Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont.

abstract：:Although any genotype-phenotype relationships are a result of evolution, little is known about how natural selection and neutral drift, two distinct driving forces of evolution, operate to shape the relationships. By analyzing ∼500 yeast quantitative traits, we reveal a basic "supervisor-worker" gene architecture unde...

journal_title：Molecular biology and evolution

authors： Chen H,Wu CI,He X

更新日期：2018-03-01 00:00:00

abstract：:Males and females often have marked phenotypic differences, and the expression of these dissimilarities invariably involves sex differences in gene expression. Sex-biased gene expression has been well characterized in animal species, where a high proportion of the genome may be differentially regulated in males and fe...

journal_title：Molecular biology and evolution

authors： Lipinska A,Cormier A,Luthringer R,Peters AF,Corre E,Gachon CM,Cock JM,Coelho SM

更新日期：2015-06-01 00:00:00

abstract：:For populations to maintain optimal fitness, harmful mutations must be efficiently purged from the genome. Yet, under circumstances that diminish the effectiveness of natural selection, such as the process of plant and animal domestication, deleterious mutations are predicted to accumulate. Here, we compared the load ...

journal_title：Molecular biology and evolution

authors： Renaut S,Rieseberg LH

更新日期：2015-09-01 00:00:00

abstract：:Microarray platforms are used increasingly to make comparative inferences through genome-wide surveys of gene expression. Although recent studies focus on describing the evidence for natural selection using estimates of the within- and between-taxa mutational variances, these methods do not explicitly or flexibly acco...

journal_title：Molecular biology and evolution

authors： Eng KH,Bravo HC,Keleş S

更新日期：2009-10-01 00:00:00

abstract：:The major histocompatibility complex (MHC) class II molecule consists of noncovalently associated alpha and beta chains. In mammals studied so far, the class II MHC can be divided into a number of regions, each containing one or more alpha-chain genes (A genes) and beta-chain genes (B genes), and it has been known for...

journal_title：Molecular biology and evolution

authors： Hughes AL,Nei M

更新日期：1990-11-01 00:00:00

abstract：:There are many examples of groups (such as birds, bees, mammals, multicellular animals, and flowering plants) that have undergone a rapid radiation. In such cases, where there is a combination of short internal and long external branches, correctly estimating and rooting phylogenetic trees is known to be a difficult p...

journal_title：Molecular biology and evolution

authors： Shavit L,Penny D,Hendy MD,Holland BR

更新日期：2007-11-01 00:00:00

abstract：:Hybridization in plants may result in hybrid speciation or introgression and, thus, is now widely understood to be an important mechanism of species diversity on an evolutionary timescale. Hybridization is particularly common in ferns, as is polyploidy, which often results from hybrid crosses. Nevertheless, hybrid spe...

journal_title：Molecular biology and evolution

authors： Wang J,Dong S,Yang L,Harris A,Schneider H,Kang M

更新日期：2020-09-01 00:00:00

abstract：:A recent study conducted the first genome-wide scan for selection in Inuit from Greenland using single nucleotide polymorphism chip data. Here, we report that selection in the region with the second most extreme signal of positive selection in Greenlandic Inuit favored a deeply divergent haplotype that is closely rela...

journal_title：Molecular biology and evolution

authors： Racimo F,Gokhman D,Fumagalli M,Ko A,Hansen T,Moltke I,Albrechtsen A,Carmel L,Huerta-Sánchez E,Nielsen R

更新日期：2017-03-01 00:00:00

abstract：:The emergence of islands has been linked to spectacular radiations of diverse organisms. Although penguins spend much of their lives at sea, they rely on land for nesting, and a high proportion of extant species are endemic to geologically young islands. Islands may thus have been crucial to the evolutionary diversifi...

journal_title：Molecular biology and evolution

authors： Cole TL,Ksepka DT,Mitchell KJ,Tennyson AJD,Thomas DB,Pan H,Zhang G,Rawlence NJ,Wood JR,Bover P,Bouzat JL,Cooper A,Fiddaman SR,Hart T,Miller G,Ryan PG,Shepherd LD,Wilmshurst JM,Waters JM

更新日期：2019-04-01 00:00:00

abstract：:Genetic incompatibilities are commonly observed between hybridizing species. Although this type of isolating mechanism has received considerable attention, we have few examples describing how genetic incompatibilities evolve. We investigated the evolution of two loci involved in a classic example of a Bateson-Dobzhans...

journal_title：Molecular biology and evolution

authors： Scarpino SV,Hunt PJ,Garcia-De-Leon FJ,Juenger TE,Schartl M,Kirkpatrick M

更新日期：2013-10-01 00:00:00

abstract：:Clines in chromosomal inversion polymorphisms-presumably driven by climatic gradients-are common but there is surprisingly little evidence for selection acting on them. Here we address this long-standing issue in Drosophila melanogaster by using diagnostic single nucleotide polymorphism (SNP) markers to estimate inver...

journal_title：Molecular biology and evolution

authors： Kapun M,Fabian DK,Goudet J,Flatt T

更新日期：2016-05-01 00:00:00

abstract：:Phylogenetic inference from genome-wide data (phylogenomics) has revolutionized the study of evolution because it enables accounting for discordance among evolutionary histories across the genome. To this end, summary methods have been developed to allow accurate and scalable inference of species trees from gene trees...

journal_title：Molecular biology and evolution

authors： Zhang C,Scornavacca C,Molloy EK,Mirarab S

更新日期：2020-11-01 00:00:00

abstract：:Complex metazoan bodies require cell-to-cell communication for development, a process often mediated by signaling molecules binding to specific receptors. Relatively few signaling pathways have been recruited during evolution to build multicellular animals from unicellular zygotes. Of these few signaling pathways, one...

journal_title：Molecular biology and evolution

authors： Bertrand S,Iwema T,Escriva H

更新日期：2014-02-01 00:00:00

abstract：:The Environment for Tree Exploration (ETE) is a computational framework that simplifies the reconstruction, analysis, and visualization of phylogenetic trees and multiple sequence alignments. Here, we present ETE v3, featuring numerous improvements in the underlying library of methods, and providing a novel set of sta...

journal_title：Molecular biology and evolution

authors： Huerta-Cepas J,Serra F,Bork P

更新日期：2016-06-01 00:00:00

abstract：:Insertion and deletion (indel)-based analyses have great potential for rooting the tree of life, but their use has been limited because they require ubiquitous sequences that have not been horizontally/laterally transferred. Very few such sequences exist. Here we describe and demonstrate a new algorithm that can use n...

journal_title：Molecular biology and evolution

authors： Lake JA,Herbold CW,Rivera MC,Servin JA,Skophammer RG

更新日期：2007-01-01 00:00:00

abstract：:Ecological diversity in fungi is largely defined by metabolic traits, including the ability to produce secondary or "specialized" metabolites (SMs) that mediate interactions with other organisms. Fungal SM pathways are frequently encoded in biosynthetic gene clusters (BGCs), which facilitate the identification and cha...

journal_title：Molecular biology and evolution

authors： Gluck-Thaler E,Haridas S,Binder M,Grigoriev IV,Crous PW,Spatafora JW,Bushley K,Slot JC

更新日期：2020-10-01 00:00:00

abstract：:Endogenous retroviruses are genomic elements formed by germline infiltration by originally exogenous viruses. These molecular fossils provide valuable information about the evolution of the retroviral family. Lentiviruses are an extensively studied genus of retroviruses infecting a broad range of mammals. Despite a we...

journal_title：Molecular biology and evolution

authors： Hron T,Farkašová H,Padhi A,Pačes J,Elleder D

更新日期：2016-10-01 00:00:00

abstract：:The diversity and evolution of bitter taste perception in mammals is not well understood. Recent discoveries of bitter taste receptor (T2R) genes provide an opportunity for a genetic approach to this question. We here report the identification of 10 and 30 putative T2R genes from the draft human and mouse genome seque...

journal_title：Molecular biology and evolution

authors： Shi P,Zhang J,Yang H,Zhang YP

更新日期：2003-05-01 00:00:00

abstract：:The transposable element hobo has been introduced into the previously empty Drosophila melanogaster strain Hikone so that its dynamics can be followed and it can be compared with the P element. Five transformed lines were followed over 58 generations. The results were highly dependent on the culture temperature, the s...

journal_title：Molecular biology and evolution

authors： Galindo MI,Ladevèze V,Lemeunier F,Kalmes R,Periquet G,Pascual L

更新日期：1995-09-01 00:00:00

abstract：:Liver and intestinal flukes of the family Fasciolidae cause zoonotic food-borne infections that impact both agriculture and human health throughout the world. Their evolutionary history and the genetic basis underlying their phenotypic and ecological diversity are not well understood. To close that knowledge gap, we c...

journal_title：Molecular biology and evolution

authors： Choi YJ,Fontenla S,Fischer PU,Le TH,Costábile A,Blair D,Brindley PJ,Tort JF,Cabada MM,Mitreva M

更新日期：2020-01-01 00:00:00

abstract：:The selective constraints influencing mRNA editing in plant organelles are largely unknown. To investigate these, we compared patterns of editing between monocot and dicot mitochondrial mRNA. On average, 24% of sites that are edited form C to U in one species have been substituted during evolution by a genomic T in th...

journal_title：Molecular biology and evolution

authors： Shields DC,Wolfe KH

更新日期：1997-03-01 00:00:00

abstract：:Most phenotypic traits are controlled by many genes, but a global picture of the genotype-phenotype map (GPM) is lacking. For example, in no species do we know generally how many genes affect a trait and how large these effects are. It is also unclear to what extent GPMs are shaped by natural selection. Here we addres...

journal_title：Molecular biology and evolution

authors： Ho WC,Zhang J

更新日期：2014-06-01 00:00:00

abstract：:Male reproductive fitness is strongly affected by seminal fluid. In addition to interacting with the female environment, seminal fluid mediates important physiological characteristics of sperm, including capacitation and motility. In mammals, the male reproductive tract shows a striking degree of compartmentalization,...

journal_title：Molecular biology and evolution

authors： Dean MD,Clark NL,Findlay GD,Karn RC,Yi X,Swanson WJ,MacCoss MJ,Nachman MW

更新日期：2009-08-01 00:00:00

abstract：:In all anthropoid species, the coding region of the involucrin gene contains a segment of short tandem repeats that were added sequentially, beginning in a common anthropoid ancestor. The involucrin coding region of each of two platyrrhine species, the white-fronted capuchin (Cebus albifrons) and the cottontop tamarin...

journal_title：Molecular biology and evolution

authors： Phillips M,Rice RH,Djian P,Green H

更新日期：1991-09-01 00:00:00

abstract：:Analysis of mitochondrial DNA restriction fragment length polymorphism in European anchovy (Engraulis encrasicolus) revealed a large number of mitotypes that form two distinct clusters (phylads). Phylad A consists of one common mitotype and many rare secondary mitotypes that are one mutational step removed from the ma...

journal_title：Molecular biology and evolution

authors： Magoulas A,Tsimenides N,Zouros E

更新日期：1996-01-01 00:00:00

abstract：:Next-generation sequencing opened up new possibilities in phylogenetics; however, choosing an appropriate method of sample preparation remains challenging. Here, we demonstrate that restriction-site-associated DNA sequencing (RAD-seq) generates useful data for phylogenomics. Analysis of our RAD library using current b...

journal_title：Molecular biology and evolution

authors： Cruaud A,Gautier M,Galan M,Foucaud J,Sauné L,Genson G,Dubois E,Nidelet S,Deuve T,Rasplus JY

更新日期：2014-05-01 00:00:00

abstract：:Baleen whales (suborder Mysticeti) comprise 11 extant species that are classified into four families. Although several phylogenetic hypotheses about these taxa have been proposed, their phylogenetic relationships remain confused. We addressed this problem using short interspersed repetitive element (SINE) insertion da...

journal_title：Molecular biology and evolution

authors： Nikaido M,Hamilton H,Makino H,Sasaki T,Takahashi K,Goto M,Kanda N,Pastene LA,Okada N,SMBE Tri-National Young Investigators.

更新日期：2006-05-01 00:00:00

abstract：:The evolution of DNA base composition evolution is simplified to a six-parameter model when there are no strand biases for mutation and selection. We analyzed the dynamics of this model with special attention to the influence of a change in substitution rates. The G + C content of the DNA sequence tends to an equilibr...

journal_title：Molecular biology and evolution

authors： Lobry JR,Lobry C

更新日期：1999-06-01 00:00:00

abstract：:In the past 40 years, there has been increasing acceptance that variation in levels of gene expression represents a major source of evolutionary novelty. Gene expression divergence is therefore likely to be involved in the emergence of incipient species, namely, in a context of adaptive radiation. In the lake whitefis...

journal_title：Molecular biology and evolution

authors： Jeukens J,Bittner D,Knudsen R,Bernatchez L

更新日期：2009-01-01 00:00:00

abstract：:In primates, the craniofacial skeleton and the dentition are marked by high levels of interspecific variation. Despite this, there are few comparative species studies conducted at the molecular level to investigate this functional diversity. We have determined nucleotide sequences of MSX1 and PAX9, two developmental g...

journal_title：Molecular biology and evolution

authors： Perry GH,Verrelli BC,Stone AC

更新日期：2006-03-01 00:00:00