Forskolin-associated luteinizing hormone release by rat anterior pituitary glands: effects of castration and estradiol replacement.

abstract：:Measurements of electrical activity and intracellular Ca(2+) levels were performed in perforated-patch clamped GH(3) cells to determine the contribution of large-conductance calcium-activated K(+) (BK) channels to action potential repolarization and size of the associated Ca(2+) oscillations. By examining the dependen...

journal_title：Neuroendocrinology

authors： Miranda P,de la Peña P,Gómez-Varela D,Barros F

更新日期：2003-03-01 00:00:00

abstract：:Hypothalamic norepinephrine (NE) and dopamine content was studied in dogs with spontaneous and iatrogenic hypercortisolism and in untreated normal dogs. The concentration of NE in the hypothalamus was subnormal in 4 of 8 dogs with pituitary-dependent hyperadrenocorticism (PDH), whereas long-term administration of cort...

journal_title：Neuroendocrinology

authors： Meijer JC,Croughs RJ,Rijnberk A,Versteeg DH,van Ree JM

更新日期：1981-04-01 00:00:00

abstract：:Both the pituitary-adrenal axis and the pituitary-gonadal axis are under the tonic inhibitory control of endogenous opioid peptides in man. However, the precise opioid receptor involved in the modulation of these hormones remains unknown. The effect of a dose of intravenous naloxone on serum levels of luteinising horm...

journal_title：Neuroendocrinology

authors： Grossman A,Moult PJ,Cunnah D,Besser M

更新日期：1986-01-01 00:00:00

abstract：:The release of the decapeptide gonadotropin-releasing hormone (GnRH) from neuroterminals in the median eminence varies depending upon the stage of development, time of day, reproductive season, and day of the ovarian cycle. With respect to the biosynthetic events responsible for such alterations in GnRH release, we ha...

journal_title：Neuroendocrinology

authors： Gore AC

更新日期：1998-10-01 00:00:00

abstract：:Thymic neuroendocrine neoplasms are rare tumours, but their management can often be highly problematic. While previously assumed to be essentially variants of bronchopulmonary (lung) carcinoids, they are generally more aggressive and more difficult to treat. Some 25% are associated with multiple endocrine neoplasia-1,...

journal_title：Neuroendocrinology

authors： Jia R,Sulentic P,Xu JM,Grossman AB

更新日期：2017-01-01 00:00:00

abstract：:The timing of the episodic secretion of luteinizing hormone (LH) in ovariectomized ewes was investigated with respect to an ultradian rest-activity cycle. Individual sheep were enclosed in a chamber where their physical activity was continuously monitored, and blood samples for LH analysis were collected at 5-min inte...

journal_title：Neuroendocrinology

authors： Rasmussen DD,Malven PV

更新日期：1981-06-01 00:00:00

abstract：:At present there is no clinical guideline or standardised protocol for the treatment of metastatic or invasive phaeochromocytoma and paraganglioma (collectively known as PPGL) due to the rarity of the disease and the lack of prospective studies or extended national databases. Prognosis is mainly determined by genetic ...

journal_title：Neuroendocrinology

authors： Mak IYF,Hayes AR,Khoo B,Grossman A

更新日期：2019-01-01 00:00:00

abstract：:Steroid autoradiography was undertaken to determine the neuroanatomical loci which might be involved in the activation of steroid-sensitive behaviors in the Japanese quail (Coturnix japonica). Male and female quail were either surgically gonadectomized or photically regressed and implanted with androgen or estrogen to...

journal_title：Neuroendocrinology

authors： Watson JT,Adkins-Regan E

更新日期：1989-01-01 00:00:00

abstract：:The present study was designed to investigate the role of glucocorticoids in mediating the stimulatory effect of interleukin-1 (IL-1) upon the adrenocortical (AC) axis. Intact male rats were injected with either vehicle or dexamethasone (DEX) (5-50 micrograms/100 g b.w.) and were subsequently exposed to ether stress o...

journal_title：Neuroendocrinology

authors： Weidenfeld J,Abramsky O,Ovadia H

更新日期：1989-12-01 00:00:00

abstract：:We have previously shown that the serotonergic regulation of renin secretion from the kidneys is mediated by a renin-releasing factor (RRF) that is present in both plasma and hypothalamus. The present studies were designed to determine the distribution of RRF in the brain and peripheral tissues and to test whether RRF...

journal_title：Neuroendocrinology

authors： Urban JH,Brownfield MS,Levine JE,Van de Kar LD

更新日期：1992-05-01 00:00:00

abstract：:This study examines the neural lobe of the pituitary gland for the presence of receptors for pituitary adenylate cyclase-activating polypeptide (PACAP) and their possible involvement in the regulation of neurosecretion. The presence of PACAP receptors of type I was revealed in the neural lobe, as well as in anterior a...

journal_title：Neuroendocrinology

authors： Lutz-Bucher B,Monnier D,Koch B

更新日期：1996-08-01 00:00:00

abstract：:We have investigated the variations in growth hormone (GH) and somatostatin (SOM) mRNAs in adult, middle-aged and aging rats of both sexes using quantitative in situ hybridization. cDNA probes complementary to GH mRNA and SOM mRNA were used on fixed pituitary and hypothalamic sections, respectively. A clear sexual dim...

journal_title：Neuroendocrinology

authors： Martinoli MG,Ouellet J,Rhéaume E,Pelletier G

更新日期：1991-12-01 00:00:00

abstract：:Previous studies have shown that the hypothalamic concentration of pro-opiomelanocortin (POMC) mRNA and several POMC-derived peptides increases in the rat 4 weeks after orchiectomy and that this increase can be prevented by testosterone replacement. In this study, we have examined the short-term effects of orchiectomy...

journal_title：Neuroendocrinology

authors： Wardlaw SL,Blum M

更新日期：1990-11-01 00:00:00

abstract：:Rats bearing transplanted prolactin-secreting tumors are known to have very high prolactin levels in the serum, reduced hypothalamic opiate concentrations, increasing hypothalamic dopamine synthesis and increased hypophyseal portal blood dopamine levels. Further, it has been shown that incubation in 3H-leucine of ante...

journal_title：Neuroendocrinology

authors： Login IS,Nagy I,MacLeod RM

更新日期：1981-08-01 00:00:00

abstract：:The level of thyroid hormone in blood has been acutely decreased by about 20--30% within 20 min with the aid of isovolemic exchange transfusion (IET) of thyroid hormone free blood cell suspension (THFBCS) in three groups of rats: (1) intact control (C); (2) median eminence (ME)-lesioned; (3) thalamus (TH)-lesioned. Th...

journal_title：Neuroendocrinology

authors： Langer P,Földes O,Mess B,Kokesová H,Gschwendtová K

更新日期：1977-01-01 00:00:00

abstract：:Lewis (LEW) and Fischer 344 (F344) rats differ in responsiveness of the hypothalamo-pituitary-adrenocortical (HPA) axis as well as in their behavioral responses to drugs of abuse. The present experiments were conducted to compare hypothalamic corticotropin-releasing factor (CRF), plasma adrenocorticotropic hormone (AC...

journal_title：Neuroendocrinology

authors： Simar MR,Saphier D,Goeders NE

更新日期：1996-01-01 00:00:00

abstract：AIM:To extensively explore microRNA expression profiles in lung carcinoids in correlation with clinical and pathological features. METHODS:A PCR-based array was employed in the screening phase to analyze 752 microRNAs in a discovery set of 12 lung carcinoids, including 6 typical (3 with lymph node metastasis) and 6 at...

journal_title：Neuroendocrinology

authors： Rapa I,Votta A,Felice B,Righi L,Giorcelli J,Scarpa A,Speel EJ,Scagliotti GV,Papotti M,Volante M

更新日期：2015-01-01 00:00:00

abstract：:Hyponatremia due to elevated arginine vasopressin (AVP) secretion increases mortality in liver failure patients. The mechanisms causing dysregulation of AVP secretion are unknown. Our hypothesis is that inappropriate AVP release associated with liver failure is due to increased brain-derived neurotrophic factor (BDNF)...

journal_title：Neuroendocrinology

authors： Balapattabi K,Little JT,Bachelor M,Cunningham JT

更新日期：2020-01-01 00:00:00

abstract：:The site of inhibitory action of glucocorticoids on the hypothalamic corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) was studied using a combination of glucocorticoid implantation and immunohistochemistry. Adrenalectomy increased the number and the staining intensity of the neurons containing CRF-l...

journal_title：Neuroendocrinology

authors： Kovács K,Kiss JZ,Makara GB

更新日期：1986-01-01 00:00:00

abstract：:The ability of dopamine receptor antagonists to stimulate prolactin release in rats with medial basal hypothalamic lesions was investigated. Starting levels of prolactin were elevated to approximately 400 ng/ml in animals in which the tuberoinfundibular dopaminergic neurons were completely destroyed by the lesion. In ...

journal_title：Neuroendocrinology

authors： Cheung CY,Neill AC,Weiner RI

更新日期：1981-06-01 00:00:00

abstract：:Central or systemic administration of morphine disrupts maternal behavior in steroid-primed, pup-induced virgin and lactating rats. Morphine, the prototypical mu agonist, also interacts with different opioid receptor subtypes. The present study examined the effectiveness of five receptor-selective agonists, in additio...

journal_title：Neuroendocrinology

authors： Mann PE,Kinsley CH,Bridges RS

更新日期：1991-05-01 00:00:00

abstract：:In the primate, arginine vasopressin (AVP) is known to activate the hypothalamo-pituitary-adrenal axis and to inhibit LH secretion. In the present study, we investigate the role of the endogenous opioid peptides and corticotropin-releasing hormone (CRH) in these processes. Adult ovariectomized rhesus monkeys bearing a...

journal_title：Neuroendocrinology

authors： Xiao E,Xia-Zhang L,Thornell D,Shalts E,Ferin M

更新日期：1996-09-01 00:00:00

abstract：:During adult-onset peripheral hypothyroidism, the brain maintains normal levels of thyroid hormone for some time through a mechanism of 'central homeostasis'. Although onset, duration, and termination of such a homeostatic phenomenon have been recently evaluated in rat models, the mechanism behind remains unknown. Dur...

journal_title：Neuroendocrinology

authors： Kundu S,Roy S,De J,Biswas A,Pramanik M,Ray AK

更新日期：2007-01-01 00:00:00

abstract：:Prolactin release from primary cultured pituitary cells was investigated using a dynamic perifusion system. Although epinephrine (1 mumol/l) produced an elevation in the mean value of the prolactin concentration at the onset of the perifusion, the elevation was not statistically significant, and the overall effect of ...

journal_title：Neuroendocrinology

authors： Shin SH,Barton RE

更新日期：1993-04-01 00:00:00

abstract：:Thyroid hormones and nitric oxide/cyclic guanosine monophosphate (NO/cGMP) signaling play a significant role in the structural development of the cerebellum, respectively. In the present study, the possible contribution of neuronal NO synthase (NOS) and cGMP in the thyroid hormone-induced structural changes was invest...

journal_title：Neuroendocrinology

authors： Serfozo Z,de Vente J,Elekes K

更新日期：2009-01-01 00:00:00

abstract：:These studies investigated the effect of aging on thyroid hormone regulation of beta-endorphin in rat corpus striatum and hypothalamus. In both brain areas, basal levels of beta-endorphin declined with age. In addition, age modified the response of beta-endorphin to thyroid hormone status. Hypothyroid rats aged 6 mont...

journal_title：Neuroendocrinology

authors： Gambert SR

更新日期：1981-02-01 00:00:00

abstract：:The diuretic action of two new narcotic antagonists, oxilorphan and butorphanol, was studied in rats heterozygous for hereditary hypothalmic diabetes insipidus. Both drugs caused a prompt increase in urine volume and a decrease in urine osmolality with an associated decrease in urinary ADH excretion. The effects appea...

journal_title：Neuroendocrinology

authors： Miller M

更新日期：1975-01-01 00:00:00

abstract：:There is a great deal of conflicting data regarding the issue of whether androgens influence opiate receptors in the whole male rat brain. Although Hahn and Fishman initially reported that long-term castration produced a large increase in the density of opiate-binding sites, relative to controls, no other independent ...

journal_title：Neuroendocrinology

authors： Cicero TJ,O'Connor LH,Bell RD

更新日期：1987-08-01 00:00:00

abstract：:The worldwide obesity epidemic is increasing, yet at this time, no long-acting and specific pharmaceutical therapies are available. Peripheral hormonal signals communicate metabolic status to the hypothalamus by activating their corresponding receptors in the arcuate nucleus (ARC). In this brain region, a variety of G...

journal_title：Neuroendocrinology

authors： Rediger A,Piechowski CL,Habegger K,Grüters A,Krude H,Tschöp MH,Kleinau G,Biebermann H

更新日期：2012-01-01 00:00:00

abstract：:The effects of hepatic vagotomy upon the circadian rhythm of lipogenesis and body fat store levels were tested in seasonally obese Syrian hamsters. Lipogenesis was studied 8 weeks after surgery by measuring the incorporation of label into epididymal and retroperitoneal fat pad lipid in animals killed 30 min after intr...

journal_title：Neuroendocrinology

authors： Martin DD,Cincotta AH,Meier AH

更新日期：1990-07-01 00:00:00