2001-08-24 00:00:00

abstract：:Obesity continues to be one of the most prominent public health dilemmas in the world. The complex interaction among the varied causes of obesity makes it a particularly challenging problem to address. While typical high-fat purified diets successfully induce weight gain in rodents, we have described a more robust mod...

journal_title：Biochemical and biophysical research communications

authors： Johnson AR,Wilkerson MD,Sampey BP,Troester MA,Hayes DN,Makowski L

更新日期：2016-04-29 00:00:00

abstract：:The repair-associated gene XRCC1 was previously cloned by complementing the hamster mutant EM9, which has a high rate of spontaneous SCE and hypersensitivity to DNA damaging agents. In analyzing XRCC1 gene expression, similar levels of steady-state mRNA were found in normal cells, Bloom's syndrome cells with altered S...

journal_title：Biochemical and biophysical research communications

authors： Yoo H,Li L,Sacks PG,Thompson LH,Becker FF,Chan JY

更新日期：1992-07-31 00:00:00

abstract：:Aplastic anemia (AA) is a serious blood system disease that threatens human health. At present, the main cause of this disease is believed to be immune hyperfunction. However, the specific metabolic mode involved in the occurrence of lymphocytes in AA is still unknown. In addition, whether rapamycin, a specific blocke...

journal_title：Biochemical and biophysical research communications

authors： Liu SL,Zhou YM,Tang DB,Zhou N,Zheng WW,Tang ZH,Duan CW,Chen J

更新日期：2019-10-15 00:00:00

abstract：:The vibrational frequency of CO bound to myoglobin can be varied by up to 60 cm-1 by making site-specific mutations in the distal pocket. These changes may result from specific chemical interactions between distal amino acids and the CO or from changes in the electrostatic field of the distal pocket. In this paper, we...

journal_title：Biochemical and biophysical research communications

authors： Decatur SM,Boxer SG

更新日期：1995-07-06 00:00:00

abstract：:A low molecular weight protein (approximately 25,000 D) exhibiting a yellow fluorescence emission peaking at approximately 540 nm was isolated from Vibrio fischeri (strain Y-1) and purified to apparent homogeneity. FMN is the chromophore, but it exhibits marked red shifts in both the absorption (lambda max = 380, 460 ...

journal_title：Biochemical and biophysical research communications

authors： Macheroux P,Schmidt KU,Steinerstauch P,Ghisla S,Colepicolo P,Buntic R,Hastings JW

更新日期：1987-07-15 00:00:00

abstract：:Clones of eukaryotic initiation factor (eIF) 4B from wheat and Arabidopsis thaliana were obtained from cDNA and genomic libraries. The exon/intron organization of the genes from wheat and A. thaliana is very similar. The deduced amino acid sequences for the wheat and Arabidopsis eIF4B proteins showed overall similarit...

journal_title：Biochemical and biophysical research communications

authors： Metz AM,Wong KC,Malmström SA,Browning KS

更新日期：1999-12-20 00:00:00

abstract：:An examination of more than 1600 protein-protein interaction sites indicated that proline is the residue most commonly found near interaction sites. A structural role is distinguished for these proline residues in the flanking segments of protein-protein interaction sites. The unique nature of proline helps protect th...

journal_title：Biochemical and biophysical research communications

authors： Kini RM,Evans HJ

更新日期：1995-07-26 00:00:00

abstract：:During rat liver regeneration, at the onset of S-phase of the first cell cycle, an enhanced mevalonate incorporation into prenylated proteins is observed. The analysis of the lipid moieties of such proteins shows a 20-fold increased content of geraniol and farnesol. The expected increase of farnesylated and geranylger...

journal_title：Biochemical and biophysical research communications

authors： Bruscalupi G,Castellano F,Sacco S,Trentalance A

更新日期：1994-05-16 00:00:00

abstract：:Calcium/calmodulin-dependent protein kinase II (CaM KII) is thought to be involved in the majority of the neuronal functions mediated by intracellular free Ca(2+), and has been implicated in long-term potentiation, learning, and memory. In this work, we have examined in detail the RNA expression pattern for the Drosop...

journal_title：Biochemical and biophysical research communications

authors： Rachidi M,Lopes C,Takamatsu Y,Ohsako S,Benichou JC,Delabar JM

更新日期：1999-07-14 00:00:00

abstract：:Actin is a highly abundant cytoskeletal protein that is essential for all eukaryotic cells and participates in many structural and functional roles. It has long been noted that estrogen affects cellular morphology. However, recent studies observed that both estrogen and tamoxifen induce a remarkable cytoskeletal remod...

journal_title：Biochemical and biophysical research communications

authors： Wang Z,Sun L,Liang S,Liu ZC,Zhao ZY,Yang J,Wang D,Yang DQ

更新日期：2019-08-27 00:00:00

abstract：:The olfactomedin-domain has been first identified in olfactomedin, an extracellular matrix protein of the olfactory neuroepithelium. Members of this extracellular domain-family have since been shown to be present in several metazoan proteins, such as latrophilins, myocilins, and noelins, but their biological function ...

journal_title：Biochemical and biophysical research communications

authors： Nagy I,Trexler M,Patthy L

更新日期：2003-03-14 00:00:00

abstract：:We have previously demonstrated that the cyclin-dependent kinase inhibitor (Cki) Sic1 of Saccharomyces cerevisiae is phosphorylated in vitro by the CK2 kinase on Ser(201) residue. Moreover, we have collected evidence showing that Sic1 is functionally and structurally related to mammalian Cki p27(Kip1) and binds to the...

journal_title：Biochemical and biophysical research communications

authors： Barberis M,Pagano MA,Gioia LD,Marin O,Vanoni M,Pinna LA,Alberghina L

更新日期：2005-11-04 00:00:00

abstract：:The bright bioluminescence of copepod Metridia longa is conditioned by a small secreted coelenterazine-dependent luciferase (MLuc). To date, three isoforms of MLuc differing in length, sequences, and some properties were cloned and successfully applied as high sensitive bioluminescent reporters. In this work, we repor...

journal_title：Biochemical and biophysical research communications

authors： Larionova MD,Markova SV,Vysotski ES

更新日期：2017-01-29 00:00:00

abstract：:Recently it has been shown that vascular endothelial cells (EC) are completely devoid of apoptosis if cultivated under a steady laminar flow and that apoptosis is induced by turning off the flow. An autocrine loop of thrombospondin-1 (TSP-1) and the alpha(v)beta(3) integrin/integrin-associated protein (IAP) complex ha...

journal_title：Biochemical and biophysical research communications

authors： Freyberg MA,Kaiser D,Graf R,Buttenbender J,Friedl P

更新日期：2001-08-10 00:00:00

abstract：:Hand-foot skin reaction (HFSR) is a common side effect of multiple tyrosine kinase inhibitors (mTKIs). HFSR can necessitate dose reductions or interruption of therapy owing to its negative effect on the quality of life. Therefore, effective use of mTKIs requires measures to prevent HFSR. We evaluated the effect of pro...

journal_title：Biochemical and biophysical research communications

authors： Shichiri H,Yamamoto K,Tokura M,Ishida T,Uda A,Bito T,Nishigori C,Nakagawa T,Hirano T,Yano I,Hirai M

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Chronic hypoxia plays an important role in the initiation and progression of chronic renal disease. The pathogenic role of chronic hypoxia in tubulointerstitial injury has been investigated widely, but little is known about acute hypoxia implications in glomerular damage. In this study, we investigated the e...

journal_title：Biochemical and biophysical research communications

authors： Hu G,He Y,Li Y,Hu X,Liu S,Liao C,Zhang R,Zhou X,Sun H

更新日期：2021-01-12 00:00:00

abstract：:We investigated immunohistochemically the localization of p33, an endogenous substrate protein for an arginine-specific ADP-ribosyltransferase in chicken liver. Polymorphonuclear-pseudo-eosinophilic granulocytes (heterophils) in interlobular connective tissues of the liver were exclusively and strongly stained with th...

journal_title：Biochemical and biophysical research communications

authors： Osago H,Mishima K,Tsuchiya M,Tanigawa Y,Umeno T,Shimoyama M

更新日期：1991-10-15 00:00:00

abstract：:We have used site-directed mutagenesis to investigate the requirement of cysteine residues in the extracellular domains of the human VIP 1 receptor for binding VIP. Cys37, Cys50, Cys63, Cys72, Cys86, Cys105 and Cys122 (N-terminal extracellular domain), Cys208 and Cys215 (second extracellular loop) and Cys288 (third ex...

journal_title：Biochemical and biophysical research communications

authors： Gaudin P,Couvineau A,Maoret JJ,Rouyer-Fessard C,Laburthe M

更新日期：1995-06-26 00:00:00

abstract：:DNA topoisomerase II (Topo II) is an essential enzyme that catalyzes topological changes of DNA and consists of a major member of mitotic chromosomes. To investigate the dynamic localization of Topo II in nuclei, we engineered the strain of Aspergillus nidulans expressing Topo II fused with green fluorescent protein (...

journal_title：Biochemical and biophysical research communications

authors： Kawagishi M,Akashi T,Kikuchi A

更新日期：2005-08-26 00:00:00

abstract：:Bone Morphogenetic Proteins (BMPs) strongly induce the recruitment and differentiation of mesenchymal progenitor cells into mature osteoblasts, but also directly and indirectly stimulate differentiation of osteoclast progenitor cells and acceleration of mature osteoclasts function leading excessive bone resorption. Bi...

journal_title：Biochemical and biophysical research communications

authors： Ichikawa K,Ohta Y,Mamoto K,Mizokawa S,Minoda Y,Imai Y,Takaoka K,Nakamura H

更新日期：2016-11-18 00:00:00

abstract：:WRKY transcription factors are key regulators in regulating abiotic or biotic stress response in Arabidopsis. Previous studies showed that WRKY30 expression was induced by oxidative stress treatment, fungal elicitor, SA and ABA. However, functions of WRKY30 on viral defense are not well studied. Here, we found that Ar...

journal_title：Biochemical and biophysical research communications

authors： Zou L,Yang F,Ma Y,Wu Q,Yi K,Zhang D

更新日期：2019-09-10 00:00:00

abstract：:To help clarify bases for the molecular weight and surface charge heterogeneities of forms of somatic angiotensin converting enzyme (ACE), we examined for differences in N-glycosylation. ACE preparations purified from human, guinea pig, rat and rabbit tissues were found to be heterogeneous in terms of numbers of N-gly...

journal_title：Biochemical and biophysical research communications

authors： Ripka JE,Ryan JW,Valido FA,Chung AY,Peterson CM,Urry RL

更新日期：1993-10-29 00:00:00

abstract：:Antiserum raised against horseradish peroxidase (HRP) recognizes neural specific carbohydrate antigens in Drosophila and other insects. The occurrence of the antigens in mammalian cells was investigated. Proteins were extracted from rat pheochromocytoma cells, PC12, and various tissue of rat and bovine origin, and fur...

journal_title：Biochemical and biophysical research communications

authors： Kurosaka A,Tsuyuki Y,Tahara S

更新日期：1994-10-14 00:00:00

abstract：:Two genes that hybridize to the cDNA for alcohol-inducible cytochrome P-450 form 3a (P-450ALC) have been isolated from a rabbit genomic library and characterized by restriction mapping, hybridization, and partial sequence analysis. The genes show extensive sequence similarity as judged by hybridization at high stringe...

journal_title：Biochemical and biophysical research communications

authors： Khani SC,Porter TD,Coon MJ

更新日期：1988-01-15 00:00:00

abstract：:In vitro produced mammalian embryos suffer from developmental failure, with a large proportion showing embryonic retardation, degradation, or apoptosis. This failure is due, in part, to incomplete oocyte cytoplasmic maturation. C-type natriuretic peptide (CNP) has been reported to act as a meiotic inhibitor. Here we e...

journal_title：Biochemical and biophysical research communications

authors： Zhang T,Fan X,Li R,Zhang C,Zhang J

更新日期：2018-02-26 00:00:00

abstract：:Researchers frequently use 3T3-L1 adipocytes as a fat cell line, but the capacity of this line for insulin-mediated glucose transport is lower than that of primary isolated fat cells. In this study, we found that 5-azacytidine (5-aza-C), DNA methyltransferase 1 inhibitor, enhanced insulin-stimulated 2-deoxyglucose (2-...

journal_title：Biochemical and biophysical research communications

authors： Kuroda M,Onoyama R,Sasaki W,Sebe M,Kitamura T,Masumoto S,Tsutsumi R,Harada N,Sakaue H

更新日期：2020-02-16 00:00:00

abstract：:In human platelets, the amounts of triphosphoinositides (TPI) and diphosphoinositides (DPI) increase after 30 sec and level off after 120 sec of thrombin stimulation. After 180 sec of thrombin challenge, TPI and DPI increase accounts for 66 and 80%, respectively. Polyphosphoinositide changes roughly parallel the relea...

journal_title：Biochemical and biophysical research communications

authors： Perret BP,Plantavid M,Chap H,Douste-Blazy L

更新日期：1983-01-27 00:00:00