Abstract:
:Over 4 million people in the United States are chronically infected with hepatitis C virus (HCV), and, if untreated, over 20% of these will progress to more serious disease. Persons with severe mental illness (SMI) have markedly elevated rates of HCV infection, but treatment of persons with SMI and HCV has been controversial. Effective antiviral treatment is available, but side effects include depression and other neuropsychiatric symptoms. This article reviews the available data on neuropsychiatric side effects of interferon (IFN) treatment, discusses the limitations of the current research, and makes recommendations regarding HCV treatment in persons with SMI.
journal_name
Psychosomaticsjournal_title
Psychosomaticsauthors
Mistler LA,Brunette MF,Marsh BJ,Vidaver RM,Luckoor R,Rosenberg SDdoi
10.1176/appi.psy.47.2.93subject
Has Abstractpub_date
2006-03-01 00:00:00pages
93-107issue
2eissn
0033-3182issn
1545-7206pii
S0033-3182(06)70001-9journal_volume
47pub_type
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