Abstract：
:One in every 1,000 newborn suffers from congenital hearing impairment. More than 60% of the congenital cases are caused by genetic factors. In most cases, hearing loss is a multifactorial disorder caused by both genetic and environmental factors. Molecular genetics of deafness has experienced remarkable progress in the last decade. Genes responsible for hereditary hearing impairment are being mapped and cloned progressively. This review focuses on non-syndromic hearing loss, since the gene involved in this type of hearing loss have only recently begun to be identified.
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
Piatto VB,Nascimento EC,Alexandrino F,Oliveira CA,Lopes AC,Sartorato EL,Maniglia JVdoi
10.1016/s1808-8694(15)31313-6subject
Has Abstractpub_date
2005-03-01 00:00:00pages
216-23issue
2eissn
1808-8694issn
1808-8686pii
S1808-8694(15)31313-6journal_volume
71pub_type
杂志文章,评审abstract：INTRODUCTION:The electrophysiological responses obtained with the complex auditory brainstem response (cABR) provide objective measures of subcortical processing of speech and other complex stimuli. The cABR has also been used to verify the plasticity in the auditory pathway in the subcortical regions. OBJECTIVE:To co...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2016.11.002
更新日期：2016-12-08 00:00:00
abstract：INTRODUCTION:An ongoing discussion is found in medical literature about the reasons for changes in thyroid carcinoma incidence patterns over the last decades. OBJECTIVE:To analyze the clinical and pathological characteristics of thyroid carcinoma cases over a decade. METHODS:Cross-sectional study over an historical c...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.07.015
更新日期：2015-09-01 00:00:00
abstract：INTRODUCTION:Adenotonsillectomy is an invasive surgical procedure, which may encourage the search for information by the lay population through online search engines. The quality of this information, however, requires an evaluation due to the wide diversity of the available content. OBJECTIVE:To evaluate the quality, ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2019.06.012
更新日期：2019-07-27 00:00:00
abstract：UNLABELLED:Aging can alter temporal processing and affect speech perception. AIM:To compare temporal processing auditory processing in elderly subject to and new hearing aid users. MATERIALS AND METHODS:The study included 60 elderly patients with bilateral sensorineural hearing loss. The procedures selected were the ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2012-07-01 00:00:00
abstract：INTRODUCTION:The biological processes involved in noise-induced hearing loss (NIHL) are still unclear. The involvement of inflammation in this condition has been suggested. OBJECTIVE:To investigate the association between interleukin - 6 (IL-6) polymorphism and susceptibility to NIHL. METHODS:This was a cross-section...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.07.001
更新日期：2014-09-01 00:00:00
abstract：INTRODUCTION:Mutations in the otoferlin gene are responsible for auditory neuropathy. OBJECTIVE:To investigate the prevalence of mutations in the mutations in the otoferlin gene in patients with and without auditory neuropathy. METHODS:This original cross-sectional case study evaluated 16 index cases with auditory ne...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.03.005
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Amyloidosis is the term applied to a diverse group of disorders that share the features of deposition of amorphous, extracellular material at various sites. Amyloid deposits may occur locally or may involve various organs, resulting number of clinical manifestations. Amyloidosis of the head and neck is rare ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type：
doi：10.1016/j.bjorl.2020.11.011
更新日期：2020-12-19 00:00:00
abstract：INTRODUCTION:Several surgical techniques have been used during tonsillectomy to reduce complications. OBJECTIVES:To assess the effects of pillar suture in conjunction with tonsillectomy as compared to tonsillectomy without suture in children. METHODS:Two authors independently searched five databases (PubMed, SCOPUS, ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2019.12.007
更新日期：2020-01-25 00:00:00
abstract：UNLABELLED:The cervical lymph nodes are relevant due to the diversity of clinical entities. The use of immunohistochemistry is a real method to elucidate the diagnosis of adenopathy, both primary and metastatic neoplasms. OBJECTIVE:To assess the value of immunohistochemistry in the diagnosis of cervical lymph nodes ma...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20130112
更新日期：2013-09-01 00:00:00
abstract：UNLABELLED:Oral lichen planus is one of the most common dermatological diseases presenting in the oral cavity; the prevalence in the general population is 1% to 2%. Although relatively frequent, oral lichen planus is the target of much controversy, especially in relation to its potential for malignancy. AIM:This study...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/s1808-8694(15)31102-2
更新日期：2008-03-01 00:00:00
abstract：UNLABELLED:The search for experimental (animal) models is essential to the development of clinical studies. AIM:To demonstrate, by means of micro dissection techniques, the anatomical structures of temporal bones from the primate Callithrix sp. STUDY DESIGN:Experimental. METHODS:Dissection of temporal bone structure...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30570-x
更新日期：2008-05-01 00:00:00
abstract：INTRODUCTION:Worldwide, hepatitis B virus, hepatitis C virus, and human immunodeficiency virus are major health problems. Healthcare workers are at risk of transmitting blood-borne viruses, and surgeons have a higher risk of exposure to blood and higher rates of percutaneous injury than other healthcare workers. Septop...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2016.10.008
更新日期：2016-11-17 00:00:00
abstract：UNLABELLED:Aging is a natural consequence of a society developing process. The city of São Paulo has almost one million people who are above sixty years of age. Age-related hearing loss equals the total hearing loss resulted from cell degeneration caused by noise exposure, ototoxic agents and the loss caused by disorde...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31123-x
更新日期：2007-01-01 00:00:00
abstract：UNLABELLED:Saccades are part of the electrooculography tests battery. The cerebellum has important connections with the brainstem and thalamic structures involved in the generation of saccades. AIM:to study saccadic movements in subjects with cerebellar disorders. STUDY METHOD:Prospective clinical study. MATERIALS A...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:Children may require tracheostomy due to many different health conditions. Over the last 40 years, indications of tracheostomy have endorsed substantial modifications. OBJECTIVE:To evaluate pediatric patients warranted tracheostomy at our Hospital, in regard to their indications, associated comorbidities,...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2016.08.002
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Preventing or reversing hearing loss is challenging in Ménière's disease. Betahistine, as a histamine agonist, has been tried in controlling vertigo in patients with Ménière's disease, but its effectiveness on hearing problems is not known. OBJECTIVE:To examine the effect of betahistine on hearing functio...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2015.08.021
更新日期：2016-09-01 00:00:00
abstract：UNLABELLED:Graves's disease is the most common cause of hyperthyroidism. There are three current therapeutic options: anti-thyroid medication, surgery, and radioactive iodine (I 131). There are few data in the literature regarding the effects of radioiodine therapy on the larynx and voice. The aim and the AIM:os this ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31092-2
更新日期：2008-03-01 00:00:00
abstract：INTRODUCTION:Tinnitus is sound perception in the absence of a sound source. Changes in parameters of latency and amplitude on the auditory event related potentials or long latency potentials waves have been cited in tinnitus patients when compared to a control group. OBJECTIVE:To perform an assessment of scientific ev...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2019.09.005
更新日期：2020-01-01 00:00:00
abstract：INTRODUCTION:Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this symptom, which often is poorly...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.bjorl.2015.04.016
更新日期：2016-05-01 00:00:00
abstract：UNLABELLED:Conventional CT and MRI scans have low specificity when it comes to differentiating granulation tissue from relapsing cholesteatoma. AIM:this paper aims to analyze the use of DWI and delayed post-contrast T1-weighed imaging in the detection of recurring cholesteatomas. MATERIALS AND METHOD:this is a cross-...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/S1808-8694(15)31378-1
更新日期：2008-09-01 00:00:00
abstract：INTRODUCTION:Abused children and adolescents are exposed to factors that can trigger vocal changes. OBJECTIVE:This study aimed to analyze the prevalence of vocal changes in abused children and adolescents, through auditory-perceptual analysis of voice and the study of the association between vocal changes, communicati...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：UNLABELLED:Cleft lip and palate (CLP) is a risk indicator to middle ear alterations, which may damage the development of auditory abilities such as attention that is essential to learn new skills, oral and written communication. Studies on attention process with CLP population are recent and poorly explored in the spec...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
abstract：UNLABELLED:The possibility of needing a combined access, with neck and chest incisions makes the treatment of substernal goiter a challenge both in the pre-op and the intraoperative. We hereby, discuss a standardization of the surgical technique to minimize the need for a chest approach, making the substernal goiter a ...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)30774-6
更新日期：2009-03-01 00:00:00
abstract：UNLABELLED:Hyperbaric oxygen therapy (HBOT) has enhanced the prevention and treatment of auditory ailments such as ototoxicity. OBJECTIVE:To study the effects of HBOT upon ototoxic injuries produced by amikacin. METHOD:This experimental study included 12 albino guinea pigs, whose auditory function was assessed throug...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.5935/1808-8694.20130060
更新日期：2013-05-01 00:00:00
abstract：INTRODUCTION AND AIMS:the Internet is the world's fastest growing source of health related information. Parents and guardians are increasingly turning to the Internet for information about their children's medical conditions and treatments. This paper has the following objectives 1) determine the prevalence of web sear...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：UNLABELLED:Halitosis is an embarrassing symptom with a significant social impact. Halitosis affects millions of people worldwide and many resources are spent annually in products to improve halitus, unsuccessfully. The study of halitosis in a scientific basis is justified once halitosis causes social restriction, decre...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章,评审
doi：10.1016/S1808-8694(15)31180-0
更新日期：2007-11-01 00:00:00
abstract：UNLABELLED:Frontonasal dysplasia (FND) is a rare malformative complex affecting the frontal portion of the face, the eyes and the nose; it may occur singly or associated with other clinical signs. No systematic studies describing hearing in this condition were found. AIM:To evaluate hearing sensitivity and sound stimu...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1590/s1808-86942011000500013
更新日期：2011-09-01 00:00:00
abstract：UNLABELLED:The research involving tissue factors, such as granulocyte macrophage colonies stimulating factor (GM-CSF) and interleukin 5 (IL-5), leads to the mechanisms involved in the maintenance of eosinophilia, which is essential for the pathogenesis on eosinophilic nasal polyps. Mitomycin C has been successfully use...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/s1808-8694(15)31199-x
更新日期：2005-07-01 00:00:00
abstract：INTRODUCTION:Salivary gland tumors are a diverse group of lesions, with various origins and extremely different behaviors, leading to a variety of outcomes for patients. Therefore, the need to discover novel markers with the ability to predict the behavior of benign and malignant salivary gland neoplasms is crucial. Sy...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1016/j.bjorl.2019.07.006
更新日期：2019-09-04 00:00:00
abstract：UNLABELLED:Obstructive sleep apnea syndrome (OSAS) is one of the most complex disorders of sleep; it involves several genetic factors that contribute to the phenotype. Serotonin (5-HT) regulates a variety of visceral and physiological functions, including sleep. Gene 5-HTR2A polymorphisms may change the transcription o...
journal_title：Brazilian journal of otorhinolaryngology
pub_type： 杂志文章
doi：10.1590/s1808-86942011000300013
更新日期：2011-06-01 00:00:00
