Abstract:
PURPOSE:To evaluate the effect of a computer-aided diagnosis (CAD) system on the diagnostic performance of radiologists for the estimation of the malignancy of pulmonary nodules on thin-section helical computed tomographic (CT) scans. MATERIALS AND METHODS:The institutional review board approved use of the CT database; informed specific study-related consent was waived. The institutional review board approved participation of radiologists; informed consent was obtained from all observers. Thirty-three (18 malignant, 15 benign) pulmonary nodules of less than 3.0 cm in maximal diameter were evaluated. Receiver operating characteristic (ROC) analysis with a continuous rating scale was used to compare observer performance for the estimation of the likelihood of malignancy first without and then with the CAD system. The participants were 10 board-certified radiologists and nine radiology residents. RESULTS:For all 19 participants, the mean area under the best-fit ROC curve (A(z)) values achieved without and with the CAD system were 0.843 +/- 0.097 (standard deviation) and 0.924 +/- 0.043, respectively. The difference was significant (P = .021). The mean A(z) values achieved without and with the CAD system were 0.910 +/- 0.052 and 0.944 +/- 0.040, respectively, for the 10 board-certified radiologists (P = .190) and 0.768 +/- 0.078 and 0.901 +/- 0.036, respectively, for the nine radiology residents (P = .009). CONCLUSION:Use of the CAD system significantly (P = .009) improved the diagnostic performance of radiology residents for assessment of the malignancy of pulmonary nodules; however, it did not improve that of board-certified radiologists.
journal_name
Radiologyjournal_title
Radiologyauthors
Awai K,Murao K,Ozawa A,Nakayama Y,Nakaura T,Liu D,Kawanaka K,Funama Y,Morishita S,Yamashita Ydoi
10.1148/radiol.2383050167subject
Has Abstractpub_date
2006-04-01 00:00:00pages
276-84issue
1eissn
0033-8419issn
1527-1315pii
2383050167journal_volume
239pub_type
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