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Role of magnetic resonance and intravascular magnetic resonance in the detection of vulnerable plaques.

Abstract：

:Noninvasive magnetic resonance imaging (MRI) has been used to determine vascular three-dimensional structure, detect the presence of subclinical atherosclerotic disease in high-risk patient subgroups, and optimize and follow therapy in individual patients. The outstanding soft-tissue-characterizing capabilities of MRI permit depiction of various components of atherothrombotic plaque, including lipid, fibrous tissue, calcium, and thrombus formation. However, noninvasive MRI visualization of coronary arteries is currently limited by the small size of the coronary arteries, the deep arterial location, and arterial motion. The combination of MR imaging and molecular probes offers exciting possibilities of direct visualization of biologic processes within atherosclerotic tissue. The self-contained intravascular MRI probe appears to hold promise in the identification of high-risk coronary atherosclerotic lesions with increased superficial lipid content.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Wilensky RL,Song HK,Ferrari VA

doi

10.1016/j.jacc.2005.11.048

subject

Has Abstract

pub_date

2006-04-18 00:00:00

pages

C48-56

issue

8 Suppl

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(05)03141-4

journal_volume

47

pub_type

杂志文章,评审

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