Abstract:
UNLABELLED:Sjögren's Syndrome is an autoimmune disease of the exocrine glands, mainly salivary and lachrymal glands. There is no gold standard test for diagnosis. AIM:evaluation of the importance of minor salivary gland biopsy and sialometry, isolated or associated, as methods for classification of Sjögren's Syndrome. STUDY DESIGN:Transversal cohort. PATIENTS AND METHOD:Seventy-two patients that reported dry mouth from January 1997 to September 2003 were investigated and classified, based on the established criteria. Non-stimulated sialometry was performed by the swab technique. Histopathology exams were evaluated for the presence of inflammatory focus. RESULTS:Non-stimulated sialometry and minor salivary gland biopsy presented different sensitivities for primary Sjögren's Syndrome and for secondary Sjögren's Syndrome. Focal sialadenitis with higher focus score was characteristic of primary Sjögren's Syndrome. Biopsy and sialometry were compared and it was observed that specificity and positive predictive value of biopsy were higher. Comparing biopsy and biopsy associated with sialometry, it was observed that biopsy had higher sensitivity and negative predictive value. Specificity of biopsy associated with sialometry was higher. Comparing sialometry and biopsy associated with sialometry, it was observed that biopsy associated with sialometry presented higher positive predictive value and higher specificity. Sialometry's sensitivity was higher. CONCLUSIONS:Sialometry and biopsy tests presented different performances in primary Sjögren's Syndrome and secondary Sjögren's Syndrome; the positivity of the association of both tests increases the specificity for Sjögren's Syndrome (95%).
journal_name
Braz J Otorhinolaryngoljournal_title
Brazilian journal of otorhinolaryngologyauthors
de Azevedo BB,Bussoloti Filho Idoi
/S0034-72992005000300014subject
Has Abstractpub_date
2005-05-01 00:00:00pages
346-54issue
3eissn
1808-8694issn
1808-8686pii
S1808-8694(15)31334-3journal_volume
71pub_type
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journal_title:Brazilian journal of otorhinolaryngology
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journal_title:Brazilian journal of otorhinolaryngology
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更新日期:2020-12-19 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
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更新日期:2008-07-01 00:00:00
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pub_type: 杂志文章
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30601-7
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pub_type: 杂志文章
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更新日期:2014-11-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-05-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)30967-8
更新日期:2006-05-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2012-06-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2010-11-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
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更新日期:2011-03-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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更新日期:2006-07-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/s1808-8694(15)31123-x
更新日期:2007-01-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章,评审
doi:10.1016/j.bjorl.2015.04.013
更新日期:2016-01-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2020.03.006
更新日期:2020-04-27 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
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更新日期:2020-10-10 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:10.1016/j.bjorl.2017.12.001
更新日期:2019-01-01 00:00:00
abstract:UNLABELLED:Hearing impairment (HI) is characterized by unilateral hearing loss in one ear and can result in learning difficulties, language impairment and socio-emotional difficulties. To assess the perception of hearing handicap in adult subjects, patients with unilateral sensorineural HI, non-users of individual hear...
journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-05-01 00:00:00
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journal_title:Brazilian journal of otorhinolaryngology
pub_type: 杂志文章
doi:
更新日期:2010-07-01 00:00:00