Abstract：
:This study examined the learning abilities of mature rhesus monkeys that had been subjected to bilateral amygdalectomy either during infancy or adulthood. At 4 1/2 years of age, 6 female monkeys that had been amygdalectomized in infancy and 12 neurologically intact controls were trained on a barpress avoidance problem. At 6 years, half the controls were amygdalectomized. At 7 1/2 years, the infant-operated, adult-operated and control monkeys were trained on shock-motivated problems, including a panelpress avoidance and 15 position reversals, and food-motivated problems, including delayed alternation and 15 position reversals. Infant-amygdalectomized monkeys required significantly more sessions than controls to meet the barpress avoidance criterion at 4 1/2 years, and they also took longer to extinguish the response. At 7 1/2 years, neither the infant- nor the adult-operated monkeys exhibited any difficulty with the shock-motivated problems. On the food-motivated problems, however, both amygdalectomy groups made more preservative errors than controls. The cumulative results from this study and from previous studies with these animals suggest that amygdalectomy in infancy produces no long-term sparing of function in monkeys. When infant- and adult-operated monkeys are tested at the same age, their deficits are indistinguishable.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Thompson CIdoi
10.1016/0166-4328(81)90039-5subject
Has Abstractpub_date
1981-01-01 00:00:00pages
81-101issue
1eissn
0166-4328issn
1872-7549pii
0166-4328(81)90039-5journal_volume
2pub_type
杂志文章abstract：:This review describes a series of animal experiments that investigate the role of endogenous adenosine (AD) in sleep. We propose that AD is a modulator of the sleepiness associated with prolonged wakefulness. More specifically, we suggest that, during prolonged wakefulness, extracellular AD accumulates selectively in ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(00)00258-8
更新日期：2000-11-01 00:00:00
abstract：:The ability of the somatosensory cortex in differentiating various tactile sensations is very important for a person to perceive the surrounding environment. In this study, we utilize a lab-made multi-channel functional near-infrared spectroscopy (fNIRS) to discriminate the hemodynamic responses (HRs) of four differen...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.06.034
更新日期：2017-08-30 00:00:00
abstract：:Epidural motor cortex stimulation (MCS) has been used for treating patients with neuropathic pain resistant to other therapeutic approaches. Experimental evidence suggests that the motor cortex is also involved in the modulation of normal nociceptive response, but the underlying mechanisms of pain control have not bee...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2008.07.027
更新日期：2009-01-03 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(99)00128-x
更新日期：2000-01-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2010.03.051
更新日期：2010-09-01 00:00:00
abstract：:Chronic administration of cocaine can cause pronounced and enduring cognitive alterations such as increases in impulsive choice. Chronic cocaine can also result in enhanced dopamine (DA) release in the nucleus accumbens (NAc) in response to reward-related cues. It is possible that this enhanced DA release in the NAc i...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.01.001
更新日期：2017-03-15 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2004.06.007
更新日期：2005-02-10 00:00:00
abstract：:This experiment compared the shortcut choices of able-bodied teenagers with those of physically disabled teenagers who had varying histories of mobility impairment. In a computer-simulated kite-shaped maze, participants were allowed to explore three arms that connected four rooms. Subsequently they were offered a choi...
journal_title：Behavioural brain research
pub_type： 临床试验,杂志文章
doi：10.1016/s0166-4328(02)00097-9
更新日期：2002-10-17 00:00:00
abstract：:Testing of cognitive functions in rodent disease models constitutes a substantial sector of behavioral neuroscience. It is most often needed in phenotyping genetically modified new rodent (usually mouse) lines or in preclinical testing of cognitive effects of new CNS drugs. This review concerns present pitfalls and fu...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/j.bbr.2017.05.040
更新日期：2018-10-15 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.08.022
更新日期：2017-09-29 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.04.017
更新日期：2011-09-30 00:00:00
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journal_title：Behavioural brain research
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2000-07-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.12.014
更新日期：2012-03-17 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2011.09.038
更新日期：2012-01-15 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2017.05.055
更新日期：2017-08-14 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(01)00274-1
更新日期：2001-11-01 00:00:00
abstract：:Environmental enrichment promotes structural and functional changes in the brain, including enhanced learning and memory performance in rodents. Transient global cerebral ischemia (15 min) causes specific damage to dorsal hippocampal area CA1 pyramidal cells of the rat concomitantly with cognitive deficits. Thus, we i...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2003.10.017
更新日期：2004-07-09 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2016.09.006
更新日期：2017-01-01 00:00:00
abstract：:We review some of the evidence for structural changes in synapses in response to environmental stimulation. These include changes in synapse number, in distribution of presynaptic vesicles, in synaptic bouton size, and complex changes in the shape and size of synaptic contact zones. Increased numbers of postsynaptic p...
journal_title：Behavioural brain research
pub_type： 杂志文章,评审
doi：10.1016/0166-4328(94)00116-w
更新日期：1995-01-23 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/s0166-4328(97)02311-5
更新日期：1997-10-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.07.056
更新日期：2015-11-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：1984-07-01 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112022
更新日期：2019-10-17 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
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更新日期：2020-03-02 00:00:00
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journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2014.02.049
更新日期：2014-06-01 00:00:00
abstract：:Because of the organization of visual and motor pathways, simple manual responses to a light stimulus in the right or left visual hemifields are performed faster with uncrossed hand-field combinations than with crossed hand-field combinations. Uncrossed responses can be integrated within a single hemisphere, whereas c...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/0166-4328(94)90126-0
更新日期：1994-10-20 00:00:00
abstract：:Previous data have shown that the rat model of melatonin deficit can cause a number of neurobiological aberrations. The aim of the present study was to determine whether the antidepressant drug agomelatine, a MT1/MT2 melatoninergic receptor agonist/5-HT2C receptor antagonist is able to prevent some of the behavioral, ...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.12.043
更新日期：2016-04-01 00:00:00
abstract：:Perinatal manipulations can lead to neurobehavioural changes in the progeny. In this study we investigated, in adolescent male rat offspring, the consequences of a single, intense prenatal stress induced by a 120 min-maternal immobilization at gestational day 16, and of a daily, brief maternal separation from postnata...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2005.12.010
更新日期：2006-04-25 00:00:00
abstract：:During unilateral hand movements the activity of the contralateral primary motor cortex (cM1) is increased while the activity of the ipsilateral M1 (iM1) is decreased. A potential explanation for this asymmetric activity pattern is transcallosal cM1-to-iM1 inhibitory control. To test this hypothesis, we examined inter...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2015.07.016
更新日期：2015-10-15 00:00:00
abstract：:Synthetic cathinones share potent sympathomimetic properties with amphetamines due to their shared phenethylamine backbone. Despite recent work focused on understanding the behavioral effects of synthetic cathinones, a systematic comparison of neuropharmacology, behavior, and physiological effects with other stimulant...
journal_title：Behavioural brain research
pub_type： 杂志文章
doi：10.1016/j.bbr.2019.112368
更新日期：2020-02-03 00:00:00
